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argenx SE (ARGX) 10-Year Financial Performance & Capital Metrics

ARGX •
HealthcareBiotechnologyImmunology and Inflammation Therapies
Aboutargenx SE, a biotechnology company, engages in the developing of various therapies for the treatment of autoimmune diseases in the United States, Japan, Europe, Middle East, Africa, and China. Its lead product candidate is efgartigimod for the treatment of patients with myasthenia gravis, immune thrombocytopenia, pemphigus vulgaris, generalized myasthenia gravis, chronic inflammatory demyelinating polyneuropathy, thyroid eye disease, bullous pemphigoid, myositis, primary sjögren's syndrome, post-covid postural orthostatic tachycardia syndrome, membranous nephropathy, lupus nephropathy, anca-associated vasculitis, and antibody mediated rejection; ENHANZE SC; Empasiprubart for multifocal motor neuropath, delayed graft function, and dermatomyositis; and ARGX-119 for congenital myasthenic syndrome and amyotrophic lateral sclerosis. The company is developing ARGX-213 targets FcRn; ARGX-121 and ARGX-220 targets immune system; ARGX-109 targets IL-6; ARGX-118 for inflammation; and ARGX-109, as well as cusatuzumab, ARGX-112, ARGX-114, and ARGX-115. It owns VYVGART; VYVGART HYTRULO; VYVDURA; ARGENX; ABDEG; NHANCE; SIMPLE ANTIBODY; and ARGENXMEDHUB. The company has strategic partnership with AbbVie S.À.R.L., Zai Lab Limited, and LEO Pharma A/S; and collaboration and license agreement with Genor Biopharma Co. Ltd, Université Catholique de Louvain, Sopartec S.A., NYU Langone Health, Leiden University Medical Center, AgomAb Therapeutics NV, Broteio Pharma B.V., VIB vzw, University of Texas, BioWa, Inc., and Shire International GmbH. It has collaboration agreement with Genmab A/S to discover, develop, and commercialize novel therapeutic antibodies with applications in immunology and oncology, as well as a strategic collaboration with IQVIA Holdings Inc. to provide safety systems and services. argenx SE was incorporated in 2008 and is based in Amsterdam, the Netherlands.Show more
  • Revenue $2.19B +78.6%
  • EBITDA -$4M +98.7%
  • Net Income $833M +382.3%
  • EPS (Diluted) 12.78 +347.7%
  • Gross Margin 89.62% -0.9%
  • EBITDA Margin -0.19% +99.3%
  • Operating Margin -0.99% +97.1%
  • Net Margin 38.03% +258.1%
  • ROE 17.36% +303.3%
  • ROIC -0.53% +96.6%
  • Debt/Equity 0.01 +45.5%
  • Interest Coverage -9.76 +97.9%
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Strong 5Y sales CAGR of 94.6%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Shares diluted 14.0% in last year

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y85.39%
5Y94.61%
3Y63.92%
TTM335.2%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM176.97%

EPS CAGR

10Y-
5Y-
3Y-
TTM167.07%

ROCE

10Y Avg-20.84%
5Y Avg-16.64%
3Y Avg-13.15%
Latest-0.45%

Peer Comparison

Immunology and Inflammation Therapies
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Size & Scale
Valuation
Per Share
Growth
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Quality & Returns
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Total Return (DRIP)
Technical
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Shares & Dilution
Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
TGTXTG Therapeutics, Inc.4.75B30.09200.6040.8%13.31%21.87%1.14
APLSApellis Pharmaceuticals, Inc.2.65B20.96116.44-11.77%3.25%7.48%1.71%0.30
ARGXargenx SE47.46B766.9260.0178.6%23.34%15.14%0.01
KNSAKiniksa Pharmaceuticals, Ltd.3.39B44.4959.3260.09%17.52%20.92%0.75%0.02
AUPHAurinia Pharmaceuticals Inc.1.88B14.176.8520.38%101.47%49.4%7.22%0.13
GLPGGalapagos N.V.2.22B33.665.88303.48%28.85%9.92%0.00
AKTXAkari Therapeutics, Plc12.56B0.24-0.00-69.35%0.15
RAPTRAPT Therapeutics, Inc.7.65B57.98-2.27-69.51%0.02

Compare ARGX vs Peers

Analyze head-to-head performance against top industry competitors across valuation, growth, and profitability metrics.

vs CANF

Compare head-to-head with Can-Fite BioPharma Ltd.

