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PYXS
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MGNX
KO logo
KO
IMVT logo
IMVT
RCUS logo
RCUS
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Stock Comparison

PYXS vs MGNX vs KO vs IMVT vs RCUS

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
PYXS
Pyxis Oncology, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$106M
5Y Perf.-87.5%
MGNX
MacroGenics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$255M
5Y Perf.-79.5%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.22B
5Y Perf.+46.4%
IMVT
Immunovant, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.75B
5Y Perf.+309.0%
RCUS
Arcus Biosciences, Inc.

Biotechnology

HealthcareNYSE • US
Market Cap$2.35B
5Y Perf.-30.3%

PYXS vs MGNX vs KO vs IMVT vs RCUS — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
PYXS logoPYXS
MGNX logoMGNX
KO logoKO
IMVT logoIMVT
RCUS logoRCUS
IndustryBiotechnologyBiotechnologyBeverages - Non-AlcoholicBiotechnologyBiotechnology
Market Cap$106M$255M$355.22B$6.75B$2.35B
Revenue (TTM)$14M$157M$49.28B$0.00$236M
Net Income (TTM)$-82M$-70M$13.70B$-506M$-369M
Gross Margin99.8%69.9%61.7%90.7%
Operating Margin-6.2%-40.5%29.3%-168.6%
Forward P/E25.2x
Total Debt$19M$107M$45.49B$72K$99M
Cash & Equiv.$15M$57M$10.27B$902M$222M

PYXS vs MGNX vs KO vs IMVT vs RCUSLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

PYXS
MGNX
KO
IMVT
RCUS
StockOct 21Jun 26Return
Pyxis Oncology, Inc. (PYXS)10012.5-87.5%
MacroGenics, Inc. (MGNX)10020.5-79.5%
The Coca-Cola Compa… (KO)100146.4+46.4%
Immunovant, Inc. (IMVT)100409.0+309.0%
Arcus Biosciences, … (RCUS)10069.7-30.3%

Price return only. Dividends and distributions are not included.

Quick Verdict: PYXS vs MGNX vs KO vs IMVT vs RCUS

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: KO leads in 4 of 6 categories (5-stock set), making it the strongest pick for growth and revenue expansion and profitability and margin quality. Pyxis Oncology, Inc. is the stronger pick specifically for capital preservation and lower volatility. RCUS also leads in specific categories worth noting. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇KO emerged as the overall leader. Track its performance:
PYXS
Pyxis Oncology, Inc.
The Income Pick

PYXS is the #2 pick in this set and the best alternative if income & stability and sleep-well-at-night is your priority.

  • beta 1.50
  • Lower volatility, beta 1.50, Low D/E 35.0%, current ratio 3.41x
  • Beta 1.50 vs RCUS's 1.98
Best for: income & stability and sleep-well-at-night
MGNX
MacroGenics, Inc.
The Defensive Pick

MGNX is the clearest fit if your priority is defensive.

  • Beta 1.59, current ratio 5.10x
Best for: defensive
KO
The Coca-Cola Company
The Growth Play

KO carries the broadest edge in this set and is the clearest fit for growth exposure.

  • Rev growth 1.9%, EPS growth 23.6%, 3Y rev CAGR 3.7%
  • 1.9% revenue growth vs IMVT's -22.2%
  • 27.8% margin vs PYXS's -5.9%
  • 2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Best for: growth exposure
IMVT
Immunovant, Inc.
The Long-Run Compounder

IMVT is the clearest fit if your priority is long-term compounding.

  • 230.5% 10Y total return vs KO's 120.9%
Best for: long-term compounding
RCUS
Arcus Biosciences, Inc.
The Momentum Pick

RCUS ranks third and is worth considering specifically for momentum.

  • +156.6% vs KO's +17.4%
Best for: momentum
See the full category breakdown
CategoryWinnerWhy
GrowthKO logoKO1.9% revenue growth vs IMVT's -22.2%
Quality / MarginsKO logoKO27.8% margin vs PYXS's -5.9%
Stability / SafetyPYXS logoPYXSBeta 1.50 vs RCUS's 1.98
DividendsKO logoKO2.5% yield; 56-year raise streak; the other 4 pay no meaningful dividend
Momentum (1Y)RCUS logoRCUS+156.6% vs KO's +17.4%
Efficiency (ROA)KO logoKO13.1% ROA vs PYXS's -85.0%, ROIC 15.8% vs -71.1%

PYXS vs MGNX vs KO vs IMVT vs RCUS — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

PYXSPyxis Oncology, Inc.
FY 2025
Milestone Revenue
100.0%$3M
MGNXMacroGenics, Inc.
FY 2025
Revenue From Collaborative Agreements
62.4%$87M
Contract Manufacturing
37.6%$53M
KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
IMVTImmunovant, Inc.

Segment breakdown not available.

