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FOLDAmicus Therapeutics, Inc.
$14.49$4.5B
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FOLD logoAmicus Therapeutics, Inc.(FOLD)Earnings, Financials & Key Ratios

FOLD•NASDAQ
Price updated May 18, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryCommercial Rare Disease Biopharma
AboutAmicus Therapeutics, Inc., a biotechnology company, focuses on discovering, developing, and delivering medicines for rare diseases. Its commercial product and product candidates include Galafold, an oral precision medicine for the treatment of adults with a confirmed diagnosis of Fabry disease and an amenable galactosidase alpha gene variant based on in vitro assay data. It also develops AT-GAA, a novel treatment paradigm for Pompe disease; enzyme replacement therapies for Pompe diseases; CLN3, which is in Phase 1/2 clinical study to evaluate the safety and efficacy of a single intrathecal administration of an AAV serotype AT-GTX-502 gene therapy in patients with CLN3; and CDKL5, a gene on the X-chromosome encoding the CDKL5 protein that regulates the expression of essential proteins for normal brain development. The company has collaboration and license agreements with Nationwide Children's Hospital; University of Pennsylvania; and GlaxoSmithKline. Amicus Therapeutics, Inc. was incorporated in 2002 and is headquartered in Philadelphia, Pennsylvania.Show more
  • Revenue$634M+20.0%
  • EBITDA$42M+25.5%
  • Net Income-$27M+51.7%
  • EPS (Diluted)-0.09+51.2%
  • Gross Margin87.32%-2.9%
  • EBITDA Margin6.61%+4.6%
  • Operating Margin5.44%+15.5%
  • Net Margin-4.27%+59.8%
  • ROE-11.58%+63.5%

FOLD Key Insights

Amicus Therapeutics, Inc. (FOLD) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y profit CAGR of 37.2%
  • ✓Momentum leader: RS Rating 83 (top 17%)
  • ✓Strong 5Y sales CAGR of 19.4%
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Expensive at 16.3x book value

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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FOLD Price & Volume

Amicus Therapeutics, Inc. (FOLD) stock price & volume — 10-year historical chart

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FOLD Growth Metrics

Amicus Therapeutics, Inc. (FOLD) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years19.44%
3 Years24.43%
TTM20.05%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM51.68%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM50.86%

Return on Capital

10 Years-27.11%
5 Years-12.52%
3 Years-1.27%
Last Year5.12%

FOLD Recent Earnings

Amicus Therapeutics, Inc. (FOLD) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 6/12 qtrs (50%)
Q1 2026Latest
Feb 20, 2026
Metric
Actual
Est
EPS
$0.01-86.0%
$0.07
Rev
$185M+2.6%
$181M
Q4 2025
Nov 4, 2025
Metric
Actual
Est
EPS
$0.17+41.7%
$0.12
Rev
$169M-8.6%
$185M
Q3 2025
Jul 31, 2025
Metric
Actual
Est
EPS
$0.01-50.0%
$0.02
Rev
$155M-6.4%
$165M
Q2 2025
May 1, 2025
Metric
Actual
Est
EPS
$0.03-62.5%
$0.08
Rev
$125M-15.1%
$147M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q1 2026LatestFeb 20, 2026
$0.01vs $0.07-86.0%
$185Mvs $181M+2.6%
Q4 2025Nov 4, 2025
$0.17vs $0.12+41.7%
$169Mvs $185M-8.6%
Q3 2025Jul 31, 2025
$0.01vs $0.02-50.0%
$155Mvs $165M-6.4%
Q2 2025May 1, 2025
$0.03vs $0.08-62.5%
$125Mvs $147M-15.1%
Based on last 12 quarters of dataView full earnings history →

FOLD Peer Comparison

Amicus Therapeutics, Inc. (FOLD) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
RARE logoRAREUltragenyx Pharmaceutical Inc.Direct Competitor2.7B27.44-4.7120.13%-91.03%-6.08%
SRPT logoSRPTSarepta Therapeutics, Inc.Direct Competitor1.85B17.53-2.4615.58%2.98%4.89%0.91
BMRN logoBMRNBioMarin Pharmaceutical Inc.Direct Competitor10.52B54.6930.3812.87%8.29%4.41%0.11
IONS logoIONSIonis Pharmaceuticals, Inc.Direct Competitor12.25B74.12-31.1433.87%-30.87%-58.57%5.35
KRYS logoKRYSKrystal Biotech, Inc.Product Competitor10.26B348.0650.8933.94%53.92%19.25%0.01
ACAD logoACADACADIA Pharmaceuticals Inc.Product Competitor3.7B21.629.4411.87%34.3%35.65%0.04
PTCT logoPTCTPTC Therapeutics, Inc.Product Competitor6.55B78.9810.15114.51%-22.58%
LGND logoLGNDLigand Pharmaceuticals IncorporatedProduct Competitor5.51B274.8844.8460.4%55.95%16.19%0.44

Compare FOLD vs Peers

Amicus Therapeutics, Inc. (FOLD) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RARE

Most directly comparable listed peer for FOLD.

