| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| KRYSKrystal Biotech, Inc. | 8.18B | 282.01 | 94.00 | 473.02% | 53.3% | 17.48% | 1.46% | 0.01 |
| BMRNBioMarin Pharmaceutical Inc. | 10.58B | 55.07 | 24.92 | 17.97% | 16.82% | 8.59% | 4.49% | 0.11 |
| SRPTSarepta Therapeutics, Inc. | 2.23B | 21.31 | 9.11 | 52.97% | -11.25% | -20.57% | 0.88 | |
| RAREUltragenyx Pharmaceutical Inc. | 2.27B | 23.50 | -3.74 | 29.01% | -91.95% | -35.88% | 0.15 | |
| DYNDyne Therapeutics, Inc. | 2.7B | 16.42 | -4.87 | -61.26% | 0.04 | |||
| TVTXTravere Therapeutics, Inc. | 2.54B | 28.40 | -6.96 | 60.55% | -20.32% | -120.36% | 6.80 | |
| BEAMBeam Therapeutics Inc. | 3.25B | 32.05 | -7.00 | -83.18% | -7.44% | -42.92% | 0.22 | |
| SLNOSoleno Therapeutics, Inc. | 2.25B | 41.95 | -9.58 | -79.5% | -15.85% | 0.22 |
| Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 8.82M | 19.16M | 6.34M | 2.81M | 80M |
| Revenue Growth % | - | - | - | - | 1.17% | -0.67% | -0.56% | 27.52% |
| Cost of Goods Sold | 715K | 1.34M | 2.05M | 59.04M | 69.7M | 76.78M | 0 | 63.39M |
| COGS % of Revenue | - | - | - | 6.69% | 3.64% | 12.11% | - | 0.79% |
| Gross Profit | -715K | -1.34M | -2.05M | -50.22M | -50.54M | -70.44M | 2.81M | 16.61M |
| Gross Margin % | - | - | - | -5.69% | -2.64% | -11.11% | 1% | 0.21% |
| Gross Profit Growth % | - | -0.88% | -0.53% | -23.46% | -0.01% | -0.39% | 1.04% | 4.92% |
| Operating Expenses | 22.99M | 33.5M | 56.57M | 21.39M | 30.52M | 42.12M | 113.47M | 38.51M |
| OpEx % of Revenue | - | - | - | 2.42% | 1.59% | 6.64% | 40.45% | 0.48% |
| Selling, General & Admin | 4.5M | 8.31M | 13.14M | 21.39M | 30.52M | 41.69M | 41.67M | 36.45M |
| SG&A % of Revenue | - | - | - | 2.42% | 1.59% | 6.57% | 14.85% | 0.46% |
| Research & Development | 18.49M | 25.18M | 43.43M | 59.04M | 69.7M | 76.78M | 71.8M | 63.39M |
| R&D % of Revenue | - | - | - | 6.69% | 3.64% | 12.11% | 25.6% | 0.79% |
| Other Operating Expenses | 28K | 392K | 0 | -59.04M | -69.7M | -76.36M | 0 | -61.32M |
| Operating Income | -22.99M | -33.5M | -58.63M | -71.61M | -81.05M | -112.56M | -110.66M | -21.9M |
| Operating Margin % | - | - | - | -8.12% | -4.23% | -17.75% | -39.45% | -0.27% |
| Operating Income Growth % | - | -0.46% | -0.75% | -0.22% | -0.13% | -0.39% | 0.02% | 0.8% |
| EBITDA | -22.28M | -32.15M | -56.57M | -69.23M | -78.54M | -110.15M | -108.49M | -20.3M |
| EBITDA Margin % | - | - | - | -7.85% | -4.1% | -17.37% | -38.68% | -0.25% |
| EBITDA Growth % | - | -0.44% | -0.76% | -0.22% | -0.13% | -0.4% | 0.02% | 0.81% |
| D&A (Non-Cash Add-back) | 715K | 1.34M | 2.05M | 2.38M | 2.52M | 2.41M | 2.17M | 1.59M |
| EBIT | -22.99M | -33.5M | -82.68M | -71.61M | -81.05M | -112.13M | -110.66M | -19.83M |
| Net Interest Income | 0 | 0 | 1.51M | 792K | 207K | 0 | 0 | 0 |
| Interest Income | 0 | 0 | 1.51M | 792K | 207K | 0 | 0 | 0 |
