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Fulcrum Therapeutics, Inc. (FULC) 10-Year Financial Performance & Capital Metrics

FULC • • Industrial / General
HealthcareBiotechnologyRare Genetic DiseasesGene Therapy & Rare Diseases
AboutFulcrum Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing products for improving the lives of patients with genetically defined diseases in the areas of high unmet medical need in the United States. Its product candidates are losmapimod, a small molecule for the treatment of facioscapulohumeral muscular dystrophy; and FTX-6058, an investigational oral fetal hemoglobin inducer for the treatment of sickle cell disease and other hemoglobinopathies, including beta-thalassemia. The company is also discovering drug targets for the treatments of rare neuromuscular, muscular, central nervous system, and hematologic disorders, as well as cardiomyopathies and pulmonary diseases. Fulcrum Therapeutics, Inc. has research and discovery collaboration agreement with Acceleron Pharma Inc. to identify biological targets to modulate specific pathways associated with a targeted indication within the pulmonary disease space; and has a strategic collaboration and license agreement with MyoKardia, Inc. to discover, develop, and commercialize novel targeted therapies for the treatment of genetic cardiomyopathies. Fulcrum Therapeutics, Inc. was Incorporated in 2015 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue $80M +2752.0%
  • EBITDA -$20M +81.3%
  • Net Income -$10M +90.0%
  • EPS (Diluted) -0.16 +89.9%
  • Gross Margin 20.77% -79.2%
  • EBITDA Margin -25.38% +99.3%
  • Operating Margin -27.37% +99.3%
  • Net Margin -12.16% +99.6%
  • ROE -4.07% +90.9%
  • ROIC -7.94% +81.0%
  • Debt/Equity 0.04 -22.8%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Momentum leader: RS Rating 82 (top 18%)

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Low quality earnings: Net income not backed by cash flow
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y61.02%
TTM-100%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-297%

EPS CAGR

10Y-
5Y-
3Y-
TTM-280.65%

ROCE

10Y Avg-232.13%
5Y Avg-46.51%
3Y Avg-36.83%
Latest-8.87%

Peer Comparison

Gene Therapy & Rare Diseases
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Sector-Specific
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KRYSKrystal Biotech, Inc.8.18B282.0194.00473.02%53.3%17.48%1.46%0.01
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SRPTSarepta Therapeutics, Inc.2.23B21.319.1152.97%-11.25%-20.57%0.88
RAREUltragenyx Pharmaceutical Inc.2.27B23.50-3.7429.01%-91.95%-35.88%0.15
DYNDyne Therapeutics, Inc.2.7B16.42-4.87-61.26%0.04
TVTXTravere Therapeutics, Inc.2.54B28.40-6.9660.55%-20.32%-120.36%6.80
BEAMBeam Therapeutics Inc.3.25B32.05-7.00-83.18%-7.44%-42.92%0.22
SLNOSoleno Therapeutics, Inc.2.25B41.95-9.58-79.5%-15.85%0.22

Profit & Loss

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+0008.82M19.16M6.34M2.81M80M
Revenue Growth %----1.17%-0.67%-0.56%27.52%
Cost of Goods Sold+715K1.34M2.05M59.04M69.7M76.78M063.39M
COGS % of Revenue---6.69%3.64%12.11%-0.79%
Gross Profit+-715K-1.34M-2.05M-50.22M-50.54M-70.44M2.81M16.61M
Gross Margin %----5.69%-2.64%-11.11%1%0.21%
Gross Profit Growth %--0.88%-0.53%-23.46%-0.01%-0.39%1.04%4.92%
Operating Expenses+22.99M33.5M56.57M21.39M30.52M42.12M113.47M38.51M
OpEx % of Revenue---2.42%1.59%6.64%40.45%0.48%
Selling, General & Admin4.5M8.31M13.14M21.39M30.52M41.69M41.67M36.45M
SG&A % of Revenue---2.42%1.59%6.57%14.85%0.46%
Research & Development18.49M25.18M43.43M59.04M69.7M76.78M71.8M63.39M
R&D % of Revenue---6.69%3.64%12.11%25.6%0.79%
Other Operating Expenses28K392K0-59.04M-69.7M-76.36M0-61.32M
Operating Income+-22.99M-33.5M-58.63M-71.61M-81.05M-112.56M-110.66M-21.9M
Operating Margin %----8.12%-4.23%-17.75%-39.45%-0.27%
Operating Income Growth %--0.46%-0.75%-0.22%-0.13%-0.39%0.02%0.8%
EBITDA+-22.28M-32.15M-56.57M-69.23M-78.54M-110.15M-108.49M-20.3M
EBITDA Margin %----7.85%-4.1%-17.37%-38.68%-0.25%
EBITDA Growth %--0.44%-0.76%-0.22%-0.13%-0.4%0.02%0.81%
D&A (Non-Cash Add-back)715K1.34M2.05M2.38M2.52M2.41M2.17M1.59M
EBIT-22.99M-33.5M-82.68M-71.61M-81.05M-112.13M-110.66M-19.83M
Net Interest Income+001.51M792K207K000
Interest Income001.51M792K207K000
Interest Expense00000000
Other Income/Expense29K910K-24.05M792K207K2.69M13.33M12.17M
Pretax Income+-22.96M-32.59M-82.68M-70.82M-80.85M-109.87M-97.33M-9.72M
Pretax Margin %----8.03%-4.22%-17.32%-34.7%-0.12%
Income Tax+-1K0000000
Effective Tax Rate %1%1%1%1%1%1%1%1%
Net Income+-22.96M-32.59M-82.68M-70.82M-80.85M-109.87M-97.33M-9.72M
Net Margin %----8.03%-4.22%-17.32%-34.7%-0.12%
Net Income Growth %--0.42%-1.54%0.14%-0.14%-0.36%0.11%0.9%
Net Income (Continuing)-22.96M-32.59M-82.68M-70.82M-80.85M-109.87M-97.33M-9.72M
Discontinued Operations00000000
Minority Interest00000000
EPS (Diluted)+-1.36-1.92-3.49-2.70-2.22-2.35-1.59-0.16
EPS Growth %--0.41%-0.82%0.23%0.18%-0.06%0.32%0.9%
EPS (Basic)-1.36-1.92-3.49-2.70-2.22-2.35-1.59-0.16
Diluted Shares Outstanding16.94M16.94M22.66M25.35M35.36M44.99M61.31M61.98M
Basic Shares Outstanding16.94M16.94M22.66M25.35M35.36M44.99M61.31M61.98M
Dividend Payout Ratio--------

Balance Sheet

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+1.34M74.09M100.08M112.91M226M207.52M242.2M249.92M
Cash & Short-Term Investments407K72.8M96.71M112.91M218.16M202.92M236.22M241.02M
Cash Only407K72.8M96.71M57.05M35.41M35.1M25.56M58.21M
Short-Term Investments00055.86M182.75M167.82M210.66M182.81M
Accounts Receivable39K501K111K2.71M4.11M1.08M2.25M3.34M
Days Sales Outstanding---111.9978.2862.21292.6515.25
Inventory734K559K2.98M-2.78M-473K000
Days Inventory Outstanding374.7151.7528.92-----
Other Current Assets248K238K284K74K0000
Total Non-Current Assets+3M11.68M10.36M16.66M9M19.17M15.49M10.79M
Property, Plant & Equipment2.94M10.55M87.94M8.4M7.37M15.97M12.39M9.58M
Fixed Asset Turnover---1.05x2.60x0.40x0.23x8.35x
Goodwill00000000
Intangible Assets00000000
Long-Term Investments01.09M1.09M1.09M1.09M1.09M00
Other Non-Current Assets60K38K-78.68M7.17M542K2.1M3.1M1.21M
Total Assets+4.34M85.77M110.44M129.58M235M226.69M257.69M260.72M
Asset Turnover---0.07x0.08x0.03x0.01x0.31x
Asset Growth %-18.76%0.29%0.17%0.81%-0.04%0.14%0.01%
Total Current Liabilities+2.79M4.23M12.14M26.73M19.2M16.73M13.68M11.04M
Accounts Payable1.67M1.26M2.19M4.08M4.79M3.64M2.76M1.16M
Days Payables Outstanding854.05342.75388.6525.2225.0717.29-6.7
Short-Term Debt000002.6M00
Deferred Revenue (Current)01000K1000K1000K1000K934K00
Other Current Liabilities20K781K3.68M4.79M4.71M5.34M396K463K
Current Ratio0.48x17.52x8.24x4.23x11.77x12.41x17.71x22.63x
Quick Ratio0.22x17.39x8.00x4.33x11.80x12.41x17.71x22.63x
Cash Conversion Cycle--------
Total Non-Current Liabilities+233K5.54M11.15M7.67M4.26M11.02M8.83M6.64M
Long-Term Debt34.59M0000000
Capital Lease Obligations0000010.82M8.63M6.44M
Deferred Tax Liabilities00000000
Other Non-Current Liabilities-34.35M5.54M5.13M4.7M4.26M0197K197K
Total Liabilities3.02M9.77M23.29M34.4M23.46M27.74M22.5M17.68M
Total Debt+34.59M46K50K17K013.42M10.82M8.63M
Net Debt34.18M-72.75M-96.66M-57.03M-35.41M-21.68M-14.74M-49.58M
Debt / Equity26.16x0.00x0.00x0.00x-0.07x0.05x0.04x
Debt / EBITDA--------
Net Debt / EBITDA--------
Interest Coverage--------
Total Equity+1.32M76M87.15M95.18M211.54M198.94M235.19M243.03M
Equity Growth %-56.49%0.15%0.09%1.22%-0.06%0.18%0.03%
Book Value per Share0.084.493.853.755.984.423.843.92
Total Shareholders' Equity1.32M76M87.15M95.18M211.54M198.94M235.19M243.03M
Common Stock1K16K23K28K41K52K62K54K
Retained Earnings-35.54M-68.12M-150.8M-221.62M-302.47M-412.34M-509.67M-519.4M
Treasury Stock00000000
Accumulated OCI-893K-1.96M-110.44M-2K-397K-797K-136K130K
Minority Interest00000000