Scale Benchmark

vs IQV

Larger-name benchmark to compare FOLD against a more recognizable public peer.

Peer Set

Compare Top 5

vs RARE, SRPT, BMRN, IONS

FOLD Income Statement

Amicus Therapeutics, Inc. (FOLD) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue
36.93M91.25M182.24M260.89M305.51M329.23M399.36M528.29M634.21M
Revenue Growth %
644.86%147.08%99.72%43.16%17.11%7.76%21.3%32.29%20.05%
Cost of Goods Sold
6.24M14.4M21.96M31.04M34.47M38.6M37.33M52.94M80.39M
COGS % of Revenue
16.89%15.79%12.05%11.9%11.28%11.72%9.35%10.02%12.68%
Gross Profit
30.69M▲ 0%
76.84M▲ 150.3%
160.27M▲ 108.6%
229.84M▲ 43.4%
271.05M▲ 17.9%
290.63M▲ 7.2%
362.03M▲ 24.6%
475.35M▲ 31.3%
553.82M▲ 16.5%
Gross Margin %
83.11%84.21%87.95%88.1%88.72%88.28%90.65%89.98%87.32%
Gross Profit Growth %
644.1%150.35%108.58%43.41%17.93%7.23%24.57%31.3%16.51%
Operating Expenses
241.57M402.32M464.31M476.84M477.48M502.75M439.24M450.48M519.33M
OpEx % of Revenue
654.14%440.92%254.78%182.78%156.29%152.7%109.99%85.27%81.89%
Selling, General & Admin
88.67M127.2M169.86M156.41M192.71M213.04M275.27M323.38M383.49M
SG&A % of Revenue
240.11%139.4%93.21%59.95%63.08%64.71%68.93%61.21%60.47%
Research & Development
149.31M270.9M286.38M308.44M272.05M276.68M152.38M109.36M135.84M
R&D % of Revenue
404.31%296.9%157.15%118.23%89.05%84.04%38.16%20.7%21.42%
Other Operating Expenses
6.01M-5.63M8.07M11.99M12.72M13.04M11.59M17.73M0
Operating Income
-441.99M▲ 0%
-328.78M▲ 25.6%
-304.04M▲ 7.5%
-247M▲ 18.8%
-206.43M▲ 16.4%
-212.12M▼ 2.8%
-77.21M▲ 63.6%
24.88M▲ 132.2%
34.49M▲ 38.7%
Operating Margin %
-1196.82%-360.32%-166.84%-94.68%-67.57%-64.43%-19.33%4.71%5.44%
Operating Income Growth %
-143%25.61%7.52%18.76%16.42%-2.75%63.6%132.22%38.65%
EBITDA
-438.39M-324.56M-299.26M-238.15M-200.22M-206.78M-69.34M33.42M41.95M
EBITDA Margin %
-1187.09%-355.7%-164.22%-91.29%-65.54%-62.81%-17.36%6.33%6.61%
EBITDA Growth %
-145.39%25.97%7.79%20.42%15.93%-3.27%66.47%148.2%25.52%
D&A (Non-Cash Add-back)
3.59M4.22M4.78M8.85M6.21M5.34M7.87M8.55M7.46M
EBIT
-431.88M-326.69M-337.04M-251.83M-209.08M-204.92M-99.95M20.84M46.35M
Net Interest Income
-13.14M-11.94M-8.62M-19.2M-31.96M-34.09M-43.07M-44.19M-42.84M
Interest Income
4.1M10.46M10.25M3.23M509K3.02M7.08M5.41M3.32M
Interest Expense
17.24M22.4M18.87M22.43M32.47M37.12M50.15M49.6M46.16M
Other Income/Expense
-7.14M-23.61M-51.87M-27.26M-35.12M-29.92M-72.89M-53.63M-34.3M
Pretax Income
-449.12M▲ 0%
-349.09M▲ 22.3%
-355.91M▼ 2.0%
-274.25M▲ 22.9%
-241.55M▲ 11.9%
-242.04M▼ 0.2%
-150.1M▲ 38.0%
-28.76M▲ 80.8%
191K▲ 100.7%
Pretax Margin %
-1216.14%-382.58%-195.3%-105.12%-79.06%-73.52%-37.59%-5.44%0.03%
Income Tax
-165.12M-94K478K2.6M8.91M-5.47M1.48M27.35M27.3M
Effective Tax Rate %
36.76%0.03%-0.13%-0.95%-3.69%2.26%-0.99%-95.11%14293.72%
Net Income
-284M▲ 0%
-349M▼ 22.9%
-356.39M▼ 2.1%
-276.85M▲ 22.3%
-250.46M▲ 9.5%
-236.57M▲ 5.5%
-151.58M▲ 35.9%
-56.11M▲ 63.0%
-27.11M▲ 51.7%
Net Margin %
-769.03%-382.48%-195.56%-106.12%-81.98%-71.85%-37.96%-10.62%-4.27%
Net Income Growth %
-41.97%-22.88%-2.12%22.32%9.53%5.55%35.92%62.99%51.68%
Net Income (Continuing)
-284M-349M-356.39M-276.85M-250.46M-236.57M-151.58M-56.11M-27.11M
Discontinued Operations
000000000
Minority Interest
000000000
EPS (Diluted)
-1.85▲ 0%
-1.88▼ 1.6%
-1.48▲ 21.3%
-1.07▲ 27.7%
-0.92▲ 14.0%
-0.82▲ 10.9%
-0.51▲ 37.8%
-0.18▲ 64.7%
-0.09▲ 51.2%
EPS Growth %
-24.16%-1.62%21.28%27.7%14.02%10.87%37.8%64.71%51.17%
EPS (Basic)
-1.85-1.88-1.48-1.07-0.92-0.82-0.51-0.18-0.09
Diluted Shares Outstanding
153.36M185.79M240.42M258.87M271.42M289.06M295.16M304.38M308.36M
Basic Shares Outstanding
153.36M185.79M240.42M258.87M271.42M289.06M295.16M304.38M308.36M
Dividend Payout Ratio
---------

