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Ardelyx, Inc. (ARDX) 10-Year Financial Performance & Capital Metrics

ARDX •
HealthcareBiotechnologyCommercial Specialty Pharma
AboutArdelyx, Inc., a biopharmaceutical company, discovers, develops, and commercializes medicines to treat gastrointestinal and cardiorenal therapeutic areas in the United States and internationally. The company's lead product candidate is tenapanor, which has completed Phase III clinical trial for the treatment of patients with irritable bowel syndrome with constipation, as well as in Phase III clinical trial to control serum phosphorus in adult patients with chronic kidney disease (CKD)on dialysis, or hyperphosphatemia. It is also developing RDX013, a potassium secretagogue, for the treatment of elevated serum potassium, or hyperkalemia, a problem among certain patients with kidney and/or heart disease; and RDX020, an early-stage program in metabolic acidosis, a serious electrolyte disorder in patients with CKD. The company has agreements with Kyowa Kirin in Japan, Fosun Pharmaceutical Industrial Development Co. Ltd. in China, and Knight Therapeutics, Inc. in Canada for the development and commercialization of tenapanor in their respective territories. The company was formerly known as Nteryx, Inc. and changed its name to Ardelyx, Inc. in June 2008. Ardelyx, Inc. was incorporated in 2007 and is headquartered in Waltham, Massachusetts.Show more
  • Revenue $407M +22.1%
  • EBITDA -$41M -58.3%
  • Net Income -$62M -57.4%
  • EPS (Diluted) -0.26 -52.9%
  • Gross Margin 90.29% +6.4%
  • EBITDA Margin -10.06% -29.6%
  • Operating Margin -10.06% -20.1%
  • Net Margin -15.12% -28.9%
  • ROE -36.21% -57.3%
  • ROIC -10.81% -19.4%
  • Debt/Equity 1.25 +40.7%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 82 (top 18%)
  • ✓Strong 5Y sales CAGR of 121.9%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y32.72%
5Y121.9%
3Y98.4%
TTM58.12%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM22.09%

EPS CAGR

10Y-
5Y-
3Y-
TTM22.73%

ROCE

10Y Avg-48.82%
5Y Avg-45.14%
3Y Avg-17.97%
Latest-10.63%

Peer Comparison

Commercial Specialty Pharma
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Technical
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
ALKSAlkermes plc4.98B30.1021.05-5.25%16.37%13.28%0.01%0.04
ADMAADMA Biologics, Inc.3.71B15.5719.2265.15%42.87%48.57%2.97%0.24
UTHRUnited Therapeutics Corporation21.99B503.9018.0910.61%41.94%18.81%4.73%
PCSAProcessa Pharmaceuticals, Inc.114.71M2.17-0.56-221.71%0.04
UNCYUnicycive Therapeutics, Inc.144.49M6.93-1.24-100%-89.15%0.10
PTHSPelthos Therapeutics Inc.85.29M26.36-1.95-318.41%-40.48%
MISTMilestone Pharmaceuticals Inc.145.64M1.71-2.55-100%-282.97%4.17
AMRNAmarin Corporation plc5.74B13.80-3.45-25.51%-38.01%-18.78%0.02

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Profit & Loss

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Sales/Revenue+24.03M42M2.61M5.28M7.57M10.1M52.16M124.46M333.62M407.32M
Revenue Growth %0%74.81%-93.79%102.57%43.36%33.36%416.57%138.61%168.06%22.09%
Cost of Goods Sold+1.29M8.4M466K600K145K1M4.12M17.8M50.56M39.54M
COGS % of Revenue5.39%20%17.88%11.36%1.92%9.9%7.89%14.3%15.15%9.71%
Gross Profit+22.73M33.6M2.14M4.68M7.43M9.1M48.04M106.66M283.06M367.78M
Gross Margin %94.61%80%82.13%88.64%98.08%90.1%92.11%85.7%84.85%90.29%
Gross Profit Growth %-2.01%47.82%-93.63%118.64%58.64%22.5%428.1%122.02%165.38%29.93%
Operating Expenses+112.89M98.72M93.09M95.94M98.21M163.44M111.8M169.94M311.01M408.76M
OpEx % of Revenue469.89%235.04%3570.69%1816.78%1297.13%1618.73%214.35%136.54%93.22%100.35%
Selling, General & Admin18.73M23.23M23.71M24.27M33.15M72.3M76.6M134.4M258.69M337.23M
SG&A % of Revenue77.97%55.31%909.67%459.52%437.89%716.08%146.86%107.99%77.54%82.79%
Research & Development94.16M75.48M69.37M71.68M65.05M91.14M35.2M35.54M52.32M71.53M
R&D % of Revenue391.91%179.72%2661.03%1357.26%859.24%902.64%67.49%28.55%15.68%17.56%
Other Operating Expenses508K000000000
Operating Income+-112.89M-65.11M-90.95M-91.26M-90.78M-154.35M-63.76M-63.28M-27.95M-40.98M
Operating Margin %-469.89%-155.04%-3488.57%-1728.14%-1199.05%-1528.63%-122.24%-50.84%-8.38%-10.06%
Operating Income Growth %-284.14%42.32%-39.67%-0.35%0.53%-70.02%58.69%0.76%55.83%-46.61%
EBITDA+-111.6M-62.48M-88.27M-86.92M-86.81M-151.54M-62.62M-61.98M-25.89M-40.98M
EBITDA Margin %-464.5%-148.75%-3385.85%-1645.96%-1146.6%-1500.83%-120.05%-49.8%-7.76%-10.06%
EBITDA Growth %-290.76%44.02%-41.28%1.52%0.13%-74.57%58.68%1.01%58.24%-58.29%
D&A (Non-Cash Add-back)1.29M2.64M2.68M4.34M3.97M2.81M1.14M1.29M2.06M0
EBIT-112.89M-63.16M-87.76M-88.91M-89.21M-153.66M-62.13M-56.65M-18.78M0
Net Interest Income+00-3.53M-5.73M-5.1M-4.5M-5.07M-8.87M-20.09M0
Interest Income0000000000
Interest Expense003.53M5.73M5.1M4.5M5.07M8.87M20.09M-20.1M
Other Income/Expense508K1.96M-347K-3.37M-3.53M-3.81M-3.44M-2.24M-10.92M-19.65M
Pretax Income+-112.39M-63.16M-91.29M-94.64M-94.31M-158.16M-67.2M-65.52M-38.87M-60.63M
Pretax Margin %-467.77%-150.38%-3501.88%-1792.03%-1245.69%-1566.42%-128.84%-52.65%-11.65%-14.89%
Income Tax+29K1.18M4K303K2K4K8K547K266K969K
Effective Tax Rate %100%101.87%100%100.32%100%100%100.01%100.83%100.68%101.6%
Net Income+-112.39M-64.34M-91.3M-94.94M-94.31M-158.16M-67.21M-66.07M-39.14M-61.6M
Net Margin %-467.77%-153.19%-3502.03%-1797.77%-1245.71%-1566.46%-128.85%-53.08%-11.73%-15.12%
Net Income Growth %-279.42%42.75%-41.9%-3.99%0.66%-67.7%57.51%1.7%40.76%-57.4%
Net Income (Continuing)-112.39M-64.34M-91.3M-94.94M-94.31M-158.16M-67.21M-66.07M-39.14M-61.6M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-2.80-1.36-1.62-1.47-1.05-1.52-0.42-0.30-0.17-0.26
EPS Growth %-117.05%51.43%-19.12%9.26%28.57%-44.76%72.37%28.57%43.33%-52.94%
EPS (Basic)-2.80-1.36-1.62-1.47-1.05-1.52-0.42-0.30-0.17-0.26
Diluted Shares Outstanding40.12M47.44M56.22M64.48M89.58M104.21M158.69M219.33M235.23M241.03M
Basic Shares Outstanding40.12M47.44M56.22M64.48M89.58M104.21M158.69M219.33M235.23M241.03M
Dividend Payout Ratio----------

Balance Sheet

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Current Assets+203.99M149.87M177.72M252.38M195.24M133.65M153.6M246.11M356.45M382.32M
Cash & Short-Term Investments200.82M133.98M168.09M247.51M186.48M116.69M123.91M184.3M250.1M264.69M
Cash Only74.6M75.38M78.77M181.13M91.03M72.43M96.14M21.47M64.93M68M
Short-Term Investments126.22M58.59M89.32M66.38M95.45M44.26M27.77M162.83M185.17M196.69M
Accounts Receivable010.8M5.08M750K0502K7.73M22.03M57.7M71.85M
Days Sales Outstanding-93.82711.9451.84-18.1554.1264.6163.1364.38
Inventory0000003.28M12.45M21.17M17.73M
Days Inventory Outstanding------290.97255.33152.86163.73
Other Current Assets3.17M000015.11M8.41M11.1M28.05M
Total Non-Current Assets+9.14M8.03M5.61M7.41M6.32M16.26M36.46M51.47M79.3M119.29M
Property, Plant & Equipment8.99M8.03M5.61M7.41M4.21M15.11M10.52M6.6M3.88M6.98M
Fixed Asset Turnover2.67x5.23x0.46x0.71x1.80x0.67x4.96x18.86x86.09x58.36x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments00002.11M00000
Other Non-Current Assets148K00001.15M25.95M44.87M75.43M112.31M
Total Assets+213.13M157.9M183.33M259.78M201.56M149.91M190.07M297.58M435.75M501.6M
Asset Turnover0.11x0.27x0.01x0.02x0.04x0.07x0.27x0.42x0.77x0.81x
Asset Growth %82.25%-25.91%16.1%41.7%-22.41%-25.62%26.78%56.57%46.43%15.11%
Total Current Liabilities+19.2M17.87M17.73M22.22M28.42M52.82M65.6M50.39M77.83M88.61M
Accounts Payable5.63M3.93M1.15M2.19M5.63M4.28M10.86M11.14M16M19.23M
Days Payables Outstanding1.59K170.9899.181.33K14.16K1.56K962.72228.46115.52177.57
Short-Term Debt0003.79M6.28M32.26M26.71M001.48M
Deferred Revenue (Current)001M4.54M4.18M04.21M7.18M10.69M1.21M
Other Current Liabilities10.4M10.71M12.86M4.64M5.22M1.24M10.09M15.04M49.58M85.92M
Current Ratio10.62x8.39x10.02x11.36x6.87x2.53x2.34x4.88x4.58x4.31x
Quick Ratio10.62x8.39x10.02x11.36x6.87x2.53x2.29x4.64x4.31x4.11x
Cash Conversion Cycle-------617.6491.48100.4850.54
Total Non-Current Liabilities+779K720K49.79M50.91M47.03M14.47M26.13M80.37M184.63M246.05M
Long-Term Debt0049.21M48.83M46.62M0049.82M150.85M206.47M
Capital Lease Obligations0002.08M413K9.75M5.86M1.73M1.02M0
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities779K720K582K004.73M11.25M20.18M25.53M39.58M
Total Liabilities19.98M18.59M67.52M73.13M75.45M67.3M91.74M130.76M262.46M334.65M
Total Debt+0049.21M57.31M55.44M45.5M36.46M55.98M153.44M207.95M
Net Debt-74.6M-75.38M-29.56M-123.83M-35.6M-26.92M-59.68M34.51M88.51M139.96M
Debt / Equity--0.42x0.31x0.44x0.55x0.37x0.34x0.89x1.25x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage---25.73x-15.94x-17.80x-34.28x-12.57x-7.13x-1.39x-
Total Equity+193.15M139.31M115.81M186.66M126.11M82.62M98.33M166.82M173.29M166.95M
Equity Growth %77.36%-27.87%-16.87%61.17%-32.44%-34.49%19.02%69.65%3.88%-3.66%
Book Value per Share4.812.942.062.891.410.790.620.760.740.69
Total Shareholders' Equity193.15M139.31M115.81M186.66M126.11M82.62M98.33M166.82M173.29M166.95M
Common Stock5K5K6K9K9K13K20K23K24K24K
Retained Earnings-213.88M-278.21M-365.51M-460.45M-554.76M-712.93M-780.14M-846.2M-885.34M-946.94M
Treasury Stock0000000000
Accumulated OCI-71K-47K-38K20K-4K-6K-54K224K57K198K
Minority Interest0000000000

Cash Flow

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Cash from Operations+-92.53M-65.19M-70.27M-76.48M-81.44M-152.55M-70.04M-89.72M-44.81M-42.48M
Operating CF Margin %-385.14%-155.21%-2695.59%-1448.29%-1075.62%-1510.85%-134.29%-72.09%-13.43%-10.43%
Operating CF Growth %-28.81%29.55%-7.8%-8.84%-6.47%-87.33%54.08%-28.09%50.06%5.19%
Net Income-112.39M-64.34M-91.3M-94.94M-94.31M-158.16M-67.21M-66.07M-39.14M-61.6M
Depreciation & Amortization1.29M2.64M2.68M2.5M1.82M1.44M1.14M1.29M2.06M3.06M
Stock-Based Compensation5.32M9.59M9.23M9.94M10.58M12.04M10.75M13.53M37.38M48.96M
Deferred Taxes-86K11K-1.02M-262K315K-190K0000
Other Non-Cash Items540K567K792K3.3M3.37M4.25M4.84M4.91M4.05M-32.91M
Working Capital Changes12.79M-13.66M9.35M2.98M-3.21M-11.92M-19.57M-43.39M-49.17M0
Change in Receivables0-10.8M10.71M85K750K-502K-7.23M-14.3M-35.67M-14.14M
Change in Inventory0-1.9M1.88M-3.41M-750K-10.37M-28.35M-21.14M-41.7M-31.92M
Change in Payables2.15M-1.03M-2.73M39K3.44M-1.35M6.58M279K4.86M3.23M
Cash from Investing+-131.08M65.29M-29.89M23.37M-31.44M50.95M18.41M-131.25M-18.32M-8.96M
Capital Expenditures-4.87M-2.35M-311K-325K-324K-1.87M-55K-344K-1.01M-1.49M
CapEx % of Revenue20.25%5.61%11.93%6.15%4.28%18.49%0.11%0.28%0.3%0.37%
Acquisitions000-23.7M31.44M-52.81M0000
Investments----------
Other Investing-126.21M67.64M-29.58M23.7M-31.44M52.81M1.8M000
Cash from Financing+191.2M685K103.55M155.48M22.78M83M75.34M146.29M106.59M54.51M
Debt Issued (Net)0049.29M0-125K-19.44M-6.07M22.39M99.45M0
Equity Issued (Net)1000K01000K1000K1000K1000K1000K1000K1000K0
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing631K685K491K574K1.85M1.3M9.78M4.67M-1M54.51M
Net Change in Cash-32.41M785K3.38M102.36M-90.1M-18.6M23.71M-74.67M43.46M3.07M
Free Cash Flow+-97.4M-67.55M-70.58M-76.81M-81.76M-154.42M-70.1M-90.06M-45.82M-43.98M
FCF Margin %-405.39%-160.82%-2707.52%-1454.44%-1079.9%-1529.35%-134.4%-72.36%-13.73%-10.8%
FCF Growth %-29.36%30.65%-4.5%-8.82%-6.44%-88.87%54.6%-28.48%49.12%4.03%
FCF per Share-2.43-1.42-1.26-1.19-0.91-1.48-0.44-0.41-0.19-0.18
FCF Conversion (FCF/Net Income)0.82x1.01x0.77x0.81x0.86x0.96x1.04x1.36x1.14x0.69x
Interest Paid0004.92M4.2M3.47M2.9M4.24M11.41M0
Taxes Paid03K4K2K1K4K6K51K266K0

Key Ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-74.42%-38.7%-71.57%-62.78%-60.31%-151.55%-74.28%-49.83%-23.01%-36.21%
Return on Invested Capital (ROIC)-140.59%-53.52%-90.84%-91.83%-88.8%-158.35%-101.37%-39.55%-9.05%-10.81%
Gross Margin94.61%80%82.13%88.64%98.08%90.1%92.11%85.7%84.85%90.29%
Net Margin-467.77%-153.19%-3502.03%-1797.77%-1245.71%-1566.46%-128.85%-53.08%-11.73%-15.12%
Debt / Equity--0.42x0.31x0.44x0.55x0.37x0.34x0.89x1.25x
Interest Coverage---25.73x-15.94x-17.80x-34.28x-12.57x-7.13x-1.39x-
FCF Conversion0.82x1.01x0.77x0.81x0.86x0.96x1.04x1.36x1.14x0.69x
Revenue Growth0%74.81%-93.79%102.57%43.36%33.36%416.57%138.61%168.06%22.09%

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