Cash Flow

Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-20.07M-22.56M-39.48M-53.66M-78.48M-97.05M-90.97M-2.22M
Operating CF Margin %----6.08%-4.1%-15.3%-32.43%-0.03%
Operating CF Growth %--0.12%-0.75%-0.36%-0.46%-0.24%0.06%0.98%
Net Income-22.96M-32.59M-82.68M-70.82M-80.85M-109.87M-97.33M-9.72M
Depreciation & Amortization715K1.34M2.05M2.38M2.52M2.41M2.17M1.59M
Stock-Based Compensation1.37M2.16M4.22M7.35M11.07M13.35M14.8M14.55M
Deferred Taxes0001.93M0000
Other Non-Cash Items2.59M4.87M25.59M-2M673K152K-5.99M-4.39M
Working Capital Changes804K6.52M11.33M7.5M-11.89M-3.09M-4.61M-4.25M
Change in Receivables000-2M-500K2.5M-308K-1.56M
Change in Inventory000229K1.25M000
Change in Payables208K-20K803K1.77M973K-1.18M-853K-1.59M
Cash from Investing+-1.91M-8.98M-944K-57.14M-129.67M12.41M-36.69M32.23M
Capital Expenditures-1.91M-8.98M-853K-1.34M-1.71M-1.96M-508K-278K
CapEx % of Revenue---0.15%0.09%0.31%0.18%0%
Acquisitions--------
Investments--------
Other Investing00-91K-55.8M-127.96M14.38M00
Cash from Financing+17.66M105.03M64.34M71.13M186.51M84.32M118.12M2.75M
Debt Issued (Net)--------
Equity Issued (Net)--------
Dividends Paid00000000
Share Repurchases--------
Other Financing17.66M12K249K1.24M3.67M3.52M777K0
Net Change in Cash--------
Free Cash Flow+-21.98M-31.54M-40.34M-55M-80.19M-99.01M-91.47M-2.5M
FCF Margin %----6.23%-4.18%-15.61%-32.61%-0.03%
FCF Growth %--0.43%-0.28%-0.36%-0.46%-0.23%0.08%0.97%
FCF per Share-1.30-1.86-1.78-2.17-2.27-2.20-1.49-0.04
FCF Conversion (FCF/Net Income)0.87x0.69x0.48x0.76x0.97x0.88x0.93x0.23x
Interest Paid00000000
Taxes Paid00000000

Key Ratios

Metric20172018201920202021202220232024
Return on Equity (ROE)-1737.07%-84.29%-101.35%-77.68%-52.72%-53.53%-44.84%-4.07%
Return on Invested Capital (ROIC)-48.57%-129.67%--375.11%-56.74%-47.78%-41.74%-7.94%
Gross Margin----569.18%-263.73%-1110.69%100%20.77%
Net Margin----802.66%-421.89%-1732.43%-3470.05%-12.16%
Debt / Equity26.16x0.00x0.00x0.00x-0.07x0.05x0.04x
FCF Conversion0.87x0.69x0.48x0.76x0.97x0.88x0.93x0.23x
Revenue Growth----117.19%-66.91%-55.77%2752.05%

Frequently Asked Questions

Growth & Financials

Fulcrum Therapeutics, Inc. (FULC) reported $80.0M in revenue for fiscal year 2024.

Fulcrum Therapeutics, Inc. (FULC) grew revenue by 2752.0% over the past year. This is strong growth.

Fulcrum Therapeutics, Inc. (FULC) reported a net loss of $71.1M for fiscal year 2024.

Dividend & Returns

Fulcrum Therapeutics, Inc. (FULC) has a return on equity (ROE) of -4.1%. Negative ROE indicates the company is unprofitable.

Fulcrum Therapeutics, Inc. (FULC) had negative free cash flow of $60.4M in fiscal year 2024, likely due to heavy capital investments.

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