30 years of historical data (1996–2025) · Healthcare · Drug Manufacturers - General
Percentile shows where the current value sits in 30-year historical distribution. Sparklines show 5-year trend.
Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow
AstraZeneca PLC trades at 26.7x earnings, 92% below its 5-year average of 326.5x, sitting at the 59th percentile of its historical range. Compared to the Healthcare sector median P/E of 22.1x, the stock trades at a premium of 21%. On a free-cash-flow basis, the stock trades at 23.1x P/FCF, 26% below the 5-year average of 31.3x.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Market Cap | $271.2B | $274.1B | $203.2B | $210.0B | $212.5B | $165.3B | $132.6B | $131.4B | $93.0B | $81.8B | $68.2B |
| Enterprise Value | $295.2B | $298.1B | $227.8B | $232.8B | $235.5B | $189.7B | $145.2B | $144.3B | $107.3B | $96.3B | $80.0B |
| P/E Ratio → | 26.75 | 26.83 | 57.78 | 35.29 | 64.56 | 1448.13 | 41.39 | 98.06 | 43.18 | 27.24 | 19.52 |
| P/S Ratio | 4.62 | 4.67 | 3.76 | 4.58 | 4.79 | 4.42 | 4.98 | 5.39 | 4.21 | 3.64 | 2.96 |
| P/B Ratio | 5.61 | 5.63 | 4.97 | 5.36 | 5.73 | 4.21 | 8.48 | 9.00 | 6.62 | 4.92 | 4.09 |
| P/FCF | 23.05 | 23.30 | 27.93 | 31.98 | 29.36 | 43.93 | 60.47 | 258.16 | 74.58 | 41.78 | 37.25 |
| P/OCF | 18.61 | 18.81 | 17.13 | 20.30 | 21.67 | 27.72 | 27.63 | 44.26 | 35.52 | 22.86 | 16.45 |
P/E links to full P/E history page with 30-year chart
Enterprise-value multiples — capital-structure-neutral measures of total business value
AstraZeneca PLC's enterprise value stands at 15.2x EBITDA, 32% below its 5-year average of 22.2x. The Healthcare sector median is 14.2x, placing the stock at a 7% premium on an enterprise-value basis.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| EV / Revenue | — | 5.08 | 4.21 | 5.08 | 5.31 | 5.07 | 5.45 | 5.92 | 4.86 | 4.29 | 3.48 |
| EV / EBITDA | 15.16 | 15.31 | 15.12 | 17.73 | 26.13 | 36.77 | 18.01 | 21.58 | 15.03 | 14.34 | 11.02 |
| EV / EBIT | 21.48 | 21.15 | 21.96 | 27.43 | 61.47 | 187.61 | 27.98 | 48.90 | 31.94 | 26.84 | 16.26 |
| EV / FCF | — | 25.34 | 31.31 | 35.45 | 32.54 | 50.41 | 66.19 | 283.42 | 86.03 | 49.17 | 43.69 |
Margins and return-on-capital ratios measuring operating efficiency
AstraZeneca PLC earns an operating margin of 23.4%. Operating margins have expanded from 17.9% to 23.4% over the past 3 years, signaling improving operational efficiency. ROE of 22.9% indicates solid capital efficiency. ROIC of 14.9% represents solid returns on invested capital.
