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CASI Pharmaceuticals, Inc. (CASI) 10-Year Financial Performance & Capital Metrics

CASI • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsHematologic Oncology
AboutCASI Pharmaceuticals, Inc., a biopharmaceutical company, develops and commercializes therapeutics and pharmaceutical products in China, the United States, and internationally. It offers EVOMELA, an intravenous formulation of melphalan for use as a conditioning treatment prior to stem cell transplantation, and as a palliative treatment for patients with multiple myeloma. The company's product pipeline includes CNCT19, an autologous CD19 CAR-T investigative product for the treatment of patients with B-cell acute lymphoblastic leukemia (B-ALL) and B-cell non-Hodgkin lymphoma (B-NHL); BI-1206 that is in Phase I/II trial in combination with anti-PD1 therapy Keytruda for solid tumors, and in a Phase I/IIa trial in combination with MabThera (rituximab) in patients with relapsed/refractory NHL; and CB-5339, which is in Phase I clinical trial for acute myeloid leukemia and myelodysplastic syndrome. Its product pipeline also comprises CID-103 for the treatment of patients with multiple myeloma; Thiotepa, which has multiple indications including use as a conditioning treatment for various allogeneic haemopoietic stem cell transplants; and Octreotide long acting injectable formulations for the treatment of acromegaly and for the control of symptoms associated with various neuroendocrine tumors. The company has licensing agreements with Juventas Cell Therapy Ltd; BioInvent International AB; Black Belt Therapeutics Limited; and Cleave Therapeutics, Inc. It also has distribution agreements with China Resources Pharmaceutical Commercial Group International Trading Co., Ltd; Pharmathen Global BV; and Riemser Pharma GmbH. The company was formerly known as EntreMed, Inc. and changed its name to CASI Pharmaceuticals, Inc. in June 2014. CASI Pharmaceuticals, Inc. was incorporated in 1991 and is based in Rockville, Maryland.Show more
  • Revenue $29M -15.8%
  • EBITDA -$37M -74.8%
  • Net Income -$39M -45.7%
  • EPS (Diluted) -2.56 -26.7%
  • Gross Margin 39.06% -34.0%
  • EBITDA Margin -130.67% -107.5%
  • Operating Margin -138.84% -87.6%
  • Net Margin -137.57% -73.0%
  • ROE -301.8% -410.3%
  • ROIC -153% -101.3%
  • Debt/Equity 11.96 +1261.0%
  • Interest Coverage -45.49
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 47.2%
  • ✓Healthy dividend yield of 4.5%

✗Weaknesses

  • ✗High debt to equity ratio of 12.0x
  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 9 (bottom 9%)
  • ✗Shares diluted 14.8% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y103.24%
5Y47.19%
3Y-1.84%
TTM21.72%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-59.58%

EPS CAGR

10Y-
5Y-
3Y-
TTM-41.7%

ROCE

10Y Avg-20.22%
5Y Avg-50.01%
3Y Avg-55.64%
Latest-104.59%

Peer Comparison

Hematologic Oncology
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
INCYIncyte Corporation20.66B105.24701.6014.76%24.69%25.55%1.21%0.01
TGTXTG Therapeutics, Inc.4.88B30.71204.7340.8%13.31%21.87%1.14
AGIOAgios Pharmaceuticals, Inc.1.62B27.802.3936.07%-8.96%-31.24%0.04
CLRBCellectar Biosciences, Inc.15.48M3.65-0.09-200.99%0.03
CASICASI Pharmaceuticals, Inc.21.37M1.04-0.41-15.77%-183.93%-301.8%11.96
VORVor Biopharma Inc.308.06M14.06-0.41-94.52%0.33
FATEFate Therapeutics, Inc.121.12M1.05-0.64-78.55%-21.87%-66.69%0.27
KPTIKaryopharm Therapeutics Inc.121.95M6.66-0.71-0.55%-87.43%