RCUSArcus Biosciences, Inc.
FY 2025
License And Development Services
87.4%$221M
Development Services
6.7%$17M
R&D Services
3.2%$8M
License
2.8%$7M

PYXS vs MGNX vs KO vs IMVT vs RCUS — Financial Metrics

Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLKOLAGGINGRCUS

Income & Cash Flow (Last 12 Months)

KO leads this category, winning 4 of 6 comparable metrics.

KO and IMVT operate at a comparable scale, with $49.3B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to PYXS's -5.9%. On growth, MGNX holds the edge at +57.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricPYXS logoPYXSPyxis Oncology, I…MGNX logoMGNXMacroGenics, Inc.KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…
RevenueTrailing 12 months$14M$157M$49.3B$0$236M
EBITDAEarnings before interest/tax-$81M-$57M$15.5B-$532M-$391M
Net IncomeAfter-tax profit-$82M-$70M$13.7B-$506M-$369M
Free Cash FlowCash after capex-$67M-$72M$12.6B-$407M-$489M
Gross MarginGross profit ÷ Revenue+99.8%+69.9%+61.7%+90.7%
Operating MarginEBIT ÷ Revenue-6.2%-40.5%+29.3%-168.6%
Net MarginNet income ÷ Revenue-5.9%-44.8%+27.8%-156.4%
FCF MarginFCF ÷ Revenue-4.8%-45.6%+25.5%-2.1%
Rev. Growth (YoY)Latest quarter vs prior year+57.5%+12.1%-39.3%
EPS Growth (YoY)Latest quarter vs prior year-5.7%+10.8%+18.2%-14.1%+10.5%
KO leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

Evenly matched — PYXS and MGNX and IMVT each lead in 1 of 3 comparable metrics.
MetricPYXS logoPYXSPyxis Oncology, I…MGNX logoMGNXMacroGenics, Inc.KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…
Market CapShares × price$106M$255M$355.2B$6.8B$2.3B
Enterprise ValueMkt cap + debt − cash$109M$304M$390.4B$5.8B$2.2B
Trailing P/EPrice ÷ TTM EPS-1.30x-3.40x27.15x-11.87x-7.08x
Forward P/EPrice ÷ next-FY EPS est.25.24x
PEG RatioP/E ÷ EPS growth rate2.43x
EV / EBITDAEnterprise value multiple26.36x
Price / SalesMarket cap ÷ Revenue7.63x1.70x7.41x9.50x
Price / BookPrice ÷ Book value/share1.94x4.56x10.39x7.04x3.97x
Price / FCFMarket cap ÷ FCF67.07x
Evenly matched — PYXS and MGNX and IMVT each lead in 1 of 3 comparable metrics.

Profitability & Efficiency

KO leads this category, winning 6 of 9 comparable metrics.

KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-148 for MGNX. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to MGNX's 1.92x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs RCUS's 0/9, reflecting strong financial health.

MetricPYXS logoPYXSPyxis Oncology, I…MGNX logoMGNXMacroGenics, Inc.KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…
ROE (TTM)Return on equity-135.6%-147.8%+41.1%-68.2%-69.0%
ROA (TTM)Return on assets-85.0%-28.4%+13.1%-62.2%-35.3%
ROICReturn on invested capital-71.1%-144.1%+15.8%-64.1%
ROCEReturn on capital employed-80.4%-34.7%+17.3%-68.3%-42.1%
Piotroski ScoreFundamental quality 0–922720
Debt / EquityFinancial leverage0.35x1.92x1.33x0.00x0.16x
Net DebtTotal debt minus cash$3M$50M$35.2B-$902M-$123M
Cash & Equiv.Liquid assets$15M$57M$10.3B$902M$222M
Total DebtShort + long-term debt$19M$107M$45.5B$72,000$99M
Interest CoverageEBIT ÷ Interest expense-4.78x10.70x-13.38x
KO leads this category, winning 6 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

IMVT leads this category, winning 4 of 6 comparable metrics.

A $10,000 investment in IMVT five years ago would be worth $30,700 today (with dividends reinvested), compared to $1,265 for PYXS. Over the past 12 months, RCUS leads with a +156.6% total return vs KO's +17.4%. The 3-year compound annual growth rate (CAGR) favors IMVT at 14.9% vs PYXS's -17.9% — a key indicator of consistent wealth creation.

