Comprehensive Stock Comparison

Compare Relay Therapeutics, Inc. (RLAY) vs Apple Inc. (AAPL) Stock

Analyze side-by-side fundamentals, valuation, growth, and profitability to decide which stock is the better buy.

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Quick Verdict

CategoryWinnerWhy
GrowthRLAY53.4% revenue growth vs AAPL's 6.4%
Quality / MarginsAAPL27.0% net margin vs RLAY's -18.0%
Stability / SafetyAAPLBeta 1.28 vs RLAY's 1.70
DividendsAAPL0.4% yield; 14-year raise streak; RLAY pays no meaningful dividend
Momentum (1Y)RLAY+200.9% vs AAPL's +9.7%
Efficiency (ROA)AAPL31.1% ROA vs RLAY's -44.5%, ROIC 64.5% vs -37.3%
Bottom line: AAPL leads in 4 of 6 categories, making it the stronger pick for investors who prioritize profitability and margin quality and capital preservation and lower volatility. Relay Therapeutics, Inc. is the better choice for growth and revenue expansion and recent price momentum and sentiment. They serve different portfolio roles — they are not true substitutes.

Who Each Stock Is For

Income & stability

Growth exposure

Long-term compounding (10Y)

Sleep-well-at-night portfolio

Defensive / Recession hedge

Business Model

What each company does and how it makes money

RLAYRelay Therapeutics, Inc.
Healthcare

Relay Therapeutics is a clinical-stage biotech company developing precision medicines for cancer and genetic diseases using computational drug discovery. It generates revenue primarily through research collaborations and licensing deals — with no commercial products yet — while advancing its own pipeline of targeted oncology therapies. Its key competitive advantage is proprietary technology that analyzes protein motion to design more effective small molecule drugs, potentially accelerating and improving the drug discovery process.

AAPLApple Inc.
Technology

Apple is a technology giant that designs and sells premium consumer electronics — most famously the iPhone — along with related software and services. It generates revenue primarily from hardware sales (roughly 80% of total) and a fast-growing services segment (around 20%) that includes the App Store, subscriptions, and licensing. Its key competitive advantage is a powerful ecosystem that locks users into its hardware, software, and services through seamless integration and high switching costs.

Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

RLAYRelay Therapeutics, Inc.

Segment breakdown not available.

AAPLApple Inc.
FY 2025
iPhone
50.4%$209.6B
Service
26.2%$109.2B
Wearables, Home and Accessories
8.6%$35.7B
Mac
8.1%$33.7B
iPad
6.7%$28.0B

Financial Metrics Comparison

Side-by-side fundamentals across 2 stocks. BestLagging

Financial Scorecard

AAPL 4RLAY 1
Financial MetricsAAPL3/4 metrics
Valuation MetricsRLAY2/3 metrics
Profitability & EfficiencyAAPL5/8 metrics
Total ReturnsAAPL4/6 metrics
Risk & VolatilityAAPL2/2 metrics
Analyst Outlook0/0 metrics

AAPL leads in 4 of 6 categories (Financial Metrics, Profitability & Efficiency). RLAY leads in 1 (Valuation Metrics).

Financial Metrics (TTM)

AAPL is the larger business by revenue, generating $435.6B annually — 28369.7x RLAY's $15M. AAPL is the more profitable business, keeping 27.0% of every revenue dollar as net income compared to RLAY's -18.0%.

MetricRLAYRelay Therapeutic…AAPLApple Inc.
RevenueTrailing 12 months$15M$435.6B
EBITDAEarnings before interest/tax-$303M$152.9B
Net IncomeAfter-tax profit-$276M$117.8B
Free Cash FlowCash after capex-$236M$123.3B
Gross MarginGross profit ÷ Revenue+47.3%
Operating MarginEBIT ÷ Revenue-19.7%+32.4%
Net MarginNet income ÷ Revenue-18.0%+27.0%
FCF MarginFCF ÷ Revenue-15.4%+28.3%
Rev. Growth (YoY)Latest quarter vs prior year+15.7%
EPS Growth (YoY)Latest quarter vs prior year+31.1%+18.3%
AAPL leads this category, winning 3 of 4 comparable metrics.