Full margin charts and quarterly trend are on the Earnings History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gross Margin | 81.9% | 81.9% | 81.1% | 82.0% | 72.1% | 66.8% | 80.1% | 79.8% | 77.7% | 80.8% | 82.1% |
| Operating Margin | 23.4% | 23.4% | 18.5% | 17.9% | 8.5% | 2.8% | 19.4% | 12.0% | 15.3% | 16.4% | 21.3% |
| Net Profit Margin | 17.5% | 17.5% | 13.0% | 13.0% | 7.4% | 0.3% | 12.0% | 5.5% | 9.8% | 13.4% | 15.2% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| ROE | 22.9% | 22.9% | 17.6% | 15.6% | 8.6% | 0.4% | 21.1% | 9.3% | 14.0% | 18.0% | 19.9% |
| ROA | 9.4% | 9.4% | 6.9% | 6.0% | 3.3% | 0.1% | 5.0% | 2.2% | 3.5% | 4.8% | 5.7% |
| ROIC | 14.9% | 14.9% | 11.8% | 10.1% | 4.6% | 1.7% | 13.9% | 7.9% | 8.5% | 9.3% | 13.2% |
| ROCE | 17.2% | 17.2% | 13.6% | 11.6% | 4.9% | 1.6% | 11.5% | 6.7% | 7.4% | 7.8% | 10.6% |
Solvency and debt-coverage ratios — lower is generally safer
AstraZeneca PLC carries a Debt/EBITDA ratio of 1.5x, which is manageable (53% below the sector average of 3.2x). Net debt stands at $24.0B ($29.7B total debt minus $5.7B cash). Interest coverage of 8.3x is adequate, though a cyclical earnings downturn could tighten the margin of safety.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Debt / Equity | 0.61 | 0.61 | 0.74 | 0.73 | 0.79 | 0.78 | 1.30 | 1.25 | 1.36 | 1.07 | 1.01 |
| Debt / EBITDA | 1.53 | 1.53 | 2.00 | 2.18 | 3.23 | 5.95 | 2.53 | 2.73 | 2.68 | 2.65 | 2.32 |
| Net Debt / Equity | — | 0.49 | 0.60 | 0.58 | 0.62 | 0.62 | 0.80 | 0.88 | 1.02 | 0.87 | 0.71 |
| Net Debt / EBITDA | 1.23 | 1.23 | 1.63 | 1.74 | 2.55 | 4.72 | 1.56 | 1.92 | 2.00 | 2.16 | 1.62 |
| Debt / FCF | — | 2.04 | 3.39 | 3.47 | 3.17 | 6.47 | 5.72 | 25.26 | 11.45 | 7.40 | 6.44 |
| Interest Coverage | 8.32 | 8.32 | 6.17 | 5.34 | 2.88 | 0.79 | 4.08 | 2.10 | 2.46 | 2.64 | 3.60 |
Short-term solvency ratios and asset-utilisation metrics
The current ratio of 0.94x is below 1.0, meaning current liabilities exceed current assets — though the company's $5.7B cash position helps mitigate short-term liquidity concerns. The current ratio has improved from 0.82x to 0.94x over the past 3 years.
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Current Ratio | 0.94 | 0.94 | 0.93 | 0.82 | 0.86 | 1.16 | 0.96 | 0.86 | 0.96 | 0.80 | 0.87 |
| Quick Ratio | 0.72 | 0.72 | 0.74 | 0.64 | 0.68 | 0.76 | 0.76 | 0.68 | 0.78 | 0.62 | 0.72 |
| Cash Ratio | 0.19 | 0.19 | 0.20 | 0.19 | 0.24 | 0.28 | 0.39 | 0.34 | 0.35 | 0.28 | 0.39 |
| Asset Turnover | — | 0.51 | 0.52 | 0.45 | 0.46 | 0.36 | 0.40 | 0.40 | 0.36 | 0.35 | 0.37 |
| Inventory Turnover | 1.62 | 1.62 | 1.93 | 1.52 | 2.64 | 1.38 | 1.32 | 1.54 | 1.71 | 1.42 | 1.77 |
| Days Sales Outstanding | — | 94.31 | 75.84 | 66.98 | 75.65 | 79.33 | 77.49 | 73.29 | 49.49 | 45.53 | 40.99 |
Earnings, FCF, buyback, and dividend yields — total returns to shareholders
AstraZeneca PLC returns 2.1% to shareholders annually — split between a 1.9% dividend yield and 0.3% buyback yield. A payout ratio of 49.6% is moderate and appears sustainable, balancing shareholder returns with reinvestment capacity. The earnings yield of 3.7% (inverse of P/E) provides a useful comparison to bond yields when assessing the stock's relative attractiveness to fixed income.
Full dividend history and growth charts are on the Dividend History page
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Dividend Yield | 1.9% | 1.9% | 2.3% | 2.1% | 2.1% | 2.3% | 2.7% | 2.7% | 3.7% | 4.3% | 5.2% |
| Payout Ratio | 49.6% | 49.6% | 65.8% | 75.2% | 132.7% | 3442.9% | 111.8% | 269.1% | 161.7% | 117.3% | 101.8% |
| Metric | TTM | FY 2025 | FY 2024 | FY 2023 | FY 2022 | FY 2021 | FY 2020 | FY 2019 | FY 2018 | FY 2017 | FY 2016 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Earnings Yield | 3.7% | 3.7% | 1.7% | 2.8% | 1.5% | 0.1% | 2.4% | 1.0% | 2.3% | 3.7% | 5.1% |
| FCF Yield | 4.3% | 4.3% | 3.6% | 3.1% | 3.4% | 2.3% | 1.7% | 0.4% | 1.3% | 2.4% | 2.7% |
| Buyback Yield | 0.3% | 0.3% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% | 0.0% |
| Total Shareholder Yield | 2.1% | 2.1% | 2.3% | 2.1% | 2.1% | 2.3% | 2.7% | 2.7% | 3.7% | 4.3% | 5.2% |
| Shares Outstanding | — | $1.6B | $1.6B | $1.6B | $1.6B | $1.4B | $1.3B | $1.3B | $1.3B | $1.3B | $1.3B |
Compare AZN with 10 similar companies in its peer group
| Company | Market Cap | P/E | EV/EBITDA | P/FCF | Gross Margin | Op Margin | ROE | ROIC | Debt/EBITDA |
|---|---|---|---|---|---|---|---|---|---|
| $271B | 26.7 | 15.2 | 23.1 | 81.9% | 23.4% | 22.9% | 14.9% | 1.5 | |
| $143B | 18.5 | 10.3 | 15.8 | 70.3% | 24.7% | 8.9% | 7.5% | 3.3 | |
| $281B | 15.6 | 10.8 | 22.8 | 72.0% | 36.2% | 36.9% | 22.0% | 1.7 | |
| $1.0T | 47.8 | 34.3 | 115.6 | 83.8% | 45.6% | 101.2% | 41.8% | 1.4 | |
| $110B | 15.7 | 8.9 | 8.6 | 67.6% | 26.3% | 40.4% | 16.9% | 2.8 | |
| $383B | 91.4 | 15.8 | 21.5 | 70.2% | 32.8% | 6214.7% | 23.9% | 2.4 | |
| $281B | 20.5 | 13.7 | 15.9 | 75.0% | 31.2% | 31.0% | 18.8% | 1.7 | |
| $102B | 18.2 | 10.8 | 10.1 | 72.3% | 13.6% | 10.4% | 5.5% | 2.3 | |
| $154B | 18.3 | 11.8 | 16.2 | 78.8% | 39.7% | 40.7% | 23.2% | 1.7 | |
| $63B | 14.7 | 15.3 | 15.5 | 85.4% | 24.9% | 14.9% | 8.9% | 0.7 | |
| $29B | 22.3 | 11.7 | 14.2 | 70.5% | 19.1% | 7.4% | 6.5% | 2.5 | |
| Healthcare Median | — | 22.1 | 14.2 | 18.5 | 63.9% | -4.3% | -32.6% | -11.6% | 3.2 |
Peer selection based on competitive and market overlap. Compare multiple stocks →
Includes 30+ ratios · 30 years · Updated daily
Deep dive into AZN consensus models and risk factors.
Wall Street verdict, signals, and target summaries.
DCF models, multiple analysis, and analyst estimates.
10-year return with dividends reinvested.
See how regular investing compounds over time.
Compare growth, multiples, and margins vs sector.
Quick answers to the most common questions about buying AZN stock.
AstraZeneca PLC's current P/E ratio is 26.7x. The historical average is 24.9x. This places it at the 59th percentile of its historical range.
AstraZeneca PLC's current EV/EBITDA is 15.2x. This enterprise value multiple compares the company's total value (equity + debt - cash) to its EBITDA. The historical average is 11.1x.
AstraZeneca PLC's return on equity (ROE) is 22.9%. This is above the typical threshold of 15-20% considered good for most companies. The historical average is 24.1%.
Based on historical data, AstraZeneca PLC is trading at a P/E of 26.7x. This is at the 59th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.
AstraZeneca PLC's current dividend yield is 1.86% with a payout ratio of 49.6%.
AstraZeneca PLC has 81.9% gross margin and 23.4% operating margin. Operating margin above 20% indicates strong pricing power and cost efficiency.
AstraZeneca PLC's Debt/EBITDA ratio is 1.5x, indicating moderate leverage. A ratio below 2x is generally considered financially healthy.