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DYNDyne Therapeutics, Inc.
$17.14$3.2B
Overview & Tools
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DYN logo

Dyne Therapeutics, Inc.

DYN
NASDAQ · Biotechnology
$17.14
At close - Sep 22, 4:00 PM EDT - USD
Market Cap$3.2B
P/E-4.9x
52W High$27.31
Volume2.63M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Accelerating R&D Burn Challenges Five-Quarter Cash Runway

Dyne Therapeutics is a pre-revenue clinical-stage biotech advancing muscle disease therapies, with R&D spending surging 51% sequentially to $152.2M in Q2 2026 as it prepares for BLA submission and expanded trials. The company holds a healthy balance sheet with...

GrowthMixed
ProfitabilityNegative
ValuationReview
TechnicalsWeak
Explore valuation models
MARKET ACTION

DYN price & volume

Price trend, volume and key moving averages

Launch Terminal
Loading chart...
Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

5/12 Beats

EPS beat 5 of last 12 quarters

02

Valuation risk

-114% Peers

P/E is 114% below peer median

03

Market leadership

RS 28 · Lag

Laggard (Underperforming 72% of market)

04

Weak Trend

Below 200DMA

Price < 200DMA

Next CatalystEstimated earnings · Oct 30

Market performance

Price History →

Trailing total returns as of 9/23/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
DYN-7.35%
S&P 500 (^GSPC)+13.20%
1-Year Return
DYN+27.53%
S&P 500 (^GSPC)+15.98%
3-Year Return
DYN+88.56%
S&P 500 (^GSPC)+83.49%
5-Year Return
DYN+6.33%
S&P 500 (^GSPC)+77.11%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$446M-40.6% YoY
Free cash flow
-$405M-37.4% YoY
Operating margin
-
ROIC (TTM)-221.2%
Avg ROIC 5Y-
ROE (TTM)-55.7%
Piotroski Score4 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate5/12 (42%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Jul 30, 2026
-$1.08-44.2%
vs -$0.75
—
vs —
Q2 2026
May 11, 2026
-$0.73+5.5%
vs -$0.77
—
vs —
Q2 2026
Mar 2, 2026
-$0.76-2.7%
vs -$0.74
—
vs —
Q4 2025
Nov 5, 2025
-$0.76+6.2%
vs -$0.81
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
GlobeNewsWire·6d ago
Dyne Therapeutics Reports Inducement Grants Under Nasdaq Listing Rule 5635(c)(4)

WALTHAM, Mass., Sept. 17, 2026 (GLOBE NEWSWIRE) -- Dyne Therapeutics, Inc. (Nasdaq: DYN), a clinical-stage company focused on delivering functional improvement for people living with genetically driven neuromuscular diseases, today announced that it has granted inducement equity awards to 14 newly hired employees. The awards were made as an inducement material to the newly hired employees' acceptance of employment with Dyne in accordance with Nasdaq Listing Rule 5635(c)(4).

Seeking Alpha·Sep 14, 2026
Dyne Therapeutics, Inc. (DYN) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Dyne Therapeutics, Inc. (DYN) Presents at Morgan Stanley 24th Annual Global Healthcare Conference Transcript

Seeking Alpha·Sep 9, 2026
Dyne Therapeutics Remains A Buy Even As Novartis Trial Failure Hits DM1 Class

Dyne Therapeutics remains a Buy despite a 16% selloff triggered by Novartis' DM1 trial failure, which heightened platform-wide clinical risk perceptions. The Novartis HARBOR trial failure challenges the core RNA-targeting therapeutic thesis, raising doubts about translating biomarker gains into functional benefit for DYN's DM1 and DMD programs. DYN's lead asset, z-rostudirsen, faces regulatory and confirmatory risks, with FDA approval likely but long-term value now more uncertain due to functional outcome concerns.

Defense World·Sep 9, 2026
Stock Traders Buy High Volume of Dyne Therapeutics Call Options (NASDAQ:DYN)

Dyne Therapeutics, Inc. (NASDAQ: DYN - Get Free Report) saw unusually large options trading activity on Tuesday. Stock investors bought 20,532 call options on the stock. This is an increase of 4,325% compared to the average volume of 464 call options. Insider Activity In other Dyne Therapeutics news, CEO John Cox sold 5,658 shares of the

Filtered for Dyne Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark DYN against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Dyne Therapeutics, Inc. (DYN)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
DYN logoDYNDyne Therapeutics, Inc.Current
$17.14$3.2B-4.94——-55.71%—
SRPT logoSRPTSarepta Therapeutics, Inc.
$20.81$2.2B-2.9215.58%-6.93%-9.96%—
CRSP logoCRSPCRISPR Therapeutics AG
$59.03$5.69B-9.12-89.97%-3368.72%-24.39%—
BMRN logoBMRNBioMarin Pharmaceutical Inc.
$63.37$12.25B35.2112.87%2.14%1.18%—
FOLD logoFOLDAmicus Therapeutics, Inc.
$14.49$4.55B-164.8520.05%-4.27%-12.02%—
RARE logoRAREUltragenyx Pharmaceutical Inc.
$15.62$1.54B-2.6820.13%-81.79%——

Compare DYN vs Peers

Dyne Therapeutics, Inc. (DYN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs SRPT

Most directly comparable listed peer for DYN.

Scale Benchmark

vs LLY

Larger-name benchmark to compare DYN against a more recognizable public peer.

Peer Set

Compare Top 5

vs SRPT, CRSP, BMRN, FOLD

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

DYN SEC Filings & Documents

Dyne Therapeutics, Inc. (DYN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jul 29, 2026·SEC

Material company update

Jul 22, 2026·SEC

Material company update

Jul 20, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 2, 2026·SEC

FY 2025

Feb 27, 2025·SEC

10-Q Quarterly Reports

6
FY 2026

Jul 29, 2026·SEC

FY 2026

May 11, 2026·SEC

FY 2025

Nov 5, 2025·SEC

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DYN Frequently Asked Questions

Dyne Therapeutics, Inc. (DYN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is DYN profitable?

Dyne Therapeutics, Inc. (DYN) reported a net loss of $519.4M for fiscal year 2025.

Dividend & Returns
What is DYN's return on equity?

Dyne Therapeutics, Inc. (DYN) has a return on equity (ROE) of -55.7%. Negative ROE indicates the company is unprofitable.

What is Dyne Therapeutics, Inc.'s free cash flow?

Dyne Therapeutics, Inc. (DYN) had negative free cash flow of $499.2M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in DYN back in 2007?

Total return calculator · dividends reinvested · 19+ years of data

See returns →