Biotechnology
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Side-by-side financial analysisStock Comparison
ZBIO vs JNJ vs KO
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Beverages - Non-Alcoholic
ZBIO vs JNJ vs KO — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | |||
|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Beverages - Non-Alcoholic |
| Market Cap | $793M | $574.35B | $355.22B |
| Revenue (TTM) | $0.00 | $92.15B | $49.28B |
| Net Income (TTM) | $-425M | $25.12B | $13.70B |
| Gross Margin | 100.0% | 68.1% | 61.7% |
| Operating Margin | -21.1% | 26.1% | 29.3% |
| Forward P/E | — | 20.6x | 25.2x |
| Total Debt | $80M | $36.63B | $45.49B |
| Cash & Equiv. | $111M | $24.11B | $10.27B |
ZBIO vs JNJ vs KO — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 24 | Jun 26 | Return |
|---|---|---|---|
| Zenas BioPharma, In… (ZBIO) | 100 | 105.0 | +5.0% |
| Johnson & Johnson (JNJ) | 100 | 147.1 | +47.1% |
| The Coca-Cola Compa… (KO) | 100 | 114.8 | +14.8% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ZBIO vs JNJ vs KO
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ZBIO is the clearest fit if your priority is sleep-well-at-night.
- Lower volatility, beta 1.39, Low D/E 33.0%, current ratio 5.61x
- 100.0% revenue growth vs KO's 1.9%
JNJ has the current edge in this matchup, primarily because of its strength in income & stability and growth exposure.
- Dividend streak 56 yrs, beta 0.03, yield 2.0%
- Rev growth 4.3%, EPS growth -57.8%, 3Y rev CAGR 4.1%
- 140.2% 10Y total return vs KO's 120.9%
KO is the clearest fit if your priority is valuation efficiency.
- PEG 2.26 vs JNJ's 36.63
- 27.8% margin vs ZBIO's -37.8%
- 2.5% yield, 56-year raise streak, vs JNJ's 2.0%, (1 stock pays no dividend)
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 100.0% revenue growth vs KO's 1.9% | |
| Value | Better valuation composite | |
| Quality / Margins | 27.8% margin vs ZBIO's -37.8% | |
| Stability / Safety | Beta 0.03 vs ZBIO's 1.39 | |
| Dividends | 2.5% yield, 56-year raise streak, vs JNJ's 2.0%, (1 stock pays no dividend) | |
| Momentum (1Y) | +56.9% vs KO's +17.4% | |
| Efficiency (ROA) | 13.1% ROA vs ZBIO's -97.4%, ROIC 15.8% vs -154.5% |
ZBIO vs JNJ vs KO — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ZBIO vs JNJ vs KO — Financial Metrics
Side-by-side numbers across 3 stocks — who leads on profitability, valuation, growth, and risk.
Income & Cash Flow (Last 12 Months)
KO leads this category, winning 4 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JNJ and ZBIO operate at a comparable scale, with $92.1B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to ZBIO's -37.8%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | |||
|---|---|---|---|
| RevenueTrailing 12 months | $0 | $92.1B | $49.3B |
| EBITDAEarnings before interest/tax | -$423M | $31.4B | $15.5B |
| Net IncomeAfter-tax profit | -$425M | $25.1B | $13.7B |
| Free Cash FlowCash after capex | -$210M | $19.1B | $12.6B |
| Gross MarginGross profit ÷ Revenue | +100.0% | +68.1% | +61.7% |
| Operating MarginEBIT ÷ Revenue | -21.1% | +26.1% | +29.3% |
| Net MarginNet income ÷ Revenue | -37.8% | +27.3% | +27.8% |
| FCF MarginFCF ÷ Revenue | -17.2% | +20.7% | +25.5% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | +6.8% | +12.1% |
| EPS Growth (YoY)Latest quarter vs prior year | -82.5% | +91.0% | +18.2% |
Valuation Metrics
JNJ leads this category, winning 4 of 7 comparable metrics.
