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ITRMIterum Therapeutics plc
$0.03$2M
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ITRM logoIterum Therapeutics plc(ITRM)Earnings, Financials & Key Ratios

ITRM•NASDAQ
Price updated May 31, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryVaccines and Infectious Disease
AboutIterum Therapeutics plc, a clinical-stage pharmaceutical company, engages in developing and commercializing anti-infectives in Ireland, Bermuda, and the United States. It is developing sulopenem, a novel anti-infective compound with oral and IV formulations that is in Phase III clinical trials for the treatment of uncomplicated urinary tract infections, complicated urinary tract infections, and complicated intra-abdominal infections. The company was incorporated in 2015 and is headquartered in Dublin, Ireland.Show more
  • Revenue$0
  • EBITDA-$18M+59.7%
  • Net Income-$25M+35.4%
  • EPS (Diluted)-1.26+57.4%

ITRM Key Insights

Iterum Therapeutics plc (ITRM) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Strong 5Y profit CAGR of 24.8%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Weak momentum: RS Rating 0 (bottom 0%)
  • ✗Shares diluted 52.0% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ITRM Price & Volume

Iterum Therapeutics plc (ITRM) stock price & volume — 10-year historical chart

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ITRM Growth Metrics

Iterum Therapeutics plc (ITRM) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM11.76%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM62.5%

Return on Capital

10 Years-111.69%
5 Years-85.94%
3 Years-91.11%
Last Year-94.11%

ITRM Peer Comparison

Iterum Therapeutics plc (ITRM) competitors in Vaccines and Infectious Disease — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor8.15B282.31-20.94-100%-43.02%0.00
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
SPRO logoSPROSpero Therapeutics, Inc.Direct Competitor132.02M2.2815.2024.27%27.82%35.58%0.05
VNDA logoVNDAVanda Pharmaceuticals Inc.Direct Competitor342.83M5.80-1.558.72%-109.99%-61.41%0.04
CMPX logoCMPXCompass Therapeutics, Inc.Product Competitor279.34M2.02-4.81-100%-39.75%0.05
MTNB logoMTNBMatinas BioPharma Holdings, Inc.Product Competitor3.56M0.60-0.12-100%-270.65%0.38
AGEN logoAGENAgenus Inc.Product Competitor124.93M3.00-882.3510.37%52.16%
TARS logoTARSTarsus Pharmaceuticals, Inc.Product Competitor2.72B63.16-39.72146.71%-9.02%-14.19%0.27

Compare ITRM vs Peers

Iterum Therapeutics plc (ITRM) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRAX

Most directly comparable listed peer for ITRM.

Scale Benchmark

vs IQV

Larger-name benchmark to compare ITRM against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRAX, NKTR, SPRO, VNDA

ITRM Income Statement

Iterum Therapeutics plc (ITRM) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue
0508K869K37K00000390K
Revenue Growth %
--71.06%-95.74%-100%-----
Cost of Goods Sold
0000161K2.1M1.8M1.75M254K1.06M
COGS % of Revenue
----------
Gross Profit
0▲ 0%
508K▲ 0%
869K▲ 71.1%
37K▼ 95.7%
-161K▼ 535.1%
-2.1M▼ 1206.8%
-1.8M▲ 14.4%
-1.75M▲ 2.8%
-254K▲ 85.5%
-668K▲ 0%
Gross Margin %
-100%100%100%------171.28%
Gross Profit Growth %
--71.06%-95.74%-535.14%-1206.83%14.45%2.78%85.49%-
Operating Expenses
13.36M29.96M77.43M102.06M31.96M22.43M28.58M45.72M18.44M19.62M
OpEx % of Revenue
-5898.23%8910.01%275832.43%------
Selling, General & Admin
3.26M4.46M8.78M11.28M11.05M13.82M12.77M7.48M7.98M15.57M
SG&A % of Revenue
-878.74%1010.47%30497.3%------
Research & Development
10.1M25.5M68.65M90.77M20.91M8.61M15.82M38.24M10.46M3.8M
R&D % of Revenue
-5019.49%7899.54%245335.14%------
Other Operating Expenses
8K0401K196K00000254K
Operating Income
-13.36M▲ 0%
-29.45M▼ 120.5%
-76.56M▼ 159.9%
-102.02M▼ 33.3%
-32.13M▲ 68.5%
-24.54M▲ 23.6%
-30.38M▼ 23.8%
-47.47M▼ 56.2%
-18.7M▲ 60.6%
-20.29M▲ 0%
Operating Margin %
--5798.23%-8810.01%-275732.43%------5202.82%
Operating Income Growth %
--120.49%-159.92%-33.26%68.51%23.62%-23.83%-56.23%60.61%-
EBITDA
0-29.39M-76.42M-101.87M-31.96M-22.43M-28.58M-45.72M-18.41M-18.98M
EBITDA Margin %
--5785.43%-8794.36%-275321.62%------4865.38%
EBITDA Growth %
---160.03%-33.3%68.62%29.82%-27.41%-59.95%59.73%27%
D&A (Non-Cash Add-back)
13.36M65K136K152K161K2.1M1.8M1.75M284K1.32M
EBIT
-13.35M-29.45M-76.16M-101.83M-36.17M-85.31M-41.77M-36.33M-22.01M-24.39M
Net Interest Income
0277K-426K-861K-15.09M-5.55M-2.36M1.43M0-2.17M
Interest Income
0277K0012.3K4.53K2.36K1.43M0133K
Interest Expense
00426K861K15.1M5.55M2.36M002.3M
Other Income/Expense
8K493K-25K-665K-19.14M-66.32M-13.75M9.71M-5.84M-6.39M
Pretax Income
-13.35M▲ 0%
-28.96M▼ 116.9%
-76.58M▼ 164.4%
-102.69M▼ 34.1%
-51.26M▲ 50.1%
-90.86M▼ 77.2%
-44.13M▲ 51.4%
-37.76M▲ 14.4%
-24.53M▲ 35.0%
-26.68M▲ 0%
Pretax Margin %
--5701.18%-8812.89%-277529.73%------6842.31%
Income Tax
113K444K472K444K743K705K301K613K240K276K
Effective Tax Rate %
-0.85%-1.53%-0.62%-0.43%-1.45%-0.78%-0.68%-1.62%-0.98%-1.03%
Net Income
-13.46M▲ 0%
-29.41M▼ 118.4%
-77.06M▼ 162.0%
-103.13M▼ 33.8%
-52.01M▲ 49.6%
-91.56M▼ 76.1%
-44.43M▲ 51.5%
-38.37M▲ 13.6%
-24.77M▲ 35.4%
-26.96M▲ 0%
Net Margin %
--5788.58%-8867.2%-278729.73%------6913.08%
Net Income Growth %
--118.4%-162.04%-33.84%49.57%-76.06%51.47%13.64%35.44%11.76%
Net Income (Continuing)
-13.46M-29.41M-77.06M-103.13M-52.01M-91.56M-44.43M-38.37M-24.77M-26.96M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-26.59▲ 0%
-58.08▼ 118.4%
-98.32▼ 69.3%
-7.10▲ 92.8%
-32.49▼ 357.6%
-8.41▲ 74.1%
-3.63▲ 56.8%
-2.96▲ 18.5%
-1.26▲ 57.4%
-0.59▲ 0%
EPS Growth %
--118.43%-69.28%92.78%-357.61%74.12%56.84%18.46%57.43%62.5%
EPS (Basic)
-26.59-58.08-98.32-7.10-32.49-8.41-3.63-2.96-1.26-
Diluted Shares Outstanding
13.96M549.15K631.57K1.05M24.01M10.89M12.24M12.96M19.7M45.8M
Basic Shares Outstanding
13.96M549.15K631.57K1.05M24.01M10.89M12.24M12.96M19.7M45.8M
Dividend Payout Ratio
----------

ITRM Balance Sheet

Iterum Therapeutics plc (ITRM) balance sheet — assets, liabilities & shareholders' equity

MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets
25.86M44.17M84.67M9.38M21.47M83.27M62.44M25.6M24.79M13.73M
Cash & Short-Term Investments
24.81M39.22M84.67M4.83M14.57M81.34M60.8M23.93M24.13M11M
Cash Only
24.81M8.48M44.55M4.83M14.57M27.45M21.09M6.07M24.13M11M
Short-Term Investments
030.73M40M0053.9M39.71M17.86M00
Accounts Receivable
245K509K721K1.11M865K1.21M513K233K66K546K
Days Sales Outstanding
-365.72302.8410.96K-----166.36
Inventory
00-7.87M0000001.15M
Days Inventory Outstanding
---------226.83
Other Current Assets
0180K959K1.14M5.24M37K35K065K0
Total Non-Current Assets
1.05M2.58M13.2M16.37M11.32M8.24M4.39M663K19.81M18.78M
Property, Plant & Equipment
0747K700K7.72M5.68M3.83M1.84M600K23K18K
Fixed Asset Turnover
-0.68x1.24x0.00x-----21.97x
Goodwill
0000000000
Intangible Assets
000003.44M1.72M019.75M18.71M
Long-Term Investments
00959K60K248K64K34K0063K
Other Non-Current Assets
1.05M1.84M11.54M8.6M5.39M912K797K63K39K19K
Total Assets
26.92M▲ 0%
46.76M▲ 73.7%
97.87M▲ 109.3%
25.75M▼ 73.7%
32.79M▲ 27.3%
91.51M▲ 179.1%
66.83M▼ 27.0%
26.26M▼ 60.7%
44.59M▲ 69.8%
32.5M▲ 0%
Asset Turnover
-0.01x0.01x0.00x-----0.01x
Asset Growth %
-73.71%109.32%-73.69%27.34%179.06%-26.97%-60.71%69.83%381.94%
Total Current Liabilities
4.22M7.13M12.22M36.99M41.7M12.94M9.06M13.52M17.61M6.43M
Accounts Payable
1.48M3.15M4.04M15.49M816K878K2.77M5M251K577K
Days Payables Outstanding
----1.85K152.31562.511.04K360.69209.58
Short-Term Debt
001.02M6.38M7.06M2.09M332K014.46M281K
Deferred Revenue (Current)
00113K0000000
Other Current Liabilities
1.95M2.92M5.24M13.71M32.75M8.98M3.99M761K240K4.67M
Current Ratio
6.13x6.20x6.93x0.25x0.51x6.43x6.89x1.89x1.41x2.13x
Quick Ratio
6.13x6.20x7.57x0.25x0.51x6.43x6.89x1.89x1.41x1.96x
Cash Conversion Cycle
---------183.61
Total Non-Current Liabilities
30K137K26.25M15M41.65M28.33M29.77M19.14M31.07M33.45M
Long-Term Debt
0013.08M7.63M35.85M24.9M28.47M18.96M31.07M33.45M
Capital Lease Obligations
0006.75M5.17M3.44M1.3M000
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
30K137K951K630K630K00188K00
Total Liabilities
4.25M7.26M26.25M51.99M83.35M41.27M38.83M32.66M48.68M39.88M
Total Debt
0013.08M20.75M48.08M30.43M30.1M18.96M45.53M33.73M
Net Debt
-24.81M-8.48M-31.47M15.92M33.52M2.98M9.01M12.88M21.41M22.73M
Debt / Equity
--0.18x--0.61x1.08x---4.57x
Debt / EBITDA
----------1.78x
Net Debt / EBITDA
----------1.20x
Interest Coverage
---178.77x-118.26x-2.40x-15.36x-17.69x---10.61x
Total Equity
22.67M▲ 0%
39.49M▲ 74.2%
71.62M▲ 81.3%
-26.24M▼ 136.6%
-50.56M▼ 92.7%
50.23M▲ 199.4%
28M▼ 44.3%
-6.4M▼ 122.9%
-4.08M▲ 36.3%
-7.38M▲ 0%
Equity Growth %
-74.23%81.35%-136.63%-92.69%199.36%-44.26%-122.87%36.26%194.97%
Book Value per Share
1.6271.92113.40-24.99-2.114.612.29-0.49-0.21-0.16
Total Shareholders' Equity
22.67M39.49M71.62M-26.24M-50.56M50.23M28M-6.4M-4.08M-7.38M
Common Stock
4K4K144K149K494K1.83M126K135K315K490K
Retained Earnings
-25.33M-54.74M-131.79M-234.92M-286.93M-378.49M-422.93M-461.3M-486.07M-506.45M
Treasury Stock
0000000000
Accumulated OCI
0-65K-201K000-350K1K00
Minority Interest
0000000000

ITRM Cash Flow Statement

Iterum Therapeutics plc (ITRM) cash flow — operating, investing & free cash flow history

MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations
-11.3M-30.6M-75.89M-81.92M-54.53M-15.84M-18.47M-39.33M-26.77M-19.91M
Operating CF Margin %
--6024.41%-8733.03%-221410.81%------
Operating CF Growth %
--170.88%-147.97%-7.95%33.44%70.95%-16.61%-112.91%31.93%-20.52%
Net Income
-13.46M-29.41M-77.06M-103.13M-52.01M-91.56M-44.43M-38.37M-24.77M-26.96M
Depreciation & Amortization
065K136K152K161K2.1M1.8M1.75M284K1.32M
Stock-Based Compensation
348K392K1.29M2.17M2.76M4.32M22.11M784K363K206K
Deferred Taxes
044K-701K01.41M61.6M0000
Other Non-Cash Items
-830K-95K2.04M984K17.71M8.14M-258K-6.26M10.09M8.42M
Working Capital Changes
1.82M-1.6M-1.6M17.9M-24.56M-440K2.31M2.76M-12.73M-2.9M
Change in Receivables
0000000000
Change in Inventory
000000000-1.17M
Change in Payables
1.19M1.67M849K11.45M-14.67M63K1.9M2.22M-4.75M-279.19K
Cash from Investing
0-31.59M-8.66M40.1M-11K-54.59M13.96M23.34M18.21M1.09M
Capital Expenditures
0-812K-90K-24K-11K-61K-62K-13K-2K-14.57K
CapEx % of Revenue
-159.84%10.36%64.86%-----3.73%
Acquisitions
0000054.53K0000
Investments
----------
Other Investing
0-30.77K-8.57K00-54.53K0000
Cash from Financing
20.85M45.87M120.84M2.06M64.47M83.13M-1.82M1.03M26.69M16.27M
Debt Issued (Net)
0014.51M-1.03M-5.49M-6.52M-2.25M00-109.46K
Equity Issued (Net)
20.85M45.87M106.33M3.04M69.96M89.64M433K1.03M26.69M31.12M
Dividends Paid
0000000000
Share Repurchases
0000000000
Other Financing
00060K00000-14.74M
Net Change in Cash
9.55M▲ 0%
-16.32M▼ 270.9%
36.19M▲ 321.7%
-39.78M▼ 209.9%
9.93M▲ 124.9%
12.69M▲ 27.9%
-6.38M▼ 150.3%
-15.02M▼ 135.3%
18.05M▲ 220.2%
-2.4M▲ 0%
Free Cash Flow
-11.3M▲ 0%
-31.42M▼ 178.1%
-75.98M▼ 141.9%
-81.95M▼ 7.9%
-54.54M▲ 33.4%
-15.9M▲ 70.8%
-18.54M▼ 16.6%
-39.34M▼ 112.3%
-26.77M▲ 32.0%
-19.93M▲ 0%
FCF Margin %
--6184.25%-8743.38%-221475.68%------5110.05%
FCF Growth %
--178.07%-141.85%-7.85%33.45%70.84%-16.55%-112.26%31.95%43.64%
FCF per Share
-0.81-57.21-120.30-78.04-2.27-1.46-1.51-3.04-1.36-0.44
FCF Conversion (FCF/Net Income)
0.84x1.04x0.98x0.79x1.05x0.17x0.42x1.02x1.08x0.74x
Interest Paid
00809K1.4M996K416K22K000
Taxes Paid
130K439K352K414K120K435K821K401K220K81K

ITRM Key Ratios

Iterum Therapeutics plc (ITRM) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric20172018201920202021202220232024TTM
Return on Equity (ROE)
-94.61%-138.69%-454.48%--182.28%-113.59%-355.35%-602.38%
Return on Invested Capital (ROIC)
-153.05%-161.38%-512.94%--101.76%-50.51%-163.72%-117.78%-93.44%
Gross Margin
100%100%100%------171.28%
Net Margin
-5788.58%-8867.2%-278729.73%------6913.08%
Debt / Equity
-0.18x--0.61x1.08x---4.57x
Interest Coverage
--178.77x-118.26x-2.40x-15.36x-17.69x---10.61x
FCF Conversion
1.04x0.98x0.79x1.05x0.17x0.42x1.02x1.08x0.74x
Revenue Growth
-71.06%-95.74%-100%-----
Related:ITRM Dividend History·ITRM Revenue History·ITRM Price History·ITRM P/E History·ITRM Financial Ratios·ITRM Institutional Holders

ITRM SEC Filings & Documents

Iterum Therapeutics plc (ITRM) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Mar 31, 2026·SEC

Material company update

Mar 27, 2026·SEC

Material company update

Mar 3, 2026·SEC

10-K Annual Reports

2
FY 2025

Feb 7, 2025·SEC

FY 2024

Mar 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 14, 2025·SEC

FY 2025

Aug 5, 2025·SEC

FY 2025

May 13, 2025·SEC

ITRM Frequently Asked Questions

Iterum Therapeutics plc (ITRM) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Iterum Therapeutics plc (ITRM) reported $0.4M in revenue for fiscal year 2024.

Iterum Therapeutics plc (ITRM) grew revenue by 0.0% over the past year. Growth has been modest.

Iterum Therapeutics plc (ITRM) reported a net loss of $27.0M for fiscal year 2024.

Dividend & Returns

Iterum Therapeutics plc (ITRM) had negative free cash flow of $19.9M in fiscal year 2024, likely due to heavy capital investments.

What if you invested $1,000 in ITRM back in 2016?

Total return calculator · dividends reinvested · 10+ years of data

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