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ZVSA
LLY logo
LLY
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KO logo
KO
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Stock Comparison

ZVSA vs LLY vs CRL vs NVO vs KO vs JPM

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
ZVSA
ZyVersa Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.58B
5Y Perf.-100.0%
LLY
Eli Lilly and Company

Drug Manufacturers - General

HealthcareNYSE • US
Market Cap$1.07T
5Y Perf.+353.3%
CRL
Charles River Laboratories International, Inc.

Medical - Diagnostics & Research

HealthcareNYSE • US
Market Cap$9.03B
5Y Perf.-35.6%
NVO
Novo Nordisk A/S

Drug Manufacturers - General

HealthcareNYSE • DK
Market Cap$194.99B
5Y Perf.-14.8%
KO
The Coca-Cola Company

Beverages - Non-Alcoholic

Consumer DefensiveNYSE • US
Market Cap$355.61B
5Y Perf.+32.7%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$896.00B
5Y Perf.+126.2%

ZVSA vs LLY vs CRL vs NVO vs KO vs JPM — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
ZVSA logoZVSA
LLY logoLLY
CRL logoCRL
NVO logoNVO
KO logoKO
JPM logoJPM
IndustryBiotechnologyDrug Manufacturers - GeneralMedical - Diagnostics & ResearchDrug Manufacturers - GeneralBeverages - Non-AlcoholicBanks - Diversified
Market Cap$1.58B$1.07T$9.03B$194.99B$355.61B$896.00B
Revenue (TTM)$0.00$72.25B$4.03B$327.80B$49.28B$280.33B
Net Income (TTM)$-1.82B$25.27B$-185M$121.96B$13.70B$57.05B
Gross Margin83.5%31.9%81.8%61.7%60.0%
Operating Margin45.9%11.8%45.3%29.3%25.9%
Forward P/E30.9x16.9x2.0x25.3x14.4x
Total Debt$0.00$42.50B$3.07B$130.96B$45.49B$942.38B
Cash & Equiv.$102M$7.16B$214M$26.46B$10.27B$343.34B

ZVSA vs LLY vs CRL vs NVO vs KO vs JPMLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

ZVSA
LLY
CRL
NVO
KO
JPM
StockFeb 22Jun 26Return
ZyVersa Therapeutic… (ZVSA)1000.0-100.0%
Eli Lilly and Compa… (LLY)100453.3+353.3%
Charles River Labor… (CRL)10064.4-35.6%
Novo Nordisk A/S (NVO)10085.2-14.8%
The Coca-Cola Compa… (KO)100132.7+32.7%
JPMorgan Chase & Co. (JPM)100226.2+126.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: ZVSA vs LLY vs CRL vs NVO vs KO vs JPM

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: NVO leads in 4 of 7 categories (6-stock set), making it the strongest pick for valuation and capital efficiency and profitability and margin quality. Eli Lilly and Company is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. ZVSA also leads in specific categories worth noting. This set spans 3 sectors — these stocks serve different portfolio roles, not just different price points.
🥇NVO emerged as the overall leader. Track its performance:
ZVSA
ZyVersa Therapeutics, Inc.
The Defensive Choice

ZVSA ranks third and is worth considering specifically for stability.

  • Beta 0.29 vs NVO's 1.47
Best for: stability
LLY
Eli Lilly and Company
The Growth Play

LLY is the #2 pick in this set and the best alternative if growth exposure and long-term compounding is your priority.

  • Rev growth 44.7%, EPS growth 96.0%, 3Y rev CAGR 31.7%
  • 14.8% 10Y total return vs JPM's 465.8%
  • Lower volatility, beta 0.53, current ratio 1.58x
  • Beta 0.53, yield 0.5%, current ratio 1.58x
Best for: growth exposure and long-term compounding
CRL
Charles River Laboratories International, Inc.
The Healthcare Pick

CRL lags the leaders in this set but could rank higher in a more targeted comparison.

Best for: healthcare exposure
NVO
Novo Nordisk A/S
The Value Pick

NVO carries the broadest edge in this set and is the clearest fit for valuation efficiency.

  • PEG 0.10 vs KO's 2.26
  • Lower P/E (2.0x vs 25.3x), PEG 0.10 vs 2.26
  • 37.2% margin vs CRL's -4.6%
  • 4.1% yield, 1-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend)
Best for: valuation efficiency
KO
The Coca-Cola Company
The Income Angle

Among these 6 stocks, KO doesn't own a clear edge in any measured category.

Best for: consumer defensive exposure
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM is the clearest fit if your priority is income & stability.

  • Dividend streak 15 yrs, beta 0.94, yield 1.9%
Best for: income & stability
See the full category breakdown
CategoryWinnerWhy
GrowthLLY logoLLY44.7% revenue growth vs ZVSA's -100.0%
ValueNVO logoNVOLower P/E (2.0x vs 25.3x), PEG 0.10 vs 2.26
Quality / MarginsNVO logoNVO37.2% margin vs CRL's -4.6%
Stability / SafetyZVSA logoZVSABeta 0.29 vs NVO's 1.47
DividendsNVO logoNVO4.1% yield, 1-year raise streak, vs KO's 2.5%, (2 stocks pay no dividend)
Momentum (1Y)LLY logoLLY+40.3% vs ZVSA's -73.2%
Efficiency (ROA)NVO logoNVO23.3% ROA vs ZVSA's -6.5%

ZVSA vs LLY vs CRL vs NVO vs KO vs JPM — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

Discover the Biotech & Healthcare Stocks Theme

These companies are key players in the Biotech & Healthcare Stocks ecosystem. See how they stack up against the rest of the sector.

Explore Theme
ZVSAZyVersa Therapeutics, Inc.

Segment breakdown not available.

LLYEli Lilly and Company
FY 2025
Product
93.5%$61.0B
Collaboration and Other Revenue
6.5%$4.2B
CRLCharles River Laboratories International, Inc.
FY 2025
Discovery and Safety Assessment
59.8%$2.4B
Research Models and Services
21.1%$846M
Manufacturing Support
19.1%$766M
NVONovo Nordisk A/S

Segment breakdown not available.

KOThe Coca-Cola Company
FY 2025
Pacific
84.6%$31.6B
Bottling investments
15.4%$5.7B
JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000

ZVSA vs LLY vs CRL vs NVO vs KO vs JPM — Financial Metrics

Side-by-side numbers across 6 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLLLYLAGGINGJPM

Income & Cash Flow (Last 12 Months)

LLY leads this category, winning 4 of 6 comparable metrics.

NVO and ZVSA operate at a comparable scale, with $327.8B and $0 in trailing revenue. NVO is the more profitable business, keeping 37.2% of every revenue dollar as net income compared to CRL's -4.6%. On growth, LLY holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricZVSA logoZVSAZyVersa Therapeut…LLY logoLLYEli Lilly and Com…CRL logoCRLCharles River Lab…NVO logoNVONovo Nordisk A/SKO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …
RevenueTrailing 12 months$0$72.2B$4.0B$327.8B$49.3B$280.3B
EBITDAEarnings before interest/tax-$24M$34.7B$824M$170.2B$15.5B$81.4B
Net IncomeAfter-tax profit-$1.8B$25.3B-$185M$122.0B$13.7B$57.0B
Free Cash FlowCash after capex-$4.1B$13.6B$391M$31.0B$12.6B$100.9B
Gross MarginGross profit ÷ Revenue+83.5%+31.9%+81.8%+61.7%+60.0%
Operating MarginEBIT ÷ Revenue+45.9%+11.8%+45.3%+29.3%+25.9%
Net MarginNet income ÷ Revenue+35.0%-4.6%+37.2%+27.8%+20.4%
FCF MarginFCF ÷ Revenue+18.8%+9.7%+9.5%+25.5%+36.0%
Rev. Growth (YoY)Latest quarter vs prior year+55.5%+1.2%+24.0%+12.1%
EPS Growth (YoY)Latest quarter vs prior year+69.9%+169.9%-160.0%+67.1%+18.2%+16.0%
LLY leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

NVO leads this category, winning 3 of 7 comparable metrics.

At 12.3x trailing earnings, NVO trades at a 75% valuation discount to LLY's 49.4x P/E. Adjusting for growth (PEG ratio), NVO offers better value at 0.60x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.

MetricZVSA logoZVSAZyVersa Therapeut…LLY logoLLYEli Lilly and Com…CRL logoCRLCharles River Lab…NVO logoNVONovo Nordisk A/SKO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …
Market CapShares × price$1.6B$1.07T$9.0B$195.0B$355.6B$896.0B
Enterprise ValueMkt cap + debt − cash$1.5B$1.11T$11.9B$211.2B$390.8B$1.50T
Trailing P/EPrice ÷ TTM EPS-0.05x49.37x-64.44x12.31x27.18x16.00x
Forward P/EPrice ÷ next-FY EPS est.30.95x16.90x2.03x25.27x14.40x
PEG RatioP/E ÷ EPS growth rate1.71x0.60x2.43x0.90x
EV / EBITDAEnterprise value multiple35.38x13.04x9.12x26.39x18.36x
Price / SalesMarket cap ÷ Revenue16.42x2.25x4.08x7.42x3.20x
Price / BookPrice ÷ Book value/share38.34x2.89x6.50x10.40x2.47x
Price / FCFMarket cap ÷ FCF119.31x17.42x43.48x67.15x8.88x
NVO leads this category, winning 3 of 7 comparable metrics.

Profitability & Efficiency

LLY leads this category, winning 5 of 9 comparable metrics.

LLY delivers a 101.2% return on equity — every $100 of shareholder capital generates $101 in annual profit, vs $-6 for CRL. NVO carries lower financial leverage with a 0.67x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), LLY scores 8/9 vs ZVSA's 2/9, reflecting strong financial health.

MetricZVSA logoZVSAZyVersa Therapeut…LLY logoLLYEli Lilly and Com…CRL logoCRLCharles River Lab…NVO logoNVONovo Nordisk A/SKO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …
ROE (TTM)Return on equity+101.2%-5.7%+66.4%+41.1%+15.9%
ROA (TTM)Return on assets-6.5%+22.7%-2.5%+23.3%+13.1%+1.3%
ROICReturn on invested capital+41.8%+6.3%+36.2%+15.8%+4.5%
ROCEReturn on capital employed+46.6%+8.1%+44.4%+17.3%+8.9%
Piotroski ScoreFundamental quality 0–9284575
Debt / EquityFinancial leverage1.60x0.95x0.67x1.33x2.60x
Net DebtTotal debt minus cash-$102M$35.3B$2.9B$104.5B$35.2B$599.0B
Cash & Equiv.Liquid assets$102M$7.2B$214M$26.5B$10.3B$343.3B
Total DebtShort + long-term debt$0$42.5B$3.1B$131.0B$45.5B$942.4B
Interest CoverageEBIT ÷ Interest expense-46.26x35.68x4.29x18.90x10.70x0.74x
LLY leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

LLY leads this category, winning 5 of 6 comparable metrics.

A $10,000 investment in LLY five years ago would be worth $51,207 today (with dividends reinvested), compared to $1 for ZVSA. Over the past 12 months, LLY leads with a +40.3% total return vs ZVSA's -73.2%. The 3-year compound annual growth rate (CAGR) favors LLY at 37.2% vs ZVSA's -88.7% — a key indicator of consistent wealth creation.

MetricZVSA logoZVSAZyVersa Therapeut…LLY logoLLYEli Lilly and Com…CRL logoCRLCharles River Lab…NVO logoNVONovo Nordisk A/SKO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …
YTD ReturnYear-to-date+44.4%+5.2%-7.4%-13.9%+20.3%-0.5%
1-Year ReturnPast 12 months-73.2%+40.3%+23.5%-43.6%+17.2%+21.8%
3-Year ReturnCumulative with dividends-99.9%+158.2%-8.7%-38.6%+47.0%+138.2%
5-Year ReturnCumulative with dividends-100.0%+412.1%-47.2%+19.3%+65.6%+118.2%
10-Year ReturnCumulative with dividends-100.0%+1484.6%+122.4%+95.7%+121.1%+465.8%
CAGR (3Y)Annualised 3-year return-88.7%+37.2%-3.0%-15.0%+13.7%+33.6%
LLY leads this category, winning 5 of 6 comparable metrics.

Risk & Volatility

KO leads this category, winning 2 of 2 comparable metrics.

KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than NVO's 1.47 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs ZVSA's 11.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricZVSA logoZVSAZyVersa Therapeut…LLY logoLLYEli Lilly and Com…CRL logoCRLCharles River Lab…NVO logoNVONovo Nordisk A/SKO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …
Beta (5Y)Sensitivity to S&P 5000.29x0.53x1.39x1.47x-0.20x0.94x
52-Week HighHighest price in past year$1.67$1182.73$228.88$81.44$84.04$337.25
52-Week LowLowest price in past year$0.11$623.78$143.06$35.12$65.35$262.71
% of 52W HighCurrent price vs 52-week peak+11.7%+95.8%+81.9%+53.9%+98.3%+95.1%
RSI (14)Momentum oscillator 0–10044.170.060.852.460.659.1
Avg Volume (50D)Average daily shares traded5K2.6M767K14.8M12.7M7.0M
KO leads this category, winning 2 of 2 comparable metrics.

Analyst Outlook

Evenly matched — NVO and KO each lead in 1 of 2 comparable metrics.

Analyst consensus: ZVSA as "Buy", LLY as "Buy", CRL as "Buy", NVO as "Buy", KO as "Buy", JPM as "Buy". Consensus price targets imply 13.7% upside for CRL (target: $213) vs 2.6% for NVO (target: $45). For income investors, NVO offers the higher dividend yield at 4.10% vs LLY's 0.53%.

MetricZVSA logoZVSAZyVersa Therapeut…LLY logoLLYEli Lilly and Com…CRL logoCRLCharles River Lab…NVO logoNVONovo Nordisk A/SKO logoKOThe Coca-Cola Com…JPM logoJPMJPMorgan Chase & …
Analyst RatingConsensus buy/hold/sellBuyBuyBuyBuyBuyBuy
Price TargetConsensus 12-month target$1268.94$213.17$45.00$86.13$339.75
# AnalystsCovering analysts14537394861
Dividend YieldAnnual dividend ÷ price+0.5%+4.1%+2.5%+1.9%
Dividend StreakConsecutive years of raises11115615
Dividend / ShareAnnual DPS$6.00$11.64$2.04$5.95
Buyback YieldShare repurchases ÷ mkt cap0.0%+0.4%+4.0%+0.1%+0.2%+3.9%
Evenly matched — NVO and KO each lead in 1 of 2 comparable metrics.
Key Takeaway

LLY leads in 3 of 6 categories (Income & Cash Flow, Profitability & Efficiency). NVO leads in 1 (Valuation Metrics). 1 tied.

Best OverallEli Lilly and Company (LLY)Leads 3 of 6 categories
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ZVSA vs LLY vs CRL vs NVO vs KO vs JPM: Key Questions Answered

10 questions · data-driven answers · updated daily

01

Is ZVSA or LLY or CRL or NVO or KO or JPM a better buy right now?

For growth investors, Eli Lilly and Company (LLY) is the stronger pick with 44.

7% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). Novo Nordisk A/S (NVO) offers the better valuation at 12. 3x trailing P/E (2. 0x forward), making it the more compelling value choice. Analysts rate ZyVersa Therapeutics, Inc. (ZVSA) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which has the better valuation — ZVSA or LLY or CRL or NVO or KO or JPM?

On trailing P/E, Novo Nordisk A/S (NVO) is the cheapest at 12.

3x versus Eli Lilly and Company at 49. 4x. On forward P/E, Novo Nordisk A/S is actually cheaper at 2. 0x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Novo Nordisk A/S wins at 0. 10x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.

03

Which is the better long-term investment — ZVSA or LLY or CRL or NVO or KO or JPM?

Over the past 5 years, Eli Lilly and Company (LLY) delivered a total return of +412.

1%, compared to -100. 0% for ZyVersa Therapeutics, Inc. (ZVSA). Over 10 years, the gap is even starker: LLY returned +1485% versus ZVSA's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

04

Which is safer — ZVSA or LLY or CRL or NVO or KO or JPM?

By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.

20β versus Novo Nordisk A/S's 1. 47β — meaning NVO is approximately -834% more volatile than KO relative to the S&P 500. On balance sheet safety, Novo Nordisk A/S (NVO) carries a lower debt/equity ratio of 67% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.

05

Which is growing faster — ZVSA or LLY or CRL or NVO or KO or JPM?

By revenue growth (latest reported year), Eli Lilly and Company (LLY) is pulling ahead at 44.

7% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: Eli Lilly and Company grew EPS 96. 0% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, LLY leads at 31. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

06

Which has better profit margins — ZVSA or LLY or CRL or NVO or KO or JPM?

Novo Nordisk A/S (NVO) is the more profitable company, earning 33.

1% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 33. 1% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: LLY leads at 45. 6% versus 0. 0% for ZVSA. At the gross margin level — before operating expenses — LLY leads at 83. 8%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

07

Is ZVSA or LLY or CRL or NVO or KO or JPM more undervalued right now?

The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.

By this metric, Novo Nordisk A/S (NVO) is the more undervalued stock at a PEG of 0. 10x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Novo Nordisk A/S (NVO) trades at 2. 0x forward P/E versus 30. 9x for Eli Lilly and Company — 28. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for CRL: 13. 7% to $213. 17.

08

Which pays a better dividend — ZVSA or LLY or CRL or NVO or KO or JPM?

In this comparison, NVO (4.

1% yield), KO (2. 5% yield), JPM (1. 9% yield), LLY (0. 5% yield) pay a dividend. ZVSA, CRL do not pay a meaningful dividend and should not be held primarily for income.

09

Is ZVSA or LLY or CRL or NVO or KO or JPM better for a retirement portfolio?

For long-horizon retirement investors, Eli Lilly and Company (LLY) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0.

53), 0. 5% yield, +1485% 10Y return). Both have compounded well over 10 years (LLY: +1485%, CRL: +122. 4%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

10

What are the main differences between ZVSA and LLY and CRL and NVO and KO and JPM?

These companies operate in different sectors (ZVSA (Healthcare) and LLY (Healthcare) and CRL (Healthcare) and NVO (Healthcare) and KO (Consumer Defensive) and JPM (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: ZVSA is a small-cap quality compounder stock; LLY is a mega-cap high-growth stock; CRL is a small-cap quality compounder stock; NVO is a mid-cap deep-value stock; KO is a large-cap quality compounder stock; JPM is a large-cap deep-value stock. LLY, NVO, KO, JPM pay a dividend while ZVSA, CRL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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