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+47.71K0004.13M15.14M30.17M43.11M33.88M28.54M
Revenue Growth %1.01%-1%---2.67%0.99%0.43%-0.21%-0.16%
Cost of Goods Sold+6.27K66.45K117.78K1.67M3.94M9.51M12.56M15.83M13.83M17.39M
COGS % of Revenue0.13%---0.95%0.63%0.42%0.37%0.41%0.61%
Gross Profit+41.44K-66.45K-117.78K-1.67M196K5.63M17.61M27.28M20.05M11.15M
Gross Margin %0.87%---0.05%0.37%0.58%0.63%0.59%0.39%
Gross Profit Growth %1.55%-2.6%-0.77%-13.19%1.12%27.74%2.13%0.55%-0.26%-0.44%
Operating Expenses+7.19M9.42M10.75M26.5M40.19M58.41M59.13M53.77M45.13M50.77M
OpEx % of Revenue150.78%---9.73%3.86%1.96%1.25%1.33%1.78%
Selling, General & Admin3.12M4.78M3.16M18M30.44M27.48M38.41M37.77M41.84M41.44M
SG&A % of Revenue65.36%---7.37%1.81%1.27%0.88%1.23%1.45%
Research & Development4.08M4.65M7.6M8.51M9.75M11.47M14.42M16M9.86M8.92M
R&D % of Revenue85.42%---2.36%0.76%0.48%0.37%0.29%0.31%
Other Operating Expenses0000019.47M6.3M0-6.57M407K
Operating Income+7.15M9.42M-10.75M-26.5M-39.99M-52.78M-41.52M-26.49M-25.08M-39.62M
Operating Margin %149.91%----9.68%-3.49%-1.38%-0.61%-0.74%-1.39%
Operating Income Growth %-0.73%0.32%-2.14%-1.47%-0.51%-0.32%0.21%0.36%0.05%-0.58%
EBITDA+7.22M9.49M-10.63M-24.83M-37.84M-50.82M-39.7M-24.07M-21.34M-37.29M
EBITDA Margin %151.34%----9.16%-3.36%-1.32%-0.56%-0.63%-1.31%
EBITDA Growth %-0.72%0.31%-2.12%-1.34%-0.52%-0.34%0.22%0.39%0.11%-0.75%
D&A (Non-Cash Add-back)68.38K66.45K117.78K1.67M2.15M1.96M1.81M2.42M3.74M2.33M
EBIT-7.12M-9.42M-10.76M-27.46M-39.58M-33.31M-35.22M-26.49M-25.28M-37.2M
Net Interest Income+-81.53K-26.09K1.01K39.99K1.06M866K321K127K614K-332K
Interest Income9227.72K15.98K48.2K1.06M866K321K189K614K539K
Interest Expense82.45K33.81K14.98K8.21K00062K0871K
Other Income/Expense-54.02K-32.88K-18.88K-967.57K-5.37M5.27M5.67M-11.79M-1.21M1.55M
Pretax Income+-7.21M-9.45M-10.77M-27.47M-45.36M-47.51M-35.84M-38.28M-26.29M-38.07M
Pretax Margin %-151.04%----10.98%-3.14%-1.19%-0.89%-0.78%-1.33%
Income Tax+82.45K33.81K14.98K00001.98M-81K1.19M
Effective Tax Rate %1%1%1%1%1%1.02%1.02%1.07%1.02%1.03%
Net Income+-7.21M-9.45M-10.77M-27.47M-45.36M-48.29M-36.65M-41.01M-26.94M-39.26M
Net Margin %-151.04%----10.98%-3.19%-1.21%-0.95%-0.8%-1.38%
Net Income Growth %0.72%-0.31%-0.14%-1.55%-0.65%-0.06%0.24%-0.12%0.34%-0.46%
Net Income (Continuing)-7.21M-9.45M-10.77M-27.47M-45.36M-47.51M-35.84M-40.26M-26.21M-39.26M
Discontinued Operations0000000000
Minority Interest000020.67M22.03M23.46M22.36M00
EPS (Diluted)+-2.22-1.69-1.75-3.24-4.80-4.37-2.69-3.01-2.02-2.56
EPS Growth %0.76%0.24%-0.04%-0.85%-0.48%0.09%0.38%-0.12%0.33%-0.27%
EPS (Basic)-2.22-1.69-1.75-3.24-4.80-4.37-2.69-3.01-2.02-2.56
Diluted Shares Outstanding3.24M5.59M6.15M8.48M9.59M11.05M13.61M13.65M13.36M15.34M
Basic Shares Outstanding3.24M5.59M6.15M8.48M9.59M11.05M13.61M13.65M13.36M15.34M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+5.57M27.45M43.81M92.56M61.5M74.03M61.97M73.42M59.34M39.58M
Cash & Short-Term Investments5.13M27.09M43.49M85.12M54.25M66.37M48.57M51.34M30.77M16.09M
Cash Only5.13M27.09M43.49M84.2M53.62M57.06M38.7M47.11M17.08M13.47M
Short-Term Investments000912.2K625K9.31M9.87M4.22M13.69M2.62M
Accounts Receivable00001.29M4.64M9.8M12.97M10.14M15.35M
Days Sales Outstanding----114.24111.98118.61109.85109.22196.27
Inventory000283K4.54M1.36M1.91M6.14M15.88M5.25M
Days Inventory Outstanding---61.82421.352.0655.43141.55419.12110.23
Other Current Assets438.23K355.89K322.49K911.81K0002.98M2.56M2.89M
Total Non-Current Assets+256.97K264.08K1.29M20.85M41.13M53.71M76.33M22.81M15.92M13.9M
Property, Plant & Equipment218.8K229.59K1.05M1.75M9.69M10.76M21.82M13.23M11.63M11.36M
Fixed Asset Turnover0.22x---0.43x1.41x1.38x3.26x2.91x2.51x
Goodwill0000000000
Intangible Assets00018.78M16.89M13.21M12.2M1.06M1.84M238K
Long-Term Investments000014.04M29.44M40.13M7.46M1.68M1.72M
Other Non-Current Assets38.17K34.48K242.02K310.02K504K299K2.18M1.06M771K587K
Total Assets+5.83M27.71M45.1M113.41M102.63M127.73M138.3M96.23M75.27M53.67M
Asset Turnover0.01x---0.04x0.12x0.22x0.45x0.45x0.53x
Asset Growth %-0.48%3.76%0.63%1.51%-0.1%0.24%0.08%-0.3%-0.22%-0.29%
Total Current Liabilities+1.05M1.32M5.06M3.87M7.95M7.98M13.19M17M16.73M36.45M
Accounts Payable884.1K1.06M2.09M968K5.11M3.26M4.79M3.29M4.44M2.72M
Days Payables Outstanding51.43K5.85K6.47K211.45474.27125.15139.275.85117.1557.15
Short-Term Debt0001.5M01.29M2.17M0018.39M
Deferred Revenue (Current)4.09K0000001000K1000K1000K
Other Current Liabilities002.23M944-1.18M0-7.62M0010.31M
Current Ratio5.29x20.86x8.65x23.89x7.74x9.28x4.70x4.32x3.55x1.09x
Quick Ratio5.29x20.86x8.65x23.82x7.17x9.11x4.56x3.96x2.60x0.94x
Cash Conversion Cycle----61.2838.8834.83175.55411.19249.35
Total Non-Current Liabilities+10.86M5.61M1.5M73.59K1.02M16.18M17.15M12.3M34.38M15.37M
Long-Term Debt1.46M1.49M1.5M0000018.89M0
Capital Lease Obligations00001.02M965K1.1M476K1.62M2.54M
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities9.4M4.12M073.59K012.87M13.22M11.82M13.87M12.84M
Total Liabilities11.91M6.93M6.56M3.95M8.97M24.16M30.34M29.3M51.1M51.82M
Total Debt+1.46M1.49M1.5M1.5M2.2M3.2M4.33M1.34M21.24M22.14M
Net Debt-3.67M-25.6M-41.99M-82.71M-51.42M-53.87M-34.37M-45.77M4.16M8.67M
Debt / Equity-0.07x0.04x0.01x0.02x0.03x0.04x0.02x0.88x11.96x
Debt / EBITDA0.20x0.16x--------
Net Debt / EBITDA-0.51x-2.70x--------
Interest Coverage86.74x278.65x-717.90x-3229.10x----427.27x--45.49x
Total Equity+-6.09M20.78M38.54M109.46M93.67M103.57M107.96M66.93M24.16M1.85M
Equity Growth %-13.42%4.41%0.85%1.84%-0.14%0.11%0.04%-0.38%-0.64%-0.92%
Book Value per Share-1.883.726.2712.929.769.387.934.901.810.12
Total Shareholders' Equity-6.09M20.78M38.54M109.46M73M81.54M84.5M44.57M24.16M1.85M
Common Stock325.25K602.76K699.01K953.67K979K1.24M1.4M1K1K2K
Retained Earnings-432.48M-441.93M-452.7M-478.94M-523.91M-570.5M-605.64M-637.16M-660.82M-700.08M
Treasury Stock-8.03M-8.03M-8.03M-8.03M-8.03M-8.03M-8.03M-9.33M-9.6M-9.6M
Accumulated OCI-293.53K-262.02K-372.27K-1.23M-2.73M589K1.95M-703K-1.2M-1.77M
Minority Interest000020.67M22.03M23.46M22.36M00

