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ANTX logoAN2 Therapeutics, Inc.(ANTX)Earnings, Financials & Key Ratios

ANTX•NASDAQ
Price updated Jun 11, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutAN2 Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing treatments for rare, chronic, and serious infectious diseases. It is developing epetraborole, a once-daily oral treatment for patients with chronic non-tuberculous mycobacterial lung disease. The company was incorporated in 2017 and is headquartered in Menlo Park, California.Show more
  • Revenue$0
  • EBITDA-$38M
  • Net Income-$35M+31.5%
  • EPS (Diluted)-1.16+32.6%
  • ROE-52.14%-4.9%
  • ROIC-61.06%-26.5%

ANTX Key Insights

AN2 Therapeutics, Inc. (ANTX) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 97 (top 3%)

✗Weaknesses

  • ✗Profits declining 20.9% over 5 years
  • ✗Weak Piotroski F-Score: 1/9
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ANTX Price & Volume

AN2 Therapeutics, Inc. (ANTX) stock price & volume — 10-year historical chart

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ANTX Growth Metrics

AN2 Therapeutics, Inc. (ANTX) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM23.81%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM27.15%

Return on Capital

10 Years-146.98%
5 Years-58.59%
3 Years-57.51%
Last Year-56.42%

ANTX Recent Earnings

AN2 Therapeutics, Inc. (ANTX) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 5/12 qtrs (42%)
Q2 2026Latest
May 11, 2026
EPS
$0.29
Est $0.23
-26.1%
Revenue
—
Q2 2026
Mar 17, 2026
EPS
$0.29
Est $0.24
-20.8%
Revenue
—
Q4 2025
Nov 12, 2025
EPS
$0.31
Est $0.23
-34.8%
Revenue
—
Q3 2025
Aug 12, 2025
EPS
$0.21
Est $0.31
+32.3%
Revenue
—
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 11, 2026
$0.29vs $0.23-26.1%
—
Q2 2026Mar 17, 2026
$0.29vs $0.24-20.8%
—
Q4 2025Nov 12, 2025
$0.31vs $0.23-34.8%
—
Q3 2025Aug 12, 2025
$0.21vs $0.31+32.3%
—
Based on last 12 quarters of dataView full earnings history →

ANTX Peer Comparison

AN2 Therapeutics, Inc. (ANTX) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
INSM logoINSMInsmed IncorporatedDirect Competitor20.96B96.72-15.0966.73%-144.44%-130.11%1.04
SPRO logoSPROSpero Therapeutics, Inc.Direct Competitor156.33M2.701824.27%27.82%35.58%0.05
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor7.16B247.98-18.40-100%-43.02%0.00
ENTA logoENTAEnanta Pharmaceuticals, Inc.Product Competitor267.22M11.51-3.00-3.42%-89.56%-64.04%3.11
IDYA logoIDYAIDEAYA Biosciences, Inc.Product Competitor2.53B28.84-22.5330.24%-62.17%-13.96%0.03
TARS logoTARSTarsus Pharmaceuticals, Inc.Product Competitor2.69B62.61-39.38146.71%-9.02%-14.19%0.27
NKTR logoNKTRNektar TherapeuticsProduct Competitor1.16B59.21-6.09-43.89%-284.18%-87%1.66
CRL logoCRLCharles River Laboratories International, Inc.Supply Chain9.06B188.06-64.63-0.85%-4.59%-5.66%0.95

Compare ANTX vs Peers

AN2 Therapeutics, Inc. (ANTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs INSM

Most directly comparable listed peer for ANTX.

Scale Benchmark

vs MRK

Larger-name benchmark to compare ANTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs INSM, SPRO, PRAX, ENTA

ANTX Income Statement

AN2 Therapeutics, Inc. (ANTX) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
00000000
Revenue Growth %
--------
Cost of Goods Sold
00077K0000
COGS % of Revenue
--------
Gross Profit
0▲ 0%
0▲ 0%
0▲ 0%
-77K▲ 0%
0▲ 100.0%
0▲ 0%
0▲ 0%
0▲ 0%
Gross Margin %
--------
Gross Profit Growth %
----100%---
Operating Expenses
31.07M7.28M21.57M42.19M69.64M54.55M38.11M37.12M
OpEx % of Revenue
--------
Selling, General & Admin
1.73M1.26M4.67M12.75M14.76M14.07M13.34M13.3M
SG&A % of Revenue
--------
Research & Development
29.33M6.02M16.91M29.51M54.87M40.49M24.77M23.82M
R&D % of Revenue
--------
Other Operating Expenses
00000000
Operating Income
-31.07M▲ 0%
-7.28M▲ 76.6%
-21.57M▼ 196.2%
-42.26M▼ 95.9%
-69.64M▼ 64.8%
-54.55M▲ 21.7%
-38.11M▲ 30.1%
-37.12M▲ 0%
Operating Margin %
--------
Operating Income Growth %
-76.55%-196.18%-95.89%-64.77%21.66%30.14%-
EBITDA
00-21.57M-42.19M00-38.11M-36.6M
EBITDA Margin %
--------
EBITDA Growth %
----95.54%100%---165.78%
D&A (Non-Cash Add-back)
31.07M7.28M077K69.64M54.55M00
EBIT
-31.07M-13.6M-21.57M-40.96M-64.73M-51.32M-38.11M-36.6M
Net Interest Income
03K69K837K05.47M2.93M2.57M
Interest Income
03K69K1.35M05.47M2.93M2.57M
Interest Expense
000514K0000
Other Income/Expense
-2.74M-6.32M31K1.31M4.9M3.23M2.94M2.57M
Pretax Income
-33.81M▲ 0%
-13.6M▲ 59.8%
-21.54M▼ 58.4%
-40.96M▼ 90.1%
-64.73M▼ 58.1%
-51.32M▲ 20.7%
-35.17M▲ 31.5%
-34.55M▲ 0%
Pretax Margin %
--------
Income Tax
00000000
Effective Tax Rate %
0%0%0%0%0%0%0%0%
Net Income
-33.81M▲ 0%
-13.6M▲ 59.8%
-21.54M▼ 58.4%
-40.96M▼ 90.1%
-64.73M▼ 58.1%
-51.32M▲ 20.7%
-35.17M▲ 31.5%
-34.55M▲ 0%
Net Margin %
--------
Net Income Growth %
-59.77%-58.37%-90.11%-58.05%20.72%31.46%23.81%
Net Income (Continuing)
-33.81M-13.6M-21.54M-40.96M-64.73M-51.32M-35.17M-34.55M
Discontinued Operations
00000000
Minority Interest
00000000
EPS (Diluted)
-0.30▲ 0%
-0.78▼ 160.0%
-1.50▼ 92.3%
-2.79▼ 86.0%
-2.74▲ 1.8%
-1.72▲ 37.2%
-1.16▲ 32.6%
-1.01▲ 0%
EPS Growth %
--160%-92.31%-86%1.79%37.23%32.56%27.15%
EPS (Basic)
-0.30-0.78-1.50-2.79-2.74-1.72-1.16-
Diluted Shares Outstanding
18.74M18.74M18.74M15.34M23.6M29.83M30.22M34.06M
Basic Shares Outstanding
18.74M18.74M18.74M15.34M23.6M29.83M30.22M34.06M
Dividend Payout Ratio
--------

ANTX Balance Sheet

AN2 Therapeutics, Inc. (ANTX) balance sheet — assets, liabilities & shareholders' equity

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
5.7M4.23M60.11M98.62M110.51M86.26M59.94M87.49M
Cash & Short-Term Investments
5.6M4.07M58.55M96.06M107.3M83.62M58M85.29M
Cash Only
5.6M4.07M12.1M27.22M15.65M21.35M19.94M53.49M
Short-Term Investments
0046.46M68.84M91.65M62.27M38.06M31.8M
Accounts Receivable
00001.4M300K900K0
Days Sales Outstanding
--------
Inventory
00000000
Days Inventory Outstanding
--------
Other Current Assets
82K002.56M02.34M1.04M2.2M
Total Non-Current Assets
005.21M3.94M28.24M5.83M2.01M0
Property, Plant & Equipment
00053K0000
Fixed Asset Turnover
--------
Goodwill
00000000
Intangible Assets
00000000
Long-Term Investments
003.49M3.22M27.19M5.02M2.01M13.53M
Other Non-Current Assets
001.72M667K1.04M804K00
Total Assets
5.7M▲ 0%
4.23M▼ 25.7%
65.32M▲ 1442.7%
102.56M▲ 57.0%
138.74M▲ 35.3%
92.09M▼ 33.6%
61.95M▼ 32.7%
87.49M▲ 0%
Asset Turnover
-------0.00x
Asset Growth %
--25.72%1442.65%57.02%35.28%-33.63%-32.73%-86.45%
Total Current Liabilities
159K1.46M3.4M7.19M14.04M10.24M8.72M5.56M
Accounts Payable
51K132K1.06M2.12M2.68M3.32M3.02M2.62M
Days Payables Outstanding
---10.06K----
Short-Term Debt
00000000
Deferred Revenue (Current)
00000000
Other Current Liabilities
014K330K6K4.69M2.47M5.7M2.95M
Current Ratio
35.85x2.90x17.70x13.72x7.87x8.43x6.87x15.73x
Quick Ratio
35.85x2.90x17.70x13.72x7.87x8.43x6.87x15.73x
Cash Conversion Cycle
--------
Total Non-Current Liabilities
728K24K13K2K00170K170K
Long-Term Debt
728K0000000
Capital Lease Obligations
00000000
Deferred Tax Liabilities
00000000
Other Non-Current Liabilities
024K13K2K00170K170K
Total Liabilities
887K1.48M3.41M7.19M14.04M10.24M8.89M5.73M
Total Debt
728K0053K0000
Net Debt
-4.87M-4.07M-12.1M-27.17M-15.65M-21.35M-19.94M-53.49M
Debt / Equity
0.15x--0.00x---0.00x
Debt / EBITDA
--------0.00x
Net Debt / EBITDA
-------1.46x
Interest Coverage
----79.68x----
Total Equity
4.81M▲ 0%
2.75M▼ 42.8%
61.91M▲ 2150.4%
95.37M▲ 54.1%
124.7M▲ 30.8%
81.85M▼ 34.4%
53.06M▼ 35.2%
81.76M▲ 0%
Equity Growth %
--42.84%2150.38%54.05%30.75%-34.36%-35.17%-84.82%
Book Value per Share
0.260.153.306.225.282.741.762.40
Total Shareholders' Equity
4.81M2.75M61.91M95.37M124.7M81.85M53.06M81.76M
Common Stock
00000000
Retained Earnings
-5.8M-20.32M-47.38M-89.72M-154.46M-205.78M-240.95M-250.98M
Treasury Stock
00000000
Accumulated OCI
00-27K-374K275K31K57K-5K
Minority Interest
00000000