FOLD Balance Sheet

Amicus Therapeutics, Inc. (FOLD) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets
391.96M551.1M520.07M579.47M596.83M423.82M483.06M504.74M676.17M
Cash & Short-Term Investments
358.56M504.15M452.74M483.27M482.5M293.6M286.2M249.95M293.54M
Cash Only
49.06M79.75M142.84M163.24M245.2M148.81M246.99M213.75M214.01M
Short-Term Investments
309.5M424.4M309.9M320.03M237.3M144.78M39.21M36.19M79.53M
Accounts Receivable
9.46M21.96M33.28M46.92M52.67M66.2M87.63M101.1M115.31M
Days Sales Outstanding
93.5487.8566.6665.6562.9373.3980.0969.8566.36
Inventory
4.62M8.39M14.04M19.56M26.82M23.82M59.7M118.78M228.82M
Days Inventory Outstanding
270.59212.6233.35229.93284.01225.21583.75818.911.04K
Other Current Assets
19.32M16.59M00040.21M49.53M34.91M38.51M
Total Non-Current Assets
235.06M238.85M330.13M307.05M308.31M300.35M294.82M280.3M273.7M
Property, Plant & Equipment
9.06M11.38M81.02M67.16M63.08M60.31M57.98M51.66M48.25M
Fixed Asset Turnover
4.08x8.02x2.25x3.88x4.84x5.46x6.89x10.23x13.15x
Goodwill
197.8M197.8M197.8M197.8M197.8M197.8M197.8M197.8M197.8M
Intangible Assets
23M23M23M23M23M23M20.49M17.2M13.91M
Long-Term Investments
-6.46M-6.46M0000000
Other Non-Current Assets
5.2M6.68M28.32M19.09M24.43M19.24M18.55M13.64M13.74M
Total Assets
627.02M▲ 0%
789.95M▲ 26.0%
850.21M▲ 7.6%
886.52M▲ 4.3%
905.14M▲ 2.1%
724.17M▼ 20.0%
777.88M▲ 7.4%
785.03M▲ 0.9%
949.87M▲ 21.0%
Asset Turnover
0.06x0.12x0.21x0.29x0.34x0.45x0.51x0.67x0.67x
Asset Growth %
-39.53%25.98%7.63%4.27%2.1%-19.99%7.42%0.92%21%
Total Current Liabilities
70.04M86.13M128.81M129.68M145.97M139.02M167.69M148.7M237.83M
Accounts Payable
7.87M6.61M21.72M17.06M21.51M15.41M15.12M12.95M28.63M
Days Payables Outstanding
460.46167.4360.99200.62227.83145.75147.8589.26129.99
Short-Term Debt
000000008.74M
Deferred Revenue (Current)
7.75M5.5M0000000
Other Current Liabilities
30.82M32.06M31.18M27.12M28.46M33.17M48.68M41.23M133.97M
Current Ratio
5.60x6.40x4.04x4.47x4.09x3.05x2.88x3.39x2.84x
Quick Ratio
5.53x6.30x3.93x4.32x3.90x2.88x2.52x2.60x1.88x
Cash Conversion Cycle
-96.34133.06-60.9994.96119.11152.85515.99799.5975.3
Total Non-Current Liabilities
204.13M360.91M244.97M470.46M451.8M462.1M450.02M442.29M437.8M
Long-Term Debt
164.17M321.74M149.5M389.25M389.36M391.99M387.86M390.11M433.62M
Capital Lease Obligations
0053.53M45.6M43.36M51.58M48.88M45.08M40.96M
Deferred Tax Liabilities
6.46M6.46M5.05M4.9M4.93M4.94M000
Other Non-Current Liabilities
33.5M32.71M36.88M30.71M14.15M13.6M13.28M7.1M-36.78M
Total Liabilities
274.17M447.04M373.78M600.14M597.77M601.12M617.71M590.99M675.63M
Total Debt
164.47M321.74M210.22M441.73M440.13M452.12M445.06M443.64M483.32M
Net Debt
115.41M241.99M67.39M278.49M194.93M303.31M198.06M229.89M269.31M
Debt / Equity
0.47x0.94x0.44x1.54x1.43x3.67x2.78x2.29x1.76x
Debt / EBITDA
-------13.27x11.52x
Net Debt / EBITDA
-------6.88x6.42x
Interest Coverage
-25.05x-14.58x-17.86x-11.23x-6.44x-5.52x-1.99x0.42x1.00x
Total Equity
352.85M▲ 0%
342.91M▼ 2.8%
476.43M▲ 38.9%
286.38M▼ 39.9%
307.37M▲ 7.3%
123.05M▼ 60.0%
160.17M▲ 30.2%
194.04M▲ 21.1%
274.24M▲ 41.3%
Equity Growth %
-2.03%-2.82%38.94%-39.89%7.33%-59.97%30.17%21.15%41.33%
Book Value per Share
2.301.851.981.111.130.430.540.640.89
Total Shareholders' Equity
352.85M342.91M476.43M286.38M307.37M123.05M160.17M194.04M274.24M
Common Stock
1.72M1.94M2.6M2.65M2.81M2.81M2.92M2.94M3.04M
Retained Earnings
-1.06B-1.41B-1.77B-2.05B-2.3B-2.53B-2.68B-2.74B-2.77B
Treasury Stock
00000000-71K
Accumulated OCI
-2.1M68K2.83M8.23M4.98M-12.11M5.24M5.09M24.11M
Minority Interest
000000000

FOLD Cash Flow Statement

Amicus Therapeutics, Inc. (FOLD) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations
-215.49M-299.95M-250.42M-233.29M-202.49M-166.57M-69.09M-33.89M33.15M
Operating CF Margin %
-583.5%-328.74%-137.41%-89.42%-66.28%-50.59%-17.3%-6.42%5.23%
Operating CF Growth %
-43.15%-39.2%16.52%6.84%13.2%17.74%58.52%50.95%197.8%
Net Income
-284M-349M-356.39M-276.85M-250.46M-236.57M-151.58M-56.11M-27.11M
Depreciation & Amortization
3.59M4.22M4.78M8.85M6.21M5.34M7.87M8.55M2.57M
Stock-Based Compensation
23.1M29.26M44.43M49.15M57.84M76.51M86.08M84.91M87.41M
Deferred Taxes
-167.31M6.01M-1.42M-155K34K9K-4.94M00
Other Non-Cash Items
234.91M14.28M46.57M17.78M2.47M28.01M41.47M27.71M9.91M
Working Capital Changes
-25.79M-4.73M11.61M-32.06M-18.59M-39.88M-47.99M-98.94M-39.63M
Change in Receivables
-7.72M-13.29M-11.11M-11.22M-8.19M-17.33M-20.11M-19.48M-5.86M
Change in Inventory
-897K-4.21M-5.11M-4.64M-7.79M-5.34M-44.61M-73.65M-111.48M
Change in Payables
12.56M17.11M46.74M-10.61M7.43M-6.38M49.2M-16.52M82.78M
Cash from Investing
-171.24M-121.2M95.15M-13.58M78.76M92.32M98.06M-560K-46.43M
Capital Expenditures
-4.53M-6.31M-20.01M-3.23M-3.88M-3.77M-7.44M-3.55M-3.3M
CapEx % of Revenue
12.26%6.91%10.98%1.24%1.27%1.14%1.86%0.67%0.52%
Acquisitions
06.31M0003.41M000
Investments
---------
Other Investing
-166.72M-6.31M0000000
Cash from Financing
247.43M450.77M217.5M262.86M212.07M-7.46M61.68M5.12M610K
Debt Issued (Net)
-308K146.26M-420K230.6M-479K-283K-20.96M-97K-272K
Equity Issued (Net)
243.04M294.58M188.99M0199.75M-7.18M103.21M27.24M19.2M
Dividends Paid
000000000
Share Repurchases
-1.6M-2.83M000-11.49M000
Other Financing
4.71M9.93M28.93M32.25M12.8M0-20.57M-22.02M-18.32M
Net Change in Cash
-137.97M▲ 0%
31.14M▲ 122.6%
63.97M▲ 105.4%
19.82M▼ 69.0%
83.29M▲ 320.3%
-96.34M▼ 215.7%
96.96M▲ 200.6%
-33.36M▼ 134.4%
600K▲ 101.8%
Free Cash Flow
-220.01M▲ 0%
-306.26M▼ 39.2%
-270.43M▲ 11.7%
-236.52M▲ 12.5%
-206.38M▲ 12.7%
-170.34M▲ 17.5%
-76.53M▲ 55.1%
-37.44M▲ 51.1%
29.85M▲ 179.7%
FCF Margin %
-595.75%-335.65%-148.39%-90.66%-67.55%-51.74%-19.16%-7.09%4.71%
FCF Growth %
-40.6%-39.2%11.7%12.54%12.74%17.46%55.07%51.07%179.72%
FCF per Share
-1.43-1.65-1.12-0.91-0.76-0.59-0.26-0.120.10