MetricPYXS logoPYXSPyxis Oncology, I…MGNX logoMGNXMacroGenics, Inc.KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…
YTD ReturnYear-to-date+45.2%+149.1%+20.2%+26.9%+0.0%
1-Year ReturnPast 12 months+30.5%+134.5%+17.4%+103.6%+156.6%
3-Year ReturnCumulative with dividends-44.7%-30.6%+46.9%+51.6%+15.9%
5-Year ReturnCumulative with dividends-87.3%-81.2%+63.6%+207.0%-6.4%
10-Year ReturnCumulative with dividends-87.3%-84.8%+120.9%+230.5%+37.1%
CAGR (3Y)Annualised 3-year return-17.9%-11.5%+13.7%+14.9%+5.0%
IMVT leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.15 beta — it tends to amplify market swings less than RCUS's 1.98 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.2% from its 52-week high vs PYXS's 30.1% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricPYXS logoPYXSPyxis Oncology, I…MGNX logoMGNXMacroGenics, Inc.KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…
Beta (5Y)Sensitivity to S&P 5001.50x1.59x-0.15x1.67x1.98x
52-Week HighHighest price in past year$5.55$4.64$84.04$36.27$28.72
52-Week LowLowest price in past year$0.97$1.19$65.35$14.32$7.91
% of 52W HighCurrent price vs 52-week peak+30.1%+86.4%+98.2%+90.6%+81.1%
RSI (14)Momentum oscillator 0–10042.049.165.751.939.3
Avg Volume (50D)Average daily shares traded528K1.0M12.6M1.9M1.1M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: PYXS as "Buy", MGNX as "Buy", KO as "Buy", IMVT as "Buy", RCUS as "Buy". Consensus price targets imply 229.3% upside for PYXS (target: $6) vs 4.6% for KO (target: $86). KO is the only dividend payer here at 2.47% yield — a key consideration for income-focused portfolios.

MetricPYXS logoPYXSPyxis Oncology, I…MGNX logoMGNXMacroGenics, Inc.KO logoKOThe Coca-Cola Com…IMVT logoIMVTImmunovant, Inc.RCUS logoRCUSArcus Biosciences…
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$5.50$6.00$86.29$43.67$31.17
# AnalystsCovering analysts922482318
Dividend YieldAnnual dividend ÷ price+2.5%
Dividend StreakConsecutive years of raises56
Dividend / ShareAnnual DPS$2.04
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+0.2%0.0%0.0%
Insufficient data to determine a leader in this category.
Key Takeaway

KO leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). IMVT leads in 1 (Total Returns). 1 tied.

Best OverallThe Coca-Cola Company (KO)Leads 3 of 6 categories
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PYXS vs MGNX vs KO vs IMVT vs RCUS: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is PYXS or MGNX or KO or IMVT or RCUS a better buy right now?

For growth investors, The Coca-Cola Company (KO) is the stronger pick with 1.

9% revenue growth year-over-year, versus -14. 2% for Pyxis Oncology, Inc. (PYXS). The Coca-Cola Company (KO) offers the better valuation at 27. 1x trailing P/E (25. 2x forward), making it the more compelling value choice. Analysts rate Pyxis Oncology, Inc. (PYXS) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — PYXS or MGNX or KO or IMVT or RCUS?

Over the past 5 years, Immunovant, Inc.

(IMVT) delivered a total return of +207. 0%, compared to -87. 3% for Pyxis Oncology, Inc. (PYXS). Over 10 years, the gap is even starker: IMVT returned +230. 5% versus PYXS's -87. 3%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — PYXS or MGNX or KO or IMVT or RCUS?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

15β versus Arcus Biosciences, Inc. 's 1. 98β — meaning RCUS is approximately -1437% more volatile than KO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 192% for MacroGenics, Inc. — giving it more financial flexibility in a downturn.

04

Which is growing faster — PYXS or MGNX or KO or IMVT or RCUS?

By revenue growth (latest reported year), The Coca-Cola Company (KO) is pulling ahead at 1.

9% versus -14. 2% for Pyxis Oncology, Inc. (PYXS). On earnings-per-share growth, the picture is similar: The Coca-Cola Company grew EPS 23. 6% year-over-year, compared to -10. 3% for MacroGenics, Inc.. Over a 3-year CAGR, RCUS leads at 30. 2% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — PYXS or MGNX or KO or IMVT or RCUS?

The Coca-Cola Company (KO) is the more profitable company, earning 27.

3% net margin versus -574. 5% for Pyxis Oncology, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -609. 2% for PYXS. At the gross margin level — before operating expenses — RCUS leads at 96. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is PYXS or MGNX or KO or IMVT or RCUS more undervalued right now?

Analyst consensus price targets imply the most upside for PYXS: 229.

3% to $5. 50.

07

Which pays a better dividend — PYXS or MGNX or KO or IMVT or RCUS?

In this comparison, KO (2.

5% yield) pays a dividend. PYXS, MGNX, IMVT, RCUS do not pay a meaningful dividend and should not be held primarily for income.

08

Is PYXS or MGNX or KO or IMVT or RCUS better for a retirement portfolio?

For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.

15), 2. 5% yield, +120. 9% 10Y return). Arcus Biosciences, Inc. (RCUS) carries a higher beta of 1. 98 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +120. 9%, RCUS: +37. 1%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between PYXS and MGNX and KO and IMVT and RCUS?

These companies operate in different sectors (PYXS (Healthcare) and MGNX (Healthcare) and KO (Consumer Defensive) and IMVT (Healthcare) and RCUS (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

KO pays a dividend while PYXS, MGNX, IMVT, RCUS do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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