Valuation Metrics

MetricRLAYRelay Therapeutic…AAPLApple Inc.
Market CapShares × price$1.8B$3.88T
Enterprise ValueMkt cap + debt − cash$1.7B$3.97T
Trailing P/EPrice ÷ TTM EPS-6.37x35.41x
Forward P/EPrice ÷ next-FY EPS est.31.15x
PEG RatioP/E ÷ EPS growth rate1.98x
EV / EBITDAEnterprise value multiple27.45x
Price / SalesMarket cap ÷ Revenue116.18x9.33x
Price / BookPrice ÷ Book value/share3.10x53.76x
Price / FCFMarket cap ÷ FCF39.33x
RLAY leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

AAPL delivers a 133.5% return on equity — every $100 of shareholder capital generates $134 in annual profit, vs $-49 for RLAY. RLAY carries lower financial leverage with a 0.06x debt-to-equity ratio, signaling a more conservative balance sheet compared to AAPL's 1.67x. On the Piotroski fundamental quality scale (0–9), AAPL scores 7/9 vs RLAY's 5/9, reflecting strong financial health.

MetricRLAYRelay Therapeutic…AAPLApple Inc.
ROE (TTM)Return on equity-48.8%+133.5%
ROA (TTM)Return on assets-44.5%+31.1%
ROICReturn on invested capital-37.3%+64.5%
ROCEReturn on capital employed-42.7%+69.6%
Piotroski ScoreFundamental quality 0–957
Debt / EquityFinancial leverage0.06x1.67x
Net DebtTotal debt minus cash-$52M$89.7B
Cash & Equiv.Liquid assets$84M$33.5B
Total DebtShort + long-term debt$32M$123.3B
Interest CoverageEBIT ÷ Interest expense
AAPL leads this category, winning 5 of 8 comparable metrics.

Total Returns (with DRIP)

A $10,000 investment in AAPL five years ago would be worth $21,049 today (with dividends reinvested), compared to $2,553 for RLAY. Over the past 12 months, RLAY leads with a +200.9% total return vs AAPL's +9.7%. The 3-year compound annual growth rate (CAGR) favors AAPL at 21.9% vs RLAY's -14.0% — a key indicator of consistent wealth creation.

MetricRLAYRelay Therapeutic…AAPLApple Inc.
YTD ReturnYear-to-date+25.4%-2.4%
1-Year ReturnPast 12 months+200.9%+9.7%
3-Year ReturnCumulative with dividends-36.5%+81.2%
5-Year ReturnCumulative with dividends-74.5%+110.5%
10-Year ReturnCumulative with dividends-70.7%+1027.4%
CAGR (3Y)Annualised 3-year return-14.0%+21.9%
AAPL leads this category, winning 4 of 6 comparable metrics.

Risk & Volatility

AAPL is the less volatile stock with a 1.28 beta — it tends to amplify market swings less than RLAY's 1.70 beta. A beta below 1.0 means the stock typically moves less than the S&P 500.

MetricRLAYRelay Therapeutic…AAPLApple Inc.
Beta (5Y)Sensitivity to S&P 5001.70x1.28x
52-Week HighHighest price in past year$11.43$288.61
52-Week LowLowest price in past year$1.78$169.21
% of 52W HighCurrent price vs 52-week peak+89.8%+91.5%
RSI (14)Momentum oscillator 0–10059.357.5
Avg Volume (50D)Average daily shares traded1.9M40.9M
AAPL leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Wall Street rates RLAY as "Buy" and AAPL as "Buy". Consensus price targets imply 31.6% upside for RLAY (target: $14) vs 14.7% for AAPL (target: $303). AAPL is the only dividend payer here at 0.39% yield — a key consideration for income-focused portfolios.

MetricRLAYRelay Therapeutic…AAPLApple Inc.
Analyst RatingConsensus buy/hold/sellBuyBuy
Price TargetConsensus 12-month target$13.50$303.11
# AnalystsCovering analysts14109
Dividend YieldAnnual dividend ÷ price+0.4%
Dividend StreakConsecutive years of raises14
Dividend / ShareAnnual DPS$1.03
Buyback YieldShare repurchases ÷ mkt cap+0.1%+2.3%
Insufficient data to determine a leader in this category.

Historical Charts

Charts are rendered on first load. Hover for details.

