15 years of historical data (2011–2025) · Healthcare · Biotechnology
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
argenx SE trades at 44.7x earnings, roughly in line with its 5-year average of 45.5x, sitting at the 50th percentile of its historical range. Compared to the Healthcare sector median P/E of 22.1x, the stock trades at a premium of 102%. On a free-cash-flow basis, the stock trades at 64.3x P/FCF, roughly in line with the 5-year average of 65.8x.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $54.3B | $55.5B | $40.1B | $21.7B | $20.6B | $17.9B | $13.4B | $6.2B | $3.5B | $1.6B | — |
| Enterprise Value | $50.9B | $52.1B | $38.6B | $19.7B | $19.8B | $16.6B | $12.2B | $5.8B | $3.1B | $1.3B | — |
| P/E Ratio → | 44.71 | 42.84 | 48.12 | — | — | — | — | — | — | — | — |
| P/S Ratio | 13.08 | 13.37 | 18.30 | 17.74 | 50.16 | 35.97 | 323.80 | 79.01 | 140.65 | 35.57 | — |
| P/B Ratio | 7.91 | 7.58 | 7.29 | 5.31 | 7.32 | 7.06 | 7.98 | 5.25 | 5.61 | 3.76 | — |
| P/FCF | 64.33 | 65.77 | — | — | — | — | — | 59.10 | — | — | — |
| P/OCF | 63.87 | 65.29 | — | — | — | — | — | 40.88 | — | — | — |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
argenx SE's enterprise value stands at 47.0x EBITDA, roughly in line with its 5-year average of 48.1x. The Healthcare sector median is 14.2x, placing the stock at a 231% premium on an enterprise-value basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 12.55 | 17.63 | 16.08 | 48.24 | 33.31 | 294.60 | 74.36 | 127.56 | 30.33 | — |
| EV / EBITDA | 47.02 | 48.14 | — | — | — | — | — | — | — | — | — |
| EV / EBIT | 48.27 | 40.63 | 440.69 | — | — | — | — | — | — | — | — |
| EV / FCF | — | 61.73 | — | — | — | — | — | 55.62 | — | — | — |
Margins and return-on-capital ratios measuring operating efficiency
argenx SE earns an operating margin of 25.4%. Operating margins have expanded from -34.7% to 25.4% over the past 3 years, signaling improving operational efficiency. ROE of 20.2% indicates solid capital efficiency. ROIC of 19.9% represents solid returns on invested capital.
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 89.1% | 89.1% | 89.6% | 90.4% | 92.8% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| Operating Margin | 25.4% | 25.4% | -1.0% | -34.7% | -175.4% | -70.1% | -1158.1% | -253.5% | -381.0% | -63.0% | -145.6% |
| Net Profit Margin | 31.1% | 31.1% | 38.0% | -24.1% | -172.8% | -82.0% | -1475.3% | -230.9% | -310.2% | -77.1% | -145.3% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 20.2% | 20.2% | 17.4% | -8.5% | -26.5% | -19.4% | -42.6% | -20.2% | -14.8% | -14.0% | -41.9% |
| ROA | 17.4% | 17.4% | 15.5% | -7.7% | -23.7% | -15.9% | -31.3% | -16.0% | -13.8% | -12.1% | -27.8% |
| ROIC | 19.9% | 19.9% | -0.5% | -15.6% | -33.4% | -31.2% | -55.9% | -26.9% | -29.3% | -26.3% | — |
| ROCE | 16.4% | 16.4% | -0.4% | -12.2% | -26.8% | -15.5% | -28.2% | -19.4% | -18.2% | -11.2% | -38.2% |
Solvency and debt-coverage ratios — lower is generally safer
argenx SE carries a Debt/EBITDA ratio of 0.1x, which is very conservative (98% below the sector average of 3.2x). The company holds a net cash position — cash of $3.5B exceeds total debt of $83M, providing substantial financial flexibility for buybacks, acquisitions, or weathering downturns. Interest coverage of 314.2x signals virtually no risk of debt distress — earnings comfortably cover interest obligations.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.01 | 0.01 | 0.01 | 0.00 | 0.00 | 0.00 | 0.01 | 0.01 | — | — | — |
| Debt / EBITDA | 0.08 | 0.08 | — | — | — | — | — | — | — | — | — |
| Net Debt / Equity | — | -0.47 | -0.27 | -0.50 | -0.28 | -0.52 | -0.72 | -0.31 | -0.52 | -0.55 | -1.42 |
| Net Debt / EBITDA | -3.15 | -3.15 | — | — | — | — | — | — | — | — | — |
| Debt / FCF | — | -4.04 | — | — | — | — | — | -3.48 | — | — | -9.23 |
| Interest Coverage | 314.23 | 314.23 | 39.50 | -335.83 | -331.56 | -363.73 | -1498.68 | -1264.60 | — | — | — |
Net cash position: cash ($3.5B) exceeds total debt ($83M)
