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Stock Comparison

GLUE vs KYMR vs JPM

Revenue, margins, valuation, and 5-year total return — side by side.

Live fundamentals10-year financials5-year price chart
GLUE
Monte Rosa Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$1.11B
5Y Perf.-19.7%
KYMR
Kymera Therapeutics, Inc.

Biotechnology

HealthcareNASDAQ • US
Market Cap$6.77B
5Y Perf.+77.7%
JPM
JPMorgan Chase & Co.

Banks - Diversified

Financial ServicesNYSE • US
Market Cap$875.80B
5Y Perf.+106.2%

GLUE vs KYMR vs JPM — Key Financials

Market cap, revenue, margins, and valuation side-by-side.

Company Snapshot
GLUE logoGLUE
KYMR logoKYMR
JPM logoJPM
IndustryBiotechnologyBiotechnologyBanks - Diversified
Market Cap$1.11B$6.77B$875.80B
Revenue (TTM)$43M$51M$280.33B
Net Income (TTM)$-130M$-315M$57.05B
Gross Margin95.3%33.2%60.0%
Operating Margin-345.2%-7.0%25.9%
Forward P/E14.1x
Total Debt$39M$82M$942.38B
Cash & Equiv.$130M$357M$343.34B

GLUE vs KYMR vs JPMLong-Term Stock Performance

Price return indexed to 100 at period start. Dividends excluded.

GLUE
KYMR
JPM
StockJun 21Jun 26Return
Monte Rosa Therapeu… (GLUE)10080.3-19.7%
Kymera Therapeutics… (KYMR)100177.7+77.7%
JPMorgan Chase & Co. (JPM)100206.2+106.2%

Price return only. Dividends and distributions are not included.

Quick Verdict: GLUE vs KYMR vs JPM

Each card shows where this stock fits in a portfolio — not just who wins on paper.

Bottom line: JPM leads in 3 of 6 categories, making it the strongest pick for profitability and margin quality and dividend income and shareholder returns. Monte Rosa Therapeutics, Inc. is the stronger pick specifically for growth and revenue expansion and recent price momentum and sentiment. This set spans 2 sectors — these stocks serve different portfolio roles, not just different price points.
🥇JPM emerged as the overall leader. Track its performance:
GLUE
Monte Rosa Therapeutics, Inc.
The Growth Play

GLUE is the clearest fit if your priority is growth exposure.

  • Rev growth 63.5%, EPS growth 53.1%
  • 63.5% revenue growth vs KYMR's -16.7%
  • +238.6% vs JPM's +19.1%
Best for: growth exposure
KYMR
Kymera Therapeutics, Inc.
The Income Pick

KYMR is the clearest fit if your priority is income & stability and sleep-well-at-night.

  • beta 0.90
  • Lower volatility, beta 0.90, Low D/E 5.2%, current ratio 10.47x
  • Beta 0.90, current ratio 10.47x
Best for: income & stability and sleep-well-at-night
JPM
JPMorgan Chase & Co.
The Banking Pick

JPM carries the broadest edge in this set and is the clearest fit for long-term compounding.

  • 454.4% 10Y total return vs KYMR's 149.4%
  • 20.4% margin vs KYMR's -6.1%
  • 1.9% yield; 15-year raise streak; the other 2 pay no meaningful dividend
Best for: long-term compounding
See the full category breakdown
CategoryWinnerWhy
GrowthGLUE logoGLUE63.5% revenue growth vs KYMR's -16.7%
Quality / MarginsJPM logoJPM20.4% margin vs KYMR's -6.1%
Stability / SafetyKYMR logoKYMRBeta 0.90 vs GLUE's 1.30, lower leverage
DividendsJPM logoJPM1.9% yield; 15-year raise streak; the other 2 pay no meaningful dividend
Momentum (1Y)GLUE logoGLUE+238.6% vs JPM's +19.1%
Efficiency (ROA)JPM logoJPM1.3% ROA vs GLUE's -25.9%, ROIC 4.5% vs -44.2%

GLUE vs KYMR vs JPM — Revenue Breakdown by Segment

How each company's revenue is distributed across its business units

GLUEMonte Rosa Therapeutics, Inc.

Segment breakdown not available.

KYMRKymera Therapeutics, Inc.

Segment breakdown not available.

JPMJPMorgan Chase & Co.
FY 2025
Commercial And Investment Bank
43.0%$78.5B
Consumer & Community Banking
41.7%$76.0B
Asset and Wealth Management Segment
13.2%$24.1B
Segment Reporting, Reconciling Item, Corporate Nonsegment
3.9%$7.0B
Segment Reconciling Items
-1.7%$-3,134,000,000

GLUE vs KYMR vs JPM — Financial Metrics

Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.

BEST OVERALLJPMLAGGINGGLUE

Income & Cash Flow (Last 12 Months)

JPM leads this category, winning 4 of 6 comparable metrics.

JPM is the larger business by revenue, generating $280.3B annually — 6526.5x GLUE's $43M. JPM is the more profitable business, keeping 20.4% of every revenue dollar as net income compared to KYMR's -6.1%. On growth, KYMR holds the edge at +55.5% YoY revenue growth, suggesting stronger near-term business momentum.

MetricGLUE logoGLUEMonte Rosa Therap…KYMR logoKYMRKymera Therapeuti…JPM logoJPMJPMorgan Chase & …
RevenueTrailing 12 months$43M$51M$280.3B
EBITDAEarnings before interest/tax-$140M-$352M$81.4B
Net IncomeAfter-tax profit-$130M-$315M$57.0B
Free Cash FlowCash after capex-$20M-$244M$100.9B
Gross MarginGross profit ÷ Revenue+95.3%+33.2%+60.0%
Operating MarginEBIT ÷ Revenue-3.5%-7.0%+25.9%
Net MarginNet income ÷ Revenue-3.0%-6.1%+20.4%
FCF MarginFCF ÷ Revenue-45.8%-4.7%+36.0%
Rev. Growth (YoY)Latest quarter vs prior year-95.0%+55.5%
EPS Growth (YoY)Latest quarter vs prior year-2.2%+13.4%+16.0%
JPM leads this category, winning 4 of 6 comparable metrics.

Valuation Metrics

JPM leads this category, winning 2 of 3 comparable metrics.
MetricGLUE logoGLUEMonte Rosa Therap…KYMR logoKYMRKymera Therapeuti…JPM logoJPMJPMorgan Chase & …
Market CapShares × price$1.1B$6.8B$875.8B
Enterprise ValueMkt cap + debt − cash$1.0B$6.5B$1.47T
Trailing P/EPrice ÷ TTM EPS-37.17x-22.48x15.64x
Forward P/EPrice ÷ next-FY EPS est.14.08x
PEG RatioP/E ÷ EPS growth rate1.20x
EV / EBITDAEnterprise value multiple18.11x
Price / SalesMarket cap ÷ Revenue9.00x172.78x3.13x
Price / BookPrice ÷ Book value/share6.10x4.43x2.42x
Price / FCFMarket cap ÷ FCF8.68x
JPM leads this category, winning 2 of 3 comparable metrics.

Profitability & Efficiency

JPM leads this category, winning 5 of 9 comparable metrics.

JPM delivers a 15.9% return on equity — every $100 of shareholder capital generates $16 in annual profit, vs $-41 for GLUE. KYMR carries lower financial leverage with a 0.05x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), GLUE scores 6/9 vs KYMR's 4/9, reflecting solid financial health.

MetricGLUE logoGLUEMonte Rosa Therap…KYMR logoKYMRKymera Therapeuti…JPM logoJPMJPMorgan Chase & …
ROE (TTM)Return on equity-41.0%-25.0%+15.9%
ROA (TTM)Return on assets-25.9%-22.3%+1.3%
ROICReturn on invested capital-44.2%-24.9%+4.5%
ROCEReturn on capital employed-16.3%-27.2%+8.9%
Piotroski ScoreFundamental quality 0–9645
Debt / EquityFinancial leverage0.17x0.05x2.60x
Net DebtTotal debt minus cash-$91M-$275M$599.0B
Cash & Equiv.Liquid assets$130M$357M$343.3B
Total DebtShort + long-term debt$39M$82M$942.4B
Interest CoverageEBIT ÷ Interest expense-2119.53x0.74x
JPM leads this category, winning 5 of 9 comparable metrics.

Total Returns (Dividends Reinvested)

KYMR leads this category, winning 3 of 6 comparable metrics.

A $10,000 investment in JPM five years ago would be worth $20,999 today (with dividends reinvested), compared to $8,074 for GLUE. Over the past 12 months, GLUE leads with a +238.6% total return vs JPM's +19.1%. The 3-year compound annual growth rate (CAGR) favors KYMR at 48.9% vs JPM's 32.6% — a key indicator of consistent wealth creation.

MetricGLUE logoGLUEMonte Rosa Therap…KYMR logoKYMRKymera Therapeuti…JPM logoJPMJPMorgan Chase & …
YTD ReturnYear-to-date+11.7%+14.0%-2.8%
1-Year ReturnPast 12 months+238.6%+71.4%+19.1%
3-Year ReturnCumulative with dividends+149.6%+230.0%+133.1%
5-Year ReturnCumulative with dividends-19.3%+64.1%+110.0%
10-Year ReturnCumulative with dividends-19.3%+149.4%+454.4%
CAGR (3Y)Annualised 3-year return+35.7%+48.9%+32.6%
KYMR leads this category, winning 3 of 6 comparable metrics.

Risk & Volatility

Evenly matched — KYMR and JPM each lead in 1 of 2 comparable metrics.

KYMR is the less volatile stock with a 0.90 beta — it tends to amplify market swings less than GLUE's 1.30 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. JPM currently trades 93.0% from its 52-week high vs GLUE's 66.4% drawdown — a narrower gap to the peak suggests stronger recent price momentum.

MetricGLUE logoGLUEMonte Rosa Therap…KYMR logoKYMRKymera Therapeuti…JPM logoJPMJPMorgan Chase & …
Beta (5Y)Sensitivity to S&P 5001.29x0.91x0.94x
52-Week HighHighest price in past year$25.77$103.00$337.25
52-Week LowLowest price in past year$4.12$36.65$262.71
% of 52W HighCurrent price vs 52-week peak+66.4%+80.5%+93.0%
RSI (14)Momentum oscillator 0–10036.447.754.8
Avg Volume (50D)Average daily shares traded818K493K7.0M
Evenly matched — KYMR and JPM each lead in 1 of 2 comparable metrics.

Analyst Outlook

Insufficient data to determine a leader in this category.

Analyst consensus: GLUE as "Buy", KYMR as "Buy", JPM as "Buy". Consensus price targets imply 85.7% upside for GLUE (target: $32) vs 8.1% for JPM (target: $339). JPM is the only dividend payer here at 1.90% yield — a key consideration for income-focused portfolios.

MetricGLUE logoGLUEMonte Rosa Therap…KYMR logoKYMRKymera Therapeuti…JPM logoJPMJPMorgan Chase & …
Analyst RatingConsensus buy/hold/sellBuyBuyBuy
Price TargetConsensus 12-month target$31.75$112.60$338.78
# AnalystsCovering analysts92661
Dividend YieldAnnual dividend ÷ price+1.9%
Dividend StreakConsecutive years of raises15
Dividend / ShareAnnual DPS$5.95
Buyback YieldShare repurchases ÷ mkt cap0.0%0.0%+3.9%
Insufficient data to determine a leader in this category.
Key Takeaway

JPM leads in 3 of 6 categories (Income & Cash Flow, Valuation Metrics). KYMR leads in 1 (Total Returns). 1 tied.

Best OverallJPMorgan Chase & Co. (JPM)Leads 3 of 6 categories
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GLUE vs KYMR vs JPM: Key Questions Answered

9 questions · data-driven answers · updated daily

01

Is GLUE or KYMR or JPM a better buy right now?

For growth investors, Monte Rosa Therapeutics, Inc.

(GLUE) is the stronger pick with 63. 5% revenue growth year-over-year, versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). JPMorgan Chase & Co. (JPM) offers the better valuation at 15. 6x trailing P/E (14. 1x forward), making it the more compelling value choice. Analysts rate Monte Rosa Therapeutics, Inc. (GLUE) a "Buy" — based on 9 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.

02

Which is the better long-term investment — GLUE or KYMR or JPM?

Over the past 5 years, JPMorgan Chase & Co.

(JPM) delivered a total return of +110. 0%, compared to -19. 3% for Monte Rosa Therapeutics, Inc. (GLUE). Over 10 years, the gap is even starker: JPM returned +465. 8% versus GLUE's -13. 9%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.

03

Which is safer — GLUE or KYMR or JPM?

By beta (market sensitivity over 5 years), Kymera Therapeutics, Inc.

(KYMR) is the lower-risk stock at 0. 91β versus Monte Rosa Therapeutics, Inc. 's 1. 29β — meaning GLUE is approximately 41% more volatile than KYMR relative to the S&P 500. On balance sheet safety, Kymera Therapeutics, Inc. (KYMR) carries a lower debt/equity ratio of 5% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.

04

Which is growing faster — GLUE or KYMR or JPM?

By revenue growth (latest reported year), Monte Rosa Therapeutics, Inc.

(GLUE) is pulling ahead at 63. 5% versus -16. 7% for Kymera Therapeutics, Inc. (KYMR). On earnings-per-share growth, the picture is similar: Monte Rosa Therapeutics, Inc. grew EPS 53. 1% year-over-year, compared to -23. 8% for Kymera Therapeutics, Inc.. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.

05

Which has better profit margins — GLUE or KYMR or JPM?

JPMorgan Chase & Co.

(JPM) is the more profitable company, earning 20. 4% net margin versus -794. 4% for Kymera Therapeutics, Inc. — meaning it keeps 20. 4% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: JPM leads at 26. 0% versus -891. 3% for KYMR. At the gross margin level — before operating expenses — KYMR leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.

06

Is GLUE or KYMR or JPM more undervalued right now?

Analyst consensus price targets imply the most upside for GLUE: 85.

7% to $31. 75.

07

Which pays a better dividend — GLUE or KYMR or JPM?

In this comparison, JPM (1.

9% yield) pays a dividend. GLUE, KYMR do not pay a meaningful dividend and should not be held primarily for income.

08

Is GLUE or KYMR or JPM better for a retirement portfolio?

For long-horizon retirement investors, JPMorgan Chase & Co.

(JPM) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β 0. 94), 1. 9% yield, +465. 8% 10Y return). Both have compounded well over 10 years (JPM: +465. 8%, GLUE: -13. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.

09

What are the main differences between GLUE and KYMR and JPM?

These companies operate in different sectors (GLUE (Healthcare) and KYMR (Healthcare) and JPM (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.

In terms of investment character: GLUE is a small-cap high-growth stock; KYMR is a small-cap quality compounder stock; JPM is a large-cap deep-value stock. JPM pays a dividend while GLUE, KYMR do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.

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