Valuation Metrics
At 27.1x trailing earnings, KO trades at a 34% valuation discount to JNJ's 41.2x P/E. Adjusting for growth (PEG ratio), KO offers better value at 2.43x vs JNJ's 36.63x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | |||
|---|---|---|---|
| Market CapShares × price | $793M | $574.4B | $355.2B |
| Enterprise ValueMkt cap + debt − cash | $762M | $586.9B | $390.4B |
| Trailing P/EPrice ÷ TTM EPS | -2.10x | 41.16x | 27.15x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 20.59x | 25.24x |
| PEG RatioP/E ÷ EPS growth rate | — | 36.63x | 2.43x |
| EV / EBITDAEnterprise value multiple | — | 19.90x | 26.36x |
| Price / SalesMarket cap ÷ Revenue | 79.29x | 6.47x | 7.41x |
| Price / BookPrice ÷ Book value/share | 3.28x | 8.10x | 10.39x |
| Price / FCFMarket cap ÷ FCF | — | 28.95x | 67.07x |
Profitability & Efficiency
Evenly matched — ZBIO and JNJ and KO each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-168 for ZBIO. ZBIO carries lower financial leverage with a 0.33x debt-to-equity ratio, signaling a more conservative balance sheet compared to KO's 1.33x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs ZBIO's 3/9, reflecting strong financial health.
| Metric | |||
|---|---|---|---|
| ROE (TTM)Return on equity | -167.7% | +31.7% | +41.1% |
| ROA (TTM)Return on assets | -97.4% | +13.0% | +13.1% |
| ROICReturn on invested capital | -154.5% | +20.7% | +15.8% |
| ROCEReturn on capital employed | -66.7% | +17.6% | +17.3% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 5 | 7 |
| Debt / EquityFinancial leverage | 0.33x | 0.51x | 1.33x |
| Net DebtTotal debt minus cash | -$31M | $12.5B | $35.2B |
| Cash & Equiv.Liquid assets | $111M | $24.1B | $10.3B |
| Total DebtShort + long-term debt | $80M | $36.6B | $45.5B |
| Interest CoverageEBIT ÷ Interest expense | -62.50x | 48.23x | 10.70x |
Total Returns (Dividends Reinvested)
JNJ leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in KO five years ago would be worth $16,364 today (with dividends reinvested), compared to $9,883 for ZBIO. Over the past 12 months, JNJ leads with a +56.9% total return vs KO's +17.4%. The 3-year compound annual growth rate (CAGR) favors JNJ at 16.6% vs ZBIO's -0.4% — a key indicator of consistent wealth creation.
| Metric | |||
|---|---|---|---|
| YTD ReturnYear-to-date | -48.5% | +16.2% | +20.2% |
| 1-Year ReturnPast 12 months | +46.7% | +56.9% | +17.4% |
| 3-Year ReturnCumulative with dividends | -1.2% | +58.5% | +46.9% |
| 5-Year ReturnCumulative with dividends | -1.2% | +59.0% | +63.6% |
| 10-Year ReturnCumulative with dividends | -1.2% | +140.2% | +120.9% |
| CAGR (3Y)Annualised 3-year return | -0.4% | +16.6% | +13.7% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.15 beta — it tends to amplify market swings less than ZBIO's 1.39 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.2% from its 52-week high vs ZBIO's 39.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | |||
|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.39x | 0.03x | -0.15x |
| 52-Week HighHighest price in past year | $44.60 | $251.71 | $84.04 |
| 52-Week LowLowest price in past year | $8.91 | $149.04 | $65.35 |
| % of 52W HighCurrent price vs 52-week peak | +39.8% | +94.7% | +98.2% |
| RSI (14)Momentum oscillator 0–100 | 45.8 | 63.5 | 65.7 |
| Avg Volume (50D)Average daily shares traded | 530K | 6.3M | 12.6M |
Analyst Outlook
KO leads this category, winning 1 of 1 comparable metric.