Short-term solvency ratios and asset-utilisation metrics
argenx SE's current ratio of 5.23x is well above the 1.0 safety threshold, indicating strong short-term liquidity with ample room to cover current liabilities. The quick ratio of 4.87x is notably lower than the current ratio, indicating a significant portion of current assets is tied up in inventory. The current ratio has declined from 9.75x to 5.23x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 5.23 | 5.23 | 7.29 | 9.75 | 9.18 | 8.44 | 6.26 | 8.58 | 14.29 | 14.96 | 3.15 |
| Quick Ratio | 4.87 | 4.87 | 6.68 | 9.01 | 8.42 | 8.08 | 6.19 | 8.58 | 14.29 | 14.96 | 3.15 |
| Cash Ratio | 3.36 | 3.36 | 5.04 | 7.52 | 7.25 | 7.76 | 6.08 | 8.35 | 14.09 | 14.67 | 2.99 |
| Asset Turnover | — | 0.48 | 0.35 | 0.27 | 0.13 | 0.17 | 0.02 | 0.05 | 0.04 | 0.10 | 0.14 |
| Inventory Turnover | 0.95 | 0.95 | 0.56 | 0.38 | 0.13 | — | — | — | — | — | — |
| Days Sales Outstanding | — | 145.62 | 151.50 | 148.60 | 246.39 | 28.05 | 65.85 | 168.26 | 64.71 | 7.06 | 26.37 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
argenx SE does not currently pay a dividend and has no material buyback yield, reinvesting earnings back into the business. The earnings yield of 2.2% (inverse of P/E) provides a useful comparison to bond yields when assessing the stock's relative attractiveness to fixed income.
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | — | — | — | — | — | — | — | — | — | — | — |
| Payout Ratio | — | — | — | — | — | — | — | — | — | — | — |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | 2.2% | 2.3% | 2.1% | — | — | — | — | — | — | — | — |
| FCF Yield | 1.6% | 1.5% | — | — | — | — | — | 1.7% | — | — | — |
| Buyback Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — |
| Total Shareholder Yield | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | — |
| Shares Outstanding | — | $66M | $65M | $57M | $54M | $51M | $45M | $39M | $36M | $25M | $19M |
Compare ARGX with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
| $54B | 44.7 | 47.0 | 64.3 | 89.1% | 25.4% | 20.2% | 19.9% | 0.1 | |
| $3B | -4.7 | — | — | 83.8% | -79.5% | -607.5% | -89.4% | — | |
| $37B | 119.4 | 65.9 | 79.7 | 81.8% | 13.5% | 73.3% | 33.4% | 2.3 | |
| $2B | -2.5 | — | — | 59.9% | -29.9% | -53.5% | -31.4% | — | |
| $11B | 30.4 | 16.1 | 14.5 | 77.1% | 16.6% | 5.9% | 7.4% | 1.0 | |
| $12B | -31.1 | — | — | 98.3% | -40.5% | -70.7% | -12.8% | — | |
| $4B | 9.4 | 25.7 | 35.2 | 91.7% | 9.8% | 39.9% | 10.0% | 0.4 | |
| $7B | -12.8 | — | — | — | — | -64.8% | — | — | |
| $1B | -23.3 | — | — | 89.5% | -10.1% | -36.2% | -10.7% | — | |
| $115B | 29.5 | 22.9 | 36.0 | 85.0% | 39.4% | 22.5% | 23.0% | 0.8 | |
| $8B | 26.8 | 11.2 | 12.6 | 78.1% | 58.4% | 153.6% | 32.1% | 2.4 | |
| Healthcare Median | — | 22.1 | 14.2 | 18.5 | 63.9% | -4.3% | -32.6% | -11.6% | 3.2 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Includes 30+ ratios · 15 years · Updated daily
Deep dive into ARGX consensus models and risk factors.
DCF models, multiple analysis, and analyst estimates.
10-year return with dividends reinvested.
See how regular investing compounds over time.
Compare growth, multiples, and margins vs sector.
Quick answers to the most common questions about buying ARGX stock.
argenx SE's current P/E ratio is 44.7x. The historical average is 45.5x. This places it at the 50th percentile of its historical range.
argenx SE's current EV/EBITDA is 47.0x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 48.1x.
argenx SE's return on equity (ROE) is 20.2%. This is above the typical threshold of 15-20% considered good for most companies. The historical average is -21.4%.
Based on historical data, argenx SE is trading at a P/E of 44.7x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
argenx SE has 89.1% gross margin and 25.4% operating margin. Operating margin above 20% indicates strong pricing power and cost efficiency.
argenx SE's Debt/EBITDA ratio is 0.1x, indicating low leverage. A ratio below 2x is generally considered financially healthy.