PolyPid Ltd.(PYPD)Earnings, Financials & Key Ratios
PYPD•NASDAQ
$4.44
$81M mkt cap·Price updated May 7, 2026
AboutPolyPid Ltd., a late-stage biopharma company, develops, manufactures, and commercializes products based on polymer-lipid encapsulation matrix (PLEX) platform to address unmet medical needs. Its lead product candidate is D-PLEX100, which is in Phase III clinical trial for the prevention of sternal (bone) surgical site infections (SSIs), as well as for the prevention of abdominal (soft tissue) SSIs. PolyPid Ltd. was incorporated in 2008 and is headquartered in Petah Tikva, Israel.Show more
- Revenue$0
- EBITDA-$31M-18.7%
- Net Income-$34M-17.7%
- EPS (Diluted)-2.09+57.4%
- ROE-366.29%+64.7%
- ROIC-547.81%+25.3%
- Debt/Equity0.25-79.6%
PYPD Key Insights
PolyPid Ltd. (PYPD) fundamental analysis — strengths, weaknesses & financial health based on data analysis
✓Strengths
No significant strengths identified
✗Weaknesses
- ✗Weak Piotroski F-Score: 3/9
- ✗Shares diluted 100.0% in last year
- ✗Low asset turnover indicates capital-intensive operations
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
PYPD Price & Volume
PolyPid Ltd. (PYPD) stock price & volume — 10-year historical chart
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PYPD Growth Metrics
PolyPid Ltd. (PYPD) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
Revenue CAGR
10 Years-
5 Years-
3 Years-
TTM-
Profit CAGR
10 Years-
5 Years-
3 Years-
TTM-43.18%
EPS CAGR
10 Years-
5 Years-
3 Years-
TTM91.97%
Return on Capital
10 Years-136.43%
5 Years-183.72%
3 Years-231.45%
Last Year-243.24%
PYPD Peer Comparison
PolyPid Ltd. (PYPD) competitors in Drug Delivery Technology Platforms — business model, growth, and fundamentals comparison
| Company | Market Cap | Stock Price | P/E Ratio (TTM) | Revenue Growth 1Y | Net Margin | Return on Equity (ROE) | FCF Yield | Debt / Equity |
|---|---|---|---|---|---|---|---|---|
 AGIO | 1.64B | 27.53 | -3.87 | 48.03% | -6.4% | -34.11% | 0.05 | |
 ACRS | 585.63M | 4.86 | -9.17 | -58.19% | -8.3% | -62.98% | ||
 HALO | 7.68B | 65.19 | 25.46 | 37.55% | 22.69% | 6.49% | ||
 CLDX | 2.22B | 33.32 | -8.54 | -78.63% | -172.53% | -41.68% | 0.00 | |
 NKTR | 1.69B | 83.37 | -8.57 | -43.89% | -297.07% | -399.1% | 1.66 | |
 MRK | 277.34B | 112.29 | 15.42 | 1.18% | 28.12% | 36.14% | 0.96 | |
 PFE | 150.63B | 26.48 | 19.47 | -1.65% | 11.83% | 8.34% | 0.78 | |
 BMY | 114.85B | 56.25 | 16.30 | -0.22% | 15.01% | 38.96% | 2.55 |
Compare PYPD vs Peers
PolyPid Ltd. (PYPD) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
PYPD Income Statement
PolyPid Ltd. (PYPD) annual income statement — 10-year revenue, gross profit & net income history
10Y historyFree accessUpdated daily
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Revenue Growth % | - | - | - | - | - | - | - | - | - |
| Cost of Goods Sold | 205K | 411K | 947K | 1.01M | 1.12M | 1.72M | 0 | 0 | 0 |
| COGS % of Revenue | - | - | - | - | - | - | - | - | - |
