Wall Street analyst price targets, ratings consensus & upside potential · Updated Feb 28, 2026
Last 12 months price action with 12-month analyst target path
As of February 28, 2026, AstraZeneca PLC (AZN) has a Wall Street consensus price target of $105.50, based on estimates from 41 covering analysts. With the stock currently trading at $208.45, this represents a potential downside of -49.4%. The company has a market capitalization of $323.16B.
Analyst price targets range from a low of $103.00 to a high of $108.00, representing a 5% spread in expectations. The median target of $105.50 aligns closely with the consensus average. The tight target dispersion indicates high conviction among analysts.
The current analyst consensus rating is Buy, with 20 analysts rating the stock as a Buy or Strong Buy,15 rating it Hold, and 6 rating it Sell or Strong Sell. The mixed ratings reflect uncertainty about near-term direction.
From a valuation perspective, AZN trades at a trailing P/E of 63.7x and forward P/E of 20.3x. The forward PEG ratio of 0.93 suggests the stock may be undervalued relative to its growth. Analysts expect EPS to grow +213.8% over the next year.
Our proprietary valuation model, which blends historical multiples with forward estimates, suggests a base-case price target of $361.15, with bear and bull scenarios of $33.54 and $271.75 respectively. Model confidence stands at 47/100, suggesting limited visibility into future performance.
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Start ComparisonAZN's consensus price target is $105.5, -49.4% below the current price of $208.45. The 41 analysts tracking AZN see downside risk at present valuations.
AZN has a consensus rating of "Buy" based on 41 Wall Street analysts. The rating breakdown is mixed, with 15 Hold ratings making up the largest segment. The consensus 12-month price target of $105.5 implies -49.4% downside from current levels.
AZN trades at a forward P/E of 20.2972x, representing a moderate valuation. With analysts targeting $105.5 (-49.4% implied move), the stock appears close to fair value.
The most bullish Wall Street analyst has a price target of $108 for AZN, while the most conservative target is $103. The consensus of $105.5 represents the median expectation. Our quantitative valuation model projects a bull case target of $272 based on optimistic growth and margin assumptions. These targets typically reflect 12-month expectations.
AZN is heavily covered by Wall Street, with 41 analysts providing price targets and ratings. Of these, 1 have Strong Buy ratings, 19 have Buy ratings, 15 recommend Hold, and 6 have Sell or Strong Sell ratings. Higher analyst coverage generally indicates greater institutional interest and more reliable consensus estimates.
The 12-month AZN stock forecast based on 41 Wall Street analysts shows a consensus price target of $105.5, with estimates ranging from $103 (bear case) to $108 (bull case). The median consensus rating is "Buy". Our proprietary valuation model produces a base case fair value of $361, with bear/bull scenarios of $34/$272.
Our quantitative valuation model calculates AZN's fair value at $361 (base case), with a bear case of $34 and bull case of $272. The model uses discounted cash flow analysis, historical growth rates, and margin mean-reversion to project FY+2 earnings, then applies an appropriate P/E multiple. The model confidence score is 47/100.
AZN trades at a forward P/E ratio of 20.3x based on next-twelve-months earnings estimates compared to a trailing P/E of 63.7x. The lower forward P/E indicates analysts expect earnings growth. A forward P/E is useful for comparing valuations when earnings are expected to change significantly.
Analysts are cautious on AZN, with 6 Sell ratings and a price target of $105.5 (-49.4% from current price). The "Buy" consensus suggests careful evaluation before buying. This information is for educational purposes only. Always conduct your own research, consider your financial situation, and consult a financial advisor before making investment decisions.
AZN analyst price targets range from $103 to $108, a 5% tight range reflecting strong analyst consensus. Differences stem from varying assumptions about revenue growth, profit margins, competitive dynamics, and valuation multiples. The $105.5 consensus represents the middle ground. Our model's $34-$272 range provides an independent fundamental perspective.