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DNTH
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IMVT logo
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CRL
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Stock Comparison

DNTH vs BCAB vs IMVT vs RCUS vs CRL

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
DNTH
Dianthus Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.19B
5Y Perf.-39.1%
BCAB
BioAtla, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$4M
5Y Perf.-99.8%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.75B
5Y Perf.-28.8%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.35B
5Y Perf.-10.2%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$9.06B
5Y Perf.-24.7%

DNTH vs BCAB vs IMVT vs RCUS vs CRL — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
DNTH logoDNTH
BCAB logoBCAB
IMVT logoIMVT
RCUS logoRCUS
CRL logoCRL
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyMedical - Diagnostics & Research
Market Cap$3.19B$4M$6.75B$2.35B$9.06B
Revenue (TTM)$1M$2M$0.00$236M$4.03B
Net Income (TTM)$-11M$-51M$-506M$-369M$-185M
Gross Margin94.3%106.0%90.7%31.9%
Operating Margin-143.2%-25.2%-168.6%11.8%
Forward P/E17.0x
Total Debt$1M$6M$72K$99M$3.07B
Cash & Equiv.$51M$7M$902M$222M$214M

DNTH vs BCAB vs IMVT vs RCUS vs CRLLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

DNTH
BCAB
IMVT
RCUS
CRL
StockDec 20Jun 26Return
Dianthus Therapeuti… (DNTH)10060.9-39.1%
BioAtla, Inc. (BCAB)1000.2-99.8%
Immunovant, Inc. (IMVT)10071.2-28.8%
Arcus Biosciences, … (RCUS)10089.8-10.2%
Charles River Labor… (CRL)10075.3-24.7%

Price return only. Dividends and distributions are not included.

Quick Verdict: DNTH vs BCAB vs IMVT vs RCUS vs CRL

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: DNTH leads in 2 of 6 categories (5-stock set), making it the strongest pick for recent price momentum and sentiment and operational efficiency and capital deployment. BioAtla, Inc. is the stronger pick specifically for capital preservation and lower volatility. IMVT and CRL also each lead in at least one category. As sector peers, any of these can serve as alternatives in the same allocation.
🥇DNTH emerged as the overall leader. Track its performance:
DNTH
Dianthus Therapeutics, Inc.
The Defensive Pick

DNTH carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and defensive.

  • Lower volatility, beta 1.29, Low D/E 0.3%, current ratio 13.32x
  • Beta 1.29, current ratio 13.32x
  • +321.9% vs BCAB's -84.6%
  • -1.7% ROA vs BCAB's -309.4%
Best for: sleep-well-at-night and defensive
BCAB
BioAtla, Inc.
The Income Pick

BCAB is the #2 pick in this set and the best alternative if income & stability is your priority.

  • beta 0.36
  • Beta 0.36 vs RCUS's 1.98
Best for: income & stability
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT ranks third and is worth considering specifically for long-term compounding.

  • 230.5% 10Y total return vs CRL's 123.0%
  • 2.6% margin vs BCAB's -25.3%
Best for: long-term compounding
RCUS
Arcus Biosciences, Inc.
The Growth Play

RCUS is the clearest fit if your priority is growth exposure.

  • Rev growth -4.3%, EPS growth -4.8%, 3Y rev CAGR 30.2%
Best for: growth exposure
CRL
Charles River Laboratories International, Inc.
The Growth Leader

CRL is the clearest fit if your priority is growth.

  • -0.9% revenue growth vs BCAB's -81.8%
Best for: growth
See the full category breakdown
CategoryWinnerWhy
GrowthCRL logoCRL-0.9% revenue growth vs BCAB's -81.8%
Quality / MarginsIMVT logoIMVT2.6% margin vs BCAB's -25.3%
Stability / SafetyBCAB logoBCABBeta 0.36 vs RCUS's 1.98
DividendsTieNone of these 5 stocks pay a meaningful dividend
Momentum (1Y)DNTH logoDNTH+321.9% vs BCAB's -84.6%
Efficiency (ROA)DNTH logoDNTH-1.7% ROA vs BCAB's -309.4%

DNTH vs BCAB vs IMVT vs RCUS vs CRL — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

DNTHDianthus Therapeutics, Inc.
FY 2025
License
100.0%$2M
BCABBioAtla, Inc.

Segment breakdown not available.

IMVTImmunovant, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M
CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M

DNTH vs BCAB vs IMVT vs RCUS vs CRL — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLCRLLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

CRL leads this category, winning 4 of 6 comparable metrics.

CRL and IMVT operate at a comparable scale, with $4.0B and $0 in trailing revenue. CRL is the more profitable business, keeping -4.6% of every revenue dollar as net income compared to BCAB's -25.3%. On growth, CRL holds the edge at +1.2% YoY revenue growth, suggesting stronger near-term business momentum.

MetricDNTH logoDNTHDianthus Therapeu…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…
RevenueTrailing 12 months$1M$2M$0$236M$4.0B
EBITDAEarnings before interest/tax-$191M-$51M-$532M-$391M$824M
Net IncomeAfter-tax profit-$11M-$51M-$506M-$369M-$185M
Free Cash FlowCash after capex-$130M-$23M-$407M-$489M$391M
Gross MarginGross profit ÷ Revenue+94.3%+106.0%+90.7%+31.9%
Operating MarginEBIT ÷ Revenue-143.2%-25.2%-168.6%+11.8%
Net MarginNet income ÷ Revenue-8.5%-25.3%-156.4%-4.6%
FCF MarginFCF ÷ Revenue-97.7%-11.5%-2.1%+9.7%
Rev. Growth (YoY)Latest quarter vs prior year-60.2%-39.3%+1.2%
EPS Growth (YoY)Latest quarter vs prior year-3.7%+67.5%-14.1%+10.5%-160.0%
CRL leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

CRL leads this category, winning 2 of 3 comparable metrics.
MetricDNTH logoDNTHDianthus Therapeu…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…
Market CapShares × price$3.2B$4M$6.8B$2.3B$9.1B
Enterprise ValueMkt cap + debt − cash$3.1B$4M$5.8B$2.2B$11.9B
Trailing P/EPrice ÷ TTM EPS-18.20x-0.07x-11.87x-7.08x-64.63x
Forward P/EPrice ÷ next-FY EPS est.16.95x
PEG RatioP/E ÷ EPS growth rate
EV / EBITDAEnterprise value multiple13.07x
Price / SalesMarket cap ÷ Revenue1567.68x2.24x9.50x2.26x
Price / BookPrice ÷ Book value/share5.86x7.04x3.97x2.90x
Price / FCFMarket cap ÷ FCF17.47x
CRL leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

CRL leads this category, winning 4 of 9 comparable metrics.

DNTH delivers a -1.8% return on equity — every $100 of shareholder capital generates $-2 in annual profit, vs $-69 for RCUS. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to CRL's 0.95x. On the Piotroski fundamental quality scale (0–9), CRL scores 4/9 vs RCUS's 0/9, reflecting mixed financial health.

MetricDNTH logoDNTHDianthus Therapeu…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…
ROE (TTM)Return on equity-1.8%-68.2%-69.0%-5.7%
ROA (TTM)Return on assets-1.7%-3.1%-62.2%-35.3%-2.5%
ROICReturn on invested capital-34.4%-64.1%+6.3%
ROCEReturn on capital employed-41.6%-4.0%-68.3%-42.1%+8.1%
Piotroski ScoreFundamental quality 0–922204
Debt / EquityFinancial leverage0.00x0.00x0.16x0.95x
Net DebtTotal debt minus cash-$50M-$918,000-$902M-$123M$2.9B
Cash & Equiv.Liquid assets$51M$7M$902M$222M$214M
Total DebtShort + long-term debt$1M$6M$72,000$99M$3.1B
Interest CoverageEBIT ÷ Interest expense-13.38x4.29x
CRL leads this category, winning 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

DNTH leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $30,700 today (with dividends reinvested), compared to $14 for BCAB. Over the past 12 months, DNTH leads with a +321.9% total return vs BCAB's -84.6%. The 3-year compound annual growth rate (CAGR) favors DNTH at 89.0% vs BCAB's -73.3% — a key indicator of consistent wealth creation.

MetricDNTH logoDNTHDianthus Therapeu…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…
YTD ReturnYear-to-date+92.7%-86.7%+26.9%+0.0%-7.1%
1-Year ReturnPast 12 months+321.9%-84.6%+103.6%+156.6%+24.5%
3-Year ReturnCumulative with dividends+574.8%-98.1%+51.6%+15.9%-8.5%
5-Year ReturnCumulative with dividends-58.7%-99.9%+207.0%-6.4%-46.6%
10-Year ReturnCumulative with dividends-67.1%-99.8%+230.5%+37.1%+123.0%
CAGR (3Y)Annualised 3-year return+89.0%-73.3%+14.9%+5.0%-2.9%
DNTH leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

Evenly matched — BCAB and IMVT each lead in 1 of 2 comparable metrics.

