8-K Announcements
6Apr 7, 2026·SEC
Apr 6, 2026·SEC
Mar 16, 2026·SEC
Soleno Therapeutics, Inc. (SLNO) fundamental analysis — strengths, weaknesses & financial health based on data analysis
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
Soleno Therapeutics, Inc. (SLNO) stock price & volume — 10-year historical chart
Soleno Therapeutics, Inc. (SLNO) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Soleno Therapeutics, Inc. (SLNO) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q1 2026Latest | Feb 25, 2026 | $0.80vs $0.64+25.0% | $92Mvs $89M+3.4% |
| Q4 2025 | Nov 4, 2025 | $0.47vs $0.06+717.4% | $66Mvs $89M-25.4% |
| Q3 2025 | Aug 6, 2025 | $0.09vs $0.53+83.0% | $33Mvs $39M-17.0% |
| Q2 2025 | May 7, 2025 | $0.95vs $1.14+16.7% | — |
Soleno Therapeutics, Inc. (SLNO) competitors in Commercial Rare Disease Biopharma — business model, growth, and fundamentals comparison
Soleno Therapeutics, Inc. (SLNO) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
Soleno Therapeutics, Inc. (SLNO) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | -1.55B | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 190.41M |
| Revenue Growth % | -107145.41% | 100% | - | - | - | - | - | - | - |
| Cost of Goods Sold | 1.61M | 1.92M | 2.3M | 2.19M | 0 | 0 | 0 | 0 | 2.7M |
| COGS % of Revenue | -0.1% | - | - | - | - | - | - | - | 1.42% |
| Gross Profit | -1.55B▲ 0% | -1.92M▲ 99.9% | -2.3M▼ 19.7% | -2.19M▲ 4.5% | 0▲ 100.0% | 0▲ 0% | 0▲ 0% | 0▲ 0% | 187.71M▲ 0% |
| Gross Margin % | 100.1% | - | - | - | - | - | - | - | 98.58% |
| Gross Profit Growth % | -2656540.69% | 99.88% | -19.7% | 4.48% | 100% | - | - | - | - |
| Operating Expenses | 9.68M | 13.73M | 20.9M | 29.75M | 31.53M | 24.4M | 41.38M | 187.67M | 172.75M |
| OpEx % of Revenue | -0.62% | - | - | - | - | - | - | - | 90.73% |
| Selling, General & Admin | 6.61M | 6.56M | 4.63M | 6.56M | 10.81M | 9.84M | 13.48M | 105.86M | 132.13M |
| SG&A % of Revenue | -0.43% | - | - | - | - | - | - | - | 69.39% |
| Research & Development | 3.07M | 7.18M | 16.27M | 23.19M | 21.45M | 15.27M | 25.19M | 78.57M | 40.63M |
| R&D % of Revenue | -0.2% | - | - | - | - | - | - | - | 21.34% |
| Other Operating Expenses | -585.95K | 6K | 0 | 0 | -731K | -712K | 2.71M | 3.24M | 0 |
| Operating Income | -12.17M▲ 0% | -14.3M▼ 17.5% | -23.2M▼ 62.2% | -31.95M▼ 37.7% | -31.53M▲ 1.3% | -24.4M▲ 22.6% | -41.38M▼ 69.6% | -187.67M▼ 353.5% | 14.95M▲ 108.0% |
| Operating Margin % | 0.78% | - | - | - | - | - | - | - | 7.85% |
| Operating Income Growth % | 10.57% | -17.5% | -62.21% | -37.73% | 1.32% | 22.62% | -69.63% | -353.49% | 107.97% |
| EBITDA | -10.56M | -12.38M | -20.9M | -29.75M | -29.57M | -22.43M | -39.43M | -185.68M | 16.97M |
| EBITDA Margin % | 0.68% | - | - | - | - | - | - | - | 8.91% |
| EBITDA Growth % | 22.3% | -17.25% | -68.79% | -42.37% | 0.64% | 24.12% | -75.75% | -370.97% | 109.14% |
| D&A (Non-Cash Add-back) | 1.61M | 1.92M | 2.3M | 2.19M | 1.96M | 1.96M | 1.96M | 1.99M | 2.02M |
| EBIT | -13.44M | -13.73M | -30.77M | -24.64M | -32.26M | -24.07M | -38.99M | -175.62M | 26.37M |
| Net Interest Income | 0 | 0 | 154K | 13K | 110K | 300K | 2.58M | 11.82M | 11.48M |
| Interest Income | 0 | 0 | 154K | 13K | 110K | 300K | 2.58M | 12.05M | 16.95M |
| Interest Expense | 0 | 62K | 0 | 0 | 0 | 0 | 0 | 231K | 5.48M |
| Other Income/Expense | -1.27M | 2.46M | -7.58M | 7.31M | 618K | 330K | 2.4M | 11.82M | 5.94M |
