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KZIA
NKTR logo
NKTR
IMVT logo
IMVT
RCUS logo
RCUS
CRL logo
CRL
KO logo
KO
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Stock Comparison

KZIA vs NKTR vs IMVT vs RCUS vs CRL vs KO

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
KZIA
Kazia Therapeutics Limited

Biotechnology

HealthcareNASDAQ • AU
Market Cap$16M
5Y Perf.-91.6%
NKTR
Nektar Therapeutics

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.16B
5Y Perf.-82.9%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.90B
5Y Perf.+38.1%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.40B
5Y Perf.-3.8%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$9.03B
5Y Perf.+7.5%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+84.9%

KZIA vs NKTR vs IMVT vs RCUS vs CRL vs KO — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
KZIA logoKZIA
NKTR logoNKTR
IMVT logoIMVT
RCUS logoRCUS
CRL logoCRL
KO logoKO
IndustryBiotechnologyBiotechnologyBiotechnologyBiotechnologyMedical - Diagnostics & ResearchBeverages - Non-Alcoholic
Market Cap$16M$1.16B$6.90B$2.40B$9.03B$355.61B
Revenue (TTM)$3M$56M$0.00$236M$4.03B$49.28B
Net Income (TTM)$-47M$-158M$-506M$-369M$-185M$13.70B
Gross Margin100.0%99.4%90.7%31.9%61.7%
Operating Margin-16.9%-224.9%-168.6%11.8%29.3%
Forward P/E16.9x25.3x
Total Debt$396K$149M$72K$99M$3.07B$45.49B
Cash & Equiv.$4M$15M$902M$222M$214M$10.27B

KZIA vs NKTR vs IMVT vs RCUS vs CRL vs KOLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

KZIA
NKTR
IMVT
RCUS
CRL
KO
StockJun 20Jun 26Return
Kazia Therapeutics … (KZIA)1008.4-91.6%
Nektar Therapeutics (NKTR)10017.1-82.9%
Immunovant, Inc. (IMVT)100138.1+38.1%
Arcus Biosciences, … (RCUS)10096.2-3.8%
Charles River Labor… (CRL)100107.5+7.5%
The Coca-Cola Compa… (KO)100184.9+84.9%

Price return only. Dividends and distributions are not included.

Quick Verdict: KZIA vs NKTR vs IMVT vs RCUS vs CRL vs KO

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KO leads in 4 of 7 categories (6-stock set), making it the strongest pick for growth and revenue expansion and profitability and margin quality. Charles River Laboratories International, Inc. is the stronger pick specifically for valuation and capital efficiency and capital preservation and lower volatility. NKTR also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇KO emerged as the overall leader. Track its performance:
KZIA
Kazia Therapeutics Limited
The Healthcare Pick

KZIA lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
NKTR
Nektar Therapeutics
The Defensive Pick

NKTR ranks third and is worth considering specifically for defensive.

  • Beta 1.50, current ratio 4.97x
  • +5.8% vs KO's +17.2%
Best for: defensive
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding and sleep-well-at-night.

  • 237.9% 10Y total return vs KO's 121.1%
  • Lower volatility, beta 1.66, Low D/E 0.0%, current ratio 9.09x
Best for: long-term compounding and sleep-well-at-night
RCUS
Arcus Biosciences, Inc.
The Healthcare Pick

RCUS doesn't hold a clear category lead here; it's more of a secondary option in this specific comparison.

Best for: healthcare exposure
CRL
Charles River Laboratories International, Inc.
The Income Pick

CRL is the #2 pick in this set and the best alternative if income & stability is your priority.

  • Dividend streak 1 yrs, beta 1.39
  • Lower P/E (16.9x vs 25.3x)
  • Beta 1.39 vs KZIA's 2.06
Best for: income & stability
KO
The Coca-Cola Company
The Growth Play

KO carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 1.9%, EPS growth 23.6%, 3Y rev CAGR 3.7%
  • 1.9% revenue growth vs KZIA's -98.2%
  • 27.8% margin vs KZIA's -18.7%
  • 2.5% yield; 56-year raise streak; the other 5 pay no meaningful dividend
Best for: growth exposure
See the full category breakdown
CategoryWinnerWhy
GrowthKO logoKO1.9% revenue growth vs KZIA's -98.2%
ValueCRL logoCRLLower P/E (16.9x vs 25.3x)
Quality / MarginsKO logoKO27.8% margin vs KZIA's -18.7%
Stability / SafetyCRL logoCRLBeta 1.39 vs KZIA's 2.06
DividendsKO logoKO2.5% yield; 56-year raise streak; the other 5 pay no meaningful dividend
Momentum (1Y)NKTR logoNKTR+5.8% vs KO's +17.2%
Efficiency (ROA)KO logoKO13.1% ROA vs KZIA's -7.8%

KZIA vs NKTR vs IMVT vs RCUS vs CRL vs KO — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

KZIAKazia Therapeutics Limited
FY 2025
Licensing Revenue
0.0%$0
NKTRNektar Therapeutics
FY 2025
Non Cash Royalty Revenue Related To Sale Of Future Royalties
99.5%$55M
License Collaboration And Other Revenue
0.5%$300,000
IMVTImmunovant, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M
CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B

KZIA vs NKTR vs IMVT vs RCUS vs CRL vs KO — Financial Metrics

Side-by-side numbers across 6 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKOLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

KO leads this category, winning 4 of 6 comparable metrics.

