← Back to Screener
US Stock Screener
HomeScreensNewsWatchlist
...

Agios Pharmaceuticals, Inc. (AGIO) 10-Year Financial Performance & Capital Metrics

AGIO • • Industrial / General
HealthcareBiotechnologyMetabolic & Liver DiseasesHematologic Oncology
AboutAgios Pharmaceuticals, Inc., a biopharmaceutical company, engages in the discovery and development of medicines in the field of cellular metabolism and adjacent areas of biology. The company offers PYRUKYND (mitapivat) an activator of both wild-type and a variety of mutant pyruvate kinase, PK, enzymes for the treatment of hemolytic anemias; and AG-946 that is in Phase I clinical study for treating hemolytic anemias and other indications. Agios Pharmaceuticals, Inc. was incorporated in 2007 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue $36M +36.1%
  • EBITDA -$420M -9.2%
  • Net Income $674M +291.4%
  • EPS (Diluted) 11.64 +283.9%
  • Gross Margin 88.59% +37.2%
  • EBITDA Margin -1150.98% +19.8%
  • Operating Margin -1166.47% +20.1%
  • Net Margin 1845.92% +240.6%
  • ROE 57.29% +255.5%
  • ROIC -27.57% +13.5%
  • Debt/Equity 0.04 -58.3%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Trading at only 1.1x book value

✗Weaknesses

  • ✗Weak 3Y average ROE of 0.4%
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 14 (bottom 14%)
  • ✗Sales declining 20.9% over 5 years
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

Loading chart...

Growth Metrics

Revenue CAGR

10Y-5.66%
5Y-20.91%
3Y-
TTM36.26%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-25.12%
TTM-159.51%

EPS CAGR

10Y-
5Y-
3Y-
TTM-161.18%

ROCE

10Y Avg-42.87%
5Y Avg-36.42%
3Y Avg-34.5%
Latest-34.74%

Peer Comparison

Hematologic Oncology
Select Columns
Size & Scale
Valuation
Per Share
Growth
Profitability
Quality & Returns
Safety & Leverage
TTM Growth
Famous Investor Metrics
Dividends
Latest Quarter
Momentum & Returns
Total Return (DRIP)
Technical
Volume & Trading
Shares & Dilution
Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
INCYIncyte Corporation20.8B105.95706.3314.76%24.69%25.55%1.2%0.01
TGTXTG Therapeutics, Inc.4.69B29.54196.9340.8%13.31%21.87%1.14
AGIOAgios Pharmaceuticals, Inc.1.68B28.732.4736.07%-8.96%-31.24%0.04
CLRBCellectar Biosciences, Inc.15.9M3.75-0.09-200.99%0.03
CASICASI Pharmaceuticals, Inc.20.96M1.02-0.40-15.77%-183.93%-301.8%11.96
VORVor Biopharma Inc.323.62M14.77-0.43-94.52%0.33
FATEFate Therapeutics, Inc.124.58M1.08-0.66-78.55%-21.87%-66.69%0.27
KPTIKaryopharm Therapeutics Inc.131.65M7.19-0.76-0.55%-87.43%

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+59.12M69.89M43.01M94.39M117.91M0014.24M26.82M36.5M
Revenue Growth %-0.1%0.18%-0.38%1.19%0.25%-1%--0.88%0.36%
Cost of Goods Sold+141.83M220.16M292.68M1.4M1.32M18.77M18.78M1.7M9.5M4.17M
COGS % of Revenue2.4%3.15%6.8%0.01%0.01%--0.12%0.35%0.11%
Gross Profit+-82.71M-150.27M-249.67M92.99M116.59M-18.77M-18.78M12.54M17.32M32.33M
Gross Margin %-1.4%-2.15%-5.8%0.99%0.99%--0.88%0.65%0.89%
Gross Profit Growth %-1.36%-0.82%-0.66%1.37%0.25%-1.16%-0%1.67%0.38%0.87%
Operating Expenses+177.82M270.88M363.81M455.47M542.93M317.14M359.64M401.58M408.81M458.07M
OpEx % of Revenue3.01%3.88%8.46%4.83%4.6%--28.2%15.24%12.55%
Selling, General & Admin35.99M50.71M71.12M114.14M132.03M106.12M121.44M121.67M119.9M156.78M
SG&A % of Revenue0.61%0.73%1.65%1.21%1.12%--8.54%4.47%4.3%
Research & Development141.83M220.16M292.68M341.32M410.89M211.02M256.97M279.91M288.9M301.29M
R&D % of Revenue2.4%3.15%6.8%3.62%3.48%--19.66%10.77%8.25%
Other Operating Expenses000000-18.78M000
Operating Income+-118.7M-200.99M-320.79M-362.48M-426.33M-335.92M-378.42M-389.05M-391.49M-425.74M
Operating Margin %-2.01%-2.88%-7.46%-3.84%-3.62%---27.32%-14.6%-11.66%
Operating Income Growth %-1.19%-0.69%-0.6%-0.13%-0.18%0.21%-0.13%-0.03%-0.01%-0.09%
EBITDA+-115.36M-195.28M-314.36M-355.31M-409.71M-317.14M-359.64M-380.48M-384.86M-420.08M
EBITDA Margin %-1.95%-2.79%-7.31%-3.76%-3.47%---26.72%-14.35%-11.51%
EBITDA Growth %-1.19%-0.69%-0.61%-0.13%-0.15%0.23%-0.13%-0.06%-0.01%-0.09%
D&A (Non-Cash Add-back)3.34M5.71M6.43M7.17M16.62M18.77M18.78M8.56M6.62M5.65M
EBIT-118.7M-200.99M-320.79M-346.03M-411.47M-329.31M-356.51M-389.05M-391.49M-425.74M
Net Interest Income+968K2.51M6.12M16.45M14.86M-11.22M836K12.79M33.34M48.08M
Interest Income968K2.51M6.12M16.45M14.86M6.61M836K12.79M33.34M48.08M
Interest Expense0000017.83M0000
Other Income/Expense968K2.51M6.12M16.45M14.86M6.61M21.91M157.25M39.4M1.14B
Pretax Income+-117.73M-198.47M-314.67M-346.03M-411.47M-329.31M-356.51M-231.8M-352.09M717.97M
Pretax Margin %-1.99%-2.84%-7.32%-3.67%-3.49%---16.28%-13.13%19.67%
Income Tax+-426K0000000044.24M
Effective Tax Rate %1%1%1%1%1%0.99%-4.5%1%1%0.94%
Net Income+-117.73M-198.47M-314.67M-346.03M-411.47M-327.37M1.6B-231.8M-352.09M673.73M
Net Margin %-1.99%-2.84%-7.32%-3.67%-3.49%---16.28%-13.13%18.46%
Net Income Growth %-1.2%-0.69%-0.59%-0.1%-0.19%0.2%5.9%-1.14%-0.52%2.91%
Net Income (Continuing)-117.73M-198.47M-314.67M-346.03M-411.47M-329.31M-356.51M-231.8M-352.09M673.73M
Discontinued Operations000001.94M1.96B000
Minority Interest0000000000
EPS (Diluted)+-3.15-5.07-6.75-6.03-6.61-4.74-6.36-4.23-6.3311.64
EPS Growth %-0.98%-0.61%-0.33%0.11%-0.1%0.28%-0.34%0.33%-0.5%2.84%
EPS (Basic)-3.15-5.07-6.75-6.03-6.61-4.74-6.36-4.23-6.3311.86
Diluted Shares Outstanding37.43M39.13M46.59M57.42M59.99M69M60.45M54.79M55.65M57.89M
Basic Shares Outstanding37.43M39.13M46.59M57.42M59.99M69M60.45M54.79M55.65M56.81M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+337.33M559.89M445.26M613.78M611.7M636.68M1.06B832.77M833.84M965.6M
Cash & Short-Term Investments375.91M573.56M567.75M805.42M564.88M572.93M1.02B783.12M776.93M893.71M
Cash Only375.91M573.56M567.75M805.42M80.93M127.44M203.13M139.26M88.2M76.25M
Short-Term Investments0000483.95M445.49M816.89M643.86M688.72M817.46M
Accounts Receivable11.6M8.31M3.67M10.44M15.32M04.38M2.21M2.81M4.11M
Days Sales Outstanding71.6143.4231.1440.3847.42--56.5438.2441.09
Inventory-58.91M-32.25M-143.81M869K7.33M008.49M19.08M27.62M
Days Inventory Outstanding---227.052.03K--1.82K732.612.42K
Other Current Assets00017.17M063.75M038.95M35.02M40.16M
Total Non-Current Assets+82.74M59.2M169.14M244.68M279.04M216.27M373.5M405.95M103.28M697.6M
Property, Plant & Equipment23.22M25.34M24.43M24.32M126.11M116.07M104.23M88.12M69.79M54.55M
Fixed Asset Turnover2.55x2.76x1.76x3.88x0.94x--0.16x0.38x0.67x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments58.91M32.25M143.81M220.12M152.93M97.61M266.38M313.87M29.43M638.32M
Other Non-Current Assets611K1.61M891K238K02.6M2.9M3.96M4.06M4.72M
Total Assets+420.06M619.09M614.4M858.46M890.74M852.95M1.44B1.24B937.12M1.66B
Asset Turnover0.14x0.11x0.07x0.11x0.13x--0.01x0.03x0.02x
Asset Growth %-0.15%0.47%-0.01%0.4%0.04%-0.04%0.69%-0.14%-0.24%0.77%
Total Current Liabilities+52.89M88.43M94.94M93.5M92.89M94.39M59.83M62.63M67.95M81.16M
Accounts Payable14.75M17.11M22.77M17.88M21.9M17.72M16.7M18.62M9.78M16.64M
Days Payables Outstanding37.9528.3628.394.67K6.07K344.62324.633.99K375.61.46K
Short-Term Debt000007.41M0000
Deferred Revenue (Current)1000K1000K1000K1000K1000K00000
Other Current Liabilities11.47M24.32M18.64M22.07M18.98M48.91M19.82M12.24M23.23M46.86M
Current Ratio6.38x6.33x4.69x6.56x6.59x6.74x17.79x13.30x12.27x11.90x
Quick Ratio7.49x6.70x6.20x6.55x6.51x6.74x17.79x13.16x11.99x11.56x
Cash Conversion Cycle----4.4K-3.99K---2.11K395.251K
Total Non-Current Liabilities+22.06M172.07M143.95M77.42M157.33M359.06M85.94M75.28M58.14M41.09M
Long-Term Debt0000000000
Capital Lease Obligations0000106.75M97.79M85.94M72M56.99M40.21M
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities17.36M17.77M18.16M17.61M0261.27M03.28M1.16M880K
Total Liabilities74.95M260.5M238.89M170.92M250.21M453.45M145.76M137.9M126.1M122.24M
Total Debt+0000113.66M105.2M97.09M85.66M72M56.99M
Net Debt-375.91M-573.56M-567.75M-805.42M32.73M-22.24M-106.03M-53.6M-16.21M-19.26M
Debt / Equity----0.18x0.26x0.08x0.08x0.09x0.04x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage------18.84x----
Total Equity+345.12M358.59M375.5M687.54M640.53M399.5M1.29B1.1B811.02M1.54B
Equity Growth %-0.19%0.04%0.05%0.83%-0.07%-0.38%2.23%-0.15%-0.26%0.9%
Book Value per Share9.229.168.0611.9710.685.7921.3720.0914.5726.62
Total Shareholders' Equity345.12M358.59M375.5M687.54M640.53M399.5M1.29B1.1B811.02M1.54B
Common Stock38K42K49K58K68K69K71K71K72K73K
Retained Earnings-284.68M-483.15M-798.06M-1.1B-1.52B-1.84B-238.76M-470.56M-822.65M-148.92M
Treasury Stock000000-802.49M-802.49M-802.49M-802.49M
Accumulated OCI-318K-313K-1.39M-2.17M202K105K-1.2M-12.54M-441K-1.52M
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-76.95M38.56M-285.23M-304.42M-370.62M-290.76M-407.32M-309.48M-296.06M-389.84M
Operating CF Margin %-1.3%0.55%-6.63%-3.23%-3.14%---21.73%-11.04%-10.68%
Operating CF Growth %-0.3%1.5%-8.4%-0.07%-0.22%0.22%-0.4%0.24%0.04%-0.32%
Net Income-117.73M-198.47M-314.67M-346.03M-411.47M-329.31M-356.51M-231.8M-352.09M673.73M
Depreciation & Amortization3.34M5.71M6.43M7.17M8.09M18.77M9.24M8.56M6.62M5.65M
Stock-Based Compensation31.96M42.09M47.81M73.36M72.37M053.51M49.3M44.77M42.85M
Deferred Taxes0000-2.14M00000
Other Non-Cash Items572K773K29K-3.82M8.53M17.81M-76.74M-119.1M23.69M-1.09B
Working Capital Changes4.91M188.47M-24.83M-35.1M-46M1.97M-36.82M-16.43M-19.06M-19.77M
Change in Receivables-1.73M3.34M1.22M-6.1M-3.62M0-4.38M-2.21M-604K-1.3M
Change in Inventory-3.17M14.43M-2.08M-869K-6.46M-7.37M0-8.49M-10.58M-8.54M
Change in Payables4.21M3.5M5.33M-5.49M3.72M3.33M1.86M3.44M-8.73M6.6M
Cash from Investing+128.31M-119.35M-57.91M-273.82M91.44M75.75M1.25B243.26M239.57M363.44M
Capital Expenditures-20.16M-9.91M-4.63M-6.99M-12.17M-14.11M-5.74M-4.88M-999K-1.69M
CapEx % of Revenue0.34%0.14%0.11%0.07%0.1%--0.34%0.04%0.05%
Acquisitions----------
Investments----------
Other Investing148.47M-109.44M-53.28M-266.84M103.47M-803K1.8B0-16.18M1.09B
Cash from Financing+6.37M169.78M285.11M546.02M289.61M261.52M-765.77M2.35M5.43M14.44M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing6.37M7.63M14.86M29.82M12.52M250.54M37.3M000
Net Change in Cash----------
Free Cash Flow+-97.11M28.65M-289.86M-311.41M-382.79M-304.87M-413.06M-314.36M-297.06M-391.53M
FCF Margin %-1.64%0.41%-6.74%-3.3%-3.25%---22.08%-11.07%-10.73%
FCF Growth %-0.58%1.29%-11.12%-0.07%-0.23%0.2%-0.35%0.24%0.06%-0.32%
FCF per Share-2.590.73-6.22-5.42-6.38-4.42-6.83-5.74-5.34-6.76
FCF Conversion (FCF/Net Income)0.65x-0.19x0.91x0.88x0.90x0.89x-0.25x1.34x0.84x-0.58x
Interest Paid0000000000
Taxes Paid00000016.08M01.57M43.15M

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-30.6%-56.41%-85.73%-65.1%-61.97%-62.95%189.74%-19.38%-36.83%57.29%
Return on Invested Capital (ROIC)-46.91%----115.15%-47.96%-36.31%-26.13%-31.88%-27.57%
Gross Margin-139.9%-215%-580.48%98.52%98.88%--88.03%64.57%88.59%
Net Margin-199.14%-283.97%-731.6%-366.61%-348.97%---1627.82%-1312.63%1845.92%
Debt / Equity----0.18x0.26x0.08x0.08x0.09x0.04x
Interest Coverage------18.84x----
FCF Conversion0.65x-0.19x0.91x0.88x0.90x0.89x-0.25x1.34x0.84x-0.58x
Revenue Growth-9.55%18.22%-38.46%119.45%24.92%-100%--88.36%36.07%

Revenue by Segment

201820192020202220232024
Product13.84M59.85M121.09M11.74M26.82M36.5M
Product Growth-332.42%102.32%-90.30%128.48%36.07%
Royalty7.21M10.54M10.26M2.5M--
Royalty Growth-46.11%-2.66%-75.64%--
Collaboration Revenue, Related Party60.66M39.26M68.27M---
Collaboration Revenue, Related Party Growth--35.28%73.92%---
Research Services-35.95M64.35M---
Research Services Growth--78.97%---
Commercialization Activity-3.3M3.93M---
Commercialization Activity Growth--18.89%---
Development Activities------
Development Activities Growth------
Committee Participation------
Committee Participation Growth------
Collaboration Revenue, Other12.67M8.26M----
Collaboration Revenue, Other Growth--34.79%----

Frequently Asked Questions

Valuation & Price

Agios Pharmaceuticals, Inc. (AGIO) has a price-to-earnings (P/E) ratio of 2.5x. This may indicate the stock is undervalued or faces growth challenges.

Growth & Financials

Agios Pharmaceuticals, Inc. (AGIO) reported $44.8M in revenue for fiscal year 2024. This represents a 105% increase from $21.8M in 2011.

Agios Pharmaceuticals, Inc. (AGIO) grew revenue by 36.1% over the past year. This is strong growth.

Agios Pharmaceuticals, Inc. (AGIO) reported a net loss of $401.3M for fiscal year 2024.

Dividend & Returns

Agios Pharmaceuticals, Inc. (AGIO) has a return on equity (ROE) of 57.3%. This is excellent, indicating efficient use of shareholder capital.

Agios Pharmaceuticals, Inc. (AGIO) had negative free cash flow of $414.1M in fiscal year 2024, likely due to heavy capital investments.

VCP Scanner

Find stocks. Verify deeply. Act with conviction.

Patterns find ideas. Fundamentals build conviction.

Data updated daily

Quick Links

  • Home
  • Screens
  • Valuation
  • Compare
  • Total Return
  • News
  • Insights
  • Methodology
  • How It Works
  • Profile

Popular Screens

  • VCP Hot
  • VCP Warm
  • Value Screens
  • Growth Screens
  • Momentum Screens
  • Technical Screens
  • Quality Screens

Community

  • Twitter
  • Get Early Access
© 2026 VCP Scanner. All rights reserved.
Made with ❤️ for investors
Not financial advice. Do your own research.