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Milestone Pharmaceuticals Inc. (MIST) 10-Year Financial Performance & Capital Metrics

MIST • • Industrial / General
HealthcareBiotechnologyMetabolic & Liver DiseasesObesity & Metabolic Disorders
AboutMilestone Pharmaceuticals Inc., a biopharmaceutical company, focuses on the development and commercialization of cardiovascular medicines. The company is developing etripamil, a novel channel blocker, which is in Phase III clinical trial for the treatment of paroxysmal supraventricular tachycardia in the United States and Canada; and Phase II clinical trial for the treatment of atrial fibrillation and rapid ventricular rate. It has a license and collaboration agreement with Ji Xing Pharmaceuticals to develop and commercialize etripamil prophylactic and therapeutic uses in humans. The company was incorporated in 2003 and is headquartered in Montréal, Canada.Show more
  • Revenue $0 -100.0%
  • EBITDA -$42M +31.2%
  • Net Income -$42M +30.4%
  • EPS (Diluted) -0.67 +51.8%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -277.55% -93.3%
  • ROIC -64.83% +18.0%
  • Debt/Equity 4.17 +35.0%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗High debt to equity ratio of 4.2x
  • ✗Weak Piotroski F-Score: 2/9
  • ✗Shares diluted 44.8% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-35.65%

EPS CAGR

10Y-
5Y-
3Y-
TTM7.78%

ROCE

10Y Avg-52.98%
5Y Avg-58.06%
3Y Avg-72.53%
Latest-62.2%

Peer Comparison

Obesity & Metabolic Disorders
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Valuation
Per Share
Growth
Profitability
Quality & Returns
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TTM Growth
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Momentum & Returns
Total Return (DRIP)
Technical
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
MNKDMannKind Corporation1.73B5.6458.0243.5%9.32%1.89%
CORTCorcept Therapeutics Incorporated3.82B36.3529.5539.94%14.19%16.65%5.12%0.01
GUTSFractyl Health, Inc. Common Stock308.28M2.01-1.24-22.5%-40732.33%-241.68%2.20
LXRXLexicon Pharmaceuticals, Inc.436.08M1.20-1.9024.81%-96.77%-57.07%0.74
RZLTRezolute, Inc.229.96M2.48-2.53-52.45%0.01
MISTMilestone Pharmaceuticals Inc.164.38M1.93-2.88-100%-282.97%4.17
ALTAltimmune, Inc.418.41M4.01-2.99-95.31%-4195.75%-45.21%0.01
BIOABioAge Labs, Inc.741.84M20.69-3.12-12.81%-27.32%0.03

Profit & Loss

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+000015M5M1M0
Revenue Growth %------0.67%-0.8%-1%
Cost of Goods Sold+8K10K000000
COGS % of Revenue--------
Gross Profit+-8K-10K0015M5M1M0
Gross Margin %----1%1%1%-
Gross Profit Growth %--0.25%1%---0.67%-0.8%-1%
Operating Expenses+8.27M23.82M57.88M50.71M58.07M64.64M62.1M42.1M
OpEx % of Revenue----3.87%12.93%62.1%-
Selling, General & Admin2.63M6.97M15.62M15.9M19.4M24.81M31.05M27.75M
SG&A % of Revenue----1.29%4.96%31.05%-
Research & Development5.64M16.85M42.38M34.86M38.67M39.83M31.05M14.36M
R&D % of Revenue----2.58%7.97%31.05%-
Other Operating Expenses00-115K-55K0000
Operating Income+-8.27M-23.82M-57.88M-50.71M-43.07M-59.64M-61.1M-42.1M
Operating Margin %-----2.87%-11.93%-61.1%-
Operating Income Growth %--1.88%-1.43%0.12%0.15%-0.38%-0.02%0.31%
EBITDA+-8.26M-23.81M-57.84M-50.61M-42.98M-59.55M-61.01M-42M
EBITDA Margin %-----2.87%-11.91%-61.01%-
EBITDA Growth %--1.88%-1.43%0.12%0.15%-0.39%-0.02%0.31%
D&A (Non-Cash Add-back)8K10K38K97K93K89K92K105K
EBIT-8.27M-23.37M-57.88M-50.71M-43.07M-58.39M-57.13M-37.94M
Net Interest Income+0000220K1.25M1.41M7.75M
Interest Income186K711K2.6M726K220K1.25M3.97M4.16M
Interest Expense002.6M726K002.55M-3.58M
Other Income/Expense186K711K2.6M726K220K1.25M1.41M583K
Pretax Income+-8.08M-23.11M55.28M-49.98M-42.85M-58.39M-59.69M-41.52M
Pretax Margin %-----2.86%-11.68%-59.69%-
Income Tax+4K74K56K-17K0000
Effective Tax Rate %1%1%-1%1%1%1%1%1%
Net Income+-8.09M-23.18M-55.23M-49.97M-42.85M-58.39M-59.69M-41.52M
Net Margin %-----2.86%-11.68%-59.69%-
Net Income Growth %--1.87%-1.38%0.1%0.14%-0.36%-0.02%0.3%
Net Income (Continuing)-8.09M-23.18M-55.23M-49.97M-42.85M-58.39M-59.69M-41.52M
Discontinued Operations00000000
Minority Interest00000000
EPS (Diluted)+-0.34-0.98-3.50-1.70-1.02-1.35-1.39-0.67
EPS Growth %--1.88%-2.57%0.51%0.4%-0.32%-0.03%0.52%
EPS (Basic)-0.34-0.98-3.50-1.70-1.02-1.35-1.39-0.67
Diluted Shares Outstanding23.65M23.65M15.78M29.34M41.83M42.45M42.96M62.21M
Basic Shares Outstanding23.65M23.65M15.78M29.34M41.83M42.45M42.96M62.21M
Dividend Payout Ratio--------

Balance Sheet

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+27.55M88.05M122.5M148.69M118.92M71.8M73.03M73.93M
Cash & Short-Term Investments26.91M85.98M119.82M142.31M114.14M64.58M66M69.69M
Cash Only10.88M85.95M119.82M72.31M114.14M7.64M13.76M25.31M
Short-Term Investments16.03M29K070M056.95M52.24M44.38M
Accounts Receivable543K677K00483K1.21M3.85M2.39M
Days Sales Outstanding----11.7588.551.41K-
Inventory00000000
Days Inventory Outstanding--------
Other Current Assets00836K948K0000
Total Non-Current Assets+35K30K929K1.29M926K2.68M2.19M1.57M
Property, Plant & Equipment35K30K929K1.29M926K2.68M2.19M1.57M
Fixed Asset Turnover----16.20x1.87x0.46x-
Goodwill00000000
Intangible Assets00000000
Long-Term Investments00000000
Other Non-Current Assets00000000
Total Assets+27.59M88.08M123.43M149.97M119.85M74.48M75.23M75.5M
Asset Turnover----0.13x0.07x0.01x-
Asset Growth %-2.19%0.4%0.22%-0.2%-0.38%0.01%0%
Total Current Liabilities+1.6M4.53M8.33M6.16M6.78M6.14M7.23M8.13M
Accounts Payable4K2.6M4.38M4.64M4.38M2.26M3.98M1.93M
Days Payables Outstanding182.595.01K------
Short-Term Debt0000224K495K00
Deferred Revenue (Current)00000000
Other Current Liabilities1.11M56K00709K808K1.99M0
Current Ratio17.17x19.42x14.71x24.14x17.55x11.70x10.11x9.10x
Quick Ratio17.17x19.42x14.71x24.14x17.55x11.70x10.11x9.10x
Cash Conversion Cycle--------
Total Non-Current Liabilities+59.1M138.76M184K696K474K2M51.23M54.23M
Long-Term Debt00000049.77M53.35M
Capital Lease Obligations00184K696K474K2M1.46M874K
Deferred Tax Liabilities00000000
Other Non-Current Liabilities59.1M138.76M000000
Total Liabilities60.71M143.29M8.51M6.86M7.25M8.13M58.45M62.35M
Total Debt+00514K941K698K2.49M51.77M54.8M
Net Debt-10.88M-85.95M-119.3M-71.37M-113.44M-5.14M38.02M29.48M
Debt / Equity--0.00x0.01x0.01x0.04x3.09x4.17x
Debt / EBITDA--------
Net Debt / EBITDA--------
Interest Coverage---22.30x-69.85x---23.92x-
Total Equity+-33.12M-55.21M114.92M143.12M112.6M66.35M16.77M13.15M
Equity Growth %--0.67%3.08%0.25%-0.21%-0.41%-0.75%-0.22%
Book Value per Share-1.40-2.337.284.882.691.560.390.21
Total Shareholders' Equity-33.12M-55.21M114.92M143.12M112.6M66.35M16.77M13.15M
Common Stock1.23M2.04M226.25M251.68M251.9M273.9M260.5M288.05M
Retained Earnings-35.09M-58.27M-113.5M-163.47M-206.32M-266.34M-326.03M-367.55M
Treasury Stock00000000
Accumulated OCI-1.63M-1.63M-1.63M46.37M51.31M34.35M48.46M53.08M
Minority Interest00000000

