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EWTXEdgewise Therapeutics, Inc.
$39.23$4.2B
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EWTX logo

Edgewise Therapeutics, Inc.

EWTX
NASDAQ · Biotechnology
$39.23
At close - Oct 8, 4:00 PM EDT - USD
Market Cap$4.22B
P/E-24.1x
52W High$48.50
Volume1.36M
OverviewTerminalAnalysisFinancialsValuationEarningsBreakoutsOwnership
VCP Research Verdict2026Q2

Pre-Revenue Burn Escalation Masks Pivotal Trial Potential

Edgewise Therapeutics is a pre-revenue biotech advancing sevasemten for muscular dystrophies, with the GRAND CANYON pivotal trial in Becker muscular dystrophy representing a key value inflection. However, the company's cash runway appears critically short, wit...

GrowthDecelerating
ProfitabilityNegative
ValuationReview
TechnicalsMixed
Explore valuation models
MARKET ACTION

EWTX price & volume

Price trend, volume and key moving averages

Launch Terminal
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Decision Checklist4 Core Signals

What matters now

The signals most likely to change the investment case.

01

Earnings momentum

7/12 Beats

EPS beat 7 of last 12 quarters

02

Valuation risk

-223% Peers

P/E is 223% below peer median

03

Market leadership

RS 85 · Leader

High momentum (Outperforming 85% of market)

04

Mixed Trend

Mixed

Price < 50DMA but > 200DMA

Next CatalystEstimated earnings · Nov 6

Market performance

Price History →

Trailing total returns as of 10/10/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC).

YTD Return
EWTX+65.18%
S&P 500 (^GSPC)+13.29%
1-Year Return
EWTX+155.57%
S&P 500 (^GSPC)+14.98%
3-Year Return
EWTX+482.91%
S&P 500 (^GSPC)+87.27%
5-Year Return
EWTX+114.37%
S&P 500 (^GSPC)+71.33%

Growth & profitability

Annual revenue & EPS trend
Revenue
-
Net income
-$168M-25.4% YoY
Free cash flow
-$144M-30.3% YoY
Operating margin
-
ROIC (TTM)-32.4%
Avg ROIC 5Y-
ROE (TTM)-34.2%
Piotroski Score3 / 9
Financial Statements →
03

Monitor what changed

Recent results and news deserve attention only when they alter the forward view.

OPERATING RESULTS

Recent Earnings

Earnings History
EPS Beat Rate7/12 (58%)
QuarterEPS (Act vs Est)Revenue (Act vs Est)
Q3 2026Latest
Aug 6, 2026
-$0.53-13.3%
vs -$0.47
—
vs —
Q2 2026
May 7, 2026
-$0.46+8.0%
vs -$0.50
—
vs —
Q1 2026
Feb 26, 2026
-$0.47-9.3%
vs -$0.43
—
vs —
Q4 2025
Nov 6, 2025
-$0.39+2.5%
vs -$0.40
—
vs —
Historical baseline: 12 quarters analyzedGAAP / Adjusted
MARKET COVERAGE

Latest News

5 Stories
Seeking Alpha·Sep 22, 2026
Edgewise Therapeutics, Inc. (EWTX) Discusses Differentiated Mechanism of Action of Cardiac Sarcomere Modulator EDG-7500 Transcript

Edgewise Therapeutics, Inc. (EWTX) Discusses Differentiated Mechanism of Action of Cardiac Sarcomere Modulator EDG-7500 Transcript

PRNewsWire·Sep 22, 2026
Edgewise Therapeutics Unveils the Differentiated Mechanism of Action (MoA) of its Cardiac Sarcomere Modulator EDG-7500

- The MoA that targets the Regulatory Light Chain (RLC) has shown in preclinical models to improve cardiac relaxation while preserving systolic function and cardiac reserve - - Company to host webcast to discuss these findings today at 8:30 a.m. Eastern Time - BOULDER, Colo.

Schaeffers Research·Sep 18, 2026
Biotech Options Buzz: UTHR, NMRA, EWTX

Biotech stocks are dominating today's unusual options volume list, with United Therapeutics Corporation (NASDAQ: UTHR), Neumora Therapeutics Inc (NASDAQ: NMRA), and Edgewise Therapeutics Inc (NASDAQ: EWTX) all attracting outsized attention in the options pits.

Defense World·Sep 11, 2026
91,638 Shares in Edgewise Therapeutics, Inc. $EWTX Acquired by Hsbc Holdings PLC

Hsbc Holdings PLC purchased a new position in shares of Edgewise Therapeutics, Inc. (NASDAQ: EWTX) in the second quarter, according to the company in its most recent filing with the Securities and Exchange Commission. The institutional investor purchased 91,638 shares of the company's stock, valued at approximately $3,723,000. Hsbc Holdings PLC owned 0.08%

Filtered for Edgewise Therapeutics, Inc.More Headlines
04

Compare before deciding

Benchmark EWTX against direct peers instead of judging its metrics in isolation.

Peers Comparison

Key metrics vs top competitors for Edgewise Therapeutics, Inc. (EWTX)

Full Screener →
CompanyPriceMarket CapP/E RatioRev Growth (1Y)Net MarginROEDiv Yield
EWTX logoEWTXEdgewise Therapeutics, Inc.Current
$39.23$4.22B-24.07——-34.19%—
ACAD logoACADACADIA Pharmaceuticals Inc.
$19.58$3.35B8.5511.87%33.42%32.39%—
KYMR logoKYMRKymera Therapeutics, Inc.
$109.30$8.99B-29.62-16.72%-285.41%-21.5%—
CMPS logoCMPSCOMPASS Pathways plc
$11.47$1.55B-3.72——-398.21%—
IMVT logoIMVTImmunovant, Inc.
$30.26$6.25B-10.92—-7585.86%-69.59%—
ARQT logoARQTArcutis Biotherapeutics, Inc.
$24.49$3.06B-188.3891.34%6.15%15.05%—

Compare EWTX vs Peers

Edgewise Therapeutics, Inc. (EWTX) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for EWTX.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare EWTX against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, KYMR, CMPS, IMVT

05

Keep researching

Verify the primary filings, follow material updates, and answer the remaining questions.

EWTX SEC Filings & Documents

Edgewise Therapeutics, Inc. (EWTX) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Aug 6, 2026·SEC

Material company update

Jul 13, 2026·SEC

Material company update

Jun 5, 2026·SEC

10-K Annual Reports

3
FY 2026

Feb 26, 2026·SEC

FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 22, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

Aug 6, 2026·SEC

FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

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EWTX Frequently Asked Questions

Edgewise Therapeutics, Inc. (EWTX) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials
Is EWTX profitable?

Edgewise Therapeutics, Inc. (EWTX) reported a net loss of $197.2M for fiscal year 2025.

Dividend & Returns
What is EWTX's return on equity?

Edgewise Therapeutics, Inc. (EWTX) has a return on equity (ROE) of -34.2%. Negative ROE indicates the company is unprofitable.

What is Edgewise Therapeutics, Inc.'s free cash flow?

Edgewise Therapeutics, Inc. (EWTX) had negative free cash flow of $159.6M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in EWTX back in 2019?

Total return calculator · dividends reinvested · 7+ years of data

See returns →