| Pretax Income | -13.72M▲ 0% | -11.84M▲ 13.7% | -30.77M▼ 159.9% | -24.64M▲ 19.9% | -30.91M▼ 25.5% | -24.07M▲ 22.1% | -38.99M▼ 62.0% | -175.85M▼ 351.0% | 20.89M▲ 111.9% |
| Pretax Margin % | 0.88% | - | - | - | - | - | - | - | 10.97% |
| Income Tax | -1.65M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 12.03% | 0% | 0% | 0% | 0% | 0% | 0% | 0% | 0% |
| Net Income | -15.67M▲ 0% | -13.34M▲ 14.9% | -30.77M▼ 130.8% | -24.64M▲ 19.9% | -30.91M▼ 25.5% | -24.07M▲ 22.1% | -38.99M▼ 62.0% | -175.85M▼ 351.0% | 20.89M▲ 111.9% |
| Net Margin % | 1.01% | - | - | - | - | - | - | - | 10.97% |
| Net Income Growth % | -29.86% | 14.89% | -130.78% | 19.94% | -25.45% | 22.14% | -62% | -351.04% | 111.88% |
| Net Income (Continuing) | -11.79M | -11.84M | -30.77M | -24.64M | -30.91M | -24.07M | -38.99M | -175.85M | 20.89M |
| Discontinued Operations | -3.59M | -1.49M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -26.18▲ 0% | -9.54▲ 63.6% | -15.78▼ 65.4% | -3.68▲ 76.7% | -5.81▼ 57.9% | -2.87▲ 50.6% | -2.36▲ 17.8% | -4.38▼ 85.6% | 0.39▲ 108.9% |
| EPS Growth % | 55.13% | 63.56% | -65.41% | 76.68% | -57.88% | 50.6% | 17.77% | -85.59% | 108.9% |
| EPS (Basic) | -26.18 | -9.54 | -15.78 | -3.68 | -5.81 | -2.87 | -2.36 | -4.38 | 0.41 |
| Diluted Shares Outstanding | 598.52K | 1.4M | 2.28M | 4.17M | 5.32M | 8.4M | 16.49M | 40.18M | 54.33M |
| Basic Shares Outstanding | 598.52K | 1.4M | 2.28M | 4.17M | 5.32M | 8.4M | 16.49M | 40.18M | 53.18M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
Soleno Therapeutics, Inc. (SLNO) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 17.99M | 24.67M | 21.14M | 50.24M | 22.42M | 15.65M | 171.36M | 293.89M | 355.81M |
| Cash & Short-Term Investments | 17.1M | 24.08M | 20.73M | 49.22M | 21.3M | 14.6M | 169.68M | 291.44M | 305.47M |
| Cash Only | 17.1M | 23.1M | 20.73M | 49.22M | 21.3M | 14.6M | 169.68M | 87.93M | 70.11M |
| Short-Term Investments | 0 | 978K | 0 | 0 | 0 | 0 | 0 | 203.51M | 235.37M |
| Accounts Receivable | 0 | 64K | 0 | 0 | 0 | 0 | 0 | 0 | 28.21M |
| Days Sales Outstanding | - | - | - | - | - | - | - | - | 54.07 |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 15.02M |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | 2.03K |
| Other Current Assets | 551K | 0 | 0 | 0 | 0 | 1.04M | 1.68M | 2.45M | 7.11M |
| Total Non-Current Assets | 21.03M | 18.48M | 17.03M | 14.74M | 13.13M | 10.85M | 9.33M | 37.08M | 208.02M |
| Property, Plant & Equipment | 22.89K | 12K | 444K | 158K | 454K | 157K | 419K | 2.98M | 2.38M |
| Fixed Asset Turnover | -67861.13x | - | - | - | - | - | - | - | 80.14x |
| Goodwill | 125.53K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 20.41M | 18.47M | 16.52M | 14.58M | 12.64M | 10.69M | 8.75M | 6.8M | 4.86M |
| Long-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 27.21M | 0 |
| Other Non-Current Assets | 591.92K | 0 | 59K | 0 | 40K | 0 | 165K | 83K | 200.78M |
| Total Assets | 39.02M▲ 0% | 43.15M▲ 10.6% | 38.17M▼ 11.5% | 64.98M▲ 70.2% | 35.55M▼ 45.3% | 26.5M▼ 25.5% | 180.69M▲ 581.9% | 330.97M▲ 83.2% | 563.83M▲ 70.4% |
| Asset Turnover | -39.80x | - | - | - | - | - | - | - | 0.34x |
| Asset Growth % | 601.22% | 10.58% | -11.54% | 70.23% | -45.29% | -25.47% | 581.93% | 83.17% | 70.36% |
| Total Current Liabilities | 1.73M | 1.88M | 4.96M | 8.62M | 8.01M | 7.31M | 11.51M | 18.75M | 61.36M |
| Accounts Payable | 633K | 934K | 2M | 3.49M | 3.25M | 1.78M | 3.15M | 8.88M | 12.44M |
