AC Immune S.A. (ACIU) fundamental analysis — strengths, weaknesses & financial health based on data analysis
No significant strengths identified
* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.
AC Immune S.A. (ACIU) stock price & volume — 10-year historical chart
AC Immune S.A. (ACIU) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR
AC Immune S.A. (ACIU) EPS & revenue vs analyst estimates — last 4 quarters
| Quarter | Date | EPS (Act vs Est) | Revenue (Act vs Est) |
|---|---|---|---|
| Q2 2026Latest | Apr 29, 2026 | $0.19vs $0.20+5.0% | $1Mvs $329,435+325.0% |
| Q2 2026 | Mar 13, 2026 | $0.18vs $0.19+5.3% | $426,353vs $1M-70.5% |
| Q4 2025 | Nov 4, 2025 | $0.20vs $0.22+9.1% | $1Mvs $1M+3.2% |
| Q3 2025 | Aug 5, 2025 | $0.25vs $0.20-25.0% | $2Mvs $315,780+420.5% |
AC Immune S.A. (ACIU) competitors in Neuroscience and Psychiatry Therapies — business model, growth, and fundamentals comparison
AC Immune S.A. (ACIU) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.
AC Immune S.A. (ACIU) annual income statement — 10-year revenue, gross profit & net income history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 20.25M | 7.19M | 110.46M | 15.43M | 0 | 3.94M | 14.8M | 27.31M | 3.57M |
| Revenue Growth % | -12.75% | -64.48% | 1435.39% | -86.03% | -100% | - | 276.14% | 84.51% | -86.92% |
| Cost of Goods Sold | 32.66M | 44.28M | 50.43M | 59.49M | 0 | 0 | 54.61M | 62.57M | 0 |
| COGS % of Revenue | 161.26% | 615.47% | 45.66% | 385.5% | - | - | 368.93% | 229.12% | - |
| Gross Profit | -12.41M▲ 0% | -37.08M▼ 198.9% | 60.02M▲ 261.9% | -44.06M▼ 173.4% | 0▲ 100.0% | 3.94M▲ 0% | -39.8M▼ 1111.6% | -35.26M▲ 11.4% | 3.57M▲ 110.1% |
| Gross Margin % | -61.26% | -515.47% | 54.34% | -285.5% | - | 100% | -268.93% | -129.12% | 100% |
| Gross Profit Growth % | -384.69% | -198.86% | 261.86% | -173.4% | 100% | - | -1111.56% | 11.42% | 110.13% |
| Operating Expenses | 42.79M | 56.74M | 15.49M | 17.2M | 79.01M | 74.78M | 13.82M | 17.12M | 72.44M |
| OpEx % of Revenue | 211.28% | 788.77% | 14.02% | 111.49% | - | 1900.43% | 93.37% | 62.68% | 2027.32% |
| Selling, General & Admin | 6.27M | 7.56M | 16.06M | 18.56M | 10.88M | 9.58M | 10.58M | 11.43M | 11.65M |
| SG&A % of Revenue | 30.98% | 105.14% | 14.54% | 120.26% | - | 243.51% | 71.45% | 41.87% | 326.11% |
| Research & Development | 32.66M | 44.28M | 50.43M | 59.49M | 62.28M | 60.34M | 54.61M | 62.57M | 56.44M |
| R&D % of Revenue | 161.26% | 615.47% | 45.66% | 385.5% | - | 1533.32% | 368.93% | 229.12% | 1579.51% |
| Other Operating Expenses | 3.86M | 4.9M | -51M | -60.84M | 5.85M | 4.86M | -51.36M | -56.89M | 4.35M |
| Operating Income | -22.54M▲ 0% | -49.55M▼ 119.8% | 44.54M▲ 189.9% | -61.26M▼ 237.6% | -79.01M▼ 29.0% | -70.85M▲ 10.3% | -53.62M▲ 24.3% | -52.38M▲ 2.3% | -68.86M▼ 31.5% |
| Operating Margin % | -111.28% | -688.77% | 40.32% | -396.99% | - | -1800.43% | -362.3% | -191.8% | -1927.32% |
| Operating Income Growth % | -115.56% | -119.84% | 189.88% | -237.55% | -28.97% | 10.33% | 24.31% | 2.32% | -31.47% |
| EBITDA | -21.96M | -48.59M | 45.81M | -59.73M | -76.6M | -68.49M | -51.41M | -50.22M | -66.36M |
| EBITDA Margin % | -108.41% | -675.41% | 41.47% | -387.05% | - | -1740.48% | -347.33% | -183.88% | -1857.26% |
| EBITDA Growth % | -115.75% | -121.27% | 194.28% | -230.38% | -28.26% | 10.59% | 24.94% | 2.32% | -32.15% |
| D&A (Non-Cash Add-back) | 580K | 961K | 1.27M | 1.53M | 2.41M | 2.36M | 2.21M | 2.16M | 2.5M |
| EBIT | -26.26M | -50.62M | 44.54M | -61.26M | -72.41M | -70.39M | -54.05M | -50.78M | -70.26M |
| Net Interest Income | 176K | -207K | -1.62M | -106K | 5.9M | -286K | 868K | 3.06M | 1.67M |
| Interest Income | 330K | 127K | 303K | 78K | 6.49M | 69K | 1.04M | 3.2M | 1.86M |
| Interest Expense | 147K | 334K | 1.93M | 184K | 581K | 355K | 176K | 133K | 191K |
| Other Income/Expense | -3.87M | -1.4M | 906K | -661K | 6.02M | 107K | -599K | 1.47M | -1.58M |
| Pretax Income | -26.41M▲ 0% | -50.95M▼ 92.9% | 45.44M▲ 189.2% | -61.92M▼ 236.3% | -72.99M▼ 17.9% | -70.74M▲ 3.1% | -54.22M▲ 23.3% | -50.91M▲ 6.1% | -70.45M▼ 38.4% |
| Pretax Margin % | -130.39% | -708.24% | 41.14% | -401.28% | - | -1797.71% | -366.35% | -186.43% | -1971.65% |
| Income Tax | 147K | 0 | 0 | 0 | 3K | 13K | 10K | 3K | 0 |
| Effective Tax Rate % | -0.56% | 0% | 0% | 0% | -0% | -0.02% | -0.02% | -0.01% | 0% |
| Net Income | -26.41M▲ 0% | -50.95M▼ 92.9% | 45.44M▲ 189.2% | -61.92M▼ 236.3% | -73M▼ 17.9% | -70.75M▲ 3.1% | -54.23M▲ 23.3% | -50.92M▲ 6.1% | -70.45M▼ 38.4% |
| Net Margin % | -130.39% | -708.24% | 41.14% | -401.28% | - | -1798.04% | -366.41% | -186.44% | -1971.65% |
| Net Income Growth % | -272.2% | -92.92% | 189.19% | -236.26% | -17.89% | 3.07% | 23.35% | 6.12% | -38.36% |
| Net Income (Continuing) | -26.41M | -50.95M | 45.44M | -61.92M | -73M | -70.75M | -54.23M | -50.92M | -70.45M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.46▲ 0% | -0.82▼ 78.3% | 0.64▲ 178.0% | -0.86▼ 234.4% | -0.97▼ 12.8% | -0.85▲ 12.4% | -0.64▲ 24.7% | -0.51▲ 20.3% | -0.70▼ 37.3% |
| EPS Growth % | -228.57% | -78.26% | 178.05% | -234.38% | -12.79% | 12.37% | 24.71% | 20.31% | -37.25% |
| EPS (Basic) | -0.46 | -0.82 | 0.64 | -0.86 | -0.97 | -0.85 | -0.64 | -0.51 | -0.70 |
| Diluted Shares Outstanding | 57.36M | 61.84M | 71.1M | 71.9M | 74.95M | 83.55M | 84.69M | 99.69M | 100.75M |
| Basic Shares Outstanding | 57.08M | 61.84M | 70.6M | 71.9M | 74.95M | 83.55M | 84.69M | 99.69M | 100.75M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - |
AC Immune S.A. (ACIU) balance sheet — assets, liabilities & shareholders' equity
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 129.53M | 192.93M | 292.77M | 231.77M | 202.63M | 128.09M | 125.15M | 171.99M | 96.83M |
| Cash & Short-Term Investments | 124.38M | 186.46M | 288.59M | 225.89M | 198.22M | 122.59M | 103.05M | 165.49M | 91.52M |
| Cash Only | 124.38M | 156.46M | 193.59M | 160.89M | 82.22M | 31.59M | 78.49M | 36.27M | 26.83M |
| Short-Term Investments | 0 | 30M | 95M | 65M | 116M | 91M | 24.55M | 129.21M | 64.69M |
| Accounts Receivable | 3.72M | 4.1M | 1.4M | 1.59M | 975K | 408K | 15.05M | 1.1M | 681.77K |
| Days Sales Outstanding | 66.98 | 208.12 | 4.62 | 37.63 | - | 37.84 | 371.04 | 14.69 | 69.65 |
| Inventory | -1.36M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Days Inventory Outstanding | - | - | - | - | - | - | - | - | - |