Analyst Outlook
Analyst consensus: ZBIO as "Buy", JNJ as "Buy", KO as "Buy". Consensus price targets imply 97.1% upside for ZBIO (target: $35) vs 4.6% for KO (target: $86). For income investors, KO offers the higher dividend yield at 2.47% vs JNJ's 2.04%.
| Metric | |||
|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $35.00 | $250.58 | $86.29 |
| # AnalystsCovering analysts | 5 | 40 | 48 |
| Dividend YieldAnnual dividend ÷ price | — | +2.0% | +2.5% |
| Dividend StreakConsecutive years of raises | — | 56 | 56 |
| Dividend / ShareAnnual DPS | — | $4.87 | $2.04 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | +0.2% |
KO leads in 3 of 6 categories (Income & Cash Flow, Risk & Volatility). JNJ leads in 2 (Valuation Metrics, Total Returns). 1 tied.
ZBIO vs JNJ vs KO: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ZBIO or JNJ or KO a better buy right now?
For growth investors, Zenas BioPharma, Inc.
(ZBIO) is the stronger pick with 100. 0% revenue growth year-over-year, versus 1. 9% for The Coca-Cola Company (KO). The Coca-Cola Company (KO) offers the better valuation at 27. 1x trailing P/E (25. 2x forward), making it the more compelling value choice. Analysts rate Zenas BioPharma, Inc. (ZBIO) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ZBIO or JNJ or KO?
On trailing P/E, The Coca-Cola Company (KO) is the cheapest at 27.
1x versus Johnson & Johnson at 41. 2x. On forward P/E, Johnson & Johnson is actually cheaper at 20. 6x — notably different from the trailing picture, reflecting expected earnings growth. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: The Coca-Cola Company wins at 2. 26x versus Johnson & Johnson's 36. 63x.
03Which is the better long-term investment — ZBIO or JNJ or KO?
Over the past 5 years, The Coca-Cola Company (KO) delivered a total return of +63.
6%, compared to -1. 2% for Zenas BioPharma, Inc. (ZBIO). Over 10 years, the gap is even starker: JNJ returned +140. 2% versus ZBIO's -1. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ZBIO or JNJ or KO?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
15β versus Zenas BioPharma, Inc. 's 1. 39β — meaning ZBIO is approximately -1037% more volatile than KO relative to the S&P 500. On balance sheet safety, Zenas BioPharma, Inc. (ZBIO) carries a lower debt/equity ratio of 33% versus 133% for The Coca-Cola Company — giving it more financial flexibility in a downturn.
05Which is growing faster — ZBIO or JNJ or KO?
By revenue growth (latest reported year), Zenas BioPharma, Inc.
(ZBIO) is pulling ahead at 100. 0% versus 1. 9% for The Coca-Cola Company (KO). On earnings-per-share growth, the picture is similar: The Coca-Cola Company grew EPS 23. 6% year-over-year, compared to -124. 5% for Zenas BioPharma, Inc.. Over a 3-year CAGR, JNJ leads at 4. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ZBIO or JNJ or KO?
The Coca-Cola Company (KO) is the more profitable company, earning 27.
3% net margin versus -37. 8% for Zenas BioPharma, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -21. 1% for ZBIO. At the gross margin level — before operating expenses — ZBIO leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ZBIO or JNJ or KO more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, The Coca-Cola Company (KO) is the more undervalued stock at a PEG of 2. 26x versus Johnson & Johnson's 36. 63x. Both stocks trade at elevated growth-adjusted valuations, so expected growth needs to materialise. On forward earnings alone, Johnson & Johnson (JNJ) trades at 20. 6x forward P/E versus 25. 2x for The Coca-Cola Company — 4. 7x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ZBIO: 97. 1% to $35. 00.
08Which pays a better dividend — ZBIO or JNJ or KO?
In this comparison, KO (2.
5% yield), JNJ (2. 0% yield) pay a dividend. ZBIO does not pay a meaningful dividend and should not be held primarily for income.
09Is ZBIO or JNJ or KO better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
15), 2. 5% yield, +120. 9% 10Y return). Both have compounded well over 10 years (KO: +120. 9%, ZBIO: -1. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ZBIO and JNJ and KO?
These companies operate in different sectors (ZBIO (Healthcare) and JNJ (Healthcare) and KO (Consumer Defensive)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: ZBIO is a small-cap high-growth stock; JNJ is a large-cap quality compounder stock; KO is a large-cap quality compounder stock. JNJ, KO pay a dividend while ZBIO does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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