| Gross Profit | -205K▲ 0% | -411K▼ 100.5% | -947K▼ 130.4% | -1.01M▼ 6.9% | -1.12M▼ 10.5% | -1.72M▼ 53.9% | 0▲ 100.0% | 0▲ 0% | 0▲ 0% |
| Gross Margin % | - | - | - | - | - | - | - | - | - |
| Gross Profit Growth % | -61.42% | -100.49% | -130.41% | -6.86% | -10.47% | -53.94% | 100% | - | - |
| Operating Expenses | 13.8M | 18.36M | 17.61M | 25.26M | 42.03M | 37.17M | 22.87M | 28.03M | 32.97M |
| OpEx % of Revenue | - | - | - | - | - | - | - | - | - |
| Selling, General & Admin | 4.06M | 5.81M | 3.53M | 9.32M | 12.45M | 10.9M | 6.72M | 5.22M | 9.16M |
| SG&A % of Revenue | - | - | - | - | - | - | - | - | - |
| Research & Development | 9.74M | 12.55M | 14.08M | 16.95M | 30.42M | 27.99M | 16.15M | 22.81M | 23.81M |
| R&D % of Revenue | - | - | - | - | - | - | - | - | - |
| Other Operating Expenses | 0 | 0 | 0 | -1.01M | -848K | -1.72M | 0 | 0 | 0 |
| Operating Income | -13.8M▲ 0% | -18.36M▼ 33.1% | -18.56M▼ 1.1% | -26.27M▼ 41.6% | -43.15M▼ 64.2% | -38.89M▲ 9.9% | -22.87M▲ 41.2% | -28.03M▼ 22.6% | -32.97M▼ 17.6% |
| Operating Margin % | - | - | - | - | - | - | - | - | - |
| Operating Income Growth % | -34.52% | -33.07% | -1.07% | -41.55% | -64.22% | 9.87% | 41.2% | -22.57% | -17.62% |
| EBITDA | -13.6M | -17.95M | -17.61M | -25.26M | -42.03M | -37.17M | -21.05M | -26.41M | -31.34M |
| EBITDA Margin % | - | - | - | - | - | - | - | - | - |
| EBITDA Growth % | -34.18% | -32.06% | 1.89% | -43.42% | -66.38% | 11.56% | 43.38% | -25.48% | -18.7% |
| D&A (Non-Cash Add-back) | 205K | 411K | 947K | 1.01M | 1.12M | 1.72M | 1.82M | 1.62M | 1.62M |
| EBIT | -54.47M | 5.96M | -6.89M | -36.87M | -42.6M | -38.09M | -22.87M | -28.03M | -32.97M |
| Net Interest Income | 74K | 84K | 45K | 457K | 468K | -1.07M | -1.16M | -1.08M | -685K |
| Interest Income | 90K | 126K | 60K | 474K | 468K | 267K | 548K | 442K | 0 |
| Interest Expense | 16K | 42K | 15K | 17K | 0 | 1.34M | 1.71M | 1.52M | 0 |
| Other Income/Expense | -40.69M | 24.28M | 11.65M | -10.6M | 544K | -540K | -929K | -951K | -1.2M |
| Pretax Income | -54.49M▲ 0% | 5.92M▲ 110.9% | -6.91M▼ 216.7% | -36.87M▼ 433.9% | -42.6M▼ 15.5% | -39.43M▲ 7.4% | -23.8M▲ 39.6% | -28.98M▼ 21.8% | -34.16M▼ 17.9% |
| Pretax Margin % | - | - | - | - | - | - | - | - | - |
| Income Tax | 0 | 0 | 0 | 0 | 0 | 129K | 69K | 42K | 5K |
| Effective Tax Rate % | 0% | 0% | 0% | 0% | 0% | -0.33% | -0.29% | -0.14% | -0.01% |
| Net Income | -54.49M▲ 0% | 5.92M▲ 110.9% | -6.91M▼ 216.7% | -35.32M▼ 411.6% | -40.71M▼ 15.3% | -39.52M▲ 2.9% | -23.86M▲ 39.6% | -29.02M▼ 21.6% | -34.17M▼ 17.7% |
| Net Margin % | - | - | - | - | - | - | - | - | - |
| Net Income Growth % | -378.3% | 110.86% | -216.7% | -411.57% | -15.26% | 2.92% | 39.62% | -21.61% | -17.73% |
| Net Income (Continuing) | -54.49M | 5.92M | -6.91M | -36.87M | -42.6M | -39.56M | -23.86M | -29.02M | -34.17M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -370.58▲ 0% | 26.70▲ 107.2% | 21.44▼ 19.7% | -122.10▼ 669.5% | -67.80▲ 44.5% | -61.20▲ 9.7% | -16.99▲ 72.2% | -4.91▲ 71.1% | -2.09▲ 57.4% |
| EPS Growth % | -378.29% | 107.2% | -19.7% | -669.5% | 44.47% | 9.73% | 72.24% | 71.1% | 57.43% |
| EPS (Basic) | -370.58 | 26.70 | 21.44 | -4.48 | -67.80 | -61.20 | -16.99 | -4.91 | -2.09 |
| Diluted Shares Outstanding | 588.15K | 886.43K | 886.43K | 1.28M | 1.25M | 1.3M | 1.4M | 5.91M | 16.35M |
| Basic Shares Outstanding | 588.15K | 886.43K | 886.43K | 1.28M | 1.25M | 1.3M | 1.4M | 5.91M | 16.35M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
PYPD Balance Sheet
PolyPid Ltd. (PYPD) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 18.73M | 8.03M | 27.41M | 47.2M | 34.81M | 14.19M | 6.07M | 16.57M | 15.23M |
| Cash & Short-Term Investments | 17.94M | 7.33M | 26.62M | 44.48M | 32.2M | 12.59M | 5.61M | 15.64M | 12.93M |
| Cash Only | 3.91M | 7.33M | 3.94M | 4.32M | 9.82M | 8.55M | 5.61M | 15.64M | 6.4M |
| Short-Term Investments | 14.03M | 0 | 22.68M | 40.16M | 22.38M | 4.04M | 0 | 0 | 6.53M |
| Accounts Receivable | 28K | 24K | 18K | 139K | 118K | 298K | 0 | 0 | 0 |
| Days Sales Outstanding | - | - | - | - | - | - | - | - | - |
| Inventory | 0 | -24K | 351K | 0 | 0 | 0 | 0 | 0 | 1.11M |
| Days Inventory Outstanding | - | - | 135.29 | - | - | - | - | - | - |
| Other Current Assets | 459K | 211K | 243K | 673K | 993K | 750K | 106K | 602K | 193K |
| Total Non-Current Assets | 4.25M | 6.45M | 6.35M | 28.65M | 9.42M | 11.78M | 9.3M | 8.65M | 7.08M |
| Property, Plant & Equipment | 2.93M | 6.19M | 6.12M | 5.89M | 8.76M | 11.68M | 9.22M | 8.37M | 6.77M |
| Fixed Asset Turnover | - | - | - | - | - | - | - | - | - |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Long-Term Investments | 0 | 219K | 199K | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Assets | 1.33M | 42K | 31K | 22.76M | 663K | 99K | 87K | 277K | 311K |
| Total Assets | 22.98M▲ 0% | 14.48M▼ 37.0% | 33.77M▲ 133.1% | 75.85M▲ 124.6% | 44.23M▼ 41.7% | 25.97M▼ 41.3% | 15.37M▼ 40.8% | 25.22M▲ 64.1% | 22.31M▼ 11.6% |
| Asset Turnover | - | - | - | - | - | - | - | - | - |
| Asset Growth % | 19.48% | -36.98% | 133.12% | 124.63% | -41.68% | -41.29% | -40.81% | 64.06% | -11.55% |
| Total Current Liabilities | 3.36M | 3.69M | 2.58M | 2.88M | 8.08M | 8.55M | 7.29M | 12.68M | 7.74M |
| Accounts Payable | 2.02M | 1.13M | 1.58M | 974K | 4.14M | 1.14M | 772K | 2.41M | 2.86M |
| Days Payables Outstanding | 3.59K | 1.01K | 609.36 | 351.29 | 1.35K | 241.99 | - | - | - |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 4.02M | 4M | 6.79M | 988K |
| Deferred Revenue (Current) | 0 | 0 | 0 | 241K | 269K | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 0 | 1.65M | 319K | 0 | 0 | 16K | 1.01M | 23K | 0 |
| Current Ratio | 5.57x | 2.18x | 10.63x | 16.41x | 4.31x | 1.66x | 0.83x | 1.31x | 1.97x |
| Quick Ratio | 5.57x | 2.18x | 10.49x | 16.41x | 4.31x | 1.66x | 0.83x | 1.31x | 1.82x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 108.27M | 92.5M | 251K | 193K | 199K | 11.59M | 10.18M | 4.86M | 3.6M |