| Interest Expense | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | 29K | 910K | -24.05M | 792K | 207K | 2.69M | 13.33M | 12.17M |
| Pretax Income | -22.96M | -32.59M | -82.68M | -70.82M | -80.85M | -109.87M | -97.33M | -9.72M |
| Pretax Margin % | - | - | - | -8.03% | -4.22% | -17.32% | -34.7% | -0.12% |
| Income Tax | -1K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 1% | 1% | 1% | 1% | 1% | 1% | 1% | 1% |
| Net Income | -22.96M | -32.59M | -82.68M | -70.82M | -80.85M | -109.87M | -97.33M | -9.72M |
| Net Margin % | - | - | - | -8.03% | -4.22% | -17.32% | -34.7% | -0.12% |
| Net Income Growth % | - | -0.42% | -1.54% | 0.14% | -0.14% | -0.36% | 0.11% | 0.9% |
| Net Income (Continuing) | -22.96M | -32.59M | -82.68M | -70.82M | -80.85M | -109.87M | -97.33M | -9.72M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -1.36 | -1.92 | -3.49 | -2.70 | -2.22 | -2.35 | -1.59 | -0.16 |
| EPS Growth % | - | -0.41% | -0.82% | 0.23% | 0.18% | -0.06% | 0.32% | 0.9% |
| EPS (Basic) | -1.36 | -1.92 | -3.49 | -2.70 | -2.22 | -2.35 | -1.59 | -0.16 |
| Diluted Shares Outstanding | 16.94M | 16.94M | 22.66M | 25.35M | 35.36M | 44.99M | 61.31M | 61.98M |
| Basic Shares Outstanding | 16.94M | 16.94M | 22.66M | 25.35M | 35.36M | 44.99M | 61.31M | 61.98M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - |
| Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 1.34M | 74.09M | 100.08M | 112.91M | 226M | 207.52M | 242.2M | 249.92M |
| Cash & Short-Term Investments | 407K | 72.8M | 96.71M | 112.91M | 218.16M | 202.92M | 236.22M | 241.02M |
| Cash Only | 407K | 72.8M | 96.71M | 57.05M | 35.41M | 35.1M | 25.56M | 58.21M |
| Short-Term Investments | 0 | 0 | 0 | 55.86M | 182.75M | 167.82M | 210.66M | 182.81M |
| Accounts Receivable | 39K | 501K | 111K | 2.71M | 4.11M | 1.08M | 2.25M | 3.34M |
| Days Sales Outstanding | - | - | - | 111.99 | 78.28 | 62.21 | 292.65 | 15.25 |
| Inventory | 734K | 559K | 2.98M | -2.78M | -473K | 0 | 0 | 0 |
| Days Inventory Outstanding | 374.7 | 151.7 | 528.92 | - | - | - | - | - |
| Other Current Assets | 248K | 238K | 284K | 74K | 0 | 0 | 0 | 0 |
| Total Non-Current Assets | 3M | 11.68M | 10.36M | 16.66M | 9M | 19.17M | 15.49M | 10.79M |
| Property, Plant & Equipment | 2.94M | 10.55M | 87.94M | 8.4M | 7.37M | 15.97M | 12.39M | 9.58M |
| Fixed Asset Turnover | - | - | - | 1.05x | 2.60x | 0.40x | 0.23x | 8.35x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 1.09M | 1.09M | 1.09M | 1.09M | 1.09M | 0 | 0 |
| Other Non-Current Assets | 60K | 38K | -78.68M | 7.17M | 542K | 2.1M | 3.1M | 1.21M |
| Total Assets | 4.34M | 85.77M | 110.44M | 129.58M | 235M | 226.69M | 257.69M | 260.72M |
| Asset Turnover | - | - | - | 0.07x | 0.08x | 0.03x | 0.01x | 0.31x |
| Asset Growth % | - | 18.76% | 0.29% | 0.17% | 0.81% | -0.04% | 0.14% | 0.01% |
| Total Current Liabilities | 2.79M | 4.23M | 12.14M | 26.73M | 19.2M | 16.73M | 13.68M | 11.04M |
