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Stock Comparison

NERV vs ALTO vs ACAD vs REX vs JPM

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
NERV
Minerva Neurosciences, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$32M
5Y Perf.-84.4%
ALTO
Alto Ingredients, Inc.

Chemicals - Specialty

Basic MaterialsNASDAQ • US
Market Cap$441M
5Y Perf.+702.8%
ACAD
ACADIA Pharmaceuticals Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$3.61B
5Y Perf.-56.5%
REX
REX American Resources Corporation

Chemicals - Specialty

Basic MaterialsNYSE • US
Market Cap$1.45B
5Y Perf.+280.1%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$896.00B
5Y Perf.+241.0%

NERV vs ALTO vs ACAD vs REX vs JPM — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
NERV logoNERV
ALTO logoALTO
ACAD logoACAD
REX logoREX
JPM logoJPM
IndustryBiotechnologyChemicals - SpecialtyBiotechnologyChemicals - SpecialtyBanks - Diversified
Market Cap$32M$441M$3.61B$1.45B$896.00B
Revenue (TTM)$0.00$916M$1.10B$656M$280.33B
Net Income (TTM)$-415M$29M$376M$93M$57.05B
Gross Margin5.0%91.5%16.5%60.0%
Operating Margin2.1%7.4%11.0%25.9%
Forward P/E13.4x54.2x56.7x14.4x
Total Debt$65M$98M$52M$21M$942.38B
Cash & Equiv.$82M$26M$178M$189M$343.34B

NERV vs ALTO vs ACAD vs REX vs JPMLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

NERV
ALTO
ACAD
REX
JPM
StockJun 20Jun 26Return
Minerva Neuroscienc… (NERV)10015.6-84.4%
Alto Ingredients, I… (ALTO)100802.8+702.8%
ACADIA Pharmaceutic… (ACAD)10043.5-56.5%
REX American Resour… (REX)100380.1+280.1%
JPMorgan Chase & Co. (JPM)100341.0+241.0%

Price return only. Dividends and distributions are not included.

Quick Verdict: NERV vs ALTO vs ACAD vs REX vs JPM

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: ALTO and ACAD are tied at the top with 2 categories each (5-stock set) — the right choice depends on your priorities. ACADIA Pharmaceuticals Inc. is the stronger pick specifically for profitability and margin quality and operational efficiency and capital deployment. NERV, REX, and JPM also each lead in at least one category. This set spans 3 sectors — these stocks serve different portfolio roles, not just different price points.
NERV
Minerva Neurosciences, Inc.
The Growth Leader

NERV ranks third and is worth considering specifically for growth.

  • 121.0% revenue growth vs ALTO's -4.9%
Best for: growth
ALTO
Alto Ingredients, Inc.
The Value Play

ALTO has the current edge in this matchup, primarily because of its strength in value and momentum.

  • Lower P/E (13.4x vs 54.2x)
  • +418.2% vs ACAD's -3.0%
Best for: value and momentum
ACAD
ACADIA Pharmaceuticals Inc.
The Growth Play

ACAD is the #2 pick in this set and the best alternative if growth exposure is your priority.

  • Rev growth 11.9%, EPS growth 68.4%, 3Y rev CAGR 27.5%
  • 34.3% margin vs ALTO's 3.2%
  • 26.2% ROA vs NERV's -6.6%
Best for: growth exposure
REX
REX American Resources Corporation
The Defensive Pick

REX is the clearest fit if your priority is sleep-well-at-night and valuation efficiency.

  • Lower volatility, beta 0.22, Low D/E 3.0%, current ratio 5.94x
  • PEG 0.75 vs JPM's 0.81
  • Beta 0.22, current ratio 5.94x
  • Beta 0.22 vs NERV's 1.28
Best for: sleep-well-at-night and valuation efficiency
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM is the clearest fit if your priority is income & stability and long-term compounding.

  • Dividend streak 15 yrs, beta 0.94, yield 1.9%
  • 465.8% 10Y total return vs REX's 347.0%
  • 1.9% yield, 15-year raise streak, vs ALTO's 0.3%, (3 stocks pay no dividend)
Best for: income & stability and long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthNERV logoNERV121.0% revenue growth vs ALTO's -4.9%
ValueALTO logoALTOLower P/E (13.4x vs 54.2x)
Quality / MarginsACAD logoACAD34.3% margin vs ALTO's 3.2%
Stability / SafetyREX logoREXBeta 0.22 vs NERV's 1.28
DividendsJPM logoJPM1.9% yield, 15-year raise streak, vs ALTO's 0.3%, (3 stocks pay no dividend)
Momentum (1Y)ALTO logoALTO+418.2% vs ACAD's -3.0%
Efficiency (ROA)ACAD logoACAD26.2% ROA vs NERV's -6.6%

NERV vs ALTO vs ACAD vs REX vs JPM — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

NERVMinerva Neurosciences, Inc.