vs AKTX

Compare head-to-head with Akari Therapeutics, Plc

Compare Top 5

vs CANF, AKTX, ABVX, RAPT

Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+7.49M15.47M43.69M24.57M78.46M41.24M497.28M410.75M1.23B2.19B
Revenue Growth %64.07%106.51%182.33%-43.75%219.3%-47.44%1105.72%-17.4%198.56%78.6%
Cost of Goods Sold+000000029.43M117.83M227.29M
COGS % of Revenue-------7.17%9.61%10.38%
Gross Profit+7.49M15.47M43.69M24.57M78.46M41.24M497.28M381.31M1.11B1.96B
Gross Margin %100%100%100%100%100%100%100%92.83%90.39%89.62%
Gross Profit Growth %64.07%106.51%182.33%-43.75%219.3%-47.44%1105.72%-23.32%190.7%77.08%
Operating Expenses+24.55M38M71.2M118.2M277.35M518.86M846.02M1.1B1.53B1.98B
OpEx % of Revenue327.69%245.55%162.98%481.02%353.49%1258.06%170.13%268.21%125.05%90.61%
Selling, General & Admin5.38M7.37M14.93M31.42M72.15M170.55M305.52M469.92M709.54M1.06B
SG&A % of Revenue71.87%47.65%34.18%127.88%91.95%413.53%61.44%114.41%57.86%48.18%
Research & Development22.56M33.19M62.07M95.64M220.77M370.49M580.52M663.37M859.49M983.42M
R&D % of Revenue301.08%214.48%142.09%389.21%281.37%898.31%116.74%161.5%70.09%44.9%
Other Operating Expenses-3.39M-2.56M-5.81M-8.86M-15.56M-22.18M-40.02M-31.63M-35.5M-54.16M
Operating Income+-17.06M-22.52M-27.51M-93.63M-198.89M-477.62M-348.75M-720.34M-425.05M-21.65M
Operating Margin %-227.69%-145.55%-62.98%-381.02%-253.49%-1158.06%-70.13%-175.37%-34.66%-0.99%
Operating Income Growth %-30.6%-32.01%-22.15%-240.31%-112.43%-140.14%26.98%-106.55%40.99%94.91%
EBITDA+-16.85M-22.17M-26.99M-93.06M-196.47M-473.7M-342.88M-616M-313.57M-4.13M
EBITDA Margin %-224.83%-143.28%-61.78%-378.72%-250.4%-1148.56%-68.95%-149.97%-25.57%-0.19%
EBITDA Growth %-30.56%-31.61%-21.73%-244.8%-111.11%-141.11%27.62%-79.65%49.1%98.68%
D&A (Non-Cash Add-back)214.29K351.27K521.87K563.94K2.42M3.92M5.87M104.34M111.48M17.53M
EBIT-16.74M-22.52M-32.97M-93.63M-175.78M-604.95M-398.65M-727.12M-303.59M87.64M
Net Interest Income+83.09K64.15K197.95K4.23M8.67M4.75M2.39M22.55M92.06M136.28M
Interest Income83.09K64.15K197.95K4.23M8.8M5.15M3.48M24.74M92.96M138.5M
Interest Expense0000139K403.66K1.1M2.19M904K2.22M
Other Income/Expense320.34K44.17K-5.46M18.3M22.97M-127.73M-51M-8.97M120.55M106.83M
Pretax Income+-16.74M-22.48M-32.97M-75.32M-175.92M-605.35M-399.74M-729.31M-304.5M85.18M
Pretax Margin %-223.42%-145.27%-75.46%-306.53%-224.21%-1467.77%-80.39%-177.56%-24.83%3.89%
Income Tax+00716.22K908.26K5.29M3.1M8.52M-19.72M-9.44M-747.86M
Effective Tax Rate %100%100%102.17%101.21%103.01%100.51%101.97%97.3%96.9%977.98%
Net Income+-16.74M-22.48M-33.68M-76.23M-181.21M-608.46M-407.63M-709.59M-295.05M833.04M
Net Margin %-223.42%-145.27%-77.1%-310.22%-230.95%-1475.29%-81.97%-172.76%-24.06%38.03%
Net Income Growth %-33.48%-34.28%-49.84%-126.32%-137.71%-235.78%33.01%-74.08%58.42%382.34%
Net Income (Continuing)-16.74M-22.48M-33.68M-76.23M-181.21M-608.46M-408.26M-709.59M-295.05M833.04M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-1.06-1.20-1.37-2.12-4.69-13.40-7.99-13.05-5.1612.78
EPS Growth %-32.5%-13.21%-14.17%-54.74%-121.23%-185.71%40.37%-63.33%60.46%347.67%
EPS (Basic)-1.06-1.19-1.37-2.12-4.69-13.40-7.99-13.05-5.1613.92