FCF Conversion (FCF/Net Income)
0.76x0.86x0.70x0.84x0.81x0.70x0.46x0.60x-1.22x
Interest Paid
07.5M16.97M24.68M30.47M34.36M36.09M58.96M0
Taxes Paid
01.06M691K10.37M20.03M1.07M8.53M8.21M0

FOLD Key Ratios

Amicus Therapeutics, Inc. (FOLD) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)
-56.51%-79.66%-100.32%-86.99%-72.59%-84.37%-109.93%-107.04%-31.68%-11.58%
Return on Invested Capital (ROIC)
-42.13%-83.3%-46.83%-40.4%-33.42%-29.02%-34.26%-14.76%4.77%5.35%
Gross Margin
83.2%83.11%84.21%87.95%88.1%88.72%88.28%90.65%89.98%87.32%
Net Margin
-4034.73%-769.03%-382.48%-195.56%-106.12%-81.98%-71.85%-37.96%-10.62%-4.27%
Debt / Equity
0.43x0.47x0.94x0.44x1.54x1.43x3.67x2.78x2.29x1.76x
Interest Coverage
-36.75x-25.05x-14.58x-17.86x-11.23x-6.44x-5.52x-1.99x0.42x1.00x
FCF Conversion
0.75x0.76x0.86x0.70x0.84x0.81x0.70x0.46x0.60x-1.22x
Revenue Growth
-644.86%147.08%99.72%43.16%17.11%7.76%21.3%32.29%20.05%
Related:FOLD Dividend History·FOLD Revenue History·FOLD Price History·FOLD P/E History·FOLD Financial Ratios·FOLD Institutional Holders

FOLD SEC Filings & Documents

Amicus Therapeutics, Inc. (FOLD) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Apr 27, 2026·SEC

Material company update

Apr 23, 2026·SEC

Material company update

Mar 3, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 20, 2026·SEC

FY 2025

Feb 19, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 4, 2025·SEC

FY 2025

Jul 31, 2025·SEC

FY 2025

May 1, 2025·SEC

FOLD Frequently Asked Questions

Amicus Therapeutics, Inc. (FOLD) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Amicus Therapeutics, Inc. (FOLD) reported $634.2M in revenue for fiscal year 2025.

Amicus Therapeutics, Inc. (FOLD) grew revenue by 20.0% over the past year. This is strong growth.

Amicus Therapeutics, Inc. (FOLD) reported a net loss of $27.1M for fiscal year 2025.

Dividend & Returns

Amicus Therapeutics, Inc. (FOLD) has a return on equity (ROE) of -11.6%. Negative ROE indicates the company is unprofitable.

Amicus Therapeutics, Inc. (FOLD) generated $29.8M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

What if you invested $1,000 in FOLD back in 2005?

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