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DSGNDesign Therapeutics, Inc.
$12.36$772M
Overview & Tools
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DSGN logo

Design Therapeutics, Inc.

DSGN
NASDAQ · Biotechnology
$12.36
At close - Sep 23, 4:00 PM EDT - USD
Market Cap$772M
P/E-10.1x
52W High$17.25
Volume738.22K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Cash Runway Crunch Undermines Gene Therapy Ambitions

Design Therapeutics is a pre-revenue biotech focused on Friedreich's ataxia, with its lead candidate DT-216 undergoing a pivotal Phase 1 trial. The company's fundamental outlook hinges on successful clinical execution, but its financial position is precarious:...

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsMixed
Explore valuation models
MARKET ACTION

DSGN price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

10/12 Beats

EPS beat 10 of last 12 quarters

02

Valuation risk

-142% Peers

P/E is 142% below peer median

03

Market leadership

RS 64 · Avg

Average momentum (RS Rating: 64)

04

Mixed Trend

Mixed

Price < 50DMA but > 200DMA

Next CatalystEstimated earnings · Nov 3

Market performance

Price History →

Trailing total returns as of 9/24/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
DSGN+35.82%
S&P 500 (^GSPC)+12.39%
1-Year Return
DSGN+105.32%
S&P 500 (^GSPC)+15.77%
3-Year Return
DSGN+420.42%
S&P 500 (^GSPC)+64.58%
5-Year Return
DSGN-18.74%
S&P 500 (^GSPC)+62.25%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$70M-40.7% YoY
Free cash flow
-$55M-25.6% YoY
Operating margin
-
ROIC (TTM)-28.4%
Avg ROIC 5Y-
ROE (TTM)-30.7%
Piotroski Score2 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate10/12 (83%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 3, 2026
-$0.32+7.1%
vs -$0.34
—
vs —
Q2 2026
Apr 28, 2026
-$0.29+19.4%
vs -$0.36
—
vs —
Q2 2026
Mar 9, 2026
-$0.27+28.9%
vs -$0.38
—
vs —
Q4 2025
Nov 5, 2025
-$0.30+11.8%
vs -$0.34
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Defense World·Sep 10, 2026
Bank of New York Mellon Corp Purchases New Stake in Design Therapeutics, Inc. $DSGN

Bank of New York Mellon Corp acquired a new position in shares of Design Therapeutics, Inc. (NASDAQ: DSGN) in the undefined quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The fund acquired 92,069 shares of the company's stock, valued at approximately $1,332,000. Bank of New York

GlobeNewsWire·Sep 2, 2026
Design Therapeutics to Participate in 2026 Cantor Fitzgerald Global Healthcare Conference

CARLSBAD, Calif., Sept. 02, 2026 (GLOBE NEWSWIRE) -- Design Therapeutics, Inc. (Nasdaq: DSGN), a clinical-stage biotechnology company developing treatments for serious degenerative genetic diseases, today announced that management will participate in a fireside chat during the 2026 Cantor Fitzgerald Global Healthcare Conference on Wednesday, September 9, 2026, at 2:45 p.m.

Defense World·Sep 2, 2026
BlackRock Inc. Takes Position in Design Therapeutics, Inc. $DSGN

BlackRock Inc. acquired a new position in Design Therapeutics, Inc. (NASDAQ: DSGN) during the undefined quarter, according to the company in its most recent 13F filing with the Securities and Exchange Commission (SEC). The firm acquired 2,660,024 shares of the company's stock, valued at approximately $38,491,000. BlackRock Inc. owned about 4.25% of Design

24/7 Wall Street·Aug 27, 2026
Wall Street Moves on MAA, Rivian and Design Therapeutics: One Upgrade, One Target Trim and a Biotech on Watch

An EV maker on the rebound, a Sun Belt landlord facing fresh headwinds, and a clinical-stage biotech sitting on pivotal pipeline data have all landed on analysts' radars this week for very different reasons.

Filtered for Design Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark DSGN against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Design Therapeutics, Inc. (DSGN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
DSGN logoDSGNDesign Therapeutics, Inc.Current
$12.36$771.97M-10.13——-30.7%—
FULC logoFULCFulcrum Therapeutics, Inc.
$3.81$206.16M-3.23-100%—-28.54%—
EXAS logoEXASExact Sciences Corporation
$104.91$20.02B-95.3717.69%-6.4%-8.66%—
IMVT logoIMVTImmunovant, Inc.
$34.54$7.13B-12.47—-7585.86%-69.59%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$26.38$3.3B-202.9291.34%6.15%15.05%—
BEAM logoBEAMBeam Therapeutics Inc.
$24.37$2.51B-30.09120.01%-54.75%-7.7%—

Compare DSGN vs Peers

Design Therapeutics, Inc. (DSGN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs FULC

Most directly comparable listed peer for DSGN.

Scale Benchmark

vs TMO

Larger-name benchmark to compare DSGN against a more recognizable public peer.

Peer Set

Compare Top 5

vs FULC, EXAS, IMVT, ARQT

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

DSGN SEC Filings & Documents

Design Therapeutics, Inc. (DSGN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 3, 2026·SEC

Material company update

Jun 11, 2026·SEC

Material company update

May 18, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 9, 2026·SEC

FY 2025

Mar 10, 2025·SEC

FY 2024

Mar 19, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 3, 2026·SEC

FY 2026

Apr 28, 2026·SEC

FY 2025

Nov 5, 2025·SEC

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DSGN Frequently Asked Questions

Design Therapeutics, Inc. (DSGN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is DSGN profitable?

Design Therapeutics, Inc. (DSGN) reported a net loss of $70.8M for fiscal year 2025.

Dividend & Returns
What is DSGN's return on equity?

Design Therapeutics, Inc. (DSGN) has a return on equity (ROE) of -30.7%. Negative ROE indicates the company is unprofitable.

What is Design Therapeutics, Inc.'s free cash flow?

Design Therapeutics, Inc. (DSGN) had negative free cash flow of $55.1M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in DSGN back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →