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DSGN
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DSGNDesign Therapeutics, Inc.
$10.21$638M
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DSGN logo

Design Therapeutics, Inc.

DSGN
NASDAQ · Rare Disease Biotech
$10.21
At close - Nov 6, 4:00 PM EST - USD
Market Cap$638M
P/E-8.7x
52W High$17.25
Volume330.61K
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Cash Runway Crunch Undermines Gene Therapy Ambitions

Design Therapeutics is a pre-revenue biotech focused on Friedreich's ataxia, with its lead candidate DT-216 undergoing a pivotal Phase 1 trial. The company's fundamental outlook hinges on successful clinical execution, but its financial position is precarious: cash of $12.9M as of 2026Q2 implies less than one quarter…

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

DSGN price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

10/12 Beats

EPS beat 10 of last 12 quarters

02

Valuation risk

-124% Peers

P/E is 124% below peer median

03

Market leadership

RS 28 · Lag

Laggard (Underperforming 72% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 4

Market performance

Price History →

Trailing total returns as of 11/8/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
DSGN+12.20%
S&P 500 (^GSPC)+7.63%
1-Year Return
DSGN+48.62%
S&P 500 (^GSPC)+9.69%
3-Year Return
DSGN+379.34%
S&P 500 (^GSPC)+81.96%
5-Year Return
DSGN-43.50%
S&P 500 (^GSPC)+63.83%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$70M-40.7% YoY
Free cash flow FY25
-$55M-25.6% YoY
Operating margin FY25
-
ROIC (FY25)-28.4%
Avg ROIC 5Y-33.5%
ROE (TTM)-35.5%
Piotroski Score2 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate10/12 (83%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 4, 2026
-$0.32+7.0%
vs -$0.34
—
vs —
Q3 2026
Aug 3, 2026
-$0.32+7.1%
vs -$0.34
—
vs —
Q2 2026
Apr 28, 2026
-$0.29+19.4%
vs -$0.36
—
vs —
Q2 2026
Mar 9, 2026
-$0.27+28.9%
vs -$0.38
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
GlobeNewsWire·3d ago
Design Therapeutics Announces Third Quarter 2026 Financial Results and Recent Business Updates

DT-216P2 Anticipated Milestones: Registrational Plan Update in Q4 2026 and 12-Week RESTORE-FA Data in Q1 2027 Cash and securities of $208.6 million at quarter-end provide strong financial runway CARLSBAD, Calif., Nov. 04, 2026 (GLOBE NEWSWIRE) -- Design Therapeutics, Inc. (Nasdaq: DSGN), a clinical-stage biotechnology company developing treatments for serious degenerative genetic diseases, today reported third quarter 2026 financial results and highlighted business updates and upcoming milestones across its GeneTAC® portfolio.

Seeking Alpha·Oct 4, 2026
Design Therapeutics: 'Hold' DT-216P2 Registrational FA Plans Q4 2026 And 12-Week Results Q1 2027

Design Therapeutics is initiated with a "Hold" rating as its lead candidate, DT-216P2 targets the root cause of Friedreich Ataxia [FA]. The company's 4-week phase 1/2 RESTORE-FA data showed strong biomarker and clinical improvements, but confirmation awaits 12-week results in Q1 2027. Upcoming catalysts include a registrational update in Q4 2026 for DT-216P2 FA and early-stage readouts for DM1 and FECD programs in 2027.

Defense World·Sep 30, 2026
Design Therapeutics, Inc. (NASDAQ:DSGN) Stock Now Rated “Moderate Buy” by Sell-Side Analysts

Design Therapeutics, Inc. (NASDAQ: DSGN - Get Free Report) has received an average recommendation of "Moderate Buy" from the eight research firms that are presently covering the company, MarketBeat reports. One equities research analyst has rated the stock with a sell recommendation, six have assigned a buy recommendation and one has assigned a strong buy recommendation

Defense World·Sep 10, 2026
Bank of New York Mellon Corp Purchases New Stake in Design Therapeutics, Inc. $DSGN

Bank of New York Mellon Corp acquired a new position in shares of Design Therapeutics, Inc. (NASDAQ: DSGN) in the undefined quarter, according to its most recent Form 13F filing with the Securities and Exchange Commission. The fund acquired 92,069 shares of the company's stock, valued at approximately $1,332,000. Bank of New York

Filtered for Design Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark DSGN against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Design Therapeutics, Inc. (DSGN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
DSGN logoDSGNDesign Therapeutics, Inc.Current
$10.21$637.69M-8.69——-35.51%—
FULC logoFULCFulcrum Therapeutics, Inc.
$3.70$200.21M-3.32-100%—-28.54%—
IMVT logoIMVTImmunovant, Inc.
$30.53$6.3B-11.66—-7585.86%-69.59%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$25.55$3.2B116.8891.34%5.88%14.18%—
BEAM logoBEAMBeam Therapeutics Inc.
$26.41$2.72B-25.82120.01%-73.04%-9.69%—
EDIT logoEDITEditas Medicine, Inc.
$2.57$394.4M-4.1525.39%-157.32%-196.63%—

Compare DSGN vs Peers

Design Therapeutics, Inc. (DSGN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs FULC

Most directly comparable listed peer for DSGN.

Scale Benchmark

vs TMO

Larger-name benchmark to compare DSGN against a more recognizable public peer.

Peer Set

Compare Top 5

vs FULC, IMVT, ARQT, BEAM

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

DSGN SEC Filings & Documents

Design Therapeutics, Inc. (DSGN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 3, 2026·SEC

Material company update

Jun 11, 2026·SEC

Material company update

May 18, 2026·SEC

10-K Annual Reports

4
FY 2026

Mar 9, 2026·SEC

FY 2025

Mar 10, 2025·SEC

FY 2024

Mar 19, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 3, 2026·SEC

FY 2026

Apr 28, 2026·SEC

FY 2025

Nov 5, 2025·SEC

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DSGN Frequently Asked Questions

Design Therapeutics, Inc. (DSGN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is DSGN profitable?

No. Design Therapeutics, Inc. (DSGN) reported a net loss of $74.1M over the trailing twelve months.

Dividend & Returns
What is DSGN's return on equity?

Design Therapeutics, Inc. (DSGN) had a return on equity (ROE) of -35.5% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Design Therapeutics, Inc.'s free cash flow?

Design Therapeutics, Inc. (DSGN) had negative free cash flow of $59.4M over the trailing twelve months.

What if you invested $1,000 in DSGN back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →