Biotechnology
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Side-by-side financial analysisStock Comparison
KZR vs IMVT vs ARQT vs INVA vs ABBV vs JPM vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Biotechnology
Biotechnology
Biotechnology
Drug Manufacturers - General
Banks - Diversified
Beverages - Non-Alcoholic
KZR vs IMVT vs ARQT vs INVA vs ABBV vs JPM vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||||||
|---|---|---|---|---|---|---|---|
| Industry | Biotechnology | Biotechnology | Biotechnology | Biotechnology | Drug Manufacturers - General | Banks - Diversified | Beverages - Non-Alcoholic |
| Market Cap | $54M | $6.90B | $3.05B | $1.68B | $402.80B | $896.00B | $355.61B |
| Revenue (TTM) | $0.00 | $0.00 | $416M | $424M | $61.16B | $280.33B | $49.28B |
| Net Income (TTM) | $-45M | $-506M | $-2M | $504M | $4.23B | $57.05B | $13.70B |
| Gross Margin | — | — | 90.9% | 76.2% | 70.2% | 60.0% | 61.7% |
| Operating Margin | — | — | 0.8% | 14.8% | 26.7% | 25.9% | 29.3% |
| Forward P/E | — | — | 122.5x | 6.4x | 16.0x | 14.4x | 25.3x |
| Total Debt | $2M | $72K | $6M | $269M | $69.07B | $942.38B | $45.49B |
| Cash & Equiv. | $72M | $902M | $43M | $551M | $5.23B | $343.34B | $10.27B |
KZR vs IMVT vs ARQT vs INVA vs ABBV vs JPM vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Jun 20 | May 26 | Return |
|---|---|---|---|
| Kezar Life Sciences… (KZR) | 100 | 1.4 | -98.6% |
| Immunovant, Inc. (IMVT) | 100 | 111.5 | +11.5% |
| Arcutis Biotherapeu… (ARQT) | 100 | 76.8 | -23.2% |
| Innoviva, Inc. (INVA) | 100 | 164.4 | +64.4% |
| AbbVie Inc. (ABBV) | 100 | 215.2 | +115.2% |
| JPMorgan Chase & Co. (JPM) | 100 | 333.0 | +233.0% |
| The Coca-Cola Compa… (KO) | 100 | 176.3 | +76.3% |
Price return only. Dividends and distributions are not included.
Quick Verdict: KZR vs IMVT vs ARQT vs INVA vs ABBV vs JPM vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
Among these 7 stocks, KZR doesn't own a clear edge in any measured category.
IMVT is the #2 pick in this set and the best alternative if momentum is your priority.
- +110.9% vs INVA's +6.3%
ARQT ranks third and is worth considering specifically for growth exposure.
- Rev growth 91.3%, EPS growth 88.8%, 3Y rev CAGR 367.3%
- 91.3% revenue growth vs IMVT's -22.2%
INVA carries the broadest edge in this set and is the clearest fit for sleep-well-at-night and valuation efficiency.
- Lower volatility, beta 0.06, Low D/E 22.9%, current ratio 14.64x
- PEG 0.62 vs KO's 2.26
- Lower P/E (6.4x vs 25.3x), PEG 0.62 vs 2.26
- 118.9% margin vs ARQT's -0.6%
- Beta 0.06 vs IMVT's 1.66
ABBV is the clearest fit if your priority is income & stability and defensive.
- Dividend streak 43 yrs, beta 0.14, yield 2.9%
- Beta 0.14, yield 2.9%, current ratio 0.67x
- 2.9% yield, 43-year raise streak, vs KO's 2.5%, (4 stocks pay no dividend)
JPM is the clearest fit if your priority is long-term compounding.
- 465.8% 10Y total return vs ABBV's 362.2%
In this particular matchup, KO is outpaced on most metrics by others in the set.
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 91.3% revenue growth vs IMVT's -22.2% | |
| Value | Lower P/E (6.4x vs 25.3x), PEG 0.62 vs 2.26 | |
| Quality / Margins | 118.9% margin vs ARQT's -0.6% | |
| Stability / Safety | Beta 0.06 vs IMVT's 1.66 | |
| Dividends | 2.9% yield, 43-year raise streak, vs KO's 2.5%, (4 stocks pay no dividend) | |
| Momentum (1Y) | +110.9% vs INVA's +6.3% | |
| Efficiency (ROA) | 32.4% ROA vs IMVT's -62.2% |
KZR vs IMVT vs ARQT vs INVA vs ABBV vs JPM vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
Segment breakdown not available.
KZR vs IMVT vs ARQT vs INVA vs ABBV vs JPM vs KO — Financial Metrics
Side-by-side numbers across 7 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
INVA leads in 1 of 6 categories
IMVT leads 1 • KO leads 1 • KZR leads 0 • ARQT leads 0 • ABBV leads 0 • JPM leads 0 • 3 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
Evenly matched — ARQT and INVA each lead in 2 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JPM and IMVT operate at a comparable scale, with $280.3B and $0 in trailing revenue. INVA is the more profitable business, keeping 118.9% of every revenue dollar as net income compared to ARQT's -0.6%. On growth, ARQT holds the edge at +60.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $0 | $416M | $424M | $61.2B | $280.3B | $49.3B |
| EBITDAEarnings before interest/tax | -$41M | -$532M | $6M | $86M | $24.5B | $81.4B | $15.5B |
| Net IncomeAfter-tax profit | -$45M | -$506M | -$2M | $504M | $4.2B | $57.0B | $13.7B |
| Free Cash FlowCash after capex | -$42M | -$407M | $27M | $181M | $18.7B | $100.9B | $12.6B |
| Gross MarginGross profit ÷ Revenue | — | — | +90.9% | +76.2% | +70.2% | +60.0% | +61.7% |
| Operating MarginEBIT ÷ Revenue | — | — | +0.8% | +14.8% | +26.7% | +25.9% | +29.3% |
| Net MarginNet income ÷ Revenue | — | — | -0.6% | +118.9% | +6.9% | +20.4% | +27.8% |
| FCF MarginFCF ÷ Revenue | — | — | +6.5% | +42.6% | +30.6% | +36.0% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | — | — | +60.1% | +10.6% | +10.0% | — | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | +65.6% | -14.1% | +55.0% | +4.0% | +57.4% | +16.0% | +18.2% |
Valuation Metrics
INVA leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 6.9x trailing earnings, INVA trades at a 93% valuation discount to ABBV's 96.1x P/E. Adjusting for growth (PEG ratio), INVA offers better value at 0.67x vs KO's 2.43x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Market CapShares × price | $54M | $6.9B | $3.0B | $1.7B | $402.8B | $896.0B | $355.6B |
| Enterprise ValueMkt cap + debt − cash | -$16M | $6.0B | $3.0B | $1.4B | $466.6B | $1.50T | $390.8B |
| Trailing P/EPrice ÷ TTM EPS | -0.95x | -12.14x | -187.54x | 6.89x | 96.09x | 16.00x | 27.18x |
| Forward P/EPrice ÷ next-FY EPS est. | — | — | 122.45x | 6.36x | 15.96x | 14.40x | 25.27x |
| PEG RatioP/E ÷ EPS growth rate | — | — | — | 0.67x | — | 0.90x | 2.43x |
| EV / EBITDAEnterprise value multiple | — | — | — | 6.85x | 16.53x | 18.36x | 26.39x |
| Price / SalesMarket cap ÷ Revenue | — | — | 8.11x | 3.95x | 6.59x | 3.20x | 7.42x |
| Price / BookPrice ÷ Book value/share | 0.76x | 7.19x | 16.37x | 1.64x | — | 2.47x | 10.40x |
| Price / FCFMarket cap ÷ FCF | — | — | — | 8.57x | 22.61x | 8.88x | 67.15x |
Profitability & Efficiency
Evenly matched — IMVT and ABBV each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
ABBV delivers a 62.1% return on equity — every $100 of shareholder capital generates $62 in annual profit, vs $-68 for IMVT. IMVT carries lower financial leverage with a 0.00x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs IMVT's 2/9, reflecting strong financial health.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| ROE (TTM)Return on equity | -58.4% | -68.2% | -1.4% | +47.6% | +62.1% | +15.9% | +41.1% |
| ROA (TTM)Return on assets | -51.5% | -62.2% | -0.6% | +32.4% | +3.1% | +1.3% | +13.1% |
| ROICReturn on invested capital | -85.3% | — | -5.2% | +14.2% | +23.9% | +4.5% | +15.8% |
| ROCEReturn on capital employed | -53.8% | -68.3% | -4.3% | +12.4% | +21.5% | +8.9% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 4 | 2 | 4 | 5 | 6 | 5 | 7 |
| Debt / EquityFinancial leverage | 0.03x | 0.00x | 0.03x | 0.23x | — | 2.60x | 1.33x |
| Net DebtTotal debt minus cash | -$70M | -$902M | -$37M | -$282M | $63.8B | $599.0B | $35.2B |
| Cash & Equiv.Liquid assets | $72M | $902M | $43M | $551M | $5.2B | $343.3B | $10.3B |
| Total DebtShort + long-term debt | $2M | $72,000 | $6M | $269M | $69.1B | $942.4B | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | -38.59x | — | 2.08x | 63.45x | 3.28x | 0.74x | 10.70x |
Total Returns (Dividends Reinvested)
IMVT leads this category, winning 3 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in IMVT five years ago would be worth $31,304 today (with dividends reinvested), compared to $126 for KZR. Over the past 12 months, IMVT leads with a +110.9% total return vs INVA's +6.3%. The 3-year compound annual growth rate (CAGR) favors ARQT at 33.7% vs KZR's -69.0% — a key indicator of consistent wealth creation.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| YTD ReturnYear-to-date | +15.9% | +29.8% | -15.9% | +14.4% | +0.8% | -0.5% | +20.3% |
| 1-Year ReturnPast 12 months | +52.2% | +110.9% | +80.6% | +6.3% | +21.9% | +21.8% | +17.2% |
| 3-Year ReturnCumulative with dividends | -97.0% | +55.0% | +138.8% | +69.7% | +79.3% | +138.2% | +47.0% |
| 5-Year ReturnCumulative with dividends | -98.7% | +213.0% | -16.2% | +77.9% | +123.7% | +118.2% | +65.6% |
| 10-Year ReturnCumulative with dividends | -99.6% | +237.9% | +11.8% | +108.1% | +362.2% | +465.8% | +121.1% |
| CAGR (3Y)Annualised 3-year return | -69.0% | +15.7% | +33.7% | +19.3% | +21.5% | +33.6% | +13.7% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.20 beta — it tends to amplify market swings less than IMVT's 1.66 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.3% from its 52-week high vs ARQT's 76.7% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 0.72x | 1.66x | 1.45x | 0.06x | 0.14x | 0.94x | -0.20x |
| 52-Week HighHighest price in past year | $7.55 | $36.27 | $31.77 | $25.15 | $244.81 | $337.25 | $84.04 |
| 52-Week LowLowest price in past year | $3.53 | $14.32 | $12.72 | $16.52 | $181.73 | $262.71 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +96.6% | +92.7% | +76.7% | +90.4% | +93.0% | +95.1% | +98.3% |
| RSI (14)Momentum oscillator 0–100 | 52.4 | 57.9 | 66.4 | 50.6 | 62.8 | 59.1 | 60.6 |
| Avg Volume (50D)Average daily shares traded | 111K | 1.9M | 1.5M | 660K | 4.6M | 7.0M | 12.7M |
Analyst Outlook
Evenly matched — ABBV and KO each lead in 1 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: KZR as "Hold", IMVT as "Buy", ARQT as "Buy", INVA as "Buy", ABBV as "Buy", JPM as "Buy", KO as "Buy". Consensus price targets imply 75.9% upside for INVA (target: $40) vs -17.7% for KZR (target: $6). For income investors, ABBV offers the higher dividend yield at 2.89% vs JPM's 1.86%.
| Metric | |||||||
|---|---|---|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Hold | Buy | Buy | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $6.00 | $43.67 | $34.00 | $40.00 | $256.92 | $339.75 | $86.13 |
| # AnalystsCovering analysts | 7 | 23 | 12 | 10 | 41 | 61 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | — | — | — | +2.9% | +1.9% | +2.5% |
| Dividend StreakConsecutive years of raises | — | — | — | 2 | 43 | 15 | 56 |
| Dividend / ShareAnnual DPS | — | — | — | — | $6.57 | $5.95 | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | 0.0% | 0.0% | +0.3% | +0.2% | +3.9% | +0.2% |
INVA leads in 1 of 6 categories (Valuation Metrics). IMVT leads in 1 (Total Returns). 3 tied.
KZR vs IMVT vs ARQT vs INVA vs ABBV vs JPM vs KO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is KZR or IMVT or ARQT or INVA or ABBV or JPM or KO a better buy right now?
For growth investors, Arcutis Biotherapeutics, Inc.
(ARQT) is the stronger pick with 91. 3% revenue growth year-over-year, versus 1. 9% for The Coca-Cola Company (KO). Innoviva, Inc. (INVA) offers the better valuation at 6. 9x trailing P/E (6. 4x forward), making it the more compelling value choice. Analysts rate Immunovant, Inc. (IMVT) a "Buy" — based on 23 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — KZR or IMVT or ARQT or INVA or ABBV or JPM or KO?
On trailing P/E, Innoviva, Inc.
(INVA) is the cheapest at 6. 9x versus AbbVie Inc. at 96. 1x. On forward P/E, Innoviva, Inc. is actually cheaper at 6. 4x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: Innoviva, Inc. wins at 0. 62x versus The Coca-Cola Company's 2. 26x — a PEG below 1. 0 traditionally signals the market is underpricing earnings growth.
03Which is the better long-term investment — KZR or IMVT or ARQT or INVA or ABBV or JPM or KO?
Over the past 5 years, Immunovant, Inc.
(IMVT) delivered a total return of +213. 0%, compared to -98. 7% for Kezar Life Sciences, Inc. (KZR). Over 10 years, the gap is even starker: JPM returned +465. 8% versus KZR's -99. 6%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — KZR or IMVT or ARQT or INVA or ABBV or JPM or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Immunovant, Inc. 's 1. 66β — meaning IMVT is approximately -928% more volatile than KO relative to the S&P 500. On balance sheet safety, Immunovant, Inc. (IMVT) carries a lower debt/equity ratio of 0% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — KZR or IMVT or ARQT or INVA or ABBV or JPM or KO?
By revenue growth (latest reported year), Arcutis Biotherapeutics, Inc.
(ARQT) is pulling ahead at 91. 3% versus 1. 9% for The Coca-Cola Company (KO). On earnings-per-share growth, the picture is similar: Innoviva, Inc. grew EPS 816. 7% year-over-year, compared to -566. 1% for Kezar Life Sciences, Inc.. Over a 3-year CAGR, ARQT leads at 367. 3% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — KZR or IMVT or ARQT or INVA or ABBV or JPM or KO?
Innoviva, Inc.
(INVA) is the more profitable company, earning 63. 8% net margin versus -4. 3% for Arcutis Biotherapeutics, Inc. — meaning it keeps 63. 8% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: INVA leads at 38. 5% versus -3. 3% for ARQT. At the gross margin level — before operating expenses — ARQT leads at 90. 2%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is KZR or IMVT or ARQT or INVA or ABBV or JPM or KO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, Innoviva, Inc. (INVA) is the more undervalued stock at a PEG of 0. 62x versus The Coca-Cola Company's 2. 26x. A PEG below 1. 0 is traditionally considered the threshold for growth-adjusted undervaluation. On forward earnings alone, Innoviva, Inc. (INVA) trades at 6. 4x forward P/E versus 122. 5x for Arcutis Biotherapeutics, Inc. — 116. 1x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for INVA: 75. 9% to $40. 00.
08Which pays a better dividend — KZR or IMVT or ARQT or INVA or ABBV or JPM or KO?
In this comparison, ABBV (2.
9% yield), KO (2. 5% yield), JPM (1. 9% yield) pay a dividend. KZR, IMVT, ARQT, INVA do not pay a meaningful dividend and should not be held primarily for income.
09Is KZR or IMVT or ARQT or INVA or ABBV or JPM or KO better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). Immunovant, Inc. (IMVT) carries a higher beta of 1. 66 — meaning larger drawdowns in market downturns, which matters significantly when you cannot wait years for a recovery. Both have compounded well over 10 years (KO: +121. 1%, IMVT: +237. 9%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between KZR and IMVT and ARQT and INVA and ABBV and JPM and KO?
These companies operate in different sectors (KZR (Healthcare) and IMVT (Healthcare) and ARQT (Healthcare) and INVA (Healthcare) and ABBV (Healthcare) and JPM (Financial Services) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: KZR is a small-cap quality compounder stock; IMVT is a small-cap quality compounder stock; ARQT is a small-cap high-growth stock; INVA is a small-cap high-growth stock; ABBV is a large-cap quality compounder stock; JPM is a large-cap deep-value stock; KO is a large-cap quality compounder stock. ABBV, JPM, KO pay a dividend while KZR, IMVT, ARQT, INVA do not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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