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ANTXAN2 Therapeutics, Inc.
$5.11$140M
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ANTX logoAN2 Therapeutics, Inc.(ANTX)Earnings, Financials & Key Ratios

ANTX•NASDAQ
$5.11
Price updated Jun 27, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutAN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing treatments for rare, chronic, and serious infectious diseases. It is developing epetraborole, a once-daily oral treatment for patients with chronic non-tuberculous mycobacterial lung disease. The company was incorporated in 2017 and is headquartered in Menlo Park, California.Show more
  • Revenue$0
  • EBITDA-$38M
  • Net Income-$35M+31.5%
  • EPS (Diluted)-1.16+32.6%
  • ROE-52.14%-4.9%

ANTX Price & Volume

AN2 Therapeutics, Inc. (ANTX) stock price & volume — 10-year historical chart

Loading chart...

Clinical Stage Burn Threatens Future Operational Continuity

Investment Thesis • Updated 2026Q1

VerdictNegative
Growth:Contracting
Profitability:Negative
Financial Position:Vulnerable
Cash Flow:Burning
Primary Risk:Clinical and liquidity insolvency
"AN2 Therapeutics remains a pre-commercial biotechnology firm with zero revenue, leaving its valuation entirely dependent on the success of its boron-chemistry pipeline for non-tuberculous mycobacterial lung disease. The company faces significant liquidity risks as its cash position has dwindled to $19.9 million as of 2025Q4, necessitating potential dilutive capital raises to sustain ongoing clinical trials. Investors should monitor the firm's ability to manage its high R&D expenditure, which reached $14.7 million in 2024Q1, against its rapidly eroding asset base."

Verdict Logic

the company's cash position of $19.9 million as of 2025Q4 appears insufficient to support long-term clinical development without further dilutive financing.

ANTX Growth Metrics

AN2 Therapeutics, Inc. (ANTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM23.81%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM27.15%

Return on Capital

10 Years-146.98%
5 Years-58.59%
3 Years-57.51%
Last Year-56.42%

ANTX Recent Earnings

AN2 Therapeutics, Inc. (ANTX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)
Q2 2026Latest
May 11, 2026
Metric
Actual
Est
EPS
$0.29-26.1%
$0.23
Rev
—
—
Q2 2026
Mar 17, 2026
Metric
Actual
Est
EPS
$0.29-20.8%
$0.24
Rev
—
—
Q4 2025
Nov 12, 2025
Metric
Actual
Est
EPS
$0.31-34.8%
$0.23
Rev
—
—
Q3 2025
Aug 12, 2025
Metric
Actual
Est
EPS
$0.21+32.3%
$0.31
Rev
—
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 11, 2026
$0.29vs $0.23-26.1%
—
Q2 2026Mar 17, 2026
$0.29vs $0.24-20.8%
—
Q4 2025Nov 12, 2025
$0.31vs $0.23-34.8%
—
Q3 2025Aug 12, 2025
$0.21vs $0.31+32.3%
—
Based on last 12 quarters of dataView full earnings history →

Peers Comparison

Key metrics vs top competitors for AN2 Therapeutics, Inc. (ANTX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
ANTX logoANTXAN2 Therapeutics, Inc.Current
$5.11$140.02M-4.41——-52.14%—
INSM logoINSMInsmed Incorporated
$103.38$22.41B-16.1366.73%-144.44%-130.11%—
SPRO logoSPROSpero Therapeutics, Inc.
$2.26$130.86M15.0724.27%27.82%35.58%—
PRAX logoPRAXPraxis Precision Medicines, Inc.
$327.79$9.47B-24.32-100%—-43.02%—
ENTA logoENTAEnanta Pharmaceuticals, Inc.
$14.00$325.03M-3.65-3.42%-89.56%-64.04%—
IDYA logoIDYAIDEAYA Biosciences, Inc.
$36.74$3.23B-28.703024.43%-62.17%-13.96%—

Compare ANTX vs Peers

AN2 Therapeutics, Inc. (ANTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs INSM

Most directly comparable listed peer for ANTX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare ANTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs INSM, SPRO, PRAX, ENTA

ANTX SEC Filings & Documents

AN2 Therapeutics, Inc. (ANTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 11, 2026·SEC

Material company update

Apr 9, 2026·SEC

Material company update

Mar 20, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 25, 2025·SEC

FY 2024

Mar 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

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ANTX Frequently Asked Questions

AN2 Therapeutics, Inc. (ANTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is ANTX profitable?

AN2 Therapeutics, Inc. (ANTX) reported a net loss of $34.6M for fiscal year 2025.

Dividend & Returns
What is ANTX's return on equity?

AN2 Therapeutics, Inc. (ANTX) has a return on equity (ROE) of -52.1%. Negative ROE indicates the company is unprofitable.

What is AN2 Therapeutics, Inc.'s free cash flow?

AN2 Therapeutics, Inc. (ANTX) had negative free cash flow of $31.3M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in ANTX back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →