Biotechnology
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Side-by-side financial analysisStock Comparison
TBPH vs INVA vs PRGO vs SUPN vs PCRX vs KO vs JPM
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
Drug Manufacturers - Specialty & Generic
Beverages - Non-Alcoholic
Banks - Diversified
TBPH vs INVA vs PRGO vs SUPN vs PCRX vs KO vs JPM — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||||
|---|---|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Drug Manufacturers - Specialty & Generic | Beverages - Non-Alcoholic | Banks - Diversified |
| Market Cap | $855M | $1.66B | $1.42B | $2.56B | $878M | $341.71B | $908.57B |
| Revenue (TTM) | $110M | $424M | $4.18B | $777M | $735M | $49.28B | $280.33B |
| Net Income (TTM) | $115M | $504M | $-1.82B | $-29M | $9M | $13.70B | $57.05B |
| Gross Margin | 80.4% | 76.2% | 34.2% | 89.4% | 60.2% | 61.7% | 60.0% |
| Operating Margin | 0.1% | 14.8% | -4.1% | -5.5% | 3.4% | 29.3% | 25.9% |
| Forward P/E | 7.0x | 6.3x | 4.8x | 17.8x | 7.8x | 24.3x | 14.6x |
| Total Debt | $75M | $269M | $3.97B | $41M | $454M | $45.49B | $942.38B |
| Cash & Equiv. | $168M | $551M | $532M | $128M | $159M | $10.27B | $343.34B |
TBPH vs INVA vs PRGO vs SUPN vs PCRX vs KO vs JPM — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 20 | Jun 26 | Return |
|---|---|---|---|
| Theravance Biopharm… (TBPH) | 100 | 79.0 | -21.0% |
| Innoviva, Inc. (INVA) | 100 | 160.9 | +60.9% |
| Perrigo Company plc (PRGO) | 100 | 18.5 | -81.5% |
| Supernus Pharmaceut… (SUPN) | 100 | 186.9 | +86.9% |
| Pacira BioSciences,… (PCRX) | 100 | 42.6 | -57.4% |
| The Coca-Cola Compa… (KO) | 100 | 177.7 | +77.7% |
| JPMorgan Chase & Co. (JPM) | 100 | 345.8 | +245.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: TBPH vs INVA vs PRGO vs SUPN vs PCRX vs KO vs JPM
Each card shows where this stock fits in a portfolio — not just who wins on paper.
TBPH is the #2 pick in this set and the best alternative if growth exposure is your priority.
- Rev growth 66.9%, EPS growth 279.1%, 3Y rev CAGR 27.9%
- 66.9% revenue growth vs PRGO's -2.8%
- +56.1% vs PRGO's -56.6%
INVA carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and valuation efficiency.
- Lower volatility, beta 0.03, Low D/E 22.9%, current ratio 14.64x
- PEG 0.61 vs KO's 2.17
- Beta 0.03, current ratio 14.64x
- Lower P/E (6.3x vs 14.6x), PEG 0.61 vs 0.83
- 118.9% margin vs PRGO's -43.5%
PRGO ranks third and is worth considering specifically for income & stability.
- Dividend streak 23 yrs, beta 1.11, yield 11.2%
- 11.2% yield, 23-year raise streak, vs KO's 2.6%, (4 stocks pay no dividend)
SUPN lags the leaders in this set but could rank higher in a more targeted comparison.
Among these 7 stocks, PCRX doesn't own a clear edge in any measured category.
KO doesn't hold a clear category lead here; it's more of a secondary option in this specific comparison.
JPM is the clearest fit if your priority is long-term compounding.
- 481.2% 10Y total return vs SUPN's 142.4%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 66.9% revenue growth vs PRGO's -2.8% | |
| Value | Lower P/E (6.3x vs 14.6x), PEG 0.61 vs 0.83 | |
| Quality / Margins | 118.9% margin vs PRGO's -43.5% | |
| Stability / Safety | Beta 0.03 vs PRGO's 1.11, lower leverage | |
| Dividends | 11.2% yield, 23-year raise streak, vs KO's 2.6%, (4 stocks pay no dividend) | |
| Momentum (1Y) | +56.1% vs PRGO's -56.6% | |
| Efficiency (ROA) | 32.4% ROA vs PRGO's -19.8%, ROIC 14.2% vs 3.7% |
TBPH vs INVA vs PRGO vs SUPN vs PCRX vs KO vs JPM — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
TBPH vs INVA vs PRGO vs SUPN vs PCRX vs KO vs JPM — Financial Metrics
Side-by-side numbers across 7 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
PRGO leads in 1 of 6 categories
INVA leads 1 • JPM leads 1 • TBPH leads 0 • SUPN leads 0 • PCRX leads 0 • KO leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — INVA and SUPN each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JPM is the larger business by revenue, generating $280.3B annually — 2553.7x TBPH's $110M. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to PRGO's -43.5%. On growth, SUPN holds the edge at +38.6% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| RevenueTrailing 12 months | $110M | $424M | $4.2B | $777M | $735M | $49.3B | $280.3B |
| EBITDAEarnings before interest/tax | $4M | $86M | $58M | $29M | $95M | $15.5B | $81.4B |
| Net IncomeAfter-tax profit | $115M | $504M | -$1.8B | -$29M | $9M | $13.7B | $57.0B |
| Free Cash FlowCash after capex | $269M | $181M | $108M | $82M | $133M | $12.6B | $100.9B |
| Gross MarginGross profit ÷ Revenue | +80.4% | +76.2% | +34.2% | +89.4% | +60.2% | +61.7% | +60.0% |
| Operating MarginEBIT ÷ Revenue | +0.1% | +14.8% | -4.1% | -5.5% | +3.4% | +29.3% | +25.9% |
| Net MarginNet income ÷ Revenue | +104.3% | +118.9% | -43.5% | -3.7% | +1.3% | +27.8% | +20.4% |
| FCF MarginFCF ÷ Revenue | +2.4% | +42.6% | +2.6% | +10.6% | +18.1% | +25.5% | +36.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | +15.0% | +10.6% | -7.2% | +38.6% | +5.0% | +12.1% | — |
| EPS Growth (YoY)Latest quarter vs prior year | +64.4% | +4.0% | -56.4% | +81.0% | -30.0% | +18.2% | +16.0% |
Valuation Metrics
PRGO leads this category, winning 3 of 7 comparable metrics.
Valuation Metrics
At 6.8x trailing earnings, INVA trades at a 95% valuation discount to PCRX's 139.6x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.66x vs KO's 2.34x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Market CapShares × price | $855M | $1.7B | $1.4B | $2.6B | $878M | $341.7B | $908.6B |
| Enterprise ValueMkt cap + debt − cash | $762M | $1.4B | $4.9B | $2.5B | $1.2B | $376.9B | $1.51T |
| Trailing P/EPrice ÷ TTM EPS | 8.05x | 6.82x | -1.00x | -65.26x | 139.56x | 26.12x | 16.22x |
| Forward P/EPrice ÷ next-FY EPS est. | 7.05x | 6.29x | 4.84x | 17.85x | 7.76x | 24.27x | 14.60x |
| PEG RatioP/E ÷ EPS growth rate | — | 0.66x | — | — | — | 2.34x | 0.92x |
| EV / EBITDAEnterprise value multiple | — | 6.76x | 7.13x | 45.12x | 9.44x | 25.45x | 18.52x |
| Price / SalesMarket cap ÷ Revenue | 7.95x | 3.90x | 0.33x | 3.55x | 1.21x | 7.13x | 3.25x |
| Price / BookPrice ÷ Book value/share | 2.88x | 1.63x | 0.48x | 2.36x | 1.45x | 9.99x | 2.51x |
| Price / FCFMarket cap ÷ FCF | 3.58x | 8.48x | 9.77x | 55.56x | 6.43x | 64.52x | 9.01x |
Profitability & Efficiency
INVA leads this category, winning 4 of 9 comparable metrics.