| Days Payables Outstanding | 143.42 | 177.65 | 317.01 | 580.44 | - | - | - | - | 1.68K |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 726K |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 127K | 623K | 665K | 1.2M | 1.05M | 2.16M | 4.95M | 9.34M | 48.2M |
| Current Ratio | 10.38x | 13.14x | 4.26x | 5.83x | 2.80x | 2.14x | 14.89x | 15.68x | 5.80x |
| Quick Ratio | 10.38x | 13.14x | 4.26x | 5.83x | 2.80x | 2.14x | 14.89x | 15.68x | 5.55x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | 404.07 |
| Total Non-Current Liabilities | 10.75M | 10.86M | 18.26M | 10.82M | 9.75M | 8.84M | 11.68M | 67.11M | 52.35M |
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 49.83M | 1.96M |
| Capital Lease Obligations | 0 | 0 | 0 | 0 | 175K | 0 | 130K | 2.47M | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 10.47M | 10.86M | 18.26M | 10.82M | 9.58M | 8.84M | 11.55M | 14.81M | 50.39M |
| Total Liabilities | 12.49M | 12.74M | 23.23M | 19.43M | 17.76M | 16.15M | 23.18M | 85.86M | 113.72M |
| Total Debt | 0 | 0 | 305K | 139K | 457K | 155K | 403K | 52.83M | 2.69M |
| Net Debt | -17.1M | -23.1M | -20.43M | -49.09M | -20.85M | -14.45M | -169.28M | -35.1M | -67.42M |
| Debt / Equity | - | - | 0.02x | 0.00x | 0.03x | 0.01x | 0.00x | 0.22x | 0.01x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | 0.16x |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | -3.97x |
| Interest Coverage | - | -221.52x | - | - | - | - | - | -760.26x | 4.81x |
| Total Equity | 26.53M▲ 0% | 30.41M▲ 14.6% | 14.95M▼ 50.9% | 45.55M▲ 204.7% | 17.79M▼ 60.9% | 10.35M▼ 41.8% | 157.51M▲ 1422.1% | 245.11M▲ 55.6% | 450.12M▲ 83.6% |
| Equity Growth % | 672.44% | 14.62% | -50.85% | 204.72% | -60.93% | -41.84% | 1422.1% | 55.62% | 83.64% |
| Book Value per Share | 44.33 | 21.75 | 6.57 | 10.91 | 3.35 | 1.23 | 9.55 | 6.10 | 8.28 |
| Total Shareholders' Equity | 26.53M | 30.41M | 14.95M | 45.55M | 17.79M | 10.35M | 157.51M | 245.11M | 450.12M |
| Common Stock | 19.24K | 32K | 45K | 80K | 80K | 8K | 32K | 46K | 52K |
| Retained Earnings | -113.98M | -127.03M | -157.81M | -182.44M | -213.35M | -237.42M | -276.41M | -452.26M | -431.37M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -73.65K | -93K | 0 | 0 | 0 | 0 | 0 | 361K | 415K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Soleno Therapeutics, Inc. (SLNO) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -9.95M | -11.68M | -17.38M | -25.22M | -27.77M | -20.78M | -24.94M | -69.1M | 46.8M |
| Operating CF Margin % | 0.64% | - | - | - | - | - | - | - | 24.58% |
| Operating CF Growth % | 26.29% | -17.42% | -48.72% | -45.17% | -10.09% | 25.17% | -20.01% | -177.05% | 167.73% |
| Net Income | -12.07M | -11.84M | -30.77M | -24.64M | -30.91M | -24.07M | -38.99M | -175.85M | 20.89M |
| Depreciation & Amortization | 1.61M | 1.96M | 1.96M | 1.95M | 1.96M | 1.96M | 1.96M | 1.99M | 2.02M |
| Stock-Based Compensation | 880.03K | 988K | 825K | 1.5M | 3.28M | 2.53M | 5.95M | 99.96M | 45.85M |
| Deferred Taxes | -1.65M | -3.88M | 6.96M | -11.64M | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 1.31M | 1M | 1.15M | 4.62M | -951K | -452K | 3.22M | -1.21M | 2.68M |
| Working Capital Changes | -24.07K | 82K | 2.5M | 2.98M | -1.15M | -756K | 2.93M | 6.02M | -24.63M |
| Change in Receivables | 0 | -64K | 64K | 0 | 0 | 0 | 0 | 0 | -28.21M |
| Change in Inventory | 0 | 0 | -64K | 0 | 0 | 0 | 0 | 0 | -14.03M |
