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CANFCan-Fite BioPharma Ltd.
$2.83$21M
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Can-Fite BioPharma Ltd. (CANF) Financial Ratios

Latest Ratios: P/E Ratio -2.6x · EV/EBITDA N/A · ROE -134.9%. (2011–2024 historical series)

Income StatementBalance SheetCash FlowRatios
AnnualQuarterly

CANF Valuation Multiples

Price-based multiples — how expensive the stock is relative to earnings, sales, book value, and cash flow

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
Market Cap$21M$12M$9M$17M$24M$21M$9M$25M$24M$33M$34M
Enterprise Value$16M$7M$5M$14M$20M$13M$7M$21M$21M$25M$17M
P/E Ratio →-2.62——————————
P/S Ratio30.4517.5412.6220.5827.8827.874.656.4228.49194.42203.45
P/B Ratio3.782.171.503.731.653.503.878.137.888.513.21
P/FCF———————————
P/OCF———————————

P/E links to full P/E history page with 30-year chart

CANF EV Ratios

Enterprise-value multiples — capital-structure-neutral measures of total business value

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
EV / Revenue—10.546.9116.9822.8817.123.365.4724.35146.56100.76
EV / EBITDA———————————
EV / EBIT———————————
EV / FCF———————————

CANF Profitability

Margins and return-on-capital ratios measuring operating efficiency

Margins

Full margin charts and quarterly trend are on the Earnings History page

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
Gross Margin100.0%100.0%100.0%100.0%100.0%100.0%100.0%100.0%100.0%100.0%100.0%
Operating Margin-1206.2%-1206.2%-1103.0%-1246.4%-1505.5%-1853.1%-590.9%-141.7%-873.1%-5093.7%-3894.6%
Net Profit Margin-1169.1%-1169.1%-1027.5%-1255.9%-1476.6%-1892.9%-621.3%-172.0%-588.2%-4069.3%-2912.3%

Return on Capital

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
ROE-134.9%-134.9%-142.5%-107.9%-123.1%-339.2%-462.7%-216.5%-143.4%-96.3%-55.5%
ROA-82.5%-82.5%-79.2%-68.9%-84.6%-163.2%-156.6%-83.3%-55.2%-49.7%-34.5%
ROIC-448.3%-448.3%-345.2%-129.7%-241.1%——————
ROCE-108.1%-108.1%-111.1%-83.1%-99.6%-214.9%-246.7%-99.6%-107.7%-73.5%-52.3%

CANF Leverage & Debt

Solvency and debt-coverage ratios — lower is generally safer

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
Debt / Equity0.020.020.010.010.010.010.03————
Debt / EBITDA———————————
Net Debt / Equity—-0.87-0.68-0.65-0.30-1.35-1.07-1.20-1.15-2.09-1.62
Net Debt / EBITDA———————————
Debt / FCF———————————
Interest Coverage-580.71-580.71-585.36-631.04-713.44-36.53-26.80-300.78-263.42-315.66-11.37

Net cash position: cash ($5M) exceeds total debt ($104000)

CANF Liquidity & Efficiency

Short-term solvency ratios and asset-utilisation metrics

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
Current Ratio4.384.384.903.667.357.412.182.533.824.049.86
Quick Ratio4.384.384.903.687.377.412.402.535.664.0410.21
Cash Ratio3.843.844.423.197.016.570.841.251.953.249.52
Asset Turnover—0.070.070.090.040.080.250.480.110.020.01
Inventory Turnover———————————
Days Sales Outstanding—41.7038.3221.1820.548.61114.42——47.02137.37

CANF Shareholder Yields

Earnings, FCF, buyback, and dividend yields — total returns to shareholders

Dividends

Full dividend history and growth charts are on the Dividend History page

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
Dividend Yield———————————
Payout Ratio———————————

Total Shareholder Return Metrics

MetricTTMFY 2024FY 2023FY 2022FY 2021FY 2020FY 2019FY 2018FY 2017FY 2016FY 2015
Earnings Yield———————————
FCF Yield———————————
Buyback Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Total Shareholder Yield0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%0.0%
Shares Outstanding—$7M$4M$3M$2M$1M$286366$129674$108417$92308$76510

Key Metrics

Growth RegimeContracting
ProfitabilityNegative
Balance SheetVulnerable
Cash FlowBurning
Top Statement Risk

Liquidity and dilution risk

Distressed Valuation Reflects Pipeline Uncertainty

According to recent market data, CANF trades at a price-to-sales ratio of 29.59, a multiple that appears disconnected from fundamental performance and suggests investors are pricing in speculative binary outcomes rather than current revenue, which remains negligible and highly volatile due to its reliance on milestone payments.

The elevated P/S ratio relative to the broader biotech sector indicates that the market is assigning value to the potential of the A3AR platform rather than existing cash flows. This valuation is inherently fragile, as any delay in clinical milestones or regulatory setbacks could lead to a rapid compression of multiples as the market recalibrates for dilution risk.

Capital Compounding Remains Fundamentally Negative

Based on reported financial statements, the company's ROIC has trended into negative territory, reaching -2.1% in 2024Q4, which highlights a persistent inability to generate returns on invested capital as research expenditures continue to outpace the sporadic and non-recurring revenue generated from licensing agreements.

The negative ROIC trend underscores the structural challenge of a pre-commercial biotech firm where capital is consumed by long-cycle R&D without immediate commercialization. Investors should monitor whether the company can achieve a positive inflection point in capital efficiency as it approaches potential regulatory approval for its lead assets.

Liquidity Buffer Faces Significant Pressure

As reported in recent SEC filings, the company's current ratio has fluctuated, settling at 3.60 in 2025Q2, yet this metric may provide a false sense of security given the high cash burn rate and the absence of recurring revenue to support ongoing operational requirements.

While the current ratio appears adequate on the surface, the lack of liquid, recurring cash inflows means the company remains highly dependent on external financing. The rapid erosion of the asset base suggests that the current liquidity position is insufficient to sustain long-term operations without further dilutive capital raises.

Misapplication of Traditional Revenue Multiples

Based on an analysis of the business model, the price-to-sales ratio is the most commonly misapplied metric for CANF, as it obscures the reality that current revenue is derived from one-time milestones rather than sustainable, recurring product sales or predictable market demand.

Using P/S to value this firm ignores the 'lumpiness' of milestone-based income, which does not reflect the underlying health of the commercial pipeline. Analysts should instead focus on the cash runway and the probability-adjusted net present value of the clinical assets to better assess the firm's true economic worth.

Download Financial Ratios Data

Includes 30+ ratios · 14 years · Updated daily

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CANF — Frequently Asked Questions

Quick answers to the most common questions about buying CANF stock.

What is Can-Fite BioPharma Ltd.'s P/E ratio?

Can-Fite BioPharma Ltd.'s current P/E ratio is -2.6x. This places it at the 50th percentile of its historical range.

What is Can-Fite BioPharma Ltd.'s ROE?

Can-Fite BioPharma Ltd.'s return on equity (ROE) is -134.9%. The historical average is -215.0%.

Is CANF stock overvalued?

Based on historical data, Can-Fite BioPharma Ltd. is trading at a P/E of -2.6x. This is at the 50th percentile of its historical P/E range. Compare with industry peers and growth rates for a complete picture.

What are Can-Fite BioPharma Ltd.'s profit margins?

Can-Fite BioPharma Ltd. has 100.0% gross margin and -1206.2% operating margin.