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Zai Lab Limited (ZLAB) 10-Year Financial Performance & Capital Metrics

ZLAB •
HealthcareBiotechnologyCommercial Specialty Pharma
AboutZai Lab Limited develops and commercializes therapies to treat oncology, autoimmune disorders, infectious diseases, and neuroscience primarily in Mainland China and Hong Kong. The company's commercial products include Zejula, a once-daily small-molecule poly polymerase 1/2 inhibitor; Optune, a device that delivers tumor treating fields; NUZYRA for acute bacterial skin and skin structure infections, and community acquired bacterial pneumonia; and Qinlock to treat gastrointestinal stromal tumors. It also develops Odronextamab to treat follicular lymphoma, diffuse large B-cell lymphoma, and other B-celllymphomas; Repotrectinib, a tyrosine kinase inhibitor (TKI) to target ROS1 and TRK A/B/C in TKI-naïve- or -pretreated cancer patients; Margetuximab for the treatment of breast and gastroesophageal cancers; Adagrasib for treating KRAS-G12C-mutated NSCLC, colorectal cancer, pancreatic cancer, and other solid tumors; and Bemarituzumab to treat gastric and gastroesophageal junction cancer. In addition, the company develops CLN-081 for the treatment of patients with EGFR exon 20 insertion NSCLC; Elzovantinib, an orally bioavailable multi-targeted kinase inhibitor; Tebotelimab, a tetravalent IgG4 monoclonal antibody; Retifanlimab that inhibits interactions between PD-1 and its ligands; ZL-2309, an orally active, selective, and ATP-competitive cell division cycle 7 (CDC7) kinase inhibitor; ZL-1201, a humanized IgG4 monoclonal antibody; Efgartigimod to reduce disease-causing immunoglobulin G antibodies; ZL-1102, a human nanobody targeting interleukin- 17A; KarXT for the treatment of psychiatric and neurological conditions; ZL-2313, an investigational inhibitor of triple-mutant EGFR harboring; ZL-2314, an investigational inhibitor of double-mutant EGFR harboring; and Sulbactam/durlobactam for the treatment of serious infections caused by Acinetobacter. Zai Lab Limited was incorporated in 2013 and is headquartered in Shanghai, China.Show more
  • Revenue $460M +15.3%
  • EBITDA -$229M +12.4%
  • Net Income -$176M +31.7%
  • EPS (Diluted) -1.60 +38.5%
  • Gross Margin 58.6% -6.9%
  • EBITDA Margin -49.86% +24.0%
  • Operating Margin -49.86% +29.5%
  • Net Margin -38.15% +40.8%
  • ROE -22.56% +28.2%
  • ROIC -42.76% +42.8%
  • Debt/Equity 0.31 +71.7%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Strong 5Y sales CAGR of 56.5%

✗Weaknesses

  • ✗Weak Piotroski F-Score: 3/9
  • ✗Negative free cash flow
  • ✗Shares diluted 10.7% in last year
  • ✗Trading more than 30% below 52-week high

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y56.54%
3Y28.86%
TTM15.33%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM31.72%

EPS CAGR

10Y-
5Y-
3Y-
TTM91.49%

ROCE

10Y Avg-46.93%
5Y Avg-36.99%
3Y Avg-33.02%
Latest-27.94%

Peer Comparison

Commercial Specialty Pharma
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
ALKSAlkermes plc4.98B30.1021.05-5.25%16.37%13.28%0.01%0.04
ADMAADMA Biologics, Inc.3.71B15.5719.2265.15%42.87%48.57%2.97%0.24
UTHRUnited Therapeutics Corporation21.99B503.9018.0910.61%41.94%18.81%4.73%
PCSAProcessa Pharmaceuticals, Inc.114.71M2.17-0.56-221.71%0.04
UNCYUnicycive Therapeutics, Inc.144.49M6.93-1.24-100%-89.15%0.10
PTHSPelthos Therapeutics Inc.85.29M26.36-1.95-318.41%-40.48%
MISTMilestone Pharmaceuticals Inc.145.64M1.71-2.55-100%-282.97%4.17
AMRNAmarin Corporation plc5.74B13.80-3.45-25.51%-38.01%-18.78%0.02

Compare ZLAB vs Peers

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Profit & Loss

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Sales/Revenue+00129.45K12.98M48.96M144.31M215.04M266.72M398.99M460.16M
Revenue Growth %---9930.55%277.04%194.77%49.01%24.03%49.59%15.33%
Cost of Goods Sold+0043.59K3.75M239.45M52.24M74.02M95.82M147.86M190.52M
COGS % of Revenue--33.67%28.87%489.09%36.2%34.42%35.92%37.06%41.4%
Gross Profit+0085.86K9.24M-190.49M92.07M141.02M170.9M251.13M269.64M
Gross Margin %--66.33%71.13%-389.09%63.8%65.58%64.08%62.94%58.6%
Gross Profit Growth %---10656.73%-2162.47%148.34%53.16%21.19%46.94%7.37%
Operating Expenses+38.53M51.39M141.85M212.43M111.31M792.14M545.38M537.48M533.25M498.51M
OpEx % of Revenue--109580.34%1636.01%227.36%548.91%253.62%201.51%133.65%108.33%
Selling, General & Admin6.38M12.05M21.58M70.21M111.31M218.83M258.97M281.61M298.74M277.61M
SG&A % of Revenue--16667.12%540.72%227.36%151.64%120.43%105.58%74.87%60.33%
Research & Development32.15M39.34M120.28M142.22M222.71M573.31M286.41M265.87M234.5M220.9M
R&D % of Revenue--92913.22%1095.29%454.9%397.27%133.19%99.68%58.77%48.01%
Other Operating Expenses0058.78K0-222.71M00-10M00
Operating Income+-38.53M-51.39M-141.77M-203.2M-301.8M-700.06M-404.36M-366.57M-282.12M-229.43M
Operating Margin %---109514.01%-1564.88%-616.45%-485.1%-188.04%-137.44%-70.71%-49.86%
Operating Income Growth %-135.66%-33.38%-175.86%-43.33%-48.53%-131.96%42.24%9.34%23.04%18.67%
EBITDA+-38.33M-50.84M-140.12M-199.43M-297.16M-693.58M-396.13M-357.54M-261.84M-229.43M
EBITDA Margin %---108239.58%-1535.88%-606.97%-480.61%-184.21%-134.05%-65.63%-49.86%
EBITDA Growth %-136.27%-32.64%-175.59%-42.33%-49.01%-133.4%42.89%9.74%26.77%12.38%
D&A (Non-Cash Add-back)199K548K1.65M3.77M4.64M6.49M8.23M9.03M20.27M0
EBIT-38.53M-51.39M-138.45M-194.03M-301.8M-695.95M-443.06M-374.14M-254.85M0
Net Interest Income+003.22M7.94M4.94M2.19M14.58M39.8M34.85M0
Interest Income403.27K527.35K3.26M8.23M5.12M2.19M14.58M39.8M37.1M33.05M
Interest Expense0039.67K293K181K0002.25M-5.21M
Other Income/Expense1.02M1.01M3.28M-2.83M32.9M-3.35M-38.93M31.95M25.01M50.97M
Pretax Income+-37.51M-50.13M-138.49M-206.02M-268.9M-703.41M-443.29M-334.62M-257.1M-178.46M
Pretax Margin %---106980.46%-1586.66%-549.26%-487.43%-206.14%-125.46%-64.44%-38.78%
Income Tax+0477.7K3.32M-10.95M01.06M000-2.93M
Effective Tax Rate %100%100.5%100.42%94.68%100%100.15%100%100%100%98.36%
Net Income+-37.51M-50.38M-139.07M-195.07M-268.9M-704.47M-443.29M-334.62M-257.1M-175.54M
Net Margin %---107433.56%-1502.31%-549.26%-488.16%-206.14%-125.46%-64.44%-38.15%
Net Income Growth %-108.15%-34.31%-176.03%-40.26%-37.85%-161.98%37.08%24.51%23.17%31.72%
Net Income (Continuing)-37.51M-50.38M-139.07M-195.07M-268.9M-704.47M-443.29M-334.62M-257.1M-175.54M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-39.70-23.20-26.40-30.30-34.60-75.80-46.30-34.60-2.60-1.60
EPS Growth %-91.79%41.56%-13.79%-14.77%-14.19%-119.08%38.92%25.27%92.49%38.46%
EPS (Basic)-39.70-23.20-26.40-30.30-34.60-75.80-46.30-34.60-2.60-1.60
Diluted Shares Outstanding943.9K2.18M5.26M6.44M7.77M9.3M9.58M9.66M98.95M109.53M
Basic Shares Outstanding943.9K2.18M5.26M6.44M7.77M9.3M9.58M9.66M98.95M109.53M
Dividend Payout Ratio----------

Balance Sheet

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Total Current Assets+84.09M230.61M269.14M292.46M1.22B1.5B1.12B939.61M1.05B1.02B
Cash & Short-Term Investments83.95M229.66M263.3M275.93M1.19B1.41B1.01B806.45M779.67M689.57M
Cash Only83.95M229.66M62.95M75.93M442.12M964.1M1.01B790.15M449.67M679.57M
Short-Term Investments00200.35M200M744.68M445M016.3M330M10M
Accounts Receivable0090K3.79M5.17M54.81M48.57M65.33M89.41M106.12M
Days Sales Outstanding--253.76106.5638.51138.6382.4489.4181.7984.17
Inventory003.82K6M13.14M18.95M31.62M44.83M39.88M74.75M
Days Inventory Outstanding--32584.6720.04132.41155.93170.7698.43143.2
Other Current Assets00-60300035.67M23M141.53M148.85M
Total Non-Current Assets+4.81M19.02M32.84M62.69M81.6M109.08M95.8M96.69M135.27M153.1M
Property, Plant & Equipment2.66M11.98M20.77M36.86M47.14M58.28M78.77M68.69M69.47M66.54M
Fixed Asset Turnover--0.01x0.35x1.04x2.48x2.73x3.88x5.74x6.92x
Goodwill0000000000
Intangible Assets7K20.09K321.57K8.8M9.44M9.66M8.4M16.46M58.93M76.14M
Long-Term Investments500K1.65M3.15M2.4M1.28M15.61M6.43M9.22M3.12M0
Other Non-Current Assets3.06M5.5M8.88M14.62M23.75M25.53M2.2M2.32M3.75M7.02M
Total Assets+88.91M249.63M301.99M355.15M1.3B1.61B1.22B1.04B1.19B1.17B
Asset Turnover--0.00x0.04x0.04x0.09x0.18x0.26x0.34x0.39x
Asset Growth %537.79%180.78%20.97%17.61%265.37%24.07%-24.21%-15.07%14.42%-1.13%
Total Current Liabilities+5.17M12.07M48.84M46.63M98.04M192.9M139.84M203.07M299.38M416.17M
Accounts Payable523.34K8.97M37.43M22.66M62.64M126.16M65.97M112.99M100.91M141.61M
Days Payables Outstanding--313.44K2.21K95.49881.52325.33430.43249.09271.29
Short-Term Debt003.64M6.45M0000131.71M210.87M
Deferred Revenue (Current)00000000027.33M
Other Current Liabilities4.05M778.96K2.5M2.39M4.57M4.42M4.05M5.35M6.35M177.96M
Current Ratio16.25x19.11x5.51x6.27x12.40x7.78x8.04x4.63x3.51x2.45x
Quick Ratio16.25x19.11x5.51x6.14x12.27x7.68x7.81x4.41x3.38x2.27x
Cash Conversion Cycle---313.15K-1.52K-36.94-610.48-86.96-170.26-68.86-43.92
Total Non-Current Liabilities+135.29M2.39M2.06M13.86M30.25M37.1M34.7M37.11M45.47M40.72M
Long-Term Debt00000000013.38M
Capital Lease Obligations00010.98M13.39M9.61M13.34M8.05M13.71M0
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities134.51M000000325K325K27.33M
Total Liabilities140.46M14.46M50.91M60.49M128.29M230M174.54M240.18M344.86M456.88M
Total Debt+003.64M21.78M18.6M15.54M20.39M15.15M153.47M224.26M
Net Debt-83.95M-229.66M-59.31M-54.15M-423.52M-948.56M-988.08M-775M-296.2M-455.31M
Debt / Equity--0.01x0.07x0.02x0.01x0.02x0.02x0.18x0.31x
Debt / EBITDA----------
Net Debt / EBITDA----------
Interest Coverage---3573.50x-693.50x-1667.41x----125.16x-
Total Equity+-51.55M235.17M251.08M294.66M1.17B1.38B1.05B796.12M840.9M715.5M
Equity Growth %-180.63%556.18%6.77%17.36%296.85%18.01%-24.23%-23.86%5.62%-14.91%
Book Value per Share-54.62108.1147.7345.78150.56148.39109.1482.388.506.53
Total Shareholders' Equity-51.55M235.17M251.08M294.66M1.17B1.38B1.05B796.12M840.9M715.5M
Common Stock5793K3.48K4K5K6K6K6K7K7K
Retained Earnings-60.17M-110.55M-249.63M-444.7M-713.6M-1.42B-1.86B-2.2B-2.45B-2.63B
Treasury Stock00000-4.28M-11.86M-20.84M-20.84M0
Accumulated OCI-698.53K449.91K2.66M4.62M-14.52M-23.64M25.68M37.63M50.52M29.7M
Minority Interest0000000000

Cash Flow

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024Dec 2025
Cash from Operations+-32.16M-32.37M-97.54M-191.01M-216.06M-549.23M-367.64M-198.18M-214.87M-150.79M
Operating CF Margin %---75346.86%-1471.04%-441.31%-380.59%-170.96%-74.3%-53.85%-32.77%
Operating CF Growth %-180.49%-0.65%-201.35%-95.83%-13.11%-154.21%33.06%46.09%-8.42%29.82%
Net Income-37.51M-50.38M-139.07M-195.07M-268.9M-704.47M-443.29M-334.62M-257.1M-175.54M
Depreciation & Amortization199K548.13K1.65M3.77M4.64M6.49M8.23M9.03M11.86M15.01M
Stock-Based Compensation4.93M9.93M12.23M20.29M24.83M40.71M61.3M79.63M70.65M65.6M
Deferred Taxes00587.25K767K1.13M17.08M000-3.34M
Other Non-Cash Items1.92M62.61K-312K2.52M4.01M67.85M72.36M8.17M28.12M-52.52M
Working Capital Changes-1.69M7.48M27.38M-23.28M18.25M23.11M-66.25M39.61M-68.39M0
Change in Receivables00-89.71K-3.7M-1.38M-42.32M25.14M-17.69M-26.58M-18.93M
Change in Inventory00-3.82K-6M-7.17M-7.17M-15.38M-14.91M3.9M12.29M
Change in Payables-929.72K8.44M28.46M-14.77M39.98M63.52M-53.77M36.8M-2.21M19.93M
Cash from Investing+-2.73M-10.43M-212.55M-14.89M-554.83M249.96M420.02M-10.78M-375.19M307.87M
Capital Expenditures-2.23M-9.12M-10.12M-15.24M-10.67M-18.95M-24.59M-7.21M-5.66M-8.1M
CapEx % of Revenue--7815.9%117.38%21.79%13.13%11.43%2.7%1.42%1.76%
Acquisitions0-1.9M-2.09M9.21M539K-30M0029K0
Investments----------
Other Investing-505.62K68.1K-102.83K-9.21M-539K3K-399K12.74M-55.86M-5.24M
Cash from Financing+106.2M187.86M144.15M219.3M1.13B820.2M-1.73M-6.43M349.89M72.35M
Debt Issued (Net)003.64M2.9M-6.53M000131.32M0
Equity Issued (Net)1000K1000K1000K1000K1000K1000K001000K0
Dividends Paid0000000000
Share Repurchases0000000000
Other Financing0-1.67M-496.2K201K1.28M1.33M-1.73M-6.43M1.22M72.35M
Net Change in Cash70.79M145.71M-166.71M13.49M366.42M522.04M44.37M-218.01M-240.48M229.91M
Free Cash Flow+-34.39M-41.48M-107.66M-206.25M-226.72M-568.18M-392.63M-206.67M-276.39M-158.89M
FCF Margin %---83162.76%-1588.42%-463.1%-393.72%-182.58%-77.49%-69.27%-34.53%
FCF Growth %-181.79%-20.64%-159.51%-91.59%-9.93%-150.6%30.9%47.36%-33.74%42.51%
FCF per Share-36.43-19.07-20.46-32.04-29.19-61.10-40.98-21.39-2.79-1.45
FCF Conversion (FCF/Net Income)0.86x0.64x0.70x0.98x0.80x0.78x0.83x0.59x0.84x0.86x
Interest Paid000000002.02M0
Taxes Paid0000000000

Key Ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)--54.88%-57.2%-71.49%-36.74%-55.27%-36.55%-36.34%-31.41%-22.56%
Return on Invested Capital (ROIC)--699.41%-107.79%-70.51%-45.9%-89.2%-124.06%-699.25%-74.79%-42.76%
Gross Margin--66.33%71.13%-389.09%63.8%65.58%64.08%62.94%58.6%
Net Margin---107433.56%-1502.31%-549.26%-488.16%-206.14%-125.46%-64.44%-38.15%
Debt / Equity--0.01x0.07x0.02x0.01x0.02x0.02x0.18x0.31x
Interest Coverage---3573.50x-693.50x-1667.41x----125.16x-
FCF Conversion0.86x0.64x0.70x0.98x0.80x0.78x0.83x0.59x0.84x0.86x
Revenue Growth---9930.55%277.04%194.77%49.01%24.03%49.59%15.33%

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