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 7.57M | 6.38M | 634K | 0 |
| Capital Lease Obligations | 0 | 0 | 0 | 0 | 0 | 1.17M | 857K | 1.28M | 647K |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 107.67M | 92.5M | 251K | 193K | 199K | 294K | 398K | 396K | 2.95M |
| Total Liabilities | 111.63M | 96.19M | 2.83M | 3.07M | 8.28M | 20.14M | 17.47M | 17.54M | 11.33M |
| Total Debt | 0 | 0 | 0 | 0 | 0 | 13.73M | 11.78M | 9.62M | 2.8M |
| Net Debt | -3.91M | -7.33M | -3.94M | -4.32M | -9.82M | 5.18M | 6.17M | -6.02M | -3.61M |
| Debt / Equity | - | - | - | - | - | 2.36x | - | 1.25x | 0.25x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Interest Coverage | -862.50x | -437.24x | -1237.33x | -1545.41x | - | -29.04x | -13.36x | -18.38x | - |
| Total Equity | -88.65M▲ 0% | -81.71M▲ 7.8% | 30.93M▲ 137.9% | 72.78M▲ 135.3% | 35.96M▼ 50.6% | 5.83M▼ 83.8% | -2.1M▼ 136.0% | 7.68M▲ 466.6% | 10.97M▲ 42.8% |
| Equity Growth % | -161.04% | 7.82% | 137.86% | 135.26% | -50.59% | -83.79% | -135.96% | 466.6% | 42.8% |
| Book Value per Share | -150.72 | -92.18 | 34.90 | 56.96 | 28.81 | 4.50 | -1.49 | 1.30 | 0.67 |
| Total Shareholders' Equity | -88.65M | -81.71M | 30.93M | 72.78M | 35.96M | 5.83M | -2.1M | 7.68M | 10.97M |
| Common Stock | 129K | 130K | 130K | 0 | 0 | 0 | 0 | 0 | 0 |
| Retained Earnings | -92.31M | -86.4M | -93.3M | -132.29M | -174.89M | -214.44M | -238.31M | -267.33M | -301.5M |
| Treasury Stock | -3.54M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -766K | -1.18M | -2.12M | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
PYPD Cash Flow Statement
PolyPid Ltd. (PYPD) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -12.31M | -16.68M | -17.36M | -21.6M | -32.39M | -34.32M | -17.24M | -21.96M | 0 |
| Operating CF Margin % | - | - | - | - | - | - | - | - | - |
| Operating CF Growth % | -26.5% | -35.46% | -4.08% | -24.42% | -49.96% | -5.96% | 49.77% | -27.43% | 100% |
| Net Income | -54.49M | 5.92M | -6.91M | -36.87M | -42.6M | -39.56M | -23.86M | -29.02M | -34.17M |
| Depreciation & Amortization | 205K | 411K | 947K | 1.01M | 1.12M | 1.72M | 1.82M | 1.62M | 0 |
| Stock-Based Compensation | 1.38M | 995K | 976K | 4.58M | 4.75M | 4.31M | 3.39M | 2.82M | 0 |
| Deferred Taxes | 0 | 0 | 0 | 0 | -4.64M | 0 | -201K | 0 | 0 |
| Other Non-Cash Items | 40.78M | -24.47M | -11.37M | 11.37M | 4.64M | 289K | 1.73M | 697K | 34.17M |
| Working Capital Changes | -187K | 472K | -1.01M | -1.69M | 4.35M | -1.08M | -110K | 1.92M | 0 |
| Change in Receivables | 0 | 0 | 0 | -1.92M | 123K | 0 | 0 | 0 | 0 |
| Change in Inventory | 0 | 0 | 0 | 1.92M | -123K | 0 | 0 | 0 | 0 |
| Change in Payables | 385K | -887K | 449K | -607K | 2.22M | -3.1M | -369K | 1.64M | 0 |
| Cash from Investing | -8.38M | 10.96M | -23.56M | -40.77M | 36.9M | 16.57M | 3.8M | -330K | 0 |
| Capital Expenditures | -1.88M | -3.07M | -879K | -1.18M | -2.99M | -1.77M | -196K | -76K | 0 |