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-5.51M-6.02M-6.4M-28.58M-23.24M-25.89M-26.84M-21.09M-19.97M-29.22M
Operating CF Margin %-115.56%----5.63%-1.71%-0.89%-0.49%-0.59%-1.02%
Operating CF Growth %-0.38%-0.09%-0.06%-3.46%0.19%-0.11%-0.04%0.21%0.05%-0.46%
Net Income-7.21M-9.45M-10.77M-27.47M-45.36M-47.51M-35.84M-40.26M-26.94M-39.26M
Depreciation & Amortization68.38K66.45K117.78K1.67M2.15M1.96M1.81M2.42M3.74M2.33M
Stock-Based Compensation1.54M3M650.44K6.12M7.31M7.82M7.77M7.01M7.22M1.31M
Deferred Taxes-27.51K-5.67K19.89K325.46K1.24M-3.94M-5.2M000
Other Non-Cash Items74.95K26.31K7.48K553.57K6.97M19.1M7.83M16.39M3.83M5.63M
Working Capital Changes36K348.04K3.57M-9.78M4.45M-3.32M-3.22M-6.65M-7.82M771K
Change in Receivables23.73K000-1.29M-3.35M-5.16M-3.17M2.83M-5.21M
Change in Inventory-4.63M00-283K-4.41M3.19M-551K-4.23M-9.74M5.83M
Change in Payables129.47K180.53K849.37K-1.1M4M-1.54M1.49M1.07M1.15M-1.72M
Cash from Investing+-25.4K-64.79K-934.7K-21.77M-28.06M-20.72M-20.69M31.16M-9.67M11.24M
Capital Expenditures-25.4K-223.23K-934.7K-21.77M-14.02M-19.33M-15.5M-5.61M-204K-223K
CapEx % of Revenue0.53%---3.39%1.28%0.51%0.13%0.01%0.01%
Acquisitions----------
Investments----------
Other Investing-25.4K158.45K020.64M-6.97M-1.31M7.03M6.44M-2.04M483K
Cash from Financing+028.05M23.73M92.27M22.05M47.15M29.64M-3.27M-907K15.43M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid00000000-738K-718K
Share Repurchases----------
Other Financing0-96.51K-462.84K4.02M23.36M805K-2.02M001.15M
Net Change in Cash----------
Free Cash Flow+-5.54M-6.25M-7.34M-50.36M-37.26M-45.21M-42.34M-26.7M-22.21M-29.46M
FCF Margin %-116.09%----9.02%-2.99%-1.4%-0.62%-0.66%-1.03%
FCF Growth %-0.24%-0.13%-0.17%-5.86%0.26%-0.21%0.06%0.37%0.17%-0.33%
FCF per Share-1.71-1.12-1.19-5.94-3.88-4.09-3.11-1.96-1.66-1.92
FCF Conversion (FCF/Net Income)0.77x0.64x0.59x1.04x0.51x0.54x0.73x0.51x0.74x0.74x
Interest Paid0000000000
Taxes Paid000000001.81M0

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)--128.65%-36.31%-37.12%-44.66%-48.96%-34.66%-46.9%-59.14%-301.8%
Return on Invested Capital (ROIC)----170.59%-86.93%-86.1%-50.51%-41.94%-76.02%-153%
Gross Margin86.85%---4.74%37.2%58.38%63.28%59.19%39.06%
Net Margin-15104.01%----1098.09%-318.92%-121.5%-95.14%-79.51%-137.57%
Debt / Equity-0.07x0.04x0.01x0.02x0.03x0.04x0.02x0.88x11.96x
Interest Coverage86.74x278.65x-717.90x-3229.10x----427.27x--45.49x
FCF Conversion0.77x0.64x0.59x1.04x0.51x0.54x0.73x0.51x0.74x0.74x
Revenue Growth101.09%-100%---266.52%99.25%42.89%-21.41%-15.77%

Revenue by Segment

2019
E V O M E L A4.1M
E V O M E L A Growth-

Frequently Asked Questions

Growth & Financials

CASI Pharmaceuticals, Inc. (CASI) reported $26.8M in revenue for fiscal year 2024. This represents a 1283% increase from $1.9M in 2011.

CASI Pharmaceuticals, Inc. (CASI) saw revenue decline by 15.8% over the past year.

CASI Pharmaceuticals, Inc. (CASI) reported a net loss of $49.4M for fiscal year 2024.

Dividend & Returns

Yes, CASI Pharmaceuticals, Inc. (CASI) pays a dividend with a yield of 4.50%. This makes it attractive for income-focused investors.

CASI Pharmaceuticals, Inc. (CASI) has a return on equity (ROE) of -301.8%. Negative ROE indicates the company is unprofitable.

CASI Pharmaceuticals, Inc. (CASI) had negative free cash flow of $29.5M in fiscal year 2024, likely due to heavy capital investments.

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