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CRL
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Stock Comparison

KZIA vs MEDP vs KO vs JPM vs CRL

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
KZIA
Kazia Therapeutics Limited

Biotechnology

HealthcareNASDAQ • AU
Market Cap$16M
5Y Perf.-91.6%
MEDP
Medpace Holdings, Inc.

Medical - Diagnostics & Research

HealthcareNASDAQ • US
Market Cap$13.35B
5Y Perf.+402.4%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+84.9%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$896.00B
5Y Perf.+241.0%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$9.03B
5Y Perf.+7.5%

KZIA vs MEDP vs KO vs JPM vs CRL — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
KZIA logoKZIA
MEDP logoMEDP
KO logoKO
JPM logoJPM
CRL logoCRL
IndustryBiotechnologyMedical - Diagnostics & ResearchBeverages - Non-AlcoholicBanks - DiversifiedMedical - Diagnostics & Research
Market Cap$16M$13.35B$355.61B$896.00B$9.03B
Revenue (TTM)$3M$2.68B$49.28B$280.33B$4.03B
Net Income (TTM)$-47M$460M$13.70B$57.05B$-185M
Gross Margin100.0%29.1%61.7%60.0%31.9%
Operating Margin-16.9%21.0%29.3%25.9%11.8%
Forward P/E27.5x25.3x14.4x16.9x
Total Debt$396K$250M$45.49B$942.38B$3.07B
Cash & Equiv.$4M$497M$10.27B$343.34B$214M

KZIA vs MEDP vs KO vs JPM vs CRLLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

KZIA
MEDP
KO
JPM
CRL
StockJun 20Jun 26Return
Kazia Therapeutics … (KZIA)1008.4-91.6%
Medpace Holdings, I… (MEDP)100502.4+402.4%
The Coca-Cola Compa… (KO)100184.9+84.9%
JPMorgan Chase & Co. (JPM)100341.0+241.0%
Charles River Labor… (CRL)100107.5+7.5%

Price return only. Dividends and distributions are not included.

Quick Verdict: KZIA vs MEDP vs KO vs JPM vs CRL

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: MEDP leads in 3 of 7 categories (5-stock set), making it the strongest pick for growth and revenue expansion and recent price momentum and sentiment. The Coca-Cola Company is the stronger pick specifically for profitability and margin quality and dividend income and shareholder returns. JPM also leads in specific categories worth noting. This set spans 3 sectors — these stocks serve different portfolio roles, not just different price points.
🥇MEDP emerged as the overall leader. Track its performance:
KZIA
Kazia Therapeutics Limited
The Healthcare Pick

KZIA lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
MEDP
Medpace Holdings, Inc.
The Growth Play

MEDP carries the broadest edge in this set and is the clearest fit for growth exposure and long-term compounding.

  • Rev growth 20.0%, EPS growth 21.0%, 3Y rev CAGR 20.1%
  • 15.8% 10Y total return vs JPM's 465.8%
  • Lower volatility, beta 1.04, Low D/E 54.6%, current ratio 0.74x
  • 20.0% revenue growth vs KZIA's -98.2%
Best for: growth exposure and long-term compounding
KO
The Coca-Cola Company
The Income Pick

KO is the #2 pick in this set and the best alternative if income & stability is your priority.

  • Dividend streak 56 yrs, beta -0.20, yield 2.5%
  • 27.8% margin vs KZIA's -18.7%
  • 2.5% yield, 56-year raise streak, vs JPM's 1.9%, (3 stocks pay no dividend)
Best for: income & stability
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM ranks third and is worth considering specifically for valuation efficiency and defensive.

  • PEG 0.81 vs KO's 2.26
  • Beta 0.94, yield 1.9%, current ratio 0.52x
  • Lower P/E (14.4x vs 16.9x)
  • Beta 0.94 vs KZIA's 2.06
Best for: valuation efficiency and defensive
CRL
Charles River Laboratories International, Inc.
The Healthcare Pick

Among these 5 stocks, CRL doesn't own a clear edge in any measured category.

