Biotechnology
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Side-by-side financial analysisStock Comparison
ZVSA vs VKTX vs JPM vs KO vs CRL
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Banks - Diversified
Beverages - Non-Alcoholic
Medical - Diagnostics & Research
ZVSA vs VKTX vs JPM vs KO vs CRL — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||
|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Banks - Diversified | Beverages - Non-Alcoholic | Medical - Diagnostics & Research |
| Market Cap | $1.58B | $3.33B | $896.00B | $355.61B | $9.03B |
| Revenue (TTM) | $0.00 | $0.00 | $280.33B | $49.28B | $4.03B |
| Net Income (TTM) | $-1.82B | $-472M | $57.05B | $13.70B | $-185M |
| Gross Margin | — | — | 60.0% | 61.7% | 31.9% |
| Operating Margin | — | — | 25.9% | 29.3% | 11.8% |
| Forward P/E | — | — | 14.4x | 25.3x | 16.9x |
| Total Debt | $0.00 | $137K | $942.38B | $45.49B | $3.07B |
| Cash & Equiv. | $102M | $166M | $343.34B | $10.27B | $214M |
ZVSA vs VKTX vs JPM vs KO vs CRL — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Feb 22 | Jun 26 | Return |
|---|---|---|---|
| ZyVersa Therapeutic… (ZVSA) | 100 | 0.0 | -100.0% |
| Viking Therapeutics… (VKTX) | 100 | 858.2 | +758.2% |
| JPMorgan Chase & Co. (JPM) | 100 | 226.2 | +126.2% |
| The Coca-Cola Compa… (KO) | 100 | 132.7 | +32.7% |
| Charles River Labor… (CRL) | 100 | 64.4 | -35.6% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ZVSA vs VKTX vs JPM vs KO vs CRL
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ZVSA ranks third and is worth considering specifically for stability.
- Beta 0.29 vs VKTX's 1.64
VKTX is the clearest fit if your priority is long-term compounding and sleep-well-at-night.
- 22.0% 10Y total return vs JPM's 465.8%
- Lower volatility, beta 1.64, Low D/E 0.0%, current ratio 9.33x
JPM is the #2 pick in this set and the best alternative if valuation efficiency and defensive is your priority.
- PEG 0.81 vs KO's 2.26
- Beta 0.94, yield 1.9%, current ratio 0.52x
- 3.3% NII/revenue growth vs VKTX's -270.1%
- Lower P/E (14.4x vs 16.9x)
KO carries the broadest edge in this set and is the clearest fit for income & stability and growth exposure.
- Dividend streak 56 yrs, beta -0.20, yield 2.5%
- Rev growth 1.9%, EPS growth 23.6%, 3Y rev CAGR 3.7%
- 27.8% margin vs CRL's -4.6%
- 2.5% yield, 56-year raise streak, vs JPM's 1.9%, (3 stocks pay no dividend)
CRL is the clearest fit if your priority is momentum.
- +23.5% vs ZVSA's -73.2%
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 3.3% NII/revenue growth vs VKTX's -270.1% | |
| Value | Lower P/E (14.4x vs 16.9x) | |
| Quality / Margins | 27.8% margin vs CRL's -4.6% | |
| Stability / Safety | Beta 0.29 vs VKTX's 1.64 | |
| Dividends | 2.5% yield, 56-year raise streak, vs JPM's 1.9%, (3 stocks pay no dividend) | |
| Momentum (1Y) | +23.5% vs ZVSA's -73.2% | |
| Efficiency (ROA) | 13.1% ROA vs ZVSA's -6.5% |
ZVSA vs VKTX vs JPM vs KO vs CRL — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
ZVSA vs VKTX vs JPM vs KO vs CRL — Financial Metrics
Side-by-side numbers across 5 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
KO leads in 4 of 6 categories
JPM leads 1 • ZVSA leads 0 • VKTX leads 0 • CRL leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
KO leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JPM and VKTX operate at a comparable scale, with $280.3B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to CRL's -4.6%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||
|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $280.3B | $49.3B | $4.0B |
| EBITDAEarnings before interest/tax | -$24M | -$502M | $81.4B | $15.5B | $824M |
| Net IncomeAfter-tax profit | -$1.8B | -$472M | $57.0B | $13.7B | -$185M |
| Free Cash FlowCash after capex | -$4.1B | -$340M | $100.9B | $12.6B | $391M |
| Gross MarginGross profit ÷ Revenue | — | — | +60.0% | +61.7% | +31.9% |
| Operating MarginEBIT ÷ Revenue | — | — | +25.9% | +29.3% | +11.8% |
| Net MarginNet income ÷ Revenue | — | — | +20.4% | +27.8% | -4.6% |
| FCF MarginFCF ÷ Revenue | — | — | +36.0% | +25.5% | +9.7% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | — | +12.1% | +1.2% |
| EPS Growth (YoY)Latest quarter vs prior year | +69.9% | -2.3% | +16.0% | +18.2% | -160.0% |
Valuation Metrics
JPM leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 16.0x trailing earnings, JPM trades at a 41% valuation discount to KO's 27.2x P/E. Adjusting for growth (PEG ratio), JPM offers better value at 0.90x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||
|---|---|---|---|---|---|
| Market CapShares × price | $1.6B | $3.3B | $896.0B | $355.6B | $9.0B |
| Enterprise ValueMkt cap + debt − cash | $1.5B | $3.2B | $1.50T | $390.8B | $11.9B |
| Trailing P/EPrice ÷ TTM EPS | -0.05x | -9.01x | 16.00x | 27.18x | -64.44x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 14.40x | 25.27x | 16.90x |
| PEG RatioP/E ÷ EPS growth rate | — | — | 0.90x | 2.43x | — |
| EV / EBITDAEnterprise value multiple | — | — | 18.36x | 26.39x | 13.04x |
| Price / SalesMarket cap ÷ Revenue | — | — | 3.20x | 7.42x | 2.25x |
| Price / BookPrice ÷ Book value/share | — | 5.07x | 2.47x | 10.40x | 2.89x |
| Price / FCFMarket cap ÷ FCF | — | — | 8.88x | 67.15x | 17.42x |
Profitability & Efficiency
KO leads this category, winning 6 of 9 comparable metrics.
Profitability & Efficiency
KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-71 for VKTX. VKTX carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs VKTX's 2/9, reflecting strong financial health.
| Metric | |||||
|---|---|---|---|---|---|
| ROE (TTM)Return on equity | — | -71.3% | +15.9% | +41.1% | -5.7% |
| ROA (TTM)Return on assets | -6.5% | -65.3% | +1.3% | +13.1% | -2.5% |
| ROICReturn on invested capital | — | -44.4% | +4.5% | +15.8% | +6.3% |
| ROCEReturn on capital employed | — | -51.8% | +8.9% | +17.3% | +8.1% |
| Piotroski ScoreFundamental quality 0–9 | 2 | 2 | 5 | 7 | 4 |
| Debt / EquityFinancial leverage | — | 0.00x | 2.60x | 1.33x | 0.95x |
| Net DebtTotal debt minus cash | -$102M | -$166M | $599.0B | $35.2B | $2.9B |
| Cash & Equiv.Liquid assets | $102M | $166M | $343.3B | $10.3B | $214M |
| Total DebtShort + long-term debt | $0 | $137,000 | $942.4B | $45.5B | $3.1B |
| Interest CoverageEBIT ÷ Interest expense | -46.26x | -15687.44x | 0.74x | 10.70x | 4.29x |
Total Returns (Dividends Reinvested)
Evenly matched — VKTX and JPM each lead in 2 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in VKTX five years ago would be worth $47,286 today (with dividends reinvested), compared to $1 for ZVSA. Over the past 12 months, CRL leads with a +23.5% total return vs ZVSA's -73.2%. The 3-year compound annual growth rate (CAGR) favors JPM at 33.6% vs ZVSA's -88.7% — a key indicator of consistent wealth creation.
| Metric | |||||
|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +44.4% | -18.8% | -0.5% | +20.3% | -7.4% |
| 1-Year ReturnPast 12 months | -73.2% | +0.6% | +21.8% | +17.2% | +23.5% |
| 3-Year ReturnCumulative with dividends | -99.9% | +21.1% | +138.2% | +47.0% | -8.7% |
| 5-Year ReturnCumulative with dividends | -100.0% | +372.9% | +118.2% | +65.6% | -47.2% |
| 10-Year ReturnCumulative with dividends | -100.0% | +2200.0% | +465.8% | +121.1% | +122.4% |
| CAGR (3Y)Annualised 3-year return | -88.7% | +6.6% | +33.6% | +13.7% | -3.0% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than VKTX's 1.64 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs ZVSA's 11.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||
|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.29x | 1.64x | 0.94x | -0.20x | 1.39x |
| 52-Week HighHighest price in past year | $1.67 | $43.15 | $337.25 | $84.04 | $228.88 |
| 52-Week LowLowest price in past year | $0.11 | $22.96 | $262.71 | $65.35 | $143.06 |
| % of 52W HighCurrent price vs 52-week peak | +11.7% | +66.6% | +95.1% | +98.3% | +81.9% |
| RSI (14)Momentum oscillator 0–100 | 44.1 | 41.5 | 59.1 | 60.6 | 60.8 |
| Avg Volume (50D)Average daily shares traded | 5K | 2.0M | 7.0M | 12.7M | 767K |
Analyst Outlook
KO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ZVSA as "Buy", VKTX as "Buy", JPM as "Buy", KO as "Buy", CRL as "Buy". Consensus price targets imply 225.6% upside for VKTX (target: $94) vs 4.2% for KO (target: $86). For income investors, KO offers the higher dividend yield at 2.46% vs JPM's 1.86%.
| Metric | |||||
|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | — | $93.60 | $339.75 | $86.13 | $213.17 |
| # AnalystsCovering analysts | 1 | 24 | 61 | 48 | 37 |
| Dividend YieldAnnual dividend ÷ price | — | — | +1.9% | +2.5% | — |
| Dividend StreakConsecutive years of raises | — | — | 15 | 56 | 1 |
| Dividend / ShareAnnual DPS | — | — | $5.95 | $2.04 | — |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | +3.9% | +0.2% | +4.0% |
KO leads in 4 of 6 categories (Income & Cash Flow, Profitability & Efficiency). JPM leads in 1 (Valuation Metrics). 1 tied.
ZVSA vs VKTX vs JPM vs KO vs CRL: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ZVSA or VKTX or JPM or KO or CRL a better buy right now?
For growth investors, JPMorgan Chase & Co.
(JPM) is the stronger pick with 3. 3% revenue growth year-over-year, versus -0. 9% for Charles River Laboratories International, Inc. (CRL). JPMorgan Chase & Co. (JPM) offers the better valuation at 16. 0x trailing P/E (14. 4x forward), making it the more compelling value choice. Analysts rate ZyVersa Therapeutics, Inc. (ZVSA) a "Buy" — based on 1 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ZVSA or VKTX or JPM or KO or CRL?
On trailing P/E, JPMorgan Chase & Co.
(JPM) is the cheapest at 16. 0x versus The Coca-Cola Company at 27. 2x. On forward P/E, JPMorgan Chase & Co. is actually cheaper at 14. 4x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: JPMorgan Chase & Co. wins at 0. 81x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — ZVSA or VKTX or JPM or KO or CRL?
Over the past 5 years, Viking Therapeutics, Inc.
(VKTX) delivered a total return of +372. 9%, compared to -100. 0% for ZyVersa Therapeutics, Inc. (ZVSA). Over 10 years, the gap is even starker: VKTX returned +22. 0% versus ZVSA's -100. 0%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ZVSA or VKTX or JPM or KO or CRL?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Viking Therapeutics, Inc. 's 1. 64β — meaning VKTX is approximately -921% more volatile than KO relative to the S&P 500. On balance sheet safety, Viking Therapeutics, Inc. (VKTX) carries a lower debt/equity ratio of 0% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — ZVSA or VKTX or JPM or KO or CRL?
By revenue growth (latest reported year), JPMorgan Chase & Co.
(JPM) is pulling ahead at 3. 3% versus -0. 9% for Charles River Laboratories International, Inc. (CRL). On earnings-per-share growth, the picture is similar: ZyVersa Therapeutics, Inc. grew EPS 50. 7% year-over-year, compared to -1555. 0% for Charles River Laboratories International, Inc.. Over a 3-year CAGR, KO leads at 3. 7% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ZVSA or VKTX or JPM or KO or CRL?
The Coca-Cola Company (KO) is the more profitable company, earning 27.
3% net margin versus -3. 6% for Charles River Laboratories International, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus 0. 0% for VKTX. At the gross margin level — before operating expenses — KO leads at 61. 6%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ZVSA or VKTX or JPM or KO or CRL more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, JPMorgan Chase & Co. (JPM) is the more undervalued stock at a PEG of 0. 81x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, JPMorgan Chase & Co. (JPM) trades at 14. 4x forward P/E versus 25. 3x for The Coca-Cola Company — 10. 9x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for VKTX: 225. 6% to $93. 60.
08Which pays a better dividend — ZVSA or VKTX or JPM or KO or CRL?
In this comparison, KO (2.
5% yield), JPM (1. 9% yield) pay a dividend. ZVSA, VKTX, CRL do not pay a meaningful dividend and should not be held primarily for income.
09Is ZVSA or VKTX or JPM or KO or CRL better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). Viking Therapeutics, Inc. (VKTX) carries a higher beta of 1. 64 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, VKTX: +22. 0%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ZVSA and VKTX and JPM and KO and CRL?
These companies operate in different sectors (ZVSA (Healthcare) and VKTX (Healthcare) and JPM (Financial Services) and KO (Consumer Defensive) and CRL (Healthcare)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: ZVSA is a small-cap quality compounder stock; VKTX is a small-cap quality compounder stock; JPM is a large-cap deep-value stock; KO is a large-cap quality compounder stock; CRL is a small-cap quality compounder stock. JPM, KO pay a dividend while ZVSA, VKTX, CRL do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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