Segment breakdown not available.

ALTOAlto Ingredients, Inc.
FY 2025
Intersegment Eliminations Member
0.0%$-12,612,000
ACADACADIA Pharmaceuticals Inc.
FY 2018
Product
100.0%$224M
REXREX American Resources Corporation
FY 2025
Other Member
100.0%$399,000
JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000

NERV vs ALTO vs ACAD vs REX vs JPM — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLALTOLAGGINGNERV

Income & Cash Flow (Last 12 Months)

ACAD leads this category, winning 3 of 6 comparable metrics.

JPM and NERV operate at a comparable scale, with $280.3B and $0 in trailing revenue. ACAD is the more profitable business, keeping 34.3% of every revenue dollar as net income compared to ALTO's 3.2%. On growth, ACAD holds the edge at +9.7% YoY revenue growth, suggesting stronger near-term business momentum.

MetricNERV logoNERVMinerva Neuroscie…ALTO logoALTOAlto Ingredients,…ACAD logoACADACADIA Pharmaceut…REX logoREXREX American Reso…JPM logoJPMJPMorgan Chase & …
RevenueTrailing 12 months$0$916M$1.1B$656M$280.3B
EBITDAEarnings before interest/tax-$28M$38M$96M$89M$81.4B
Net IncomeAfter-tax profit-$415M$29M$376M$93M$57.0B
Free Cash FlowCash after capex-$5.4B$31M$212M$46M$100.9B
Gross MarginGross profit ÷ Revenue+5.0%+91.5%+16.5%+60.0%
Operating MarginEBIT ÷ Revenue+2.1%+7.4%+11.0%+25.9%
Net MarginNet income ÷ Revenue+3.2%+34.3%+14.1%+20.4%
FCF MarginFCF ÷ Revenue+3.4%+19.4%+7.0%+36.0%
Rev. Growth (YoY)Latest quarter vs prior year-0.8%+9.7%+3.6%
EPS Growth (YoY)Latest quarter vs prior year+131.3%-81.8%+119.6%+16.0%
ACAD leads this category, winning 3 of 6 comparable metrics.

Valuation Metrics

ALTO leads this category, winning 4 of 7 comparable metrics.

At 9.2x trailing earnings, ACAD trades at a 74% valuation discount to ALTO's 35.6x P/E. Adjusting for growth (PEG ratio), REX offers better value at 0.23x vs JPM's 0.90x — a lower PEG means you pay less per unit of expected earnings growth.

MetricNERV logoNERVMinerva Neuroscie…ALTO logoALTOAlto Ingredients,…ACAD logoACADACADIA Pharmaceut…REX logoREXREX American Reso…JPM logoJPMJPMorgan Chase & …
Market CapShares × price$32M$441M$3.6B$1.4B$896.0B
Enterprise ValueMkt cap + debt − cash$14M$512M$3.5B$1.3B$1.50T
Trailing P/EPrice ÷ TTM EPS-0.13x35.63x9.21x17.58x16.00x
Forward P/EPrice ÷ next-FY EPS est.13.41x54.20x56.70x14.40x
PEG RatioP/E ÷ EPS growth rate0.23x0.90x
EV / EBITDAEnterprise value multiple15.57x25.09x16.44x18.36x
Price / SalesMarket cap ÷ Revenue0.48x3.37x2.22x3.20x
Price / BookPrice ÷ Book value/share1.76x2.94x2.08x2.47x
Price / FCFMarket cap ÷ FCF50.94x34.34x29.30x8.88x
ALTO leads this category, winning 4 of 7 comparable metrics.

Profitability & Efficiency

Evenly matched — ACAD and REX each lead in 4 of 9 comparable metrics.

ACAD delivers a 35.6% return on equity — every $100 of shareholder capital generates $36 in annual profit, vs $13 for ALTO. REX carries lower financial leverage with a 0.03x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), REX scores 7/9 vs NERV's 2/9, reflecting strong financial health.