ANTX Cash Flow Statement

AN2 Therapeutics, Inc. (ANTX) cash flow — operating, investing & free cash flow history

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-2.49M-5.36M-20.48M-33.46M-53.29M-49.26M-29.83M-31.28M
Operating CF Margin %
--------
Operating CF Growth %
--115.77%-281.88%-63.36%-59.25%7.56%39.43%81.14%
Net Income
-5.63M-13.6M-21.54M-40.96M-64.73M-51.32M-35.17M-34.55M
Depreciation & Amortization
00000000
Stock-Based Compensation
040K974K4.39M8.41M8.34M6.25M4.2M
Deferred Taxes
00000000
Other Non-Cash Items
3.16M6.97M53K-615K-2.8M-3.28M-1.07M752K
Working Capital Changes
-10K1.22M32K3.72M5.83M-3M164K-1.68M
Change in Receivables
00000000
Change in Inventory
00000000
Change in Payables
-16K81K417K2.5M553K641K-296K-457K
Cash from Investing
00-50.02M-21.77M-43.28M54.59M28.31M27.41M
Capital Expenditures
00000000
CapEx % of Revenue
--------
Acquisitions
00000000
Investments
--------
Other Investing
00000000
Cash from Financing
8.08M3.84M78.53M70.36M84.99M372K113K37.38M
Debt Issued (Net)
00000000
Equity Issued (Net)
8.08M3.77M79.73M70.37M84.53M372K113K37.38M
Dividends Paid
00000000
Share Repurchases
00000000
Other Financing
064K-1.2M-11K465K000
Net Change in Cash
5.6M▲ 0%
-1.53M▼ 127.3%
8.03M▲ 625.3%
15.12M▲ 88.4%
-11.57M▼ 176.5%
5.7M▲ 149.3%
-1.41M▼ 124.7%
33.5M▲ 0%
Free Cash Flow
-2.49M▲ 0%
-5.36M▼ 115.8%
-20.48M▼ 281.9%
-33.46M▼ 63.4%
-53.29M▼ 59.2%
-49.26M▲ 7.6%
-29.83M▲ 39.4%
-31.28M▲ 0%
FCF Margin %
--------
FCF Growth %
--115.77%-281.88%-63.36%-59.25%7.56%39.43%26.02%
FCF per Share
-0.13-0.29-1.09-2.18-2.26-1.65-0.99-0.92
FCF Conversion (FCF/Net Income)
0.07x0.39x0.95x0.82x0.82x0.96x0.85x0.91x
Interest Paid
00000000
Taxes Paid
00000000

ANTX Key Ratios

AN2 Therapeutics, Inc. (ANTX) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric202020212022202320242025TTM
Return on Equity (ROE)-359.68%-66.64%-52.08%-58.83%-49.69%-52.14%-52.35%
Return on Invested Capital (ROIC)--66.73%-53.72%-58.93%-48.26%-61.06%-72.14%
Debt / Equity--0.00x---0.00x
Interest Coverage---79.68x----
FCF Conversion0.39x0.95x0.82x0.82x0.96x0.85x0.91x
Related:ANTX Dividend History·ANTX Revenue History·ANTX Price History·ANTX P/E History·ANTX Financial Ratios·ANTX Institutional Holders

ANTX SEC Filings & Documents

AN2 Therapeutics, Inc. (ANTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 11, 2026·SEC

Material company update

Apr 9, 2026·SEC

Material company update

Mar 20, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 25, 2025·SEC

FY 2024

Mar 29, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 11, 2026·SEC

FY 2025

Nov 12, 2025·SEC

FY 2025

Aug 12, 2025·SEC

ANTX Frequently Asked Questions

AN2 Therapeutics, Inc. (ANTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

AN2 Therapeutics, Inc. (ANTX) grew revenue by 0.0% over the past year. Growth has been modest.

AN2 Therapeutics, Inc. (ANTX) reported a net loss of $34.6M for fiscal year 2025.

Dividend & Returns

AN2 Therapeutics, Inc. (ANTX) has a return on equity (ROE) of -52.1%. Negative ROE indicates the company is unprofitable.

AN2 Therapeutics, Inc. (ANTX) had negative free cash flow of $31.3M in fiscal year 2025, likely due to heavy capital investments.

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