Best for: healthcare exposure
See the full category breakdown
CategoryWinnerWhy
GrowthMEDP logoMEDP20.0% revenue growth vs KZIA's -98.2%
ValueJPM logoJPMLower P/E (14.4x vs 16.9x)
Quality / MarginsKO logoKO27.8% margin vs KZIA's -18.7%
Stability / SafetyJPM logoJPMBeta 0.94 vs KZIA's 2.06
DividendsKO logoKO2.5% yield, 56-year raise streak, vs JPM's 1.9%, (3 stocks pay no dividend)
Momentum (1Y)MEDP logoMEDP+53.7% vs KO's +17.2%
Efficiency (ROA)MEDP logoMEDP24.8% ROA vs KZIA's -7.8%

KZIA vs MEDP vs KO vs JPM vs CRL — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

KZIAKazia Therapeutics Limited
FY 2025
Licensing Revenue
0.0%$0
MEDPMedpace Holdings, Inc.
FY 2025
Oncology
29.5%$748M
Metabolic
29.4%$745M
Other
16.1%$409M
Central Nervous System
10.1%$255M
Cardiology
9.5%$239M
Antiviral And Anti Infective
5.3%$135M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000
CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M

KZIA vs MEDP vs KO vs JPM vs CRL — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLMEDPLAGGINGCRL

Income & Cash Flow (Last 12 Months)

Evenly matched — KZIA and KO each lead in 2 of 6 comparable metrics.

JPM is the larger business by revenue, generating $280.3B annually — 111111.0x KZIA's $3M. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to KZIA's -18.7%. On growth, MEDP holds the edge at +26.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricKZIA logoKZIAKazia Therapeutic…MEDP logoMEDPMedpace Holdings,…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …CRL logoCRLCharles River Lab…
RevenueTrailing 12 months$3M$2.7B$49.3B$280.3B$4.0B
EBITDAEarnings before interest/tax-$40M$577M$15.5B$81.4B$824M
Net IncomeAfter-tax profit-$47M$460M$13.7B$57.0B-$185M
Free Cash FlowCash after capex-$14M$745M$12.6B$100.9B$391M
Gross MarginGross profit ÷ Revenue+100.0%+29.1%+61.7%+60.0%+31.9%
Operating MarginEBIT ÷ Revenue-16.9%+21.0%+29.3%+25.9%+11.8%
Net MarginNet income ÷ Revenue-18.7%+17.2%+27.8%+20.4%-4.6%
FCF MarginFCF ÷ Revenue-5.5%+27.8%+25.5%+36.0%+9.7%
Rev. Growth (YoY)Latest quarter vs prior year-99.2%+26.5%+12.1%+1.2%
EPS Growth (YoY)Latest quarter vs prior year+79.5%+16.6%+18.2%+16.0%-160.0%
Evenly matched — KZIA and KO each lead in 2 of 6 comparable metrics.

Valuation Metrics

JPM leads this category, winning 4 of 7 comparable metrics.

At 16.0x trailing earnings, JPM trades at a 48% valuation discount to MEDP's 30.6x P/E. Adjusting for growth (PEG ratio), JPM offers better value at 0.90x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.

MetricKZIA logoKZIAKazia Therapeutic…MEDP logoMEDPMedpace Holdings,…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …CRL logoCRLCharles River Lab…
Market CapShares × price$16M$13.3B$355.6B$896.0B$9.0B
Enterprise ValueMkt cap + debt − cash$13M$13.1B$390.8B$1.50T$11.9B
Trailing P/EPrice ÷ TTM EPS-1.08x30.59x27.18x16.00x-64.44x
Forward P/EPrice ÷ next-FY EPS est.27.51x25.27x14.40x16.90x
PEG RatioP/E ÷ EPS growth rate0.96x2.43x0.90x
EV / EBITDAEnterprise value multiple23.27x26.39x18.36x13.04x
Price / SalesMarket cap ÷ Revenue530.20x5.27x7.42x3.20x2.25x
Price / BookPrice ÷ Book value/share30.06x10.40x2.47x2.89x
Price / FCFMarket cap ÷ FCF19.57x67.15x8.88x17.42x
JPM leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

MEDP leads this category, winning 6 of 9 comparable metrics.

