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DYNDyne Therapeutics, Inc.
$18.07$3.4B
Overview & Tools
OverviewChart Terminal ↗Visualize
Valuation & Forecasts
Valuation ModelsEstimatesDCF Model
Price & Analyst Data
Analyst TargetsPrice History
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DYN logo

Dyne Therapeutics, Inc.

DYN
NASDAQ · Cell & Gene Therapy
$18.07
At close - Nov 6, 4:00 PM EST - USD
Market Cap$3.37B
P/E-5.4x
52W High$27.31
Volume2.36M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Accelerating R&D Burn Challenges Five-Quarter Cash Runway

Dyne Therapeutics is a pre-revenue clinical-stage biotech advancing muscle disease therapies, with R&D spending surging 51% sequentially to $152.2M in Q2 2026 as it prepares for BLA submission and expanded trials.

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

DYN price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-115% Peers

P/E is 115% below peer median

03

Market leadership

RS 45 · Lag

Laggard (Underperforming 55% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Feb 5

Market performance

Price History →

Trailing total returns as of 11/7/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
DYN-2.32%
S&P 500 (^GSPC)+7.63%
1-Year Return
DYN-0.71%
S&P 500 (^GSPC)+9.69%
3-Year Return
DYN+121.45%
S&P 500 (^GSPC)+76.23%
5-Year Return
DYN+18.49%
S&P 500 (^GSPC)+62.81%

Growth & profitability

Annual revenue & EPS trend
Revenue FY25
-
Net income FY25
-$446M-40.6% YoY
Free cash flow FY25
-$405M-37.4% YoY
Operating margin FY25
-
ROIC (FY25)-221.2%
Avg ROIC 5Y-194.7%
ROE (TTM)-69.7%
Piotroski Score4 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q4 2026Latest
Nov 5, 2026
-$1.06-16.8%
vs -$0.91
—
vs —
Q3 2026
Jul 30, 2026
-$1.08-44.2%
vs -$0.75
—
vs —
Q2 2026
May 11, 2026
-$0.73+5.5%
vs -$0.77
—
vs —
Q2 2026
Mar 2, 2026
-$0.76-2.7%
vs -$0.74
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

4 Stories
GlobeNewsWire·2d ago
Dyne Therapeutics Reports Third Quarter 2026 Financial Results and Recent Business Highlights

- Biologics License Application (BLA) for z-rostudirsen in exon 51 Duchenne muscular dystrophy (DMD) under priority review by FDA; PDUFA target action date of January 21, 2027 -

GlobeNewsWire·Oct 22, 2026
Dyne Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

WALTHAM, Mass., Oct. 22, 2026 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (Nasdaq: DYN), a clinical-stage company focused on delivering functional improvement for people living with genetically driven neuromuscular diseases, today announced that it has granted inducement equity awards to 16 newly hired employees. The awards were made as an inducement material to the newly hired employees' acceptance of employment with Dyne in accordance with Nasdaq Listing Rule 5635(c)(4).

GlobeNewsWire·Sep 29, 2026
Dyne Therapeutics Announces Additional One-Year Clinical Data from Phase 1/2 ACHIEVE Trial of Z-Basivarsen (DYNE-101) for Myotonic Dystrophy Type 1 (DM1)

- Data from a pooled dose group of participants initially enrolled in the multiple ascending dose (MAD) portion of ACHIEVE showed functional improvement versus baseline, versus placebo and versus a matched natural history cohort across multiple measures at 12 months -

Seeking Alpha·Sep 14, 2026
Dyne Therapeutics, Inc. (DYN) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Dyne Therapeutics, Inc. (DYN) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Filtered for Dyne Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark DYN against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Dyne Therapeutics, Inc. (DYN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
DYN logoDYNDyne Therapeutics, Inc.Current
$18.07$3.37B-5.43——-69.73%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$17.82$1.88B127.9315.58%0.75%1.04%—
CRSP logoCRSPCRISPR Therapeutics AG
$50.07$4.83B-10.62-89.97%-1812.07%-25.59%—
BMRN logoBMRNBioMarin Pharmaceutical Inc.
$56.03$10.83B-567.6812.87%-0.52%-0.31%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$15.43$1.52B-3.0120.13%-71.78%——
IONS logoIONSIonis Pharmaceuticals, Inc.
$39.42$6.55B-11.5533.87%-64.64%-110.84%—

Compare DYN vs Peers

Dyne Therapeutics, Inc. (DYN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for DYN.

Scale Benchmark

vs LLY

Larger-name benchmark to compare DYN against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, CRSP, BMRN, RARE

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

DYN SEC Filings & Documents

Dyne Therapeutics, Inc. (DYN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 29, 2026·SEC

Material company update

Jul 22, 2026·SEC

Material company update

Jul 20, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 2, 2026·SEC

FY 2025

Feb 27, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Jul 29, 2026·SEC

FY 2026

May 11, 2026·SEC

FY 2025

Nov 5, 2025·SEC

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DYN Frequently Asked Questions

Dyne Therapeutics, Inc. (DYN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is DYN profitable?

No. Dyne Therapeutics, Inc. (DYN) reported a net loss of $604.9M over the trailing twelve months.

Dividend & Returns
What is DYN's return on equity?

Dyne Therapeutics, Inc. (DYN) had a return on equity (ROE) of -69.7% over the trailing twelve months. A negative ROE means the company lost money over the period.

What is Dyne Therapeutics, Inc.'s free cash flow?

Dyne Therapeutics, Inc. (DYN) had negative free cash flow of $568.8M over the trailing twelve months.

What if you invested $1,000 in DYN back in 2007?

Total return calculator · dividends reinvested · 19+ years of data

See returns →