| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| KRYSKrystal Biotech, Inc. | 8.18B | 282.01 | 94.00 | 473.02% | 53.3% | 17.48% | 1.46% | 0.01 |
| BMRNBioMarin Pharmaceutical Inc. | 10.58B | 55.07 | 24.92 | 17.97% | 16.82% | 8.59% | 4.49% | 0.11 |
| SRPTSarepta Therapeutics, Inc. | 2.23B | 21.31 | 9.11 | 52.97% | -11.25% | -20.57% | 0.88 | |
| RAREUltragenyx Pharmaceutical Inc. | 2.27B | 23.50 | -3.74 | 29.01% | -91.95% | -35.88% | 0.15 | |
| DYNDyne Therapeutics, Inc. | 2.7B | 16.42 | -4.87 | -61.26% | 0.04 | |||
| TVTXTravere Therapeutics, Inc. | 2.54B | 28.40 | -6.96 | 60.55% | -20.32% | -120.36% | 6.80 | |
| BEAMBeam Therapeutics Inc. | 3.25B | 32.05 | -7.00 | -83.18% | -7.44% | -42.92% | 0.22 | |
| SLNOSoleno Therapeutics, Inc. | 2.25B | 41.95 | -9.58 | -79.5% | -15.85% | 0.22 |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 0 | 13.29M | 15.56M | 37.7M | 15.92M | 14.02M | 33.28M |
| Revenue Growth % | - | - | - | - | 0.17% | 1.42% | -0.58% | -0.12% | 1.37% |
| Cost of Goods Sold | 243.08K | 679.18K | 2.05M | 0 | 0 | 0 | 0 | 0 | 23.79M |
| COGS % of Revenue | - | - | - | - | - | - | - | - | 0.71% |
| Gross Profit | -243.08K | -679.18K | -2.05M | 13.29M | 15.56M | 37.7M | 15.92M | 14.02M | 9.49M |
| Gross Margin % | - | - | - | 1% | 1% | 1% | 1% | 1% | 0.29% |
| Gross Profit Growth % | - | -1.79% | -2.02% | 7.47% | 0.17% | 1.42% | -0.58% | -0.12% | -0.32% |
| Operating Expenses | 20.06M | 31.68M | 78.1M | 71.56M | 78.12M | 110.46M | 132.28M | 151.08M | 173.7M |
| OpEx % of Revenue | - | - | - | 5.38% | 5.02% | 2.93% | 8.31% | 10.78% | 5.22% |
| Selling, General & Admin | 6.03M | 9.33M | 44.48M | 46.68M | 44.21M | 43.77M | 46.55M | 47.29M | 54.22M |
| SG&A % of Revenue | - | - | - | 3.51% | 2.84% | 1.16% | 2.92% | 3.37% | 1.63% |
| Research & Development | 14.04M | 22.36M | 33.62M | 24.88M | 33.91M | 66.69M | 85.72M | 103.78M | 119.48M |
| R&D % of Revenue | - | - | - | 1.87% | 2.18% | 1.77% | 5.38% | 7.4% | 3.59% |
| Other Operating Expenses | 0 | -553.5K | 83.08K | 0 | 0 | 0 | 0 | 0 | 0 |
| Operating Income | -20.06M | -31.68M | -78.1M | -58.27M | -62.55M | -72.76M | -116.36M | -137.06M | -164.21M |
| Operating Margin % | - | - | - | -4.38% | -4.02% | -1.93% | -7.31% | -9.78% | -4.93% |
| Operating Income Growth % | - | -0.58% | -1.47% | 0.25% | -0.07% | -0.16% | -0.6% | -0.18% | -0.2% |
| EBITDA | -19.82M | -31.01M | -76.05M | -56.03M | -58.38M | -64.89M | -107.75M | -123.33M | -151.38M |
| EBITDA Margin % | - | - | - | -4.22% | -3.75% | -1.72% | -6.77% | -8.8% | -4.55% |
| EBITDA Growth % | - | -0.56% | -1.45% | 0.26% | -0.04% | -0.11% | -0.66% | -0.14% | -0.23% |
| D&A (Non-Cash Add-back) | 243.08K | 679.18K | 2.05M | 2.24M | 4.17M | 7.87M | 8.6M | 13.73M | 12.83M |
| EBIT | -20.06M | -31.68M | -78.1M | -54.7M | -57.85M | -79.27M | -124.67M | -70.78M | -134.52M |
| Net Interest Income | 6.63K | -16.79K | 19.98K | 321.99K | 1.14M | -76K | -4.17M | -10.97M | -9.13M |
| Interest Income | 32.07K | 26.07K | 53.41K | 370.6K | 1.28M | 212K | 777K | 2.27M | 4.14M |
| Interest Expense | 25.44K | 42.86K | 33.43K | 48.61K | 139.2K | 288K | 4.95M | 13.24M | 13.27M |
| Other Income/Expense | 272.17K | 640.19K | -5.24M | 3.52M | 4.56M | -6.8M | -13.26M | 53.03M | 16.42M |
| Pretax Income | -19.79M | -31.04M | -83.34M | -54.75M | -57.99M | -79.56M | -129.62M | -84.03M | -147.79M |
| Pretax Margin % | - | - | - | -4.12% | -3.73% | -2.11% | -8.14% | -5.99% | -4.44% |
| Income Tax | 0 | 0 | -474.39K | 0 | 0 | 0 | 0 | 0 | 0 |
| Effective Tax Rate % | 0.98% | 1% | 0.99% | 1% | 1% | 1% | 1% | 1% | 1% |
| Net Income | -19.49M | -31.04M | -82.87M | -54.75M | -57.99M | -79.56M | -129.62M | -84.03M | -147.79M |
| Net Margin % | - | - | - | -4.12% | -3.73% | -2.11% | -8.14% | -5.99% | -4.44% |
| Net Income Growth % | - | -0.59% | -1.67% | 0.34% | -0.06% | -0.37% | -0.63% | 0.35% | -0.76% |
| Net Income (Continuing) | -19.79M | -31.04M | -82.87M | -54.75M | -57.99M | -79.56M | -129.62M | -84.03M | -147.79M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -1.01 | -3.62 | -4.37 | -1.58 | -1.43 | -1.63 | -3.16 | -1.49 | -2.12 |
| EPS Growth % | - | -2.58% | -0.21% | 0.64% | 0.09% | -0.14% | -0.94% | 0.53% | -0.42% |
| EPS (Basic) | -1.01 | -3.62 | -4.37 | -1.58 | -1.43 | -1.63 | -3.16 | -1.49 | -2.12 |
| Diluted Shares Outstanding | 19.24M | 8.57M | 18.95M | 33.16M | 37.72M | 44.14M | 45.18M | 56.49M | 69.82M |
| Basic Shares Outstanding | 19.24M | 8.57M | 18.95M | 33.16M | 37.72M | 44.14M | 45.18M | 56.49M | 69.82M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 19.09M | 11.48M | 74.65M | 268.98M | 272.58M | 183.24M | 154.34M | 159.62M | 123.52M |
| Cash & Short-Term Investments | 17.48M | 8.55M | 68.08M | 227.23M | 209.52M | 137.7M | 115.52M | 129.57M | 103.66M |
| Cash Only | 17.48M | 8.55M | 68.08M | 227.23M | 209.52M | 137.7M | 115.52M | 129.57M | 103.66M |
| Short-Term Investments | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accounts Receivable | 0 | 0 | 0 | 37.11M | 55.41M | 35.02M | 29.02M | 23.41M | 10.63M |
| Days Sales Outstanding | - | - | - | 1.02K | 1.3K | 339.02 | 665.41 | 609.72 | 116.57 |
| Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 385K |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | 5.91 |
| Other Current Assets | 400.96K | 965.23K | 4.63M | 170.59K | 564.44K | 2.42M | 1.67M | 1.02M | 2.02M |
| Total Non-Current Assets | 3.46M | 14.38M | 22.24M | 54.91M | 91.12M | 136.92M | 163.9M | 167.12M | 146.23M |
| Property, Plant & Equipment | 3.02M | 14.26M | 22.01M | 52.86M | 87.12M | 126.29M | 154.09M | 156.24M | 135.65M |
| Fixed Asset Turnover | - | - | - | 0.25x | 0.18x | 0.30x | 0.10x | 0.09x | 0.25x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 777.65K | 2.97M | 2.57M | 2.08M | 1.12M | 821K |
| Long-Term Investments | 444.84K | 123.38K | 123.38K | 123.38K | 0 | 6.66M | 6.33M | 6.77M | 6.75M |
| Other Non-Current Assets | 0 | 0 | 105.08K | 1.15M | 1.03M | 1.4M | 1.4M | 3M | 3.01M |
| Total Assets | 22.55M | 25.85M | 96.89M | 323.89M | 363.7M | 320.16M | 318.24M | 326.74M | 269.75M |
| Asset Turnover | - | - | - | 0.04x | 0.04x | 0.12x | 0.05x | 0.04x | 0.12x |
| Asset Growth % | - | 0.15% | 2.75% | 2.34% | 0.12% | -0.12% | -0.01% | 0.03% | -0.17% |
| Total Current Liabilities | 6.04M | 21.4M | 15.5M | 49.2M | 54.15M | 68.13M | 82.07M | 67.08M | 60.78M |
| Accounts Payable | 1.47M | 7.06M | 3.04M | 3.76M | 7.13M | 15.35M | 16.62M | 16.04M | 23.59M |
| Days Payables Outstanding | 2.21K | 3.79K | 541 | - | - | - | - | - | 361.85 |
| Short-Term Debt | 0 | 1.44M | 27.2K | 1.67M | 2.58M | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | -6.01K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K | 1000K |
| Other Current Liabilities | 1.96M | 2.68M | 6.14M | 11.23M | 17.09M | 6.03M | 16.23M | 41.28M | 12.1M |
| Current Ratio | 3.16x | 0.54x | 4.82x | 5.47x | 5.03x | 2.69x | 1.88x | 2.38x | 2.03x |
| Quick Ratio | 3.16x | 0.54x | 4.82x | 5.47x | 5.03x | 2.69x | 1.88x | 2.38x | 2.03x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | -239.38 |
| Total Non-Current Liabilities | 33.65M | 51.82M | 336.48K | 83.89M | 70.99M | 66.64M | 118.43M | 121.49M | 141.14M |
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 71.03M | 72.12M | 73.22M |
| Capital Lease Obligations | 5.46K | 34.3K | 7.1K | 21.5M | 19.67M | 20.36M | 17.33M | 12.95M | 7.52M |
| Deferred Tax Liabilities | -588.49K | -266.29K | -201.26K | 195.05K | 213.72K | 196K | 186K | 0 | 0 |
| Other Non-Current Liabilities | 33.64M | 51.78M | 329.38K | 1.65M | 1.81M | 3.03M | 2.44M | 2.4M | 2.82M |
| Total Liabilities | 39.69M | 73.22M | 15.84M | 133.09M | 125.14M | 134.76M | 200.5M | 188.57M | 201.92M |
| Total Debt | 11.47K | 1.51M | 34.3K | 23.18M | 22.25M | 23.73M | 92.25M | 89.26M | 84.8M |
| Net Debt | -17.47M | -7.04M | -68.05M | -204.05M | -187.27M | -113.97M | -23.27M | -40.3M | -18.86M |
| Debt / Equity | - | - | 0.00x | 0.12x | 0.09x | 0.13x | 0.78x | 0.65x | 1.25x |
| Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | - | - | - | - | - | - | - |
| Interest Coverage | -788.70x | -739.21x | -2336.42x | -1198.63x | -449.37x | -252.63x | -23.53x | -10.35x | -12.37x |
| Total Equity | -17.14M | -47.37M | 81.06M | 190.8M | 238.56M | 185.4M | 117.74M | 138.18M | 67.83M |
| Equity Growth % | - | -1.76% | 2.71% | 1.35% | 0.25% | -0.22% | -0.36% | 0.17% | -0.51% |
| Book Value per Share | -0.89 | -5.53 | 4.28 | 5.75 | 6.32 | 4.20 | 2.61 | 2.45 | 0.97 |
| Total Shareholders' Equity | -17.14M | -47.37M | 81.06M | 190.8M | 238.56M | 185.4M | 117.74M | 138.18M | 67.83M |
| Common Stock | 342 | 342 | 1.06K | 1.43K | 1.72K | 2K | 2K | 2K | 3K |
| Retained Earnings | -34.38M | -65.42M | -148.29M | -203.04M | -261.03M | -340.59M | -470.2M | -554.23M | -702.02M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -661.11K | -2.02M | 293.67K | -1.79M | -4.9M | -2.67M | 6.05M | -1.44M | -3.72M |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -14.37M | -18.06M | -58.89M | 20.04M | -63.97M | -10.53M | -73.1M | -105.36M | -104.5M |
| Operating CF Margin % | - | - | - | 1.51% | -4.11% | -0.28% | -4.59% | -7.52% | -3.14% |
| Operating CF Growth % | - | -0.26% | -2.26% | 1.34% | -4.19% | 0.84% | -5.94% | -0.44% | 0.01% |
| Net Income | -19.79M | -31.04M | -82.87M | -54.75M | -57.99M | -79.56M | -129.62M | -84.03M | -147.79M |
| Depreciation & Amortization | 243.08K | 679.18K | 2.05M | 2.24M | 4.17M | 7.87M | 8.6M | 13.72M | 12.68M |
| Stock-Based Compensation | 2.81M | 2.96M | 17.88M | 15.93M | 18.42M | 20.78M | 28.62M | 27.72M | 25.19M |
| Deferred Taxes | -261.82K | -1.21M | -474.39K | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 1.06M | 2.03M | 8.43M | -105.01K | 4.08M | 9.1M | 9.67M | -61.8M | -24.22M |