Diluted Shares Outstanding15.73M18.82M24.61M35.98M38.62M45.41M51.08M54.38M57.17M65.18M
Basic Shares Outstanding15.73M18.82M24.61M35.98M38.62M45.41M51.08M54.38M57.17M59.86M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+48.26M107.06M440.06M654.82M1.54B2.06B2.54B2.77B4.12B4.88B
Cash & Short-Term Investments46.28M101.73M431.62M645.81M1.5B2B2.34B2.19B3.18B3.38B
Cash Only38.83M94.55M228.98M321.48M372.16M1.22B1.33B800.74M2.05B1.5B
Short-Term Investments7.45M7.18M202.64M324.33M1.13B779.65M1B1.39B1.13B1.88B
Accounts Receivable719K1.12M845K4.36M36.17M7.44M38.22M277.27M499.27M909.1M
Days Sales Outstanding35.0226.377.0664.71168.2665.8528.05246.39148.6151.5
Inventory0000025.2M109.08M228.35M310.55M407.23M
Days Inventory Outstanding-------2.83K961.94653.97
Other Current Assets637K826.64K3.85M2.31M000000
Total Non-Current Assets+2M4.18M4.92M6.88M67.54M222.41M307.3M360.06M418.72M1.32B
Property, Plant & Equipment272.23K805.6K811K942.58K9.18M11.58M15.84M16.23M22.68M43.52M
Fixed Asset Turnover27.52x19.21x53.87x26.07x8.55x3.56x31.39x25.30x54.08x50.33x
Goodwill0000000000
Intangible Assets7.65K17.88K15.6K64.06K45.12M167.34M171.68M174.9M125.23M181.44M
Long-Term Investments1.09K1.05K1.2K1.14K2.92M6.31M53.17M40.48M47.16M49.7M
Other Non-Current Assets1.71M3.36M4.1M5.87M10.33M22.14M34.42M49.23M126.45M120.46M
Total Assets+50.25M111.24M444.98M661.7M1.61B2.28B2.85B3.13B4.54B6.2B
Asset Turnover0.15x0.14x0.10x0.04x0.05x0.02x0.17x0.13x0.27x0.35x
Asset Growth %-14.12%121.38%300.01%48.7%143.35%41.56%25.04%9.96%44.93%36.55%
Total Current Liabilities+9.43M34M29.41M45.82M179.7M328.49M301.24M302.28M422.99M669.92M
Accounts Payable2.94M4.63M5.28M6.87M10.51M206.32M208.85M188.72M245.56M342.23M
Days Payables Outstanding-------2.34K760.63549.58
Short-Term Debt00002.22M3.48M3.51M3.42M4.65M6.53M
Deferred Revenue (Current)4.5M37.27M16.95M23.21M136.28M46.33M0000
Other Current Liabilities449.73K329.08K0000828K22.62M73.35M156.95M
Current Ratio5.12x3.15x14.96x14.29x8.58x6.26x8.44x9.18x9.75x7.29x
Quick Ratio5.12x3.15x14.96x14.29x8.58x6.19x8.08x8.42x9.01x6.68x
Cash Conversion Cycle-------737.91349.92255.89
Total Non-Current Liabilities+010.59M1.75M8.01K250.11M276.86M14.81M18.29M21.96M34.32M
Long-Term Debt0000000000
Capital Lease Obligations00005.1M6.18M7.96M9.01M15.35M32.52M
Deferred Tax Liabilities000001.49M6.44M8.41M5.16M0
Other Non-Current Liabilities010.59M1.75M8.01K72K156K417K870K1.45M1.8M
Total Liabilities9.43M44.59M31.16M45.83M429.81M605.36M316.05M320.56M444.95M704.24M
Total Debt+00007.32M9.66M11.46M12.43M20M39.05M
Net Debt-38.83M-94.55M-228.98M-321.48M-364.84M-1.2B-1.32B-788.31M-2.03B-1.46B
Debt / Equity----0.01x0.01x0.00x0.00x0.00x0.01x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-----1430.88x-1183.22x-318.20x-328.47x-470.19x-9.76x
Total Equity+40.76M66.65M413.81M615.87M1.18B1.67B2.53B2.81B4.1B5.5B
Equity Growth %-33.08%63.54%520.87%48.83%91.66%41.82%51.38%11.03%45.63%34.19%
Book Value per Share2.593.5416.8117.1230.5736.8749.6251.7471.6784.36
Total Shareholders' Equity40.76M66.65M413.81M615.87M1.18B1.67B2.53B2.81B4.1B5.5B