Profitability & Efficiency
INVA delivers a 47.6% return on equity — every $100 of shareholder capital generates $48 in annual profit, vs $-51 for PRGO. SUPN carries lower financial leverage with a 0.04x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), PCRX scores 9/9 vs SUPN's 4/9, reflecting strong financial health.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| ROE (TTM)Return on equity | +43.8% | +47.6% | -50.7% | -2.7% | +1.3% | +41.1% | +15.9% |
| ROA (TTM)Return on assets | +25.5% | +32.4% | -19.8% | -2.0% | +0.7% | +13.1% | +1.3% |
| ROICReturn on invested capital | -5.1% | +14.2% | +3.7% | -2.8% | +2.3% | +15.8% | +4.5% |
| ROCEReturn on capital employed | -3.4% | +12.4% | +4.3% | -3.4% | +2.8% | +17.3% | +8.9% |
| Piotroski ScoreFundamental quality 0–9 | 6 | 5 | 4 | 4 | 9 | 7 | 5 |
| Debt / EquityFinancial leverage | 0.25x | 0.23x | 1.35x | 0.04x | 0.66x | 1.33x | 2.60x |
| Net DebtTotal debt minus cash | -$92M | -$282M | $3.4B | -$87M | $296M | $35.2B | $599.0B |
| Cash & Equiv.Liquid assets | $168M | $551M | $532M | $128M | $159M | $10.3B | $343.3B |
| Total DebtShort + long-term debt | $75M | $269M | $4.0B | $41M | $454M | $45.5B | $942.4B |
| Interest CoverageEBIT ÷ Interest expense | 2.32x | 63.45x | -7.20x | — | 2.37x | 10.70x | 0.74x |
Total Returns (Dividends Reinvested)
JPM leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in JPM five years ago would be worth $23,548 today (with dividends reinvested), compared to $3,394 for PRGO. Over the past 12 months, TBPH leads with a +56.1% total return vs PRGO's -56.6%. The 3-year compound annual growth rate (CAGR) favors JPM at 33.7% vs PRGO's -26.2% — a key indicator of consistent wealth creation.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| YTD ReturnYear-to-date | -8.7% | +13.2% | -22.0% | -10.3% | -8.7% | +16.4% | +0.8% |
| 1-Year ReturnPast 12 months | +56.1% | +4.8% | -56.6% | +34.6% | -7.5% | +17.7% | +20.9% |
| 3-Year ReturnCumulative with dividends | +57.8% | +75.4% | -59.8% | +32.3% | -45.4% | +39.3% | +138.8% |
| 5-Year ReturnCumulative with dividends | -5.4% | +68.7% | -66.1% | +38.3% | -62.6% | +65.3% | +135.5% |
| 10-Year ReturnCumulative with dividends | -27.5% | +101.2% | -79.7% | +142.4% | -41.8% | +115.0% | +481.2% |
| CAGR (3Y)Annualised 3-year return | +16.4% | +20.6% | -26.2% | +9.8% | -18.3% | +11.7% | +33.7% |
Risk & Volatility
Evenly matched — KO and JPM each lead in 1 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.23 beta — it tends to amplify market swings less than PRGO's 1.11 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. JPM currently trades 96.2% from its 52-week high vs PRGO's 36.0% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.78x | 0.03x | 1.11x | 0.73x | 0.43x | -0.23x | 0.87x |
| 52-Week HighHighest price in past year | $21.03 | $25.15 | $28.44 | $59.68 | $27.64 | $84.04 | $338.09 |
| 52-Week LowLowest price in past year | $10.44 | $16.52 | $9.23 | $30.83 | $18.80 | $65.35 | $269.72 |
| % of 52W HighCurrent price vs 52-week peak | +78.8% | +89.4% | +36.0% | +74.4% | +80.8% | +94.5% | +96.2% |
| RSI (14)Momentum oscillator 0–100 | 56.6 | 52.6 | 38.6 | 34.7 | 43.7 | 49.2 | 72.1 |
| Avg Volume (50D)Average daily shares traded | 344K | 677K | 2.5M | 598K | 454K | 13.6M | 7.4M |
Analyst Outlook
Evenly matched — PRGO and KO each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: TBPH as "Hold", INVA as "Buy", PRGO as "Hold", SUPN as "Buy", PCRX as "Hold", KO as "Buy", JPM as "Buy". Consensus price targets imply 253.2% upside for PRGO (target: $36) vs -15.6% for TBPH (target: $14). For income investors, PRGO offers the higher dividend yield at 11.22% vs JPM's 1.83%.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Hold | Buy | Hold | Buy | Buy |
| Price TargetConsensus 12-month target | $14.00 | $37.00 | $36.20 | $60.00 | $32.00 | $86.13 | $339.75 |
| # AnalystsCovering analysts | 16 | 10 | 36 | 14 | 36 | 48 | 61 |
| Dividend YieldAnnual dividend ÷ price | — | — | +11.2% | — | — | +2.6% | +1.8% |
| Dividend StreakConsecutive years of raises | — | 2 | 23 | — | — | 56 | 15 |
| Dividend / ShareAnnual DPS | — | — | $1.15 | — | — | $2.04 | $5.95 |
| Buyback YieldShare repurchases ÷ mkt cap | +0.5% | +0.3% | 0.0% | 0.0% | +16.9% | +0.2% | +3.8% |
PRGO leads in 1 of 6 categories (Valuation Metrics). INVA leads in 1 (Profitability & Efficiency). 3 tied.
TBPH vs INVA vs PRGO vs SUPN vs PCRX vs KO vs JPM: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM a better buy right now?
For growth investors, Theravance Biopharma, Inc.
(TBPH) is the stronger pick with 66. 9% revenue growth year-over-year, versus -2. 8% for Perrigo Company plc (PRGO). Innoviva, Inc. (INVA) offers the better valuation at 6. 8x trailing P/E (6. 3x forward), making it the more compelling value choice. Analysts rate Innoviva, Inc. (INVA) a "Buy" — based on 10 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 8x versus Pacira BioSciences, Inc. at 139. 6x. On forward P/E, Perrigo Company plc is actually cheaper at 4. 8x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Innoviva, Inc. wins at 0. 61x versus The Coca-Cola Company's 2. 17x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM?
Over the past 5 years, JPMorgan Chase & Co.
(JPM) delivered a total return of +135. 5%, compared to -66. 1% for Perrigo Company plc (PRGO). Over 10 years, the gap is even starker: JPM returned +481. 2% versus PRGO's -79. 7%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
23β versus Perrigo Company plc's 1. 11β — meaning PRGO is approximately -577% more volatile than KO relative to the S&P 500. On balance sheet safety, Supernus Pharmaceuticals, Inc. (SUPN) carries a lower debt/equity ratio of 4% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM?
By revenue growth (latest reported year), Theravance Biopharma, Inc.
(TBPH) is pulling ahead at 66. 9% versus -2. 8% for Perrigo Company plc (PRGO). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -723. 2% for Perrigo Company plc. Over a 3-year CAGR, TBPH leads at 27. 9% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM?
Theravance Biopharma, Inc.
(TBPH) is the more profitable company, earning 98. 5% net margin versus -33. 5% for Perrigo Company plc — meaning it keeps 98. 5% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -12. 3% for TBPH. At the gross margin level — before operating expenses — TBPH leads at 94. 9%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Innoviva, Inc. (INVA) is the more undervalued stock at a PEG of 0. 61x versus The Coca-Cola Company's 2. 17x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Perrigo Company plc (PRGO) trades at 4. 8x forward P/E versus 24. 3x for The Coca-Cola Company — 19. 4x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for PRGO: 253. 2% to $36. 20.
08Which pays a better dividend — TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM?
In this comparison, PRGO (11.
2% yield), KO (2. 6% yield), JPM (1. 8% yield) pay a dividend. TBPH, INVA, SUPN, PCRX do not pay a meaningful dividend and should not be held primarily for income.
09Is TBPH or INVA or PRGO or SUPN or PCRX or KO or JPM better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
23), 2. 6% yield, +115. 0% 10Y return). Both have compounded well over 10 years (KO: +115. 0%, TBPH: -27. 5%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between TBPH and INVA and PRGO and SUPN and PCRX and KO and JPM?
These companies operate in different sectors (TBPH (Healthcare) and INVA (Healthcare) and PRGO (Healthcare) and SUPN (Healthcare) and PCRX (Healthcare) and KO (Consumer Defensive) and JPM (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: TBPH is a small-cap high-growth stock; INVA is a small-cap high-growth stock; PRGO is a small-cap income-oriented stock; SUPN is a small-cap quality compounder stock; PCRX is a small-cap quality compounder stock; KO is a large-cap quality compounder stock; JPM is a large-cap deep-value stock. PRGO, KO, JPM pay a dividend while TBPH, INVA, SUPN, PCRX do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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