| Accounts Payable | 1.67M | 1.26M | 2.19M | 4.08M | 4.79M | 3.64M | 2.76M | 1.16M |
| Days Payables Outstanding | 854.05 | 342.75 | 388.65 | 25.22 | 25.07 | 17.29 | - | 6.7 |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 2.6M | 0 | 0 |
| Deferred Revenue (Current) | 0 | 1000K | 1000K | 1000K | 1000K | 934K | 0 | 0 |
| Other Current Liabilities | 20K | 781K | 3.68M | 4.79M | 4.71M | 5.34M | 396K | 463K |
| Current Ratio | 0.48x | 17.52x | 8.24x | 4.23x | 11.77x | 12.41x | 17.71x | 22.63x |
| Quick Ratio | 0.22x | 17.39x | 8.00x | 4.33x | 11.80x | 12.41x | 17.71x | 22.63x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 233K | 5.54M | 11.15M | 7.67M | 4.26M | 11.02M | 8.83M | 6.64M |
| Long-Term Debt | 34.59M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 0 | 0 | 0 | 0 | 0 | 10.82M | 8.63M | 6.44M |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | -34.35M | 5.54M | 5.13M | 4.7M | 4.26M | 0 | 197K | 197K |
| Total Liabilities | 3.02M | 9.77M | 23.29M | 34.4M | 23.46M | 27.74M | 22.5M | 17.68M |
| Total Debt | 34.59M | 46K | 50K | 17K | 0 | 13.42M | 10.82M | 8.63M |
| Net Debt | 34.18M | -72.75M | -96.66M | -57.03M | -35.41M | -21.68M | -14.74M | -49.58M |
| Debt / Equity | 26.16x | 0.00x | 0.00x | 0.00x | - | 0.07x | 0.05x | 0.04x |
| Debt / EBITDA | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - |
| Interest Coverage | - | - | - | - | - | - | - | - |
| Total Equity | 1.32M | 76M | 87.15M | 95.18M | 211.54M | 198.94M | 235.19M | 243.03M |
| Equity Growth % | - | 56.49% | 0.15% | 0.09% | 1.22% | -0.06% | 0.18% | 0.03% |
| Book Value per Share | 0.08 | 4.49 | 3.85 | 3.75 | 5.98 | 4.42 | 3.84 | 3.92 |
| Total Shareholders' Equity | 1.32M | 76M | 87.15M | 95.18M | 211.54M | 198.94M | 235.19M | 243.03M |
| Common Stock | 1K | 16K | 23K | 28K | 41K | 52K | 62K | 54K |
| Retained Earnings | -35.54M | -68.12M | -150.8M | -221.62M | -302.47M | -412.34M | -509.67M | -519.4M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -893K | -1.96M | -110.44M | -2K | -397K | -797K | -136K | 130K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -20.07M | -22.56M | -39.48M | -53.66M | -78.48M | -97.05M | -90.97M | -2.22M |
| Operating CF Margin % | - | - | - | -6.08% | -4.1% | -15.3% | -32.43% | -0.03% |
| Operating CF Growth % | - | -0.12% | -0.75% | -0.36% | -0.46% | -0.24% | 0.06% | 0.98% |
| Net Income | -22.96M | -32.59M | -82.68M | -70.82M | -80.85M | -109.87M | -97.33M | -9.72M |
| Depreciation & Amortization | 715K | 1.34M | 2.05M | 2.38M | 2.52M | 2.41M | 2.17M | 1.59M |
| Stock-Based Compensation | 1.37M | 2.16M | 4.22M | 7.35M | 11.07M | 13.35M | 14.8M | 14.55M |
| Deferred Taxes | 0 | 0 | 0 | 1.93M | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 2.59M | 4.87M | 25.59M | -2M | 673K | 152K | -5.99M | -4.39M |
| Working Capital Changes | 804K | 6.52M | 11.33M | 7.5M | -11.89M | -3.09M | -4.61M | -4.25M |
| Change in Receivables | 0 | 0 | 0 | -2M | -500K | 2.5M | -308K | -1.56M |
| Change in Inventory | 0 | 0 | 0 | 229K | 1.25M | 0 | 0 | 0 |
| Change in Payables | 208K | -20K | 803K | 1.77M | 973K | -1.18M | -853K | -1.59M |
| Cash from Investing | -1.91M | -8.98M | -944K | -57.14M | -129.67M | 12.41M | -36.69M | 32.23M |
| Capital Expenditures | -1.91M | -8.98M | -853K | -1.34M | -1.71M | -1.96M | -508K | -278K |
| CapEx % of Revenue | - | - | - | 0.15% | 0.09% | 0.31% | 0.18% | 0% |
| Acquisitions | - | - | - | - | - | - | - | - |
| Investments | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | -91K | -55.8M | -127.96M | 14.38M | 0 | 0 |
| Cash from Financing | 17.66M | 105.03M | 64.34M | 71.13M | 186.51M | 84.32M | 118.12M | 2.75M |
| Debt Issued (Net) | - | - | - | - | - | - | - | - |
| Equity Issued (Net) | - | - | - | - | - | - | - | - |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | - | - | - | - | - | - | - | - |
| Other Financing | 17.66M | 12K | 249K | 1.24M | 3.67M | 3.52M | 777K | 0 |
| Net Change in Cash | - | - | - | - | - | - | - | - |
| Free Cash Flow | -21.98M | -31.54M | -40.34M | -55M | -80.19M | -99.01M | -91.47M | -2.5M |
| FCF Margin % | - | - | - | -6.23% | -4.18% | -15.61% | -32.61% | -0.03% |
| FCF Growth % | - | -0.43% | -0.28% | -0.36% | -0.46% | -0.23% | 0.08% | 0.97% |
| FCF per Share | -1.30 | -1.86 | -1.78 | -2.17 | -2.27 | -2.20 | -1.49 | -0.04 |
| FCF Conversion (FCF/Net Income) | 0.87x | 0.69x | 0.48x | 0.76x | 0.97x | 0.88x | 0.93x | 0.23x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Metric | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 |
|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -1737.07% | -84.29% | -101.35% | -77.68% | -52.72% | -53.53% | -44.84% | -4.07% |
| Return on Invested Capital (ROIC) | -48.57% | -129.67% | - | -375.11% | -56.74% | -47.78% | -41.74% | -7.94% |
| Gross Margin | - | - | - | -569.18% | -263.73% | -1110.69% | 100% | 20.77% |
| Net Margin | - | - | - | -802.66% | -421.89% | -1732.43% | -3470.05% | -12.16% |
| Debt / Equity | 26.16x | 0.00x | 0.00x | 0.00x | - | 0.07x | 0.05x | 0.04x |
| FCF Conversion | 0.87x | 0.69x | 0.48x | 0.76x | 0.97x | 0.88x | 0.93x | 0.23x |
| Revenue Growth | - | - | - | - | 117.19% | -66.91% | -55.77% | 2752.05% |
Fulcrum Therapeutics, Inc. (FULC) reported $80.0M in revenue for fiscal year 2024.
Fulcrum Therapeutics, Inc. (FULC) grew revenue by 2752.0% over the past year. This is strong growth.
Fulcrum Therapeutics, Inc. (FULC) reported a net loss of $71.1M for fiscal year 2024.
Fulcrum Therapeutics, Inc. (FULC) has a return on equity (ROE) of -4.1%. Negative ROE indicates the company is unprofitable.
Fulcrum Therapeutics, Inc. (FULC) had negative free cash flow of $60.4M in fiscal year 2024, likely due to heavy capital investments.