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CRISCuris, Inc.
$0.42$82M
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CRIS logoCuris, Inc.(CRIS)Earnings, Financials & Key Ratios

CRIS•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutCuris, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the United States. Its clinical stage drug candidates include Emavusertib, an oral small molecule drug candidate, which is in a Phase 1/2 clinical trial for the treatment of non-hodgkin lymphomas, and acute myeloid leukemia and myelodysplastic syndromes; and CI-8993, a monoclonal antibody designed to antagonize the V-domain Ig suppressor of T cell activation. The company's pipeline also includes Fimepinostat, an oral dual inhibitor of HDAC and PI3K enzymes for the treatment of patients with MYC-altered diffuse large B-cell lymphoma; CA-170, an oral small molecule drug candidate for treating patients with advanced solid tumors and lymphomas; and CA-327, a pre-investigational new drug stage oncology drug candidate. It has collaboration agreement with F. Hoffmann-La Roche Ltd. and Genentech Inc. for the development and commercialization of Erivedge, an orally-administered small molecule hedgehog signaling pathway inhibitor for the treatment of advanced basal cell carcinoma; and with Aurigene Discovery Technologies Limited for the discovery, development, and commercialization of small molecule compounds in the areas of immuno-oncology and precision oncology. Curis, Inc. was incorporated in 2000 and is headquartered in Lexington, Massachusetts.Show more
  • Revenue$9M-13.4%
  • EBITDA-$33M+26.2%
  • Net Income-$8M+82.5%
  • EPS (Diluted)-0.58+91.6%
  • Gross Margin99.52%+0.4%
  • EBITDA Margin-346.64%+14.7%
  • Operating Margin-348.43%+14.7%
  • Net Margin-80.29%+79.8%
  • ROE-138.81%+78.1%

CRIS Key Insights

Curis, Inc. (CRIS) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y profit CAGR of 24.0%
  • ✓High quality earnings: Operating CF exceeds net income

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 5 (bottom 5%)
  • ✗Shares diluted 100.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Expensive at 10.1x book value

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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CRIS Price & Volume

Curis, Inc. (CRIS) stock price & volume — 10-year historical chart

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CRIS Growth Metrics

Curis, Inc. (CRIS) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years1.83%
5 Years-2.71%
3 Years-2.42%
TTM-36.95%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM49.76%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM80.9%

Return on Capital

10 Years-82.35%
5 Years-95.79%
3 Years-137.21%
Last Year-233.94%

CRIS Recent Earnings

Curis, Inc. (CRIS) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)●Beat Revenue 4/12 qtrs (36%)
Q2 2026Latest
May 12, 2026
Metric
Actual
Est
EPS
$1.25-331.0%
$0.29
Rev
—
$2M
Q2 2026
Mar 19, 2026
Metric
Actual
Est
EPS
$0.50-14.7%
$0.44
Rev
$1M-65.0%
$3M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.49+21.0%
$0.62
Rev
$3M+11.0%
$3M
Q3 2025
Aug 5, 2025
Metric
Actual
Est
EPS
$0.68+65.8%
$1.99
Rev
$3M-3.9%
$3M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 12, 2026
$1.25vs $0.29-331.0%
—vs $2M
Q2 2026Mar 19, 2026
$0.50vs $0.44-14.7%
$1Mvs $3M-65.0%
Q4 2025Nov 6, 2025
$0.49vs $0.62+21.0%
$3Mvs $3M+11.0%
Q3 2025Aug 5, 2025
$0.68vs $1.99+65.8%
$3Mvs $3M-3.9%
Based on last 12 quarters of dataView full earnings history →

CRIS Peer Comparison

Curis, Inc. (CRIS) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
TGTX logoTGTXTG Therapeutics, Inc.Direct Competitor8.15B53.2219.2187.32%65.95%87.36%0.40
KPTI logoKPTIKaryopharm Therapeutics Inc.Direct Competitor77.01M9.02-0.500.57%-129.02%
MGNX logoMGNXMacroGenics, Inc.Direct Competitor262.52M4.13-3.500.78%-44.79%-147.8%1.92
IMVT logoIMVTImmunovant, Inc.Direct Competitor7.26B35.34-12.76-68.16%0.00
PRTA logoPRTAProthena Corporation plcDirect Competitor467.51M8.93-1.97-92.84%-260.92%-49.88%0.05
PTCT logoPTCTPTC Therapeutics, Inc.Product Competitor6.55B78.9810.15114.51%-22.58%
FATE logoFATEFate Therapeutics, Inc.Product Competitor243.61M2.09-1.82-51.24%-20.57%-58.89%0.38
AGEN logoAGENAgenus Inc.Product Competitor124.93M3.00-882.3510.37%52.16%

Compare CRIS vs Peers

Curis, Inc. (CRIS) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs TGTX

Most directly comparable listed peer for CRIS.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare CRIS against a more recognizable public peer.