Common Stock1.73M2.12M3.86M4.12M5.21M5.74M6.23M6.64M6.39M6.98M
Retained Earnings-55.89M-76.24M-120.65M-194.01M-383.48M-991.93M-1.4B-2.11B-2.4B-1.57B
Treasury Stock0000000000
Accumulated OCI5.08M7.88M14.11M35.4M53.04M321.21M465.41M71.72M72.07M66.71M
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-15.19M11.15M-43.84M-61.59M151.63M-398.46M-606.81M-862.81M-420.33M-82.75M
Operating CF Margin %-202.78%72.04%-100.36%-250.63%193.25%-966.13%-122.03%-210.06%-34.28%-3.78%
Operating CF Growth %-138.67%173.36%-493.33%-40.47%346.2%-362.79%-52.29%-42.19%51.28%80.31%
Net Income-17.06M-22.52M-27.51M-93.63M-198.89M-477.62M-348.75M-720.34M-425.05M833.04M
Depreciation & Amortization214.29K351.27K521.87K563.94K2.42M3.92M4.96M104.34M111.31M17.53M
Stock-Based Compensation2.48M3M5.12M21.94M44.24M96.93M179.37M157.03M232.97M235.18M
Deferred Taxes0000000000
Other Non-Cash Items-28773242.13K-666.94K-6.17M6.68M-101.44M-27.91M-30.67M-843.89M
Working Capital Changes-829K30.32M-22.02M10.2M310.03M-28.38M-340.95M-375.93M-308.89M-324.6M
Change in Receivables-712K-646K-146K-50.33K-25.71M21.96M-31.63M-222.26M-185.69M-422.36M
Change in Inventory00000-23.85M-83.88M-119.28M-83.03M-95.83M
Change in Payables000000000245.9M
Cash from Investing+18.38M-848K-194.41M-123.02M-833.27M344.69M-347.07M-461.18M308.21M-717.59M
Capital Expenditures-300K-883K-414K-712K-1.8M-1.07M-3.62M-837K-812K-1.8M
CapEx % of Revenue4%5.71%0.95%2.9%2.29%2.59%0.73%0.2%0.07%0.08%
Acquisitions0000000-2M-13M-7M
Investments----------
Other Investing18.68M35K-194M-122.31M-831.47M345.76M-115.21M-89.84M49.75M45.15M
Cash from Financing+260.2K46.93M366.35M279.88M733.73M833M1.12B843.76M1.34B279.76M
Debt Issued (Net)0000-1.51M-2.55M-3.85M-4.17M-3.8M-7.64M
Equity Issued (Net)260.2K1000K1000K1000K1000K1000K1000K1000K1000K1000K
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing0-1.43M-26.8M-12.64M-20.4M22.37M32.12M86.97M143.8M-21.32M
Net Change in Cash3.65M57.2M121.13M103.15M50.37M844.64M117.87M-533.94M1.25B-548.91M
Free Cash Flow+-15.5M10.24M-44.27M-62.37M104.89M-403.6M-728.25M-966.63M-464.14M-151.05M
FCF Margin %-206.85%66.18%-101.32%-253.81%133.69%-978.6%-146.45%-235.33%-37.85%-6.9%
FCF Growth %-135.15%166.08%-532.23%-40.9%268.18%-484.77%-80.44%-32.73%51.98%67.46%
FCF per Share-0.990.54-1.80-1.732.72-8.89-14.26-17.78-8.12-2.32
FCF Conversion (FCF/Net Income)0.91x-0.50x1.30x0.81x-0.84x0.65x1.49x1.22x1.42x-0.10x
Interest Paid000000000378.4K
Taxes Paid0000000000

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-32.94%-41.86%-14.02%-14.81%-20.18%-42.63%-19.37%-26.54%-8.54%17.36%
Return on Invested Capital (ROIC)-83.5%--26.3%-29.31%-26.88%-55.86%-31.18%-33.39%-15.57%-0.53%
Gross Margin100%100%100%100%100%100%100%92.83%90.39%89.62%
Net Margin-223.42%-145.27%-77.1%-310.22%-230.95%-1475.29%-81.97%-172.76%-24.06%38.03%
Debt / Equity----0.01x0.01x0.00x0.00x0.00x0.01x
Interest Coverage-----1430.88x-1183.22x-318.20x-328.47x-470.19x-9.76x
FCF Conversion0.91x-0.50x1.30x0.81x-0.84x0.65x1.49x1.22x1.42x-0.10x
Revenue Growth64.07%106.51%182.33%-43.75%219.3%-47.44%1105.72%-17.4%198.56%78.6%

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