MetricNERV logoNERVMinerva Neuroscie…ALTO logoALTOAlto Ingredients,…ACAD logoACADACADIA Pharmaceut…REX logoREXREX American Reso…JPM logoJPMJPMorgan Chase & …
ROE (TTM)Return on equity+12.5%+35.6%+13.7%+15.9%
ROA (TTM)Return on assets-6.6%+7.4%+26.2%+12.1%+1.3%
ROICReturn on invested capital+1.9%+10.0%+9.1%+4.5%
ROCEReturn on capital employed-23.2%+2.3%+10.1%+8.8%+8.9%
Piotroski ScoreFundamental quality 0–925675
Debt / EquityFinancial leverage0.40x0.04x0.03x2.60x
Net DebtTotal debt minus cash-$17M$72M-$126M-$167M$599.0B
Cash & Equiv.Liquid assets$82M$26M$178M$189M$343.3B
Total DebtShort + long-term debt$65M$98M$52M$21M$942.4B
Interest CoverageEBIT ÷ Interest expense0.24x0.74x
Evenly matched — ACAD and REX each lead in 4 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

REX leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in REX five years ago would be worth $27,157 today (with dividends reinvested), compared to $1,905 for NERV. Over the past 12 months, ALTO leads with a +418.2% total return vs ACAD's -3.0%. The 3-year compound annual growth rate (CAGR) favors REX at 37.7% vs NERV's -12.1% — a key indicator of consistent wealth creation.

MetricNERV logoNERVMinerva Neuroscie…ALTO logoALTOAlto Ingredients,…ACAD logoACADACADIA Pharmaceut…REX logoREXREX American Reso…JPM logoJPMJPMorgan Chase & …
YTD ReturnYear-to-date+15.1%+114.3%-19.3%+35.6%-0.5%
1-Year ReturnPast 12 months+152.0%+418.2%-3.0%+94.9%+21.8%
3-Year ReturnCumulative with dividends-32.2%+128.9%-14.3%+160.9%+138.2%
5-Year ReturnCumulative with dividends-81.0%-9.2%-22.6%+171.6%+118.2%
10-Year ReturnCumulative with dividends-94.4%+2.3%-44.6%+347.0%+465.8%
CAGR (3Y)Annualised 3-year return-12.1%+31.8%-5.0%+37.7%+33.6%
REX leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — ALTO and REX each lead in 1 of 2 comparable metrics.

REX is the less volatile stock with a 0.22 beta — it tends to amplify market swings less than NERV's 1.28 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. ALTO currently trades 95.2% from its 52-week high vs NERV's 36.2% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricNERV logoNERVMinerva Neuroscie…ALTO logoALTOAlto Ingredients,…ACAD logoACADACADIA Pharmaceut…REX logoREXREX American Reso…JPM logoJPMJPMorgan Chase & …
Beta (5Y)Sensitivity to S&P 5001.28x0.23x1.10x0.22x0.94x
52-Week HighHighest price in past year$12.46$5.99$27.81$53.36$337.25
52-Week LowLowest price in past year$1.57$0.92$19.69$22.23$262.71
% of 52W HighCurrent price vs 52-week peak+36.2%+95.2%+75.8%+82.3%+95.1%
RSI (14)Momentum oscillator 0–10037.458.947.932.859.1
Avg Volume (50D)Average daily shares traded154K2.0M1.4M164K7.0M
Evenly matched — ALTO and REX each lead in 1 of 2 comparable metrics.

Analyst Outlook

JPM leads this category, winning 2 of 2 comparable metrics.

Analyst consensus: NERV as "Buy", ALTO as "Buy", ACAD as "Buy", REX as "Buy", JPM as "Buy". Consensus price targets imply 75.4% upside for ALTO (target: $10) vs 5.9% for JPM (target: $340). For income investors, JPM offers the higher dividend yield at 1.86% vs ALTO's 0.29%.

MetricNERV logoNERVMinerva Neuroscie…ALTO logoALTOAlto Ingredients,…ACAD logoACADACADIA Pharmaceut…REX logoREXREX American Reso…JPM logoJPMJPMorgan Chase & …
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$5.00$10.00$34.78$60.00$339.75
# AnalystsCovering analysts7237361
Dividend YieldAnnual dividend ÷ price+0.3%+1.9%
Dividend StreakConsecutive years of raises0015
Dividend / ShareAnnual DPS$0.02$5.95
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%0.0%+2.3%+3.9%
JPM leads this category, winning 2 of 2 comparable metrics.
Key Takeaway

ACAD leads in 1 of 6 categories (Income & Cash Flow). ALTO leads in 1 (Valuation Metrics). 2 tied.

Best OverallAlto Ingredients, Inc. (ALTO)Leads 1 of 6 categories
Loading custom metrics...

NERV vs ALTO vs ACAD vs REX vs JPM: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is NERV or ALTO or ACAD or REX or JPM a better buy right now?

For growth investors, ACADIA Pharmaceuticals Inc.

(ACAD) is the stronger pick with 11. 9% revenue growth year-over-year, versus -4. 9% for Alto Ingredients, Inc. (ALTO). ACADIA Pharmaceuticals Inc. (ACAD) offers the better valuation at 9. 2x trailing P/E (54. 2x forward), making it the more compelling value choice. Analysts rate Minerva Neurosciences, Inc. (NERV) a "Buy" — based on 7 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — NERV or ALTO or ACAD or REX or JPM?

On trailing P/E, ACADIA Pharmaceuticals Inc.

(ACAD) is the cheapest at 9. 2x versus Alto Ingredients, Inc. at 35. 6x. On forward P/E, Alto Ingredients, Inc. is actually cheaper at 13. 4x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: REX American Resources Corporation wins at 0. 75x versus JPMorgan Chase & Co. 's 0. 81x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — NERV or ALTO or ACAD or REX or JPM?

Over the past 5 years, REX American Resources Corporation (REX) delivered a total return of +171.

6%, compared to -81. 0% for Minerva Neurosciences, Inc. (NERV). Over 10 years, the gap is even starker: JPM returned +465. 8% versus NERV's -94. 4%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — NERV or ALTO or ACAD or REX or JPM?

By beta (market sensitivity over 5 years), REX American Resources Corporation (REX) is the lower-risk stock at 0.

22β versus Minerva Neurosciences, Inc. 's 1. 28β — meaning NERV is approximately 480% more volatile than REX relative to the S&P 500. On balance sheet safety, REX American Resources Corporation (REX) carries a lower debt/equity ratio of 3% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.

05

Which is growing faster — NERV or ALTO or ACAD or REX or JPM?

By revenue growth (latest reported year), ACADIA Pharmaceuticals Inc.

(ACAD) is pulling ahead at 11. 9% versus -4. 9% for Alto Ingredients, Inc. (ALTO). On earnings-per-share growth, the picture is similar: Alto Ingredients, Inc. grew EPS 119. 5% year-over-year, compared to -183. 5% for Minerva Neurosciences, Inc.. Over a 3-year CAGR, ACAD leads at 27. 5% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — NERV or ALTO or ACAD or REX or JPM?

ACADIA Pharmaceuticals Inc.

(ACAD) is the more profitable company, earning 36. 5% net margin versus 0. 0% for Minerva Neurosciences, Inc. — meaning it keeps 36. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JPM leads at 26. 0% versus 0. 0% for NERV. At the gross margin level — before operating expenses — ACAD leads at 91. 7%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is NERV or ALTO or ACAD or REX or JPM more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, REX American Resources Corporation (REX) is the more undervalued stock at a PEG of 0. 75x versus JPMorgan Chase & Co. 's 0. 81x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Alto Ingredients, Inc. (ALTO) trades at 13. 4x forward P/E versus 56. 7x for REX American Resources Corporation — 43. 3x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ALTO: 75. 4% to $10. 00.

08

Which pays a better dividend — NERV or ALTO or ACAD or REX or JPM?

In this comparison, JPM (1.

9% yield), ALTO (0. 3% yield) pay a dividend. NERV, ACAD, REX do not pay a meaningful dividend and should not be held primarily for income.

09

Is NERV or ALTO or ACAD or REX or JPM better for a retirement portfolio?

For long-horizon retirement investors, REX American Resources Corporation (REX) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

22), +347. 0% 10Y return). Both have compounded well over 10 years (REX: +347. 0%, NERV: -94. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between NERV and ALTO and ACAD and REX and JPM?

These companies operate in different sectors (NERV (Healthcare) and ALTO (Basic Materials) and ACAD (Healthcare) and REX (Basic Materials) and JPM (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: NERV is a small-cap quality compounder stock; ALTO is a small-cap quality compounder stock; ACAD is a small-cap deep-value stock; REX is a small-cap deep-value stock; JPM is a large-cap deep-value stock. JPM pays a dividend while NERV, ALTO, ACAD, REX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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