Peer Set

Compare Top 5

vs TGTX, KPTI, MGNX, IMVT

CRIS Income Statement

Curis, Inc. (CRIS) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
9.9M10.43M10M10.84M10.65M10.16M10.02M10.91M9.44M7.06M
Revenue Growth %
31.5%5.35%-4.07%8.31%-1.72%-4.57%-1.37%8.83%-13.43%-36.95%
Cost of Goods Sold
496K563K503K534K533K257K212K98K45K39K
COGS % of Revenue
5.01%5.4%5.03%4.93%5.01%2.53%2.12%0.9%0.48%-
Gross Profit
9.4M▲ 0%
9.87M▲ 4.9%
9.5M▼ 3.7%
10.3M▲ 8.4%
10.12M▼ 1.8%
9.9M▼ 2.1%
9.81M▼ 0.9%
10.81M▲ 10.2%
9.4M▼ 13.1%
7.02M▲ 0%
Gross Margin %
94.99%94.6%94.97%95.07%94.99%97.47%97.88%99.1%99.52%99.45%
Gross Profit Growth %
31.9%4.92%-3.69%8.42%-1.8%-2.09%-0.95%10.18%-13.06%-
Operating Expenses
59.16M39.2M33.86M35.2M52.18M62.92M58.14M55.35M42.34M41.29M
OpEx % of Revenue
597.72%375.89%338.43%324.86%490.01%619.22%580.1%507.44%448.43%-
Selling, General & Admin
25.82M14.79M11.55M12.13M17.3M19.65M18.65M16.79M14.05M15.12M
SG&A % of Revenue
260.84%141.78%115.5%111.96%162.43%193.35%186.04%153.92%148.75%-
Research & Development
33.34M24.41M22.3M23.07M34.88M43.28M39.5M38.56M28.25M26.16M
R&D % of Revenue
336.88%234.11%222.93%212.9%327.58%425.87%394.05%353.52%299.21%-
Other Operating Expenses
-104K000000045K0
Operating Income
-49.76M▲ 0%
-29.33M▲ 41.1%
-24.36M▲ 17.0%
-24.9M▼ 2.2%
-42.06M▼ 68.9%
-53.02M▼ 26.0%
-48.33M▲ 8.8%
-44.54M▲ 7.8%
-32.9M▲ 26.1%
-34.26M▲ 0%
Operating Margin %
-502.73%-281.29%-243.46%-229.79%-395.01%-521.75%-482.21%-408.34%-348.43%-485.12%
Operating Income Growth %
14.26%41.05%16.97%-2.23%-68.95%-26.04%8.84%7.84%26.13%-
EBITDA
-49.52M-29.16M-24.23M-24.75M-41.91M-52.79M-48.08M-44.34M-32.73M-34.14M
EBITDA Margin %
-500.35%-279.59%-242.21%-228.46%-393.53%-519.45%-479.67%-406.48%-346.64%-483.31%