| Change in Payables | 190.63K | 249K | 1.06M | 1.49M | -235K | -1.48M | 1.37M | 5.67M | 3.61M |
| Cash from Investing | 378.78K | -180K | 528K | -7K | -22K | -13K | 0 | -225.68M | -201.78M |
| Capital Expenditures | -2.57K | -8K | -21K | -7K | -22K | -13K | 0 | -218K | -73K |
| CapEx % of Revenue | -0% | - | - | - | - | - | - | - | 0.04% |
| Acquisitions | -572.59K | 0 | 500K | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | 953.94K | -172K | 49K | 0 | 0 | 0 | 0 | 0 | 0 |
| Cash from Financing | 23.94M | 17.83M | 14.48M | 53.72M | -128K | 14.09M | 180.02M | 213.03M | 137.16M |
| Debt Issued (Net) | 0 | 0 | -2K | -17K | -8K | 0 | 0 | 49.89M | 0 |
| Equity Issued (Net) | 25.01M | 16.3M | 14.48M | 53.72M | 0 | 14.11M | 137.86M | 148.96M | 137.96M |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -100.15M |
| Other Financing | -838K | 1.52M | 0 | 17K | -120K | -16K | 42.16M | 14.18M | -803K |
| Net Change in Cash | 14.37M▲ 0% | 5.96M▼ 58.5% | -2.37M▼ 139.7% | 28.49M▲ 1304.2% | -27.92M▼ 198.0% | -6.7M▲ 76.0% | 155.08M▲ 2413.9% | -81.75M▼ 152.7% | -17.82M▲ 78.2% |
| Free Cash Flow | -9.95M▲ 0% | -11.69M▼ 17.5% | -17.4M▼ 48.8% | -25.23M▼ 45.0% | -27.79M▼ 10.2% | -20.79M▲ 25.2% | -24.94M▼ 19.9% | -69.31M▼ 177.9% | 46.73M▲ 167.4% |
| FCF Margin % | 0.64% | - | - | - | - | - | - | - | 24.54% |
| FCF Growth % | 26.48% | -17.47% | -48.8% | -45.04% | -10.15% | 25.18% | -19.94% | -177.92% | 167.41% |
| FCF per Share | -16.63 | -8.36 | -7.64 | -6.04 | -5.23 | -2.48 | -1.51 | -1.73 | 0.86 |
| FCF Conversion (FCF/Net Income) | 0.64x | 0.88x | 0.56x | 1.02x | 0.90x | 0.86x | 0.64x | 0.39x | 2.24x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 800 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Soleno Therapeutics, Inc. (SLNO) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -362.37% | -104.55% | -46.83% | -135.69% | -81.46% | -97.6% | -171.05% | -46.45% | -87.35% | 6.01% |
| Return on Invested Capital (ROIC) | -1439.31% | -179.97% | -128.07% | -1898.28% | - | - | - | - | -142% | 3.78% |
| Gross Margin | -4.03% | 100.1% | - | - | - | - | - | - | - | 98.58% |
| Net Margin | -831.63% | 1.01% | - | - | - | - | - | - | - | 10.97% |
| Debt / Equity | - | - | - | 0.02x | 0.00x | 0.03x | 0.01x | 0.00x | 0.22x | 0.01x |
| Interest Coverage | - | - | -221.52x | - | - | - | - | - | -760.26x | 4.81x |
| FCF Conversion | 1.12x | 0.64x | 0.88x | 0.56x | 1.02x | 0.90x | 0.86x | 0.64x | 0.39x | 2.24x |
| Revenue Growth | 274.34% | -107145.41% | 100% | - | - | - | - | - | - | - |
Soleno Therapeutics, Inc. (SLNO) SEC filings — annual & quarterly reports (10-K, 10-Q)
Apr 7, 2026·SEC
Apr 6, 2026·SEC
Mar 16, 2026·SEC
Soleno Therapeutics, Inc. (SLNO) stock FAQ — growth, dividends, profitability & financials explained
Soleno Therapeutics, Inc. (SLNO) reported $190.4M in revenue for fiscal year 2025.
Soleno Therapeutics, Inc. (SLNO) grew revenue by 0.0% over the past year. Growth has been modest.
Yes, Soleno Therapeutics, Inc. (SLNO) is profitable, generating $20.9M in net income for fiscal year 2025 (11.0% net margin).
Soleno Therapeutics, Inc. (SLNO) has a return on equity (ROE) of 6.0%. This is below average, suggesting room for improvement.
Soleno Therapeutics, Inc. (SLNO) generated $46.9M in free cash flow for fiscal year 2025. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.
Soleno Therapeutics, Inc. (SLNO) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates