Biotechnology
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Side-by-side financial analysisStock Comparison
ZBIO vs JNJ vs KO vs JPM
Revenue, margins, valuation, and 5-year total return — side by side.
Drug Manufacturers - General
Beverages - Non-Alcoholic
Banks - Diversified
ZBIO vs JNJ vs KO vs JPM — Key Financials
Market cap, revenue, margins, and valuation side-by-side.
| Company Snapshot | ||||
|---|---|---|---|---|
| Industry | Biotechnology | Drug Manufacturers - General | Beverages - Non-Alcoholic | Banks - Diversified |
| Market Cap | $793M | $574.35B | $355.22B | $875.80B |
| Revenue (TTM) | $0.00 | $92.15B | $49.28B | $280.33B |
| Net Income (TTM) | $-425M | $25.12B | $13.70B | $57.05B |
| Gross Margin | 100.0% | 68.1% | 61.7% | 60.0% |
| Operating Margin | -21.1% | 26.1% | 29.3% | 25.9% |
| Forward P/E | — | 20.8x | 25.2x | 14.1x |
| Total Debt | $80M | $36.63B | $45.49B | $942.38B |
| Cash & Equiv. | $111M | $24.11B | $10.27B | $343.34B |
ZBIO vs JNJ vs KO vs JPM — Long-Term Stock Performance
Price return indexed to 100 at period start. Dividends excluded.
| Stock | Sep 24 | Jun 26 | Return |
|---|---|---|---|
| Zenas BioPharma, In… (ZBIO) | 100 | 117.0 | +17.0% |
| Johnson & Johnson (JNJ) | 100 | 148.6 | +48.6% |
| The Coca-Cola Compa… (KO) | 100 | 115.0 | +15.0% |
| JPMorgan Chase & Co. (JPM) | 100 | 152.1 | +52.1% |
Price return only. Dividends and distributions are not included.
Quick Verdict: ZBIO vs JNJ vs KO vs JPM
Each card shows where this stock fits in a portfolio — not just who wins on paper.
ZBIO is the clearest fit if your priority is growth.
- 100.0% revenue growth vs KO's 1.9%
JNJ is the #2 pick in this set and the best alternative if income & stability and growth exposure is your priority.
- Dividend streak 56 yrs, beta 0.03, yield 2.0%
- Rev growth 4.3%, EPS growth -57.8%, 3Y rev CAGR 4.1%
- Lower volatility, beta 0.03, Low D/E 51.2%, current ratio 1.11x
- Beta 0.03, yield 2.0%, current ratio 1.11x
KO carries the broadest edge in this set and is the clearest fit for quality and dividends.
- 27.8% margin vs ZBIO's -37.8%
- 2.5% yield, 56-year raise streak, vs JPM's 1.9%, (1 stock pays no dividend)
- 13.1% ROA vs ZBIO's -97.4%, ROIC 15.8% vs -154.5%
JPM is the clearest fit if your priority is long-term compounding and valuation efficiency.
- 454.4% 10Y total return vs JNJ's 140.2%
- PEG 1.08 vs JNJ's 37.02
- Lower P/E (14.1x vs 25.2x), PEG 1.08 vs 2.26
See the full category breakdown
| Category | Winner | Why |
|---|---|---|
| Growth | 100.0% revenue growth vs KO's 1.9% | |
| Value | Lower P/E (14.1x vs 25.2x), PEG 1.08 vs 2.26 | |
| Quality / Margins | 27.8% margin vs ZBIO's -37.8% | |
| Stability / Safety | Beta 0.03 vs ZBIO's 1.39 | |
| Dividends | 2.5% yield, 56-year raise streak, vs JPM's 1.9%, (1 stock pays no dividend) | |
| Momentum (1Y) | +56.9% vs KO's +17.4% | |
| Efficiency (ROA) | 13.1% ROA vs ZBIO's -97.4%, ROIC 15.8% vs -154.5% |
ZBIO vs JNJ vs KO vs JPM — Revenue Breakdown by Segment
How each company's revenue is distributed across its business units
Segment breakdown not available.
ZBIO vs JNJ vs KO vs JPM — Financial Metrics
Side-by-side numbers across 4 stocks — who leads on profitability, valuation, growth, and risk.
Who Leads Where
KO leads in 3 of 6 categories
JPM leads 2 • ZBIO leads 0 • JNJ leads 0 • 1 tied
Explore the data ↓Income & Cash Flow (Last 12 Months)
KO leads this category, winning 3 of 6 comparable metrics.
Income & Cash Flow (Last 12 Months)
JPM and ZBIO operate at a comparable scale, with $280.3B and $0 in trailing revenue. KO is the more profitable business, keeping 27.8% of every revenue dollar as net income compared to ZBIO's -37.8%. On growth, KO holds the edge at +12.1% YoY revenue growth, suggesting stronger near-term business momentum.
| Metric | ||||
|---|---|---|---|---|
| RevenueTrailing 12 months | $0 | $92.1B | $49.3B | $280.3B |
| EBITDAEarnings before interest/tax | -$423M | $31.4B | $15.5B | $81.4B |
| Net IncomeAfter-tax profit | -$425M | $25.1B | $13.7B | $57.0B |
| Free Cash FlowCash after capex | -$210M | $19.1B | $12.6B | $100.9B |
| Gross MarginGross profit ÷ Revenue | +100.0% | +68.1% | +61.7% | +60.0% |
| Operating MarginEBIT ÷ Revenue | -21.1% | +26.1% | +29.3% | +25.9% |
| Net MarginNet income ÷ Revenue | -37.8% | +27.3% | +27.8% | +20.4% |
| FCF MarginFCF ÷ Revenue | -17.2% | +20.7% | +25.5% | +36.0% |
| Rev. Growth (YoY)Latest quarter vs prior year | -100.0% | +6.8% | +12.1% | — |
| EPS Growth (YoY)Latest quarter vs prior year | -82.5% | +91.0% | +18.2% | +16.0% |
Valuation Metrics
JPM leads this category, winning 6 of 7 comparable metrics.
Valuation Metrics
At 15.6x trailing earnings, JPM trades at a 62% valuation discount to JNJ's 41.2x P/E. Adjusting for growth (PEG ratio), JPM offers better value at 1.20x vs JNJ's 37.02x — a lower PEG means you pay less per unit of expected earnings growth.
| Metric | ||||
|---|---|---|---|---|
| Market CapShares × price | $793M | $574.4B | $355.2B | $875.8B |
| Enterprise ValueMkt cap + debt − cash | $762M | $586.9B | $390.4B | $1.47T |
| Trailing P/EPrice ÷ TTM EPS | -2.10x | 41.16x | 27.15x | 15.64x |
| Forward P/EPrice ÷ next-FY EPS est. | — | 20.81x | 25.24x | 14.08x |
| PEG RatioP/E ÷ EPS growth rate | — | 37.02x | 2.43x | 1.20x |
| EV / EBITDAEnterprise value multiple | — | 19.90x | 26.36x | 18.11x |
| Price / SalesMarket cap ÷ Revenue | 79.29x | 6.47x | 7.41x | 3.13x |
| Price / BookPrice ÷ Book value/share | 3.28x | 8.10x | 10.39x | 2.42x |
| Price / FCFMarket cap ÷ FCF | — | 28.95x | 67.07x | 8.68x |
Profitability & Efficiency
Evenly matched — ZBIO and JNJ and KO each lead in 3 of 9 comparable metrics.
Profitability & Efficiency
KO delivers a 41.1% return on equity — every $100 of shareholder capital generates $41 in annual profit, vs $-168 for ZBIO. ZBIO carries lower financial leverage with a 0.33x debt-to-equity ratio, signaling a more conservative balance sheet compared to JPM's 2.60x. On the Piotroski fundamental quality scale (0–9), KO scores 7/9 vs ZBIO's 3/9, reflecting strong financial health.
| Metric | ||||
|---|---|---|---|---|
| ROE (TTM)Return on equity | -167.7% | +31.7% | +41.1% | +15.9% |
| ROA (TTM)Return on assets | -97.4% | +13.0% | +13.1% | +1.3% |
| ROICReturn on invested capital | -154.5% | +20.7% | +15.8% | +4.5% |
| ROCEReturn on capital employed | -66.7% | +17.6% | +17.3% | +8.9% |
| Piotroski ScoreFundamental quality 0–9 | 3 | 5 | 7 | 5 |
| Debt / EquityFinancial leverage | 0.33x | 0.51x | 1.33x | 2.60x |
| Net DebtTotal debt minus cash | -$31M | $12.5B | $35.2B | $599.0B |
| Cash & Equiv.Liquid assets | $111M | $24.1B | $10.3B | $343.3B |
| Total DebtShort + long-term debt | $80M | $36.6B | $45.5B | $942.4B |
| Interest CoverageEBIT ÷ Interest expense | -62.50x | 48.23x | 10.70x | 0.74x |
Total Returns (Dividends Reinvested)
JPM leads this category, winning 4 of 6 comparable metrics.
Total Returns (Dividends Reinvested)
A $10,000 investment in JPM five years ago would be worth $20,999 today (with dividends reinvested), compared to $9,883 for ZBIO. Over the past 12 months, JNJ leads with a +56.9% total return vs KO's +17.4%. The 3-year compound annual growth rate (CAGR) favors JPM at 32.6% vs ZBIO's -0.4% — a key indicator of consistent wealth creation.
| Metric | ||||
|---|---|---|---|---|
| YTD ReturnYear-to-date | -48.5% | +16.2% | +20.2% | -2.8% |
| 1-Year ReturnPast 12 months | +46.7% | +56.9% | +17.4% | +19.1% |
| 3-Year ReturnCumulative with dividends | -1.2% | +58.5% | +46.9% | +133.1% |
| 5-Year ReturnCumulative with dividends | -1.2% | +59.0% | +63.6% | +110.0% |
| 10-Year ReturnCumulative with dividends | -1.2% | +140.2% | +120.9% | +454.4% |
| CAGR (3Y)Annualised 3-year return | -0.4% | +16.6% | +13.7% | +32.6% |
Risk & Volatility
KO leads this category, winning 2 of 2 comparable metrics.
Risk & Volatility
KO is the less volatile stock with a -0.15 beta — it tends to amplify market swings less than ZBIO's 1.39 beta. A beta below 1.0 means the stock typically moves less than the S&P 500. KO currently trades 98.2% from its 52-week high vs ZBIO's 39.8% drawdown — a narrower gap to the peak suggests stronger recent price momentum.
| Metric | ||||
|---|---|---|---|---|
| Beta (5Y)Sensitivity to S&P 500 | 1.31x | 0.01x | -0.20x | 0.94x |
| 52-Week HighHighest price in past year | $44.60 | $251.71 | $84.04 | $337.25 |
| 52-Week LowLowest price in past year | $8.91 | $149.04 | $65.35 | $262.71 |
| % of 52W HighCurrent price vs 52-week peak | +39.8% | +94.7% | +98.2% | +93.0% |
| RSI (14)Momentum oscillator 0–100 | 45.8 | 63.5 | 65.7 | 54.8 |
| Avg Volume (50D)Average daily shares traded | 530K | 6.3M | 12.6M | 7.0M |
Analyst Outlook
KO leads this category, winning 2 of 2 comparable metrics.
Analyst Outlook
Analyst consensus: ZBIO as "Buy", JNJ as "Buy", KO as "Buy", JPM as "Buy". Consensus price targets imply 97.1% upside for ZBIO (target: $35) vs 4.6% for KO (target: $86). For income investors, KO offers the higher dividend yield at 2.47% vs JPM's 1.90%.
| Metric | ||||
|---|---|---|---|---|
| Analyst RatingConsensus buy/hold/sell | Buy | Buy | Buy | Buy |
| Price TargetConsensus 12-month target | $35.00 | $251.55 | $86.29 | $338.78 |
| # AnalystsCovering analysts | 5 | 40 | 48 | 61 |
| Dividend YieldAnnual dividend ÷ price | — | +2.0% | +2.5% | +1.9% |
| Dividend StreakConsecutive years of raises | — | 56 | 56 | 15 |
| Dividend / ShareAnnual DPS | — | $4.87 | $2.04 | $5.95 |
| Buyback YieldShare repurchases ÷ mkt cap | 0.0% | +0.4% | +0.2% | +3.9% |
KO leads in 3 of 6 categories (Income & Cash Flow, Risk & Volatility). JPM leads in 2 (Valuation Metrics, Total Returns). 1 tied.
ZBIO vs JNJ vs KO vs JPM: Key Questions Answered
10 questions · data-driven answers · updated daily
01Is ZBIO or JNJ or KO or JPM a better buy right now?
For growth investors, Zenas BioPharma, Inc.
(ZBIO) is the stronger pick with 100. 0% revenue growth year-over-year, versus 1. 9% for The Coca-Cola Company (KO). JPMorgan Chase & Co. (JPM) offers the better valuation at 15. 6x trailing P/E (14. 1x forward), making it the more compelling value choice. Analysts rate Zenas BioPharma, Inc. (ZBIO) a "Buy" — based on 5 analyst ratings — the highest consensus in this comparison. The "better buy" depends entirely on your goals: growth investors should weight revenue trajectory, value investors should weight P/E and PEG, and income investors should weight dividend yield and streak.
02Which has the better valuation — ZBIO or JNJ or KO or JPM?
On trailing P/E, JPMorgan Chase & Co.
(JPM) is the cheapest at 15. 6x versus Johnson & Johnson at 41. 2x. On forward P/E, JPMorgan Chase & Co. is actually cheaper at 14. 1x. The PEG ratio (P/E divided by earnings growth rate) is the most growth-adjusted single valuation metric: JPMorgan Chase & Co. wins at 1. 08x versus Johnson & Johnson's 37. 02x — a reasonable growth-adjusted valuation.
03Which is the better long-term investment — ZBIO or JNJ or KO or JPM?
Over the past 5 years, JPMorgan Chase & Co.
(JPM) delivered a total return of +110. 0%, compared to -1. 2% for Zenas BioPharma, Inc. (ZBIO). Over 10 years, the gap is even starker: JPM returned +465. 8% versus ZBIO's +10. 2%. Past returns do not guarantee future results, and the stock with the higher historical return may already have its best growth priced in.
04Which is safer — ZBIO or JNJ or KO or JPM?
By beta (market sensitivity over 5 years), The Coca-Cola Company (KO) is the lower-risk stock at -0.
20β versus Zenas BioPharma, Inc. 's 1. 31β — meaning ZBIO is approximately -756% more volatile than KO relative to the S&P 500. On balance sheet safety, Zenas BioPharma, Inc. (ZBIO) carries a lower debt/equity ratio of 33% versus 3% for JPMorgan Chase & Co. — giving it more financial flexibility in a downturn.
05Which is growing faster — ZBIO or JNJ or KO or JPM?
By revenue growth (latest reported year), Zenas BioPharma, Inc.
(ZBIO) is pulling ahead at 100. 0% versus 1. 9% for The Coca-Cola Company (KO). On earnings-per-share growth, the picture is similar: The Coca-Cola Company grew EPS 23. 6% year-over-year, compared to -124. 5% for Zenas BioPharma, Inc.. Over a 3-year CAGR, JNJ leads at 4. 1% annualised revenue growth. Higher growth typically commands a higher valuation multiple — check whether the premium P/E or P/S is justified by the growth rate using the PEG ratio.
06Which has better profit margins — ZBIO or JNJ or KO or JPM?
The Coca-Cola Company (KO) is the more profitable company, earning 27.
3% net margin versus -37. 8% for Zenas BioPharma, Inc. — meaning it keeps 27. 3% of every revenue dollar as bottom-line profit. Operating margin tells a similar story: KO leads at 28. 7% versus -21. 1% for ZBIO. At the gross margin level — before operating expenses — ZBIO leads at 100. 0%, reflecting greater pricing power or product mix advantage. Stronger margins indicate durable pricing power, lower cost of revenue, or higher mix of software/services. They are one of the clearest signs of business quality.
07Is ZBIO or JNJ or KO or JPM more undervalued right now?
The PEG ratio (forward P/E divided by expected earnings growth rate) is the most precise measure of undervaluation relative to growth potential.
By this metric, JPMorgan Chase & Co. (JPM) is the more undervalued stock at a PEG of 1. 08x versus Johnson & Johnson's 37. 02x. A PEG below 1. 5 suggests fair-to-attractive pricing relative to expected growth. On forward earnings alone, JPMorgan Chase & Co. (JPM) trades at 14. 1x forward P/E versus 25. 2x for The Coca-Cola Company — 11. 2x cheaper on a one-year earnings basis. Analyst consensus price targets imply the most upside for ZBIO: 97. 1% to $35. 00.
08Which pays a better dividend — ZBIO or JNJ or KO or JPM?
In this comparison, KO (2.
5% yield), JNJ (2. 0% yield), JPM (1. 9% yield) pay a dividend. ZBIO does not pay a meaningful dividend and should not be held primarily for income.
09Is ZBIO or JNJ or KO or JPM better for a retirement portfolio?
For long-horizon retirement investors, The Coca-Cola Company (KO) is the stronger choice — it scores higher on the combination of lower volatility, dividend reliability, and long-term compounding (low volatility (β -0.
20), 2. 5% yield, +121. 1% 10Y return). Both have compounded well over 10 years (KO: +121. 1%, ZBIO: +10. 2%), confirming both are viable long-term holds — but the lower-volatility option typically results in less emotional selling during corrections. Retirement portfolios generally favour predictability over maximum returns. Consult a financial advisor before making allocation decisions.
10What are the main differences between ZBIO and JNJ and KO and JPM?
These companies operate in different sectors (ZBIO (Healthcare) and JNJ (Healthcare) and KO (Consumer Defensive) and JPM (Financial Services)), which means they face different economic cycles, regulatory environments, and macro sensitivities — making direct comparison nuanced.
In terms of investment character: ZBIO is a small-cap high-growth stock; JNJ is a large-cap quality compounder stock; KO is a large-cap quality compounder stock; JPM is a large-cap deep-value stock. JNJ, KO, JPM pay a dividend while ZBIO does not, making them suitable for different income and tax situations. These fundamental differences mean investors should not choose between them on a single metric — the "better stock" depends entirely on which of these characteristics aligns with your investment strategy.
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