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Krystal Biotech, Inc. (KRYS) 10-Year Financial Performance & Capital Metrics

KRYS • • Industrial / General
HealthcareBiotechnologyRare Genetic DiseasesGene Therapy & Rare Diseases
AboutKrystal Biotech, Inc., a clinical stage biotechnology company, engages in the field of redosable gene therapy to treat serious rare diseases in the United States. Its lead product candidate is beremagene geperpavec (B-VEC), which is in Phase III clinical study to treat dystrophic epidermolysis bullosa. The company is also involved in developing KB105 that is in Phase I/II clinical study for treating patients with deficient autosomal recessive congenital ichthyosis; KB301, which is in Phase I/II clinical stage for treating wrinkles and other presentations of aged or damaged skin; KB407 that is in preclinical stage for cystic fibrosis; and KB104, which is in preclinical stage for netherton syndrome. Its discovery stage product candidates include KB5xx for treating chronic skin diseases, KB3xx to treat aesthetic skin conditions, and KB3xx product. Krystal Biotech, Inc. was founded in 2015 and is headquartered in Pittsburgh, Pennsylvania.Show more
  • Revenue $291M +473.0%
  • EBITDA $72M +169.7%
  • Net Income $89M +715.6%
  • EPS (Diluted) 3.00 +669.2%
  • Gross Margin 93.09% -0.9%
  • EBITDA Margin 24.92% +112.2%
  • Operating Margin 22.61% +110.4%
  • Net Margin 30.69% +42.3%
  • ROE 10.34% +515.0%
  • ROIC 9.5% +146.0%
  • Debt/Equity 0.01 -26.2%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓FCF machine: 41.0% free cash flow margin
  • ✓Momentum leader: RS Rating 91 (top 9%)
  • ✓High quality earnings: Operating CF exceeds net income
  • ✓Healthy 5Y average net margin of 26.1%
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM54.51%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM279.8%

EPS CAGR

10Y-
5Y-
3Y-
TTM276.85%

ROCE

10Y Avg-18.18%
5Y Avg-12.65%
3Y Avg-11.61%
Latest7.56%

Peer Comparison

Gene Therapy & Rare Diseases
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
KRYSKrystal Biotech, Inc.8.18B282.0194.00473.02%53.3%17.48%1.46%0.01
BMRNBioMarin Pharmaceutical Inc.10.58B55.0724.9217.97%16.82%8.59%4.49%0.11
SRPTSarepta Therapeutics, Inc.2.23B21.319.1152.97%-11.25%-20.57%0.88
RAREUltragenyx Pharmaceutical Inc.2.27B23.50-3.7429.01%-91.95%-35.88%0.15
DYNDyne Therapeutics, Inc.2.7B16.42-4.87-61.26%0.04
TVTXTravere Therapeutics, Inc.2.54B28.40-6.9660.55%-20.32%-120.36%6.80
BEAMBeam Therapeutics Inc.3.25B32.05-7.00-83.18%-7.44%-42.92%0.22
SLNOSoleno Therapeutics, Inc.2.25B41.95-9.58-79.5%-15.85%0.22

Profit & Loss

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+001.03M000050.7M290.51M
Revenue Growth %----1%----4.73%
Cost of Goods Sold+2K23K141K974K1.85M003.09M20.06M
COGS % of Revenue--0.14%----0.06%0.07%
Gross Profit+-2K-23K886K-974K-1.85M0047.6M270.45M
Gross Margin %--0.86%----0.94%0.93%
Gross Profit Growth %--10.5%39.52%-2.1%-0.9%1%--4.68%
Operating Expenses+1.14M4.77M11.92M22.08M31.15M68.28M145.2M157.33M204.76M
OpEx % of Revenue--11.6%----3.1%0.7%
Selling, General & Admin402K1.56M4.16M6.46M13.21M40.39M77.73M98.4M113.69M
SG&A % of Revenue--4.05%----1.94%0.39%
Research & Development741K3.21M7.76M15.62M17.94M27.88M42.46M46.43M53.57M
R&D % of Revenue--7.56%----0.92%0.18%
Other Operating Expenses00000025M12.5M37.5M
Operating Income+-1.14M-4.77M-11.92M-22.08M-33M-68.28M-145.2M-109.73M65.69M
Operating Margin %---11.6%-----2.16%0.23%
Operating Income Growth %--3.17%-1.5%-0.85%-0.49%-1.07%-1.13%0.24%1.6%
EBITDA+-1.14M-4.75M-11.78M-21.11M-31.15M-66.43M-141.81M-103.82M72.41M
EBITDA Margin %---11.47%-----2.05%0.25%
EBITDA Growth %--3.16%-1.48%-0.79%-0.48%-1.13%-1.13%0.27%1.7%
D&A (Non-Cash Add-back)2K23K141K974K1.85M1.85M3.38M5.91M6.71M
EBIT-1.14M-4.66M-10.89M-19.09M-32.17M-68.08M-120.2M-97.23M103.19M
Net Interest Income+0002.99M832K-1.29M5.22M22.62M29.66M
Interest Income0002.99M832K197K5.22M22.62M29.66M
Interest Expense7K3.15M1.03M001.49M000
Other Income/Expense-7K-3.15M1.03M2.99M832K-1.29M5.22M122.62M29.66M
Pretax Income+-1.15M-7.92M-10.89M-19.09M-32.17M-69.57M-139.97M12.9M95.36M
Pretax Margin %---10.6%----0.25%0.33%
Income Tax+00-20.14K00001.97M6.2M
Effective Tax Rate %1%1%1%1%1%1%1%0.85%0.94%
Net Income+-1.15M-7.92M-10.89M-19.09M-32.17M-69.57M-139.97M10.93M89.16M
Net Margin %---10.6%----0.22%0.31%
Net Income Growth %--5.89%-0.37%-0.75%-0.69%-1.16%-1.01%1.08%7.16%
Net Income (Continuing)-1.15M-7.92M-10.89M-19.09M-32.17M-69.57M-139.97M10.93M89.16M
Discontinued Operations000000000
Minority Interest000000000
EPS (Diluted)+-0.27-1.48-0.97-1.20-1.71-3.13-5.490.393.00
EPS Growth %--4.48%0.34%-0.24%-0.42%-0.83%-0.75%1.07%6.69%
EPS (Basic)-0.27-1.48-0.97-1.20-1.71-3.13-5.490.403.12
Diluted Shares Outstanding4.28M5.36M11.2M15.9M18.79M22.2M25.49M27.75M29.74M
Basic Shares Outstanding4.28M5.36M11.2M15.9M18.79M22.2M25.49M27.15M28.59M
Dividend Payout Ratio---------

Balance Sheet

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+2.17M49.91M112.65M195.88M275.06M442.27M383.78M587.91M742.04M
Cash & Short-Term Investments1.92M49.59M111.76M193.69M271.26M438.1M379.17M532.18M597.52M
Cash Only1.92M49.59M103.67M187.51M268.27M341.25M161.9M358.33M344.87M
Short-Term Investments008.09M6.17M2.99M96.85M217.27M173.85M252.65M
Accounts Receivable000000042.04M104.75M
Days Sales Outstanding-------302.66131.6
Inventory00000006.99M26.51M
Days Inventory Outstanding-------824.02482.3
Other Current Assets0000004.61M6.71M13.27M
Total Non-Current Assets+13K200K3.47M13.14M35.79M184.03M174.67M230.45M313.79M
Property, Plant & Equipment13K200K3.01M11.18M34.17M119.58M169.73M168.23M161.45M
Fixed Asset Turnover--0.34x----0.30x1.80x
Goodwill000000000
Intangible Assets000000000
Long-Term Investments000497K064.37M4.62M61.95M152.11M
Other Non-Current Assets00452K1.46M1.61M74K324K263K231K
Total Assets+2.18M50.11M116.12M209.02M310.84M626.29M558.45M818.36M1.06B
Asset Turnover--0.01x----0.06x0.28x
Asset Growth %-21.97%1.32%0.8%0.49%1.01%-0.11%0.47%0.29%
Total Current Liabilities+43K640K2.6M3.33M15.45M25.74M28.85M33.09M102M
Accounts Payable42K193K888K1.02M2.1M8.4M3.98M1.85M4.99M
Days Payables Outstanding7.67K3.06K2.3K382.61415.09--218.1390.7
Short-Term Debt000000000
Deferred Revenue (Current)000000000
Other Current Liabilities0437K1.36M12K26K87K267K16.75M2.4M
Current Ratio50.44x77.99x43.39x58.88x17.80x17.18x13.30x17.76x7.28x
Quick Ratio50.44x77.99x43.39x58.88x17.80x17.18x13.30x17.55x7.02x
Cash Conversion Cycle-------908.56523.2
Total Non-Current Liabilities+1.85M0294K2.78M3.31M6.98M7.37M6.62M7.46M
Long-Term Debt1.84M00000000
Capital Lease Obligations0002.78M3.31M6.98M7.37M6.62M6.04M
Deferred Tax Liabilities000000000
Other Non-Current Liabilities7K0294K000001.42M
Total Liabilities1.89M640K2.89M6.11M18.76M32.72M36.22M39.71M109.46M
Total Debt+1.84M003.26M11.55M8.02M8.93M8.09M7.26M
Net Debt-80K-49.59M-103.67M-184.25M-256.72M-333.22M-152.97M-350.23M-337.6M
Debt / Equity6.38x--0.02x0.04x0.01x0.02x0.01x0.01x
Debt / EBITDA--------0.10x
Net Debt / EBITDA---------4.66x
Interest Coverage-163.29x-1.52x-11.60x---45.76x---
Total Equity+289K49.47M113.23M202.91M292.08M593.58M522.23M778.64M946.38M
Equity Growth %-170.19%1.29%0.79%0.44%1.03%-0.12%0.49%0.22%
Book Value per Share0.079.2310.1112.7615.5526.7420.4928.0631.82
Total Shareholders' Equity289K49.47M113.23M202.91M292.08M593.58M522.23M778.64M946.38M
Common Stock000000000
Retained Earnings-1.15M-9.07M-19.96M-39.05M-71.21M-140.78M-280.76M-269.83M-180.67M
Treasury Stock000000000
Accumulated OCI-2K-25K2K10K6K-163K-728K638K-190K
Minority Interest000000000

Cash Flow

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-1.31M-3.89M-9.45M-18.71M-26.08M-47.94M-100.57M-88.8M123.42M
Operating CF Margin %---9.2%-----1.75%0.42%
Operating CF Growth %--1.97%-1.43%-0.98%-0.39%-0.84%-1.1%0.12%2.39%
Net Income-1.15M-7.92M-10.89M-19.09M-32.17M-69.57M-139.97M10.93M89.16M
Depreciation & Amortization2K23K141K748K1.85M2.77M4.05M5.01M6.71M
Stock-Based Compensation33K246K792K1.24M3.27M15.32M33.23M39.93M49.13M
Deferred Taxes000000000
Other Non-Cash Items7K3.26M962K67K33K1.49M-690K-106.79M-7.12M
Working Capital Changes-203K498K511K-1.68M928K2.05M2.81M-37.88M-14.46M
Change in Receivables0000000-42.04M-62.71M
Change in Inventory0000000-4.47M-11.91M
Change in Payables42K133K112K-199K783K712K-1.25M-101K1.01M
Cash from Investing+-15K-210K-10.32M-4.97M-11.18M-226.77M-114.08M82.64M-163.44M
Capital Expenditures-15K-210K-2.23M-6.4M-14.84M-68.34M-52.98M-11.8M-4.24M
CapEx % of Revenue--2.18%----0.23%0.01%
Acquisitions---------
Investments---------
Other Investing0000000100M0
Cash from Financing+3.25M51.77M73.85M107.53M118.02M347.69M35.35M202.75M27.01M
Debt Issued (Net)---------
Equity Issued (Net)---------
Dividends Paid000000000
Share Repurchases---------
Other Financing00000-7.96M-649K-749K-5.39M
Net Change in Cash---------
Free Cash Flow+-1.33M-4.1M-11.68M-25.11M-40.93M-116.27M-153.55M-100.6M119.18M
FCF Margin %---11.37%-----1.98%0.41%
FCF Growth %--2.09%-1.85%-1.15%-0.63%-1.84%-0.32%0.34%2.18%
FCF per Share-0.31-0.76-1.04-1.58-2.18-5.24-6.02-3.634.01
FCF Conversion (FCF/Net Income)1.14x0.49x0.87x0.98x0.81x0.69x0.72x-8.12x1.38x
Interest Paid000000000
Taxes Paid000000005.67M

Key Ratios

Metric201620172018201920202021202220232024
Return on Equity (ROE)-397.92%-31.83%-13.39%-12.08%-13%-15.71%-25.09%1.68%10.34%
Return on Invested Capital (ROIC)--7780.43%-189.36%-117.38%-91.62%-34.63%-34.59%-20.63%9.5%
Gross Margin--86.27%----93.9%93.09%
Net Margin---1060.27%----21.56%30.69%
Debt / Equity6.38x--0.02x0.04x0.01x0.02x0.01x0.01x
Interest Coverage-163.29x-1.52x-11.60x---45.76x---
FCF Conversion1.14x0.49x0.87x0.98x0.81x0.69x0.72x-8.12x1.38x
Revenue Growth----100%----473.02%

Frequently Asked Questions

Valuation & Price

Krystal Biotech, Inc. (KRYS) has a price-to-earnings (P/E) ratio of 94.0x. This suggests investors expect higher future growth.

Growth & Financials

Krystal Biotech, Inc. (KRYS) reported $373.2M in revenue for fiscal year 2024.

Krystal Biotech, Inc. (KRYS) grew revenue by 473.0% over the past year. This is strong growth.

Yes, Krystal Biotech, Inc. (KRYS) is profitable, generating $198.9M in net income for fiscal year 2024 (30.7% net margin).

Dividend & Returns

Krystal Biotech, Inc. (KRYS) has a return on equity (ROE) of 10.3%. This is reasonable for most industries.

Krystal Biotech, Inc. (KRYS) generated $165.6M in free cash flow for fiscal year 2024. Positive FCF indicates the company can fund dividends, buybacks, or reinvestment.

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