MEDP delivers a 120.9% return on equity — every $100 of shareholder capital generates $121 in annual profit, vs $-6 for CRL. MEDP carries lower financial leverage with a 0.55x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs KZIA's 2/9, reflecting strong financial health.

MetricKZIA logoKZIAKazia Therapeutic…MEDP logoMEDPMedpace Holdings,…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …CRL logoCRLCharles River Lab…
ROE (TTM)Return on equity+120.9%+41.1%+15.9%-5.7%
ROA (TTM)Return on assets-7.8%+24.8%+13.1%+1.3%-2.5%
ROICReturn on invested capital+154.9%+15.8%+4.5%+6.3%
ROCEReturn on capital employed+65.7%+17.3%+8.9%+8.1%
Piotroski ScoreFundamental quality 0–926754
Debt / EquityFinancial leverage0.55x1.33x2.60x0.95x
Net DebtTotal debt minus cash-$4M-$247M$35.2B$599.0B$2.9B
Cash & Equiv.Liquid assets$4M$497M$10.3B$343.3B$214M
Total DebtShort + long-term debt$396,000$250M$45.5B$942.4B$3.1B
Interest CoverageEBIT ÷ Interest expense10.70x0.74x4.29x
MEDP leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

MEDP leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in MEDP five years ago would be worth $26,044 today (with dividends reinvested), compared to $271 for KZIA. Over the past 12 months, MEDP leads with a +53.7% total return vs KO's +17.2%. The 3-year compound annual growth rate (CAGR) favors JPM at 33.6% vs KZIA's -38.9% — a key indicator of consistent wealth creation.

MetricKZIA logoKZIAKazia Therapeutic…MEDP logoMEDPMedpace Holdings,…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …CRL logoCRLCharles River Lab…
YTD ReturnYear-to-date+185.6%-18.2%+20.3%-0.5%-7.4%
1-Year ReturnPast 12 months+45.9%+53.7%+17.2%+21.8%+23.5%
3-Year ReturnCumulative with dividends-77.2%+114.4%+47.0%+138.2%-8.7%
5-Year ReturnCumulative with dividends-97.3%+160.4%+65.6%+118.2%-47.2%
10-Year ReturnCumulative with dividends-96.5%+1581.7%+121.1%+465.8%+122.4%
CAGR (3Y)Annualised 3-year return-38.9%+28.9%+13.7%+33.6%-3.0%
MEDP leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than KZIA's 2.06 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs MEDP's 74.3% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricKZIA logoKZIAKazia Therapeutic…MEDP logoMEDPMedpace Holdings,…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …CRL logoCRLCharles River Lab…
Beta (5Y)Sensitivity to S&P 5002.06x1.04x-0.20x0.94x1.39x
52-Week HighHighest price in past year$17.40$628.92$84.04$337.25$228.88
52-Week LowLowest price in past year$4.86$294.07$65.35$262.71$143.06
% of 52W HighCurrent price vs 52-week peak+82.1%+74.3%+98.3%+95.1%+81.9%
RSI (14)Momentum oscillator 0–10053.866.260.659.160.8
Avg Volume (50D)Average daily shares traded237K365K12.7M7.0M767K
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

KO leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: MEDP as "Hold", KO as "Buy", JPM as "Buy", CRL as "Buy". Consensus price targets imply 13.7% upside for CRL (target: $213) vs 4.2% for KO (target: $86). For income investors, KO offers the higher dividend yield at 2.46% vs JPM's 1.86%.

