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Xenetic Biosciences, Inc. (XBIO) 10-Year Financial Performance & Capital Metrics

XBIO • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsHematologic Oncology
AboutXenetic Biosciences, Inc., a biopharmaceutical company, focuses on advancing XCART, a personalized chimeric antigen receptor T cell (CAR T) platform technology engineered to target patient-specific tumor neoantigens. The company engages in the discovery, research, and development of biologic drugs and oncology therapeutics. It advances cell-based therapeutics targeting the B-cell receptor on the surface of an individual patient's malignant tumor cells for the treatment of B-cell lymphomas. It is also leveraging PolyXen, its proprietary drug delivery platform, by partnering with biotechnology and pharmaceutical companies. It has collaboration agreements with Takeda Pharmaceutical Co. Ltd., Serum Institute of India Limited, PJSC Pharmsynthez, and SynBio LLC. Xenetic Biosciences, Inc. is headquartered in Framingham, Massachusetts.Show more
  • Revenue $3M -1.6%
  • EBITDA -$4M +10.3%
  • Net Income -$4M +4.2%
  • EPS (Diluted) -2.57 +5.2%
  • Gross Margin 100%
  • EBITDA Margin -162.03% +8.9%
  • Operating Margin -168.16% +5.4%
  • Net Margin -158.39% +2.7%
  • ROE -50.12% -42.1%
  • ROIC -964.01% -93.9%
  • Debt/Equity -
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 171.1%
  • ✓Trading at only 0.6x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Weak momentum: RS Rating 12 (bottom 12%)
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y171.13%
3Y29.15%
TTM13.3%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM22.59%

EPS CAGR

10Y-
5Y-
3Y-
TTM22.64%

ROCE

10Y Avg-81.91%
5Y Avg-51.46%
3Y Avg-44.56%
Latest-53.21%

Peer Comparison

Hematologic Oncology
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Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+03M7.58M017.07K436.94K1.16M1.71M2.54M2.5M
Revenue Growth %--1.53%-1%-24.6%1.66%0.47%0.49%-0.02%
Cost of Goods Sold+56.12K36.45K156.12K15.83K000000
COGS % of Revenue-0.01%0.02%-------
Gross Profit+-56.12K2.96M7.43M-15.83K17.07K436.94K1.16M1.71M2.54M2.5M
Gross Margin %-0.99%0.98%-1%1%1%1%1%1%
Gross Profit Growth %-53.81%1.51%-1%2.08%24.6%1.66%0.47%0.49%-0.02%
Operating Expenses+9.82M50.43M11M7.28M12.9M14.37M6.91M8.42M7.06M6.7M
OpEx % of Revenue-16.81%1.45%-756.12%32.9%5.95%4.94%2.78%2.68%
Selling, General & Admin6.39M6.69M6.94M4.39M4.73M3.4M3.74M3.65M3.56M3.42M
SG&A % of Revenue-2.23%0.91%-277.23%7.78%3.23%2.14%1.4%1.37%
Research & Development3.43M43.74M4.06M2.88M4.89M1.73M3.16M4.77M3.49M3.29M
R&D % of Revenue-14.58%0.54%-286.5%3.96%2.73%2.79%1.38%1.32%
Other Operating Expenses00-41.1K-24.64K3.28M9.24M0000
Operating Income+-9.82M-47.43M-3.57M-7.28M-12.89M-13.94M-5.75M-6.72M-4.52M-4.2M
Operating Margin %--15.81%-0.47%--755.12%-31.9%-4.95%-3.94%-1.78%-1.68%
Operating Income Growth %0.24%-3.83%0.92%-1.04%-0.77%-0.08%0.59%-0.17%0.33%0.07%
EBITDA+-9.77M-47.39M-3.54M-7.26M-12.86M-13.91M-5.71M-6.69M-4.52M-4.05M
EBITDA Margin %--15.8%-0.47%--753.51%-31.83%-4.92%-3.92%-1.78%-1.62%
EBITDA Growth %0.24%-3.85%0.93%-1.05%-0.77%-0.08%0.59%-0.17%0.33%0.1%
D&A (Non-Cash Add-back)56.12K36.45K23.78K15.83K27.49K28.84K35.48K27.04K0153.34K
EBIT-9.82M-53.48M-3.59M-7.28M-9.6M-4.69M-5.75M-6.72M-4.52M-4.2M
Net Interest Income+-265.31K-729.54K14.73K0108.49K126.17K100.47K167.15K355.76K249.86K
Interest Income1.69K3216.54K0108.49K126.17K100.47K167.15K355.76K249.86K
Interest Expense267K729.57K1.82K24.13K000000
Other Income/Expense-2.69M-6.78M-26.37K-24.13K111.8K125.68K101.59K165.56K381.14K244.15K
Pretax Income+-12.51M-54.21M-3.6M-7.3M-12.78M-13.81M-5.65M-6.55M-4.13M-3.96M
Pretax Margin %--18.07%-0.47%--748.57%-31.61%-4.86%-3.84%-1.63%-1.58%
Income Tax+0026.37K24.13K0-2.92M0000
Effective Tax Rate %1%1%1%1%1%0.79%1%1%1%1%
Net Income+-12.51M-54.21M-3.6M-7.3M-12.78M-10.89M-5.65M-6.55M-4.13M-3.96M
Net Margin %--18.07%-0.47%--748.57%-24.93%-4.86%-3.84%-1.63%-1.58%
Net Income Growth %0.13%-3.33%0.93%-1.03%-0.75%0.15%0.48%-0.16%0.37%0.04%
Net Income (Continuing)-12.51M-54.21M-3.6M-7.3M-12.78M-10.89M-5.65M-6.55M-4.13M-3.96M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-355.34-875.41-49.78-96.57-55.92-17.04-5.39-4.49-2.71-2.57
EPS Growth %0.15%-1.46%0.94%-0.94%0.42%0.7%0.68%0.17%0.4%0.05%
EPS (Basic)-355.34-875.41-49.78-96.58-55.92-17.04-5.39-4.49-2.71-2.57
Diluted Shares Outstanding35.2K61.92K72.21K75.6K285.25K639.24K1.03M1.42M1.53M1.54M
Basic Shares Outstanding35.2K61.92K72.21K75.59K285.25K639.24K1.03M1.42M1.53M1.54M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+4.19M8.34M5.88M1.19M11.09M12.37M18.72M13.65M9.59M6.59M
Cash & Short-Term Investments132.23K4.05M5.53M571.61K10.37M11.53M18.24M13.1M8.98M6.17M
Cash Only132.23K4.05M5.53M571.61K10.37M11.53M18.24M13.1M8.98M6.17M
Short-Term Investments0000000000
Accounts Receivable03M00000000
Days Sales Outstanding-365--------
Inventory0000000000
Days Inventory Outstanding----------
Other Current Assets66.51K66.51K99.51K66.51K527.08K0227.04K0603.83K0
Total Non-Current Assets+12.72M12.64M13.28M13.24M10.46M809.99K1.09M1.07M1.02M313.92K
Property, Plant & Equipment62.02K42.37K27.85K4.96K20.8K27.04K0000
Fixed Asset Turnover-70.81x272.39x-0.82x16.16x----
Goodwill3.28M3.28M3.28M3.28M000000
Intangible Assets9.24M9.24M9.24M9.24M9.24M00000
Long-Term Investments0000000000
Other Non-Current Assets129.31K66.34K724.71K705.66K1.19M782.94K1.09M1.07M1.02M313.92K
Total Assets+16.91M20.97M19.16M14.43M21.55M13.18M19.82M14.72M10.61M6.9M
Asset Turnover-0.14x0.40x-0.00x0.03x0.06x0.12x0.24x0.36x
Asset Growth %0.04%0.24%-0.09%-0.25%0.49%-0.39%0.5%-0.26%-0.28%-0.35%
Total Current Liabilities+7.34M1.87M1.94M1.6M1.42M936.93K1.42M1.07M809.59K894.26K
Accounts Payable1.79M1.01M786.78K934.15K931.13K327.4K362.47K287.36K240.83K283.62K
Days Payables Outstanding11.63K10.08K1.84K21.54K------
Short-Term Debt4.05M00020.04K00000
Deferred Revenue (Current)1000K000000000
Other Current Liabilities19.1K20.2K44.31K218.03K463.99K0039.95K48.26K34.2K
Current Ratio0.57x4.47x3.03x0.75x7.84x13.20x13.18x12.72x11.84x7.37x
Quick Ratio0.57x4.47x3.03x0.75x7.84x13.20x13.18x12.72x11.84x7.37x
Cash Conversion Cycle----------
Total Non-Current Liabilities+2.96M2.94M2.92M2.92M2.92M27.04K0000
Long-Term Debt0000000000
Capital Lease Obligations0000027.04K0000
Deferred Tax Liabilities2.92M2.92M2.92M2.92M2.92M00000
Other Non-Current Liabilities38.79K19.88K00000000
Total Liabilities10.3M4.8M4.86M4.52M4.33M963.97K1.42M1.07M809.59K894.26K
Total Debt+395K00020.04K62.52K27.04K000
Net Debt262.77K-4.05M-5.53M-571.61K-10.35M-11.47M-18.22M-13.1M-8.98M-6.17M
Debt / Equity0.06x---0.00x0.01x0.00x---
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage-36.79x-65.01x-1963.02x-301.53x------
Total Equity+6.61M16.17M14.3M9.91M17.21M12.22M18.39M13.65M9.8M6.01M
Equity Growth %-0.37%1.45%-0.12%-0.31%0.74%-0.29%0.51%-0.26%-0.28%-0.39%
Book Value per Share187.75261.13198.04131.1260.3519.1117.899.596.413.90
Total Shareholders' Equity6.61M16.17M14.3M9.91M17.21M12.22M18.39M13.65M9.8M6.01M
Common Stock162.01K8.73K9.04K9.73K6.09K8.77K13.46K1.52K1.54K1.54K
Retained Earnings-88.13M-142.34M-145.93M-153.23M-166.01M-176.9M-182.55M-189.1M-193.23M-197.19M
Treasury Stock-5.28M-5.28M-5.28M-5.28M-5.28M-5.28M-5.28M-5.28M-5.28M-5.28M
Accumulated OCI253.73K253.73K253.73K253.73K253.73K253.73K253.73K253.73K253.73K253.73K
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-5.3M-8.79M1.49M-6.46M-6.4M-4.27M-4.74M-4.65M-4.11M-2.82M
Operating CF Margin %--2.93%0.2%--374.98%-9.77%-4.08%-2.72%-1.62%-1.13%
Operating CF Growth %0.57%-0.66%1.17%-5.33%0.01%0.33%-0.11%0.02%0.11%0.32%
Net Income-12.51M-54.21M-3.6M-7.3M-12.78M-10.89M-5.65M-6.55M-4.13M-3.96M
Depreciation & Amortization56.12K36.45K23.78K15.83K27.49K28.84K35.48K27.04K00
Stock-Based Compensation2.75M2.1M1.92M1.42M853.52K468.91K410.44K511.48K0171.81K
Deferred Taxes2.6M-1.58M000-2.92M-24.27K000
Other Non-Cash Items834K49.11M-126.32K-5.23K6.38M9.1M24.27K1.79M283.08K0
Working Capital Changes965.14K-4.25M3.27M-595.68K-881.52K-52.45K461.19K-426.69K-262.73K970.98K
Change in Receivables0-3M3M0000000
Change in Inventory0-243.67K8.18K0000000
Change in Payables943.91K243.67K-8.18K-343.88K-227.96K-378.11K457.13K-347.95K-263.57K84.68K
Cash from Investing+6.22K-16.79K-9.26K22.5K2K00-500K00
Capital Expenditures-1.66K-16.79K-9.26K0000-500K00
CapEx % of Revenue-0.01%0%----0.29%0%-
Acquisitions----------
Investments----------
Other Investing7.88K0022.5K2K00000
Cash from Financing+3M12.72M1251.48M16.13M5.43M11.45M000
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing08.97M-1251.48M6.21K03.68K000
Net Change in Cash----------
Free Cash Flow+-5.3M-8.8M1.48M-6.46M-6.4M-4.27M-4.74M-5.15M-4.11M-2.82M
FCF Margin %--2.93%0.2%--374.98%-9.77%-4.08%-3.02%-1.62%-1.13%
FCF Growth %0.57%-0.66%1.17%-5.35%0.01%0.33%-0.11%-0.09%0.2%0.32%
FCF per Share-150.64-142.1820.56-85.50-22.43-6.68-4.61-3.62-2.69-1.83
FCF Conversion (FCF/Net Income)0.42x0.16x-0.42x0.89x0.50x0.39x0.84x0.71x1.00x0.71x
Interest Paid0000800000
Taxes Paid0000000000

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-146.38%-475.95%-23.6%-60.3%-94.19%-74.03%-36.88%-40.9%-35.27%-50.12%
Return on Invested Capital (ROIC)-96.67%-374.59%-25.63%-60.27%-119.27%-274.51%-929.13%-1385.82%-497.16%-964.01%
Gross Margin-98.78%97.94%-100%100%100%100%100%100%
Net Margin--1806.87%-47.4%--74856.59%-2493.11%-486.36%-383.87%-162.78%-158.39%
Debt / Equity0.06x---0.00x0.01x0.00x---
Interest Coverage-36.79x-65.01x-1963.02x-301.53x------
FCF Conversion0.42x0.16x-0.42x0.89x0.50x0.39x0.84x0.71x1.00x0.71x
Revenue Growth--152.83%-100%-2460.31%165.64%47.06%48.8%-1.56%

Revenue by Segment

2020
Royalty Revenue437K
Royalty Revenue Growth-

Frequently Asked Questions

Growth & Financials

Xenetic Biosciences, Inc. (XBIO) reported $2.9M in revenue for fiscal year 2024. This represents a 874% increase from $0.3M in 2012.

Xenetic Biosciences, Inc. (XBIO) saw revenue decline by 1.6% over the past year.

Xenetic Biosciences, Inc. (XBIO) reported a net loss of $3.2M for fiscal year 2024.

Dividend & Returns

Xenetic Biosciences, Inc. (XBIO) has a return on equity (ROE) of -50.1%. Negative ROE indicates the company is unprofitable.

Xenetic Biosciences, Inc. (XBIO) had negative free cash flow of $2.7M in fiscal year 2024, likely due to heavy capital investments.

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