| Working Capital Changes | 1.58M | 8.53M | -3.92M | 56.73M | -32.64M | 31.28M | 9.62M | -983K | 29.64M |
| Change in Receivables | 0 | 0 | 0 | -32.29M | -16.12M | 16.7M | 5.17M | 4.83M | 9.43M |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -387K |
| Change in Payables | 453.13K | 4.73M | -2.12M | -8.68K | 1.57M | 13.35M | 3.74M | 2.33M | 10.74M |
| Cash from Investing | -2.59M | -10.54M | -11.26M | -9.37M | -37.02M | -61.72M | -44.96M | 34.03M | 23.48M |
| Capital Expenditures | -2.59M | -10.54M | -11.26M | -8.98M | -34.89M | -55.22M | -44.96M | -20.17M | -4.96M |
| CapEx % of Revenue | - | - | - | 0.68% | 2.24% | 1.46% | 2.82% | 1.44% | 0.15% |
| Acquisitions | - | - | - | - | - | - | - | - | - |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | 0 | 0 | 0 | 0 | -2.13M | 0 | 0 | 54.21M | 28.43M |
| Cash from Financing | 20.76M | 19.34M | 130.04M | 148.23M | 82.73M | 1.71M | 95.2M | 84.02M | 54.53M |
| Debt Issued (Net) | - | - | - | - | - | - | - | - | - |
| Equity Issued (Net) | - | - | - | - | - | - | - | - | - |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | - | - | - | - | - | - | - | - | - |
| Other Financing | 0 | 16.86M | 130.07M | -6.94M | -4.3M | 1.71M | -4.8M | -7.93M | -4.86M |
| Net Change in Cash | - | - | - | - | - | - | - | - | - |
| Free Cash Flow | -16.96M | -28.59M | -70.15M | 11.06M | -100.99M | -65.75M | -118.06M | -125.54M | -109.45M |
| FCF Margin % | - | - | - | 0.83% | -6.49% | -1.74% | -7.42% | -8.96% | -3.29% |
| FCF Growth % | - | -0.69% | -1.45% | 1.16% | -10.13% | 0.35% | -0.8% | -0.06% | 0.13% |
| FCF per Share | -0.88 | -3.34 | -3.70 | 0.33 | -2.68 | -1.49 | -2.61 | -2.22 | -1.57 |
| FCF Conversion (FCF/Net Income) | 0.74x | 0.58x | 0.71x | -0.37x | 1.10x | 0.13x | 0.56x | 1.25x | 0.71x |
| Interest Paid | 0 | 0 | 0 | 1.46K | 3K | 139K | 329K | 13.05M | 12.03M |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 |
|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | - | - | -491.87% | -40.28% | -27.01% | -37.53% | -85.52% | -65.67% | -143.48% |
| Return on Invested Capital (ROIC) | - | - | -450.13% | - | -246.7% | -88.93% | -105.2% | -106.89% | -167.75% |
| Gross Margin | - | - | - | 100% | 100% | 100% | 100% | 100% | 28.51% |
| Net Margin | - | - | - | -411.87% | -372.63% | -211.03% | -814.16% | -599.46% | -444.1% |
| Debt / Equity | - | - | 0.00x | 0.12x | 0.09x | 0.13x | 0.78x | 0.65x | 1.25x |
| Interest Coverage | -788.70x | -739.21x | -2336.42x | -1198.63x | -449.37x | -252.63x | -23.53x | -10.35x | -12.37x |
| FCF Conversion | 0.74x | 0.58x | 0.71x | -0.37x | 1.10x | 0.13x | 0.56x | 1.25x | 0.71x |
| Revenue Growth | - | - | - | - | 17.09% | 142.25% | -57.77% | -11.95% | 137.42% |
MeiraGTx Holdings plc (MGTX) reported $27.4M in revenue for fiscal year 2024.
MeiraGTx Holdings plc (MGTX) grew revenue by 137.4% over the past year. This is strong growth.
MeiraGTx Holdings plc (MGTX) reported a net loss of $168.7M for fiscal year 2024.
MeiraGTx Holdings plc (MGTX) has a return on equity (ROE) of -143.5%. Negative ROE indicates the company is unprofitable.
MeiraGTx Holdings plc (MGTX) had negative free cash flow of $121.0M in fiscal year 2024, likely due to heavy capital investments.