EBITDA Growth %
14.38%41.13%16.89%-2.16%-69.29%-25.96%8.92%7.78%26.18%18.79%
D&A (Non-Cash Add-back)
235K177K125K144K158K233K255K203K169K128K
EBIT
-49.35M-28.65M-27.3M-24.81M-40.96M-51.9M-45.39M-42.77M-5.4M-7.56M
Net Interest Income
-3.45M-3.24M-4.23M-5.03M-4.26M-3.65M919K1.15M-1.87M300K
Interest Income
513K684K614K63K211K1.12M2.94M1.77M316K300K
Interest Expense
3.97M3.93M4.85M5.09M4.47M4.77M2.02M615K2.19M0
Other Income/Expense
-3.56M-3.24M-7.79M-5.01M-3.37M-3.65M919K1.15M25.32M13.1M
Pretax Income
-53.32M▲ 0%
-32.58M▲ 38.9%
-32.14M▲ 1.3%
-29.91M▲ 6.9%
-45.44M▼ 51.9%
-56.67M▼ 24.7%
-47.41M▲ 16.3%
-43.39M▲ 8.5%
-7.58M▲ 82.5%
-21.16M▲ 0%
Pretax Margin %
-538.66%-312.38%-321.28%-276.03%-426.67%-557.69%-473.04%-397.77%-80.29%-299.66%
Income Tax
0000000000
Effective Tax Rate %
0%0%0%0%0%0%0%0%0%0%
Net Income
-53.32M▲ 0%
-32.58M▲ 38.9%
-32.14M▲ 1.3%
-29.91M▲ 6.9%
-45.44M▼ 51.9%
-56.67M▼ 24.7%
-47.41M▲ 16.3%
-43.39M▲ 8.5%
-7.58M▲ 82.5%
-21.16M▲ 0%
Net Margin %
-538.66%-312.38%-321.28%-276.03%-426.67%-557.69%-473.04%-397.77%-80.29%-299.66%
Net Income Growth %
11.74%38.9%1.33%6.95%-51.92%-24.73%16.34%8.49%82.53%49.76%
Net Income (Continuing)
-53.32M-32.58M-32.14M-29.91M-45.44M-56.67M-47.41M-43.39M-7.58M-21.16M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-35.75▲ 0%
-19.67▲ 45.0%
-19.37▲ 1.5%
-12.29▲ 36.6%
-9.92▲ 19.3%
-12.14▼ 22.4%
-8.96▲ 26.2%
-6.88▲ 23.2%
-0.58▲ 91.6%
-0.11▲ 0%
EPS Growth %
21.43%44.98%1.53%36.55%19.28%-22.38%26.19%23.21%91.57%80.9%
EPS (Basic)
-35.75-19.67-19.37-12.29-9.92-12.14-8.96-6.88-0.58-
Diluted Shares Outstanding
1.49M1.66M1.66M2.43M4.58M4.67M5.29M6.31M131.64M193.63M
Basic Shares Outstanding
1.49M1.66M1.66M2.43M4.58M4.67M5.29M6.31M131.64M193.63M
Dividend Payout Ratio
----------

CRIS Balance Sheet

Curis, Inc. (CRIS) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
64.29M27.13M25M172.75M122.38M92.12M60.91M26.39M6.92M15M
Cash & Short-Term Investments
60.23M24.27M20.54M168.49M115.88M85.62M56.33M20M5.06M15M
Cash Only
38.29M23.64M15.43M129.61M40.01M19.66M26.68M20M5.06M15M
Short-Term Investments
21.94M634K5.11M38.88M75.87M65.97M29.65M000
Accounts Receivable
3.07M2.86M3.24M3.04M3.22M2.98M2.79M3.35M00
Days Sales Outstanding
113.32100.25118.36102.51110.5106.86101.75112.06-77.45
Inventory
0-827K00000000
Days Inventory Outstanding
----------
Other Current Assets
00153K003.52M1.78M3.04M1.85M0
Total Non-Current Assets
9.5M10.23M10.1M31.61M39.93M16.73M16.37M14.88M13.05M11.93M
Property, Plant & Equipment
366K267K303K7.24M6.25M5.09M3.49M3.39M1.95M2.94M
Fixed Asset Turnover
27.04x39.06x33.02x1.50x1.70x2.00x2.87x3.21x4.84x2.86x
Goodwill
8.98M8.98M8.98M8.98M8.98M8.98M8.98M8.98M8.98M8.98M
Intangible Assets
0000000000
Long-Term Investments
153K153K014.56M23.96M00544K0544K
Other Non-Current Assets
156K982K819K819K726K2.66M3.9M1.96M2.12M-544K
Total Assets
73.8M▲ 0%
37.37M▼ 49.4%
35.11M▼ 6.0%
204.36M▲ 482.1%
162.3M▼ 20.6%
108.85M▼ 32.9%
77.28M▼ 29.0%
41.27M▼ 46.6%
19.97M▼ 51.6%
29.69M▲ 0%
Asset Turnover
0.13x0.28x0.28x0.05x0.07x0.09x0.13x0.26x0.47x0.27x
Asset Growth %
27.78%-49.37%-6.04%482.1%-20.58%-32.93%-29%-46.6%-51.62%-153.06%
Total Current Liabilities
14.1M6.38M6.54M10.08M13.44M10.01M22.02M19.03M14.08M14.97M
Accounts Payable
5.42M2.91M4.46M4.17M6.42M3.19M3.17M3.02M5.61M6.74M
Days Payables Outstanding
3.99K1.89K3.24K2.85K4.39K4.53K5.46K11.26K45.52K48.89K
Short-Term Debt
5.89M6.88M0557K000001.23M
Deferred Revenue (Current)
0-6.87M00000000
Other Current Liabilities
606K683K1.41M2.64M3.26M08.5M7.56M07M
Current Ratio
4.56x4.25x3.82x17.14x9.11x9.20x2.77x1.39x0.49x1.00x
Quick Ratio
4.56x4.38x3.82x17.14x9.11x9.20x2.77x1.39x0.49x1.00x
Cash Conversion Cycle
----------48.81K
Total Non-Current Liabilities
35.7M35.48M62.48M63.61M58.16M52.28M35.59M28.24M428K2M
Long-Term Debt
35.67M28.6M0334K000000
Capital Lease Obligations
0005.04M4.36M2.8M1.49M1.62M428K2.32M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
34K11K62.48M58.23M53.8M49.48M34.1M26.62M01.9M
Total Liabilities
49.8M41.86M69.02M73.69M71.59M62.3M57.61M47.26M14.5M16.98M
Total Debt
41.55M35.48M166K7.66M5.04M3.94M2.79M2.95M1.62M1.34M
Net Debt
3.27M11.85M-15.26M-121.95M-34.97M-15.72M-23.89M-17.04M-3.44M-13.66M
Debt / Equity
1.73x--0.06x0.06x0.08x0.14x-0.30x0.11x
Debt / EBITDA
----------0.04x
Net Debt / EBITDA
---------0.40x
Interest Coverage
-12.44x-7.30x-5.63x-4.87x-9.16x-10.88x-22.48x-69.55x-2.47x-
Total Equity
23.99M▲ 0%
-4.5M▼ 118.7%
-33.91M▼ 654.2%
130.67M▲ 485.3%
90.71M▼ 30.6%
46.55M▼ 48.7%
19.67M▼ 57.7%
-6M▼ 130.5%
5.46M▲ 191.1%
12.71M▲ 0%
Equity Growth %
-18.02%-118.74%-654.25%485.33%-30.58%-48.68%-57.75%-130.49%191.06%-1500.07%
Book Value per Share
16.09-2.72-20.4453.7019.819.973.72-0.950.040.07
Total Shareholders' Equity
23.99M-4.5M-33.91M130.67M90.71M46.55M19.67M-6M5.46M12.71M
Common Stock
1.65M332K332K915K916K48K59K85K129K400K
Retained Earnings
-952.26M-984.84M-1.02B-1.05B-1.09B-1.15B-1.2B-1.24B-1.25B-1.27B
Treasury Stock
-1.52M000000000
Accumulated OCI
-2K00-3K-109K-186K229K000
Minority Interest
0000000000

CRIS Cash Flow Statement

Curis, Inc. (CRIS) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-48.35M-30.07M-26.2M-25.74M-37.62M-54.34M-38.43M-39.56M-27.2M-28.95M
Operating CF Margin %
-488.53%-288.31%-261.95%-237.55%-353.26%-534.71%-383.46%-362.7%-288.05%-
Operating CF Growth %
-35.03%37.82%12.84%1.78%-46.16%-44.44%29.27%-2.94%31.25%41.34%
Net Income
-53.32M-32.58M-32.14M-29.91M-45.44M-56.67M-47.41M-43.39M-7.58M-21.16M
Depreciation & Amortization
235K177K125K144K158K1.39M255K187K169K118K
Stock-Based Compensation
5.36M3.94M2.66M2.7M5.28M06M5.93M4.02M2.85M
Deferred Taxes
07K024K1.4M00000
Other Non-Cash Items
91K-112K4.71M255K-26K7.76M-55K1.43M-25.56M-10.79M
Working Capital Changes
-723K-1.5M-1.56M1.05M1M-6.82M2.78M-3.72M1.75M30K
Change in Receivables
-614K209K-380K201K-181K249K181K-555K-1.03M-2.07M
Change in Inventory
-49.92M1.87M00000000
Change in Payables
-376K-1.87M60K1M4.96M-3.88M3.34M-2.08M2.55M2.78M
Cash from Investing
-3.63M21.37M-4.46M-49.05M-47.9M33.02M37.79M29.44M2.5M2.5M
Capital Expenditures
-188K-85K-41K-677K0-416K0000
CapEx % of Revenue
1.9%0.82%0.41%6.25%-4.09%---0%
Acquisitions
188K85K00000000
Investments
----------
Other Investing
-188K-85K0000002.5M2.5M
Cash from Financing
64.23M-5.96M23.27M188.81M-4.17M867K7.58M3.44M9.77M21.17M
Debt Issued (Net)
21.74M-6.1M23.2M891K0-4.97M0-8.59M-5.59M-3.12M
Equity Issued (Net)
41.55M068K193.22M300K5.84M14.12M12.02M15.35M24.29M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
946K143K0-5.3M-4.47M0-6.54M000
Net Change in Cash
12.25M▲ 0%
-14.65M▼ 219.6%
-8.05M▲ 45.0%
114.03M▲ 1516.0%
-89.69M▼ 178.7%
-20.36M▲ 77.3%
6.93M▲ 134.1%
-6.68M▼ 196.4%
-14.94M▼ 123.5%
-5.28M▲ 0%
Free Cash Flow
-48.54M▲ 0%
-30.15M▲ 37.9%
-26.25M▲ 12.9%
-26.42M▼ 0.6%
-37.62M▼ 42.4%
-54.75M▼ 45.5%
-38.43M▲ 29.8%
-39.56M▼ 2.9%
-27.2M▲ 31.2%
-28.95M▲ 0%
FCF Margin %
-490.43%-289.13%-262.36%-243.8%-353.26%-538.8%-383.46%-362.7%-288.05%-409.88%
FCF Growth %
-34.32%37.89%12.95%-0.65%-42.41%-45.55%29.8%-2.94%31.25%13.8%
FCF per Share
-32.55-18.21-15.82-10.86-8.22-11.73-7.26-6.27-0.21-0.15
FCF Conversion (FCF/Net Income)
0.91x0.92x0.82x0.86x0.83x0.96x0.81x0.91x3.59x1.37x
Interest Paid
0000000000
Taxes Paid
0000000000

CRIS Key Ratios

Curis, Inc. (CRIS) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
-200.22%-334.15%--61.82%-41.05%-82.58%-143.19%-634.71%-138.81%805.67%
Return on Invested Capital (ROIC)
-148.25%-127.12%---97.89%-91.87%-272.36%--241.71%
Gross Margin
94.99%94.6%94.97%95.07%94.99%97.47%97.88%99.1%99.52%99.45%
Net Margin
-538.66%-312.38%-321.28%-276.03%-426.67%-557.69%-473.04%-397.77%-80.29%-299.66%
Debt / Equity
1.73x--0.06x0.06x0.08x0.14x-0.30x0.11x
Interest Coverage
-12.44x-7.30x-5.63x-4.87x-9.16x-10.88x-22.48x-69.55x-2.47x-
FCF Conversion
0.91x0.92x0.82x0.86x0.83x0.96x0.81x0.91x3.59x1.37x
Revenue Growth
31.5%5.35%-4.07%8.31%-1.72%-4.57%-1.37%8.83%-13.43%-36.95%
Related:CRIS Dividend History·CRIS Revenue History·CRIS Price History·CRIS P/E History·CRIS Financial Ratios·CRIS Institutional Holders

CRIS SEC Filings & Documents

Curis, Inc. (CRIS) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 22, 2026·SEC

Material company update

May 12, 2026·SEC

Material company update

May 1, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 24, 2026·SEC

FY 2025

Mar 31, 2025·SEC

FY 2024

Feb 8, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 13, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 5, 2025·SEC

CRIS Frequently Asked Questions

Curis, Inc. (CRIS) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Curis, Inc. (CRIS) reported $7.1M in revenue for fiscal year 2025. This represents a 120% increase from $3.2M in 1999.

Curis, Inc. (CRIS) saw revenue decline by 13.4% over the past year.

Curis, Inc. (CRIS) reported a net loss of $21.2M for fiscal year 2025.

Dividend & Returns

Curis, Inc. (CRIS) has a return on equity (ROE) of -138.8%. Negative ROE indicates the company is unprofitable.

Curis, Inc. (CRIS) had negative free cash flow of $28.9M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in CRIS back in 1999?

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