KO and IMVT operate at a comparable scale, with $49.3B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to KZIA's -18.7%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.

MetricKZIA logoKZIAKazia Therapeutic…NKTR logoNKTRNektar Therapeuti…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…KO logoKOThe Coca-Cola Com…
RevenueTrailing 12 months$3M$56M$0$236M$4.0B$49.3B
EBITDAEarnings before interest/tax-$40M-$124M-$532M-$391M$824M$15.5B
Net IncomeAfter-tax profit-$47M-$158M-$506M-$369M-$185M$13.7B
Free Cash FlowCash after capex-$14M-$204M-$407M-$489M$391M$12.6B
Gross MarginGross profit ÷ Revenue+100.0%+99.4%+90.7%+31.9%+61.7%
Operating MarginEBIT ÷ Revenue-16.9%-2.2%-168.6%+11.8%+29.3%
Net MarginNet income ÷ Revenue-18.7%-2.8%-156.4%-4.6%+27.8%
FCF MarginFCF ÷ Revenue-5.5%-3.7%-2.1%+9.7%+25.5%
Rev. Growth (YoY)Latest quarter vs prior year-99.2%+3.8%-39.3%+1.2%+12.1%
EPS Growth (YoY)Latest quarter vs prior year+79.5%+49.7%-14.1%+10.5%-160.0%+18.2%
KO leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

CRL leads this category, winning 6 of 6 comparable metrics.

On an enterprise value basis, CRL's 13.0x EV/EBITDA is more attractive than KO's 26.4x.

MetricKZIA logoKZIAKazia Therapeutic…NKTR logoNKTRNektar Therapeuti…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…KO logoKOThe Coca-Cola Com…
Market CapShares × price$16M$1.2B$6.9B$2.4B$9.0B$355.6B
Enterprise ValueMkt cap + debt − cash$13M$1.3B$6.0B$2.3B$11.9B$390.8B
Trailing P/EPrice ÷ TTM EPS-1.08x-6.10x-12.14x-7.23x-64.44x27.18x
Forward P/EPrice ÷ next-FY EPS est.16.90x25.27x
PEG RatioP/E ÷ EPS growth rate2.43x
EV / EBITDAEnterprise value multiple13.04x26.39x
Price / SalesMarket cap ÷ Revenue530.20x21.01x9.70x2.25x7.42x
Price / BookPrice ÷ Book value/share11.15x7.19x4.05x2.89x10.40x
Price / FCFMarket cap ÷ FCF17.42x67.15x
CRL leads this category, winning 6 of 6 comparable metrics.

Profitability & Efficiency

KO leads this category, winning 6 of 9 comparable metrics.

KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-87 for NKTR. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to NKTR's 1.66x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs RCUS's 0/9, reflecting strong financial health.

MetricKZIA logoKZIAKazia Therapeutic…NKTR logoNKTRNektar Therapeuti…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…KO logoKOThe Coca-Cola Com…
ROE (TTM)Return on equity-87.0%-68.2%-69.0%-5.7%+41.1%
ROA (TTM)Return on assets-7.8%-40.7%-62.2%-35.3%-2.5%+13.1%
ROICReturn on invested capital-57.2%-64.1%+6.3%+15.8%
ROCEReturn on capital employed-55.7%-68.3%-42.1%+8.1%+17.3%
Piotroski ScoreFundamental quality 0–9222047
Debt / EquityFinancial leverage1.66x0.00x0.16x0.95x1.33x
Net DebtTotal debt minus cash-$4M$134M-$902M-$123M$2.9B$35.2B
Cash & Equiv.Liquid assets$4M$15M$902M$222M$214M$10.3B
Total DebtShort + long-term debt$396,000$149M$72,000$99M$3.1B$45.5B
Interest CoverageEBIT ÷ Interest expense-4.15x-13.38x4.29x10.70x
KO leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

NKTR leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $271 for KZIA. Over the past 12 months, NKTR leads with a +577.9% total return vs KO's +17.2%. The 3-year compound annual growth rate (CAGR) favors NKTR at 90.8% vs KZIA's -38.9% — a key indicator of consistent wealth creation.

MetricKZIA logoKZIAKazia Therapeutic…NKTR logoNKTRNektar Therapeuti…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…KO logoKOThe Coca-Cola Com…
YTD ReturnYear-to-date+185.6%+36.8%+29.8%+2.2%-7.4%+20.3%
1-Year ReturnPast 12 months+45.9%+577.9%+110.9%+154.5%+23.5%+17.2%
3-Year ReturnCumulative with dividends-77.2%+594.5%+55.0%+18.3%-8.7%+47.0%
5-Year ReturnCumulative with dividends-97.3%-77.6%+213.0%-3.1%-47.2%+65.6%
10-Year ReturnCumulative with dividends-96.5%-73.6%+237.9%+40.0%+122.4%+121.1%
CAGR (3Y)Annualised 3-year return-38.9%+90.8%+15.7%+5.8%-3.0%+13.7%
NKTR leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than KZIA's 2.06 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs NKTR's 54.5% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricKZIA logoKZIAKazia Therapeutic…NKTR logoNKTRNektar Therapeuti…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…KO logoKOThe Coca-Cola Com…
Beta (5Y)Sensitivity to S&P 5002.06x1.50x1.66x2.00x1.39x-0.20x
52-Week HighHighest price in past year$17.40$109.00$36.27$28.72$228.88$84.04
52-Week LowLowest price in past year$4.86$7.99$14.32$7.91$143.06$65.35
% of 52W HighCurrent price vs 52-week peak+82.1%+54.5%+92.7%+82.9%+81.9%+98.3%
RSI (14)Momentum oscillator 0–10053.832.157.946.560.860.6
Avg Volume (50D)Average daily shares traded237K994K1.9M1.1M767K12.7M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

KO leads this category, winning 1 of 1 comparable metric.

Analyst consensus: NKTR as "Buy", IMVT as "Buy", RCUS as "Buy", CRL as "Buy", KO as "Buy". Consensus price targets imply 151.9% upside for NKTR (target: $150) vs 4.2% for KO (target: $86). KO is the only dividend payer here at 2.46% yield — a key consideration for income-focused portfolios.

MetricKZIA logoKZIAKazia Therapeutic…NKTR logoNKTRNektar Therapeuti…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…CRL logoCRLCharles River Lab…KO logoKOThe Coca-Cola Com…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$149.60$43.67$31.00$213.17$86.13
# AnalystsCovering analysts3323183748
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises156
Dividend / ShareAnnual DPS$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%0.0%+4.0%+0.2%
KO leads this category, winning 1 of 1 comparable metric.
Key Takeaway

KO leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). CRL leads in 1 (Valuation Metrics).

Best OverallThe Coca-Cola Company (KO)Leads 4 of 6 categories
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KZIA vs NKTR vs IMVT vs RCUS vs CRL vs KO: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is KZIA or NKTR or IMVT or RCUS or CRL or KO a better buy right now?

For growth investors, The Coca-Cola Company (KO) is the stronger pick with 1.

9% revenue growth year-over-year, versus -98. 2% for Kazia Therapeutics Limited (KZIA). The Coca-Cola Company (KO) offers the better valuation at 27. 2x trailing P/E (25. 3x forward), making it the more compelling value choice. Analysts rate Nektar Therapeutics (NKTR) a "Buy" — based on 33 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — KZIA or NKTR or IMVT or RCUS or CRL or KO?

On forward P/E, Charles River Laboratories International, Inc.

is actually cheaper at 16. 9x — notably different from the trailing picture, reflecting expected earnings growth.

03

Which is the better long-term investment — KZIA or NKTR or IMVT or RCUS or CRL or KO?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +213. 0%, compared to -97. 3% for Kazia Therapeutics Limited (KZIA). Over 10 years, the gap is even starker: IMVT returned +237. 9% versus KZIA's -96. 5%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — KZIA or NKTR or IMVT or RCUS or CRL or KO?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Kazia Therapeutics Limited's 2. 06β — meaning KZIA is approximately -1128% more volatile than KO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 166% for Nektar Therapeutics — giving it more financial flexibility in a downturn.

05

Which is growing faster — KZIA or NKTR or IMVT or RCUS or CRL or KO?

By revenue growth (latest reported year), The Coca-Cola Company (KO) is pulling ahead at 1.

9% versus -98. 2% for Kazia Therapeutics Limited (KZIA). On earnings-per-share growth, the picture is similar: Kazia Therapeutics Limited grew EPS 65. 6% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, KZIA leads at 61. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — KZIA or NKTR or IMVT or RCUS or CRL or KO?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -492. 9% for Kazia Therapeutics Limited — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -338. 5% for KZIA. At the gross margin level — before operating expenses — KZIA leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is KZIA or NKTR or IMVT or RCUS or CRL or KO more undervalued right now?

On forward earnings alone, Charles River Laboratories International, Inc.

(CRL) trades at 16. 9x forward P/E versus 25. 3x for The Coca-Cola Company — 8. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for NKTR: 151. 9% to $149. 60.

08

Which pays a better dividend — KZIA or NKTR or IMVT or RCUS or CRL or KO?

In this comparison, KO (2.

5% yield) pays a dividend. KZIA, NKTR, IMVT, RCUS, CRL do not pay a meaningful dividend and should not be held primarily for income.

09

Is KZIA or NKTR or IMVT or RCUS or CRL or KO better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

20), 2. 5% yield, +121. 1% 10Y return). Kazia Therapeutics Limited (KZIA) carries a higher beta of 2. 06 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, KZIA: -96. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between KZIA and NKTR and IMVT and RCUS and CRL and KO?

These companies operate in different sectors (KZIA (Healthcare) and NKTR (Healthcare) and IMVT (Healthcare) and RCUS (Healthcare) and CRL (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

KO pays a dividend while KZIA, NKTR, IMVT, RCUS, CRL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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