Cash Flow

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-8.05M-21.05M-51.15M-50.73M-33.22M-52.47M-46.42M-28.85M
Operating CF Margin %-----2.21%-10.49%-46.42%-
Operating CF Growth %--1.61%-1.43%0.01%0.35%-0.58%0.12%0.38%
Net Income-8.09M-23.18M-55.23M-49.97M-42.85M-58.39M-59.69M-41.52M
Depreciation & Amortization8K10K38K97K93K89K92K105K
Stock-Based Compensation190K633K1.19M4.95M7.28M9.05M9.53M5.78M
Deferred Taxes00-1.63M00000
Other Non-Cash Items59K787K1.63M0044K2.39M3.13M
Working Capital Changes-164K1.5M2.85M-5.81M2.26M-3.26M1.24M3.66M
Change in Receivables147K-134K-169K-112K465K-730K-2.64M1.46M
Change in Inventory00169K00000
Change in Payables-222K2.88M3.52M-2.08M0000
Cash from Investing+-16.02M16M-384K-70M70M-57.12M4.76M8.28M
Capital Expenditures-36K-5K-413K00-272K-112K-33K
CapEx % of Revenue-----0.05%0.11%-
Acquisitions--------
Investments--------
Other Investing-15.99M16M-35.41M00000
Cash from Financing+30.72M80.11M85.41M73.22M5.05M3.09M47.79M32.12M
Debt Issued (Net)--------
Equity Issued (Net)--------
Dividends Paid00000000
Share Repurchases--------
Other Financing-278K461K44K48.31M5.05M458K-2.21M4.86M
Net Change in Cash--------
Free Cash Flow+-8.09M-21.05M-51.56M-50.73M-33.22M-52.74M-46.54M-28.88M
FCF Margin %-----2.21%-10.55%-46.54%-
FCF Growth %--1.6%-1.45%0.02%0.35%-0.59%0.12%0.38%
FCF per Share-0.34-0.89-3.27-1.73-0.79-1.24-1.08-0.46
FCF Conversion (FCF/Net Income)1.00x0.91x0.93x1.02x0.78x0.90x0.78x0.69x
Interest Paid00000000
Taxes Paid00000000

Key Ratios

Metric20172018201920202021202220232024
Return on Equity (ROE)---185%-38.73%-33.52%-65.26%-143.61%-277.55%
Return on Invested Capital (ROIC)----112.92%-91.12%-148.22%-79.01%-64.83%
Gross Margin----100%100%100%-
Net Margin-----285.69%-1167.76%-5968.5%-
Debt / Equity--0.00x0.01x0.01x0.04x3.09x4.17x
Interest Coverage---22.30x-69.85x---23.92x-
FCF Conversion1.00x0.91x0.93x1.02x0.78x0.90x0.78x0.69x
Revenue Growth------66.67%-80%-100%

Frequently Asked Questions

Growth & Financials

Milestone Pharmaceuticals Inc. (MIST) saw revenue decline by 100.0% over the past year.

Milestone Pharmaceuticals Inc. (MIST) reported a net loss of $58.0M for fiscal year 2024.

Dividend & Returns

Milestone Pharmaceuticals Inc. (MIST) has a return on equity (ROE) of -277.6%. Negative ROE indicates the company is unprofitable.

Milestone Pharmaceuticals Inc. (MIST) had negative free cash flow of $43.2M in fiscal year 2024, likely due to heavy capital investments.

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