| CapEx % of Revenue | - | - | - | - | - | - | - | - | - |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | -6.5M | 14.03M | 0 | 0 | 8M | 7M | 0 | 0 | 0 |
| Cash from Financing | 14.38M | 9.39M | 37.65M | 62.77M | 1.03M | 16.43M | 9.98M | 32.42M | 0 |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 11.31M | -2.62M | -3.32M | 0 |
| Equity Issued (Net) | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Financing | 68K | 24K | 7K | 17K | 0 | 696K | 3.87M | -125K | 0 |
| Net Change in Cash | -6.31M▲ 0% | 3.67M▲ 158.1% | -3.27M▼ 189.1% | 410K▲ 112.5% | 5.55M▲ 1253.2% | -1.31M▼ 123.7% | -3.46M▼ 163.0% | 10.12M▲ 392.9% | -15.81M▼ 256.2% |
| Free Cash Flow | -14.2M▲ 0% | -19.75M▼ 39.1% | -18.24M▲ 7.7% | -22.77M▼ 24.9% | -35.38M▼ 55.4% | -36.08M▼ 2.0% | -17.43M▲ 51.7% | -22.04M▼ 26.4% | 0▲ 100.0% |
| FCF Margin % | - | - | - | - | - | - | - | - | - |
| FCF Growth % | -38.2% | -39.14% | 7.67% | -24.87% | -55.36% | -1.99% | 51.69% | -26.43% | 100% |
| FCF per Share | -24.14 | -22.28 | -20.57 | -17.82 | -28.35 | -27.86 | -12.41 | -3.73 | - |
| FCF Conversion (FCF/Net Income) | 0.23x | -2.82x | 2.51x | 0.61x | 0.80x | 0.87x | 0.72x | 0.76x | - |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 734K | 1.04M | 950K | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 8K | 18K | 3K | 0 |
PYPD Key Ratios
PolyPid Ltd. (PYPD) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | - | - | - | -22.32% | -68.12% | -74.88% | -189.16% | -1278.6% | -1038.73% | -366.29% |
| Return on Invested Capital (ROIC) | - | - | - | - | -41.28% | -68.41% | -157.03% | -227.44% | -733.23% | -547.81% |
| Debt / Equity | - | - | - | - | - | - | 2.36x | - | 1.25x | 0.25x |
| Interest Coverage | -94.99x | -862.50x | -437.24x | -1237.33x | -1545.41x | - | -29.04x | -13.36x | -18.38x | - |
| FCF Conversion | 0.85x | 0.23x | -2.82x | 2.51x | 0.61x | 0.80x | 0.87x | 0.72x | 0.76x | - |
PYPD Frequently Asked Questions
PolyPid Ltd. (PYPD) stock FAQ — growth, dividends, profitability & financials explained
Growth & Financials
PolyPid Ltd. (PYPD) grew revenue by 0.0% over the past year. Growth has been modest.
PolyPid Ltd. (PYPD) reported a net loss of $34.2M for fiscal year 2025.
Dividend & Returns
PolyPid Ltd. (PYPD) has a return on equity (ROE) of -366.3%. Negative ROE indicates the company is unprofitable.
Explore More PYPD
PolyPid Ltd. (PYPD) financial analysis — history, returns, DCA and operating performance tools
Total Return Calculator
Historical returns with dividends reinvested
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Dividend History
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Earnings History
EPS trends, net income & profitability
Price History
Long-term charts & historical price data
Revenue History
Sales growth patterns & revenue breakdown
Financial Ratios
30 years of market, efficiency and balance-sheet ratios
Valuation
DCF intrinsic value, peer multiples & estimates