BCAB is the less volatile stock with a 0.36 beta — it tends to amplify market swings less than RCUS's 1.98 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. IMVT currently trades 90.6% from its 52-week high vs BCAB's 5.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricDNTH logoDNTHDianthus Therapeu…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…
Beta (5Y)Sensitivity to S&P 5001.29x0.36x1.67x1.98x1.42x
52-Week HighHighest price in past year$96.50$71.50$36.27$28.72$228.88
52-Week LowLowest price in past year$16.64$0.33$14.32$7.91$143.06
% of 52W HighCurrent price vs 52-week peak+79.2%+5.0%+90.6%+81.1%+82.2%
RSI (14)Momentum oscillator 0–10037.843.151.939.359.7
Avg Volume (50D)Average daily shares traded674K44K1.9M1.1M769K
Evenly matched — BCAB and IMVT each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: DNTH as "Buy", BCAB as "Buy", IMVT as "Buy", RCUS as "Buy", CRL as "Buy". Consensus price targets imply 6922.5% upside for BCAB (target: $250) vs 13.4% for CRL (target: $213).

MetricDNTH logoDNTHDianthus Therapeu…BCAB logoBCABBioAtla, Inc.IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$111.91$250.00$43.67$31.17$213.17
# AnalystsCovering analysts109231837
Dividend YieldAnnual dividend ÷ price
Dividend StreakConsecutive years of raises1
Dividend / ShareAnnual DPS
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+4.0%
Insufficient data to determine a leader in this category.
Key Takeaway

CRL leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). DNTH leads in 1 (Total Returns). 1 tied.

Best OverallCharles River Laboratories … (CRL)Leads 3 of 6 categories
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DNTH vs BCAB vs IMVT vs RCUS vs CRL: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is DNTH or BCAB or IMVT or RCUS or CRL a better buy right now?

For growth investors, Charles River Laboratories International, Inc.

(CRL) is the stronger pick with -0. 9% revenue growth year-over-year, versus -81. 8% for BioAtla, Inc. (BCAB). Analysts rate Dianthus Therapeutics, Inc. (DNTH) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — DNTH or BCAB or IMVT or RCUS or CRL?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +207. 0%, compared to -99. 9% for BioAtla, Inc. (BCAB). Over 10 years, the gap is even starker: IMVT returned +230. 5% versus BCAB's -99. 8%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — DNTH or BCAB or IMVT or RCUS or CRL?

By beta (market sensitivity over 5 years), BioAtla, Inc.

(BCAB) is the lower-risk stock at 0. 36β versus Arcus Biosciences, Inc. 's 1. 98β — meaning RCUS is approximately 446% more volatile than BCAB relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 95% for Charles River Laboratories International, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — DNTH or BCAB or IMVT or RCUS or CRL?

By revenue growth (latest reported year), Charles River Laboratories International, Inc.

(CRL) is pulling ahead at -0. 9% versus -81. 8% for BioAtla, Inc. (BCAB). On earnings-per-share growth, the picture is similar: BioAtla, Inc. grew EPS 29. 9% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — DNTH or BCAB or IMVT or RCUS or CRL?

Immunovant, Inc.

(IMVT) is the more profitable company, earning 0. 0% net margin versus -79. 7% for Dianthus Therapeutics, Inc. — meaning it keeps 0. 0% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: CRL leads at 12. 6% versus -87. 4% for DNTH. At the gross margin level — before operating expenses — DNTH leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is DNTH or BCAB or IMVT or RCUS or CRL more undervalued right now?

Analyst consensus price targets imply the most upside for BCAB: 6922.

5% to $250. 00.

07

Which pays a better dividend — DNTH or BCAB or IMVT or RCUS or CRL?

None of the stocks in this comparison currently pay a material dividend.

All are effectively zero-yield and should be held for capital appreciation rather than income.

08

Is DNTH or BCAB or IMVT or RCUS or CRL better for a retirement portfolio?

For long-horizon retirement investors, BioAtla, Inc.

(BCAB) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 36)). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 98 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (BCAB: -99. 8%, RCUS: +37. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between DNTH and BCAB and IMVT and RCUS and CRL?

Both stocks operate in the Healthcare sector, making this a peer-level intra-sector comparison — the same macro tailwinds and headwinds will affect both.

These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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