Chart 1Total Return — 5 Years (Rebased to 100)

StockJul 20Feb 26Change
Relay Therapeutics,… (RLAY)10023.25-76.7%
Apple Inc. (AAPL)100247.85+147.9%

Apple Inc. (AAPL) returned +110% over 5 years vs Relay Therapeutics,… (RLAY)'s -74%. A $10,000 investment in AAPL 5 years ago would be worth $21,049 today (including dividends reinvested).

Chart 2Revenue Growth — 10 Years

Stock20162025Change
Relay Therapeutics,… (RLAY)$0.00$15M
Apple Inc. (AAPL)$215.6B$416.2B+93.0%

Apple Inc.'s revenue grew from $215.6B (2016) to $416.2B (2025) — a 7.6% CAGR.

Chart 3Net Margin Trend — 10 Years

Stock20162025Change
Relay Therapeutics,… (RLAY)-63.4%-18.0%+71.6%
Apple Inc. (AAPL)21.2%26.9%+27.0%

Apple Inc.'s net margin went from 21% (2016) to 27% (2025).

Chart 4P/E Ratio History — 9 Years

Stock20172025Change
Apple Inc. (AAPL)18.436.4+97.8%

Apple Inc. has traded in a 13x–41x P/E range over 9 years; current trailing P/E is ~35x.

Chart 5EPS Growth — 10 Years

Stock20162025Change
Relay Therapeutics,… (RLAY)-19.63-1.61+91.8%
Apple Inc. (AAPL)2.087.46+258.7%

Apple Inc.'s EPS grew from $2.08 (2016) to $7.46 (2025) — a 15% CAGR.

Chart 6Free Cash Flow — 5 Years

2021
$-78M
$93B
2022
$-239M
$111B
2023
$-304M
$100B
2024
$-251M
$109B
2025
$-236M
$99B
Relay Therapeutics,… (RLAY)Apple Inc. (AAPL)

Relay Therapeutics, Inc. generated $-236M FCF in 2025 (-203% vs 2021). Apple Inc. generated $99B FCF in 2025 (+6% vs 2021).

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RLAY vs AAPL: Frequently Asked Questions

8 questions · data-driven answers · updated daily

01

Is RLAY or AAPL a better buy right now?

Apple Inc. (AAPL) offers the better valuation at 35.4x trailing P/E (31.1x forward), making it the more compelling value choice. Analysts rate Relay Therapeutics, Inc. (RLAY) a "Buy" — based on 14 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — RLAY or AAPL?

Over the past 5 years, Apple Inc. (AAPL) delivered a total return of +110.5%, compared to -74.5% for Relay Therapeutics, Inc. (RLAY). A $10,000 investment in AAPL five years ago would be worth approximately $21K today (assuming dividends reinvested). Over 10 years, the gap is even starker: AAPL returned +1027% versus RLAY's -70.7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — RLAY or AAPL?

By beta (market sensitivity over 5 years), Apple Inc. (AAPL) is the lower-risk stock at 1.28β versus Relay Therapeutics, Inc.'s 1.70β — meaning RLAY is approximately 33% more volatile than AAPL relative to the S&P 500. On balance sheet safety, Relay Therapeutics, Inc. (RLAY) carries a lower debt/equity ratio of 6% versus 167% for Apple Inc. — giving it more financial flexibility in a downturn.

04

Which has better profit margins — RLAY or AAPL?

Apple Inc. (AAPL) is the more profitable company, earning 26.9% net margin versus -1800.6% for Relay Therapeutics, Inc. — meaning it keeps 26.9% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: AAPL leads at 32.0% versus -1971.6% for RLAY. At the gross margin level — before operating expenses — AAPL leads at 46.9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

05

Is RLAY or AAPL more undervalued right now?

Analyst consensus price targets imply the most upside for RLAY: 31.6% to $13.50.

06

Which pays a better dividend — RLAY or AAPL?

In this comparison, AAPL (0.4% yield) pays a dividend. RLAY does not pay a meaningful dividend and should not be held primarily for income.

07

Is RLAY or AAPL better for a retirement portfolio?

For long-horizon retirement investors, Apple Inc. (AAPL) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 1.28), +1027% 10Y return). Relay Therapeutics, Inc. (RLAY) carries a higher beta of 1.70 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (AAPL: +1027%, RLAY: -70.7%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

08

What are the main differences between RLAY and AAPL?

These companies operate in different sectors (RLAY (Healthcare) and AAPL (Technology)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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