MetricKZIA logoKZIAKazia Therapeutic…MEDP logoMEDPMedpace Holdings,…KO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …CRL logoCRLCharles River Lab…
Analyst RatingConsensus buy/hold/sellHoldBuyBuyBuy
Price TargetConsensus 12-month target$498.86$86.13$339.75$213.17
# AnalystsCovering analysts19486137
Dividend YieldAnnual dividend ÷ price+2.5%+1.9%
Dividend StreakConsecutive years of raises56151
Dividend / ShareAnnual DPS$2.04$5.95
Buyback YieldShare repurchases ÷ mkt cap0.0%+6.9%+0.2%+3.9%+4.0%
KO leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

MEDP leads in 2 of 6 categories (Profitability & Efficiency, Total Returns). KO leads in 2 (Risk & Volatility, Analyst Outlook). 1 tied.

Best OverallMedpace Holdings, Inc. (MEDP)Leads 2 of 6 categories
Loading custom metrics...

KZIA vs MEDP vs KO vs JPM vs CRL: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is KZIA or MEDP or KO or JPM or CRL a better buy right now?

For growth investors, Medpace Holdings, Inc.

(MEDP) is the stronger pick with 20. 0% revenue growth year-over-year, versus -98. 2% for Kazia Therapeutics Limited (KZIA). JPMorgan Chase & Co. (JPM) offers the better valuation at 16. 0x trailing P/E (14. 4x forward), making it the more compelling value choice. Analysts rate The Coca-Cola Company (KO) a "Buy" — based on 48 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — KZIA or MEDP or KO or JPM or CRL?

On trailing P/E, JPMorgan Chase & Co.

(JPM) is the cheapest at 16. 0x versus Medpace Holdings, Inc. at 30. 6x. On forward P/E, JPMorgan Chase & Co. is actually cheaper at 14. 4x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: JPMorgan Chase & Co. wins at 0. 81x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — KZIA or MEDP or KO or JPM or CRL?

Over the past 5 years, Medpace Holdings, Inc.

(MEDP) delivered a total return of +160. 4%, compared to -97. 3% for Kazia Therapeutics Limited (KZIA). Over 10 years, the gap is even starker: MEDP returned +1582% versus KZIA's -96. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — KZIA or MEDP or KO or JPM or CRL?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Kazia Therapeutics Limited's 2. 06β — meaning KZIA is approximately -1128% more volatile than KO relative to the S&P 500. On balance sheet safety, Medpace Holdings, Inc. (MEDP) carries a lower debt/equity ratio of 55% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.

05

Which is growing faster — KZIA or MEDP or KO or JPM or CRL?

By revenue growth (latest reported year), Medpace Holdings, Inc.

(MEDP) is pulling ahead at 20. 0% versus -98. 2% for Kazia Therapeutics Limited (KZIA). On earnings-per-share growth, the picture is similar: Kazia Therapeutics Limited grew EPS 65. 6% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, KZIA leads at 61. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — KZIA or MEDP or KO or JPM or CRL?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -492. 9% for Kazia Therapeutics Limited — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -338. 5% for KZIA. At the gross margin level — before operating expenses — KZIA leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is KZIA or MEDP or KO or JPM or CRL more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, JPMorgan Chase & Co. (JPM) is the more undervalued stock at a PEG of 0. 81x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, JPMorgan Chase & Co. (JPM) trades at 14. 4x forward P/E versus 27. 5x for Medpace Holdings, Inc. — 13. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CRL: 13. 7% to $213. 17.

08

Which pays a better dividend — KZIA or MEDP or KO or JPM or CRL?

In this comparison, KO (2.

5% yield), JPM (1. 9% yield) pay a dividend. KZIA, MEDP, CRL do not pay a meaningful dividend and should not be held primarily for income.

09

Is KZIA or MEDP or KO or JPM or CRL better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Kazia Therapeutics Limited (KZIA) carries a higher beta of 2. 06 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, KZIA: -96. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between KZIA and MEDP and KO and JPM and CRL?

These companies operate in different sectors (KZIA (Healthcare) and MEDP (Healthcare) and KO (Consumer Defensive) and JPM (Financial Services) and CRL (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: KZIA is a small-cap quality compounder stock; MEDP is a mid-cap high-growth stock; KO is a large-cap quality compounder stock; JPM is a large-cap deep-value stock; CRL is a small-cap quality compounder stock. KO, JPM pay a dividend while KZIA, MEDP, CRL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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