| Other Current Assets | 0 | 0 | 0 | 329K | 428K | 392K | 622K | 1.1M | 0 |
| Total Non-Current Assets | 2.48M | 3.63M | 6.48M | 6.97M | 58.81M | 57.84M | 57.66M | 58.92M | 57.59M |
| Property, Plant & Equipment | 2.35M | 3.32M | 6.17M | 6.64M | 8.03M | 7.07M | 6.88M | 8.09M | 6.54M |
| Fixed Asset Turnover | 8.61x | 2.16x | 17.90x | 2.32x | - | 0.56x | 2.15x | 3.38x | 0.55x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 50.42M | 50.42M | 50.42M | 50.42M | 50.47M |
| Long-Term Investments | 126K | 304K | 304K | 0 | 0 | 0 | 361K | 0 | 584.66K |
| Other Non-Current Assets | 0 | 0 | 0 | 334K | 363K | 361K | 0 | 415K | 0 |
| Total Assets | 132.01M▲ 0% | 196.56M▲ 48.9% | 299.25M▲ 52.2% | 238.74M▼ 20.2% | 261.44M▲ 9.5% | 185.94M▼ 28.9% | 182.81M▼ 1.7% | 230.91M▲ 26.3% | 154.43M▼ 33.1% |
| Asset Turnover | 0.15x | 0.04x | 0.37x | 0.06x | - | 0.02x | 0.08x | 0.12x | 0.02x |
| Asset Growth % | -15.43% | 48.89% | 52.25% | -20.22% | 9.51% | -28.88% | -1.68% | 26.31% | -33.12% |
| Total Current Liabilities | 9.75M | 13.08M | 17.51M | 14.02M | 20.03M | 11.48M | 13.58M | 100.84M | 94.8M |
| Accounts Payable | 1.09M | 1.98M | 142K | 2.18M | 2M | 929K | 1.68M | 2.66M | 2.07M |
| Days Payables Outstanding | 12.2 | 16.31 | 1.03 | 13.4 | - | - | 11.22 | 15.51 | - |
| Short-Term Debt | 0 | 332K | 652K | 0 | 0 | 0 | 0 | 0 | 852.97K |
| Deferred Revenue (Current) | 355K | 351K | 4.48M | 0 | 0 | 0 | 138K | 0 | 83.8M |
| Other Current Liabilities | 0 | 0 | 0 | 306K | 717K | 587K | 0 | 85.06M | 3.83M |
| Current Ratio | 13.28x | 14.75x | 16.72x | 16.53x | 10.12x | 11.16x | 9.22x | 1.71x | 1.02x |
| Quick Ratio | 13.42x | 14.75x | 16.72x | 16.53x | 10.12x | 11.16x | 9.22x | 1.71x | 1.02x |
| Cash Conversion Cycle | - | - | - | - | - | - | - | - | - |
| Total Non-Current Liabilities | 5.42M | 5.85M | 9.3M | 9.24M | 9.44M | 5.47M | 8.6M | 17.8M | 14.69M |
| Long-Term Debt | 494K | 186K | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Capital Lease Obligations | 395K | 0 | 1.81M | 1.78M | 2.34M | 2.25M | 2.83M | 4.4M | 3.69M |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 4.53M | 5.67M | 7.49M | 7.46M | 7.1M | 3.21M | 5.77M | 13.4M | 8.66M |
| Total Liabilities | 15.17M | 18.93M | 26.81M | 23.26M | 29.46M | 16.95M | 22.17M | 118.64M | 109.49M |
| Total Debt | 395K | 518K | 2.91M | 2.22M | 2.91M | 2.8M | 3.5M | 5.43M | 4.55M |
| Net Debt | -123.98M | -155.94M | -190.68M | -158.67M | -79.31M | -28.79M | -75M | -30.85M | -22.28M |
| Debt / Equity | 0.00x | 0.00x | 0.01x | 0.01x | 0.01x | 0.02x | 0.02x | 0.05x | 0.10x |
| Debt / EBITDA | - | - | 0.06x | - | - | - | - | - | - |
| Net Debt / EBITDA | - | - | -4.16x | - | - | - | - | - | - |
| Interest Coverage | -178.67x | -151.55x | 23.12x | -332.93x | -124.63x | -198.27x | -307.09x | -381.80x | -367.83x |
| Total Equity | 116.84M▲ 0% | 177.62M▲ 52.0% | 272.44M▲ 53.4% | 215.48M▼ 20.9% | 231.98M▲ 7.7% | 168.99M▼ 27.2% | 160.64M▼ 4.9% | 112.27M▼ 30.1% | 44.93M▼ 60.0% |
| Equity Growth % | -17.94% | 52.02% | 53.38% | -20.91% | 7.66% | -27.15% | -4.94% | -30.11% | -59.98% |
| Book Value per Share | 2.04 | 2.87 | 3.83 | 3.00 | 3.10 | 2.02 | 1.90 | 1.13 | 0.45 |
| Total Shareholders' Equity | 116.84M | 177.62M | 272.44M | 215.48M | 231.98M | 168.99M | 160.64M | 112.27M | 44.93M |
| Common Stock | 1.15M | 1.35M | 1.44M | 1.54M | 1.79M | 1.8M | 2.09M | 2.23M | 2.26M |
| Retained Earnings | -72.61M | -121.88M | -75.52M | -132.85M | -200.94M | -264.01M | -316.2M | -368.24M | -439.52M |
| Treasury Stock | 0 | 0 | 0 | -100K | -124K | -124K | -105K | -218K | -218.25K |
| Accumulated OCI | 179.35M | -3.54M | 0 | 0 | 0 | 10K | -51K | -5K | 7.01K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
AC Immune S.A. (ACIU) cash flow — operating, investing & free cash flow history
| Line item | Dec'17 | Dec'18 | Dec'19 | Dec'20 | Dec'21 | Dec'22 | Dec'23 | Dec'24 | Dec'25 |
|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -22.09M | -44.08M | 55.22M | -59.52M | -65.69M | -73.57M | -60.41M | 65.84M | -66.15M |
| Operating CF Margin % | -109.08% | -612.7% | 49.99% | -385.7% | - | -1869.58% | -408.13% | 241.1% | -1851.33% |
| Operating CF Growth % | -291.32% | -99.5% | 225.28% | -207.78% | -10.37% | -11.99% | 17.89% | 209% | -200.46% |
| Net Income | -26.41M | -50.95M | 45.44M | -61.92M | -73M | -70.75M | -54.23M | -50.92M | -67.28M |
| Depreciation & Amortization | 580K | 961K | 1.69M | 1.97M | 2.41M | 2.36M | 2.21M | 2.16M | 2.39M |
| Stock-Based Compensation | 1.58M | 2.52M | 2.83M | 4.09M | 4.13M | 3.33M | 4.37M | 5.47M | 0 |
| Deferred Taxes | 177K | 131K | 0 | 0 | 130K | 0 | 0 | 0 | 0 |
| Other Non-Cash Items | 3.97M | 1.45M | -400K | 922K | -6.2M | -72K | 2.4M | 1.61M | 5.21M |
| Working Capital Changes | -1.99M | 1.81M | 5.65M | -4.57M | 6.84M | -8.43M | -15.16M | 107.51M | -6.47M |
| Change in Receivables | -401K | 698K | 2.5M | -532K | -99K | 603K | -14.8M | 13.55M | 877.68K |
| Change in Inventory | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Change in Payables | -2.85M | 0 | 0 | 0 | 0 | 0 | 0 | 0 | -565.38K |
| Cash from Investing | -1.84M | -32.04M | -66.89M | 28.33M | -53.66M | 23.76M | 65.64M | -105.29M | 60.69M |
| Capital Expenditures | -1.8M | -1.86M | -1.89M | -1.71M | -2.63M | -1.24M | -801K | -576K | -859.54K |
| CapEx % of Revenue | 8.9% | 25.83% | 1.71% | 11.06% | - | 31.49% | 5.41% | 2.11% | 24.06% |
| Acquisitions | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 14.32K |
| Investments | - | - | - | - | - | - | - | - | - |
| Other Investing | -40K | -178K | 0 | 30.04M | -51.03M | 25M | 66.45M | -104.71M | -162.36K |
| Cash from Financing | 271K | 109.38M | 49.62M | -803K | 40.75M | -1.35M | 43.25M | -1.12M | -974.14K |
| Debt Issued (Net) | 200K | 198K | 50.06M | -946K | 22.95M | -569K | -548K | -683K | -1.03M |
| Equity Issued (Net) | 0 | 111.53M | 0 | 0 | 17.8M | -1K | 43.8M | 111K | 5.73K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | 0 | 0 | 0 | -100K | 0 | -8K | 0 | 0 | 0 |
| Other Financing | 71K | -2.35M | -441K | 143K | -6K | -776K | 0 | -548K | 46.13K |
| Net Change in Cash | -27.83M▲ 0% | 32.09M▲ 215.3% | 37.13M▲ 15.7% | -32.69M▼ 188.1% | -78.68M▼ 140.6% | -50.63M▲ 35.6% | 46.91M▲ 192.6% | -42.22M▼ 190.0% | -4.92M▲ 88.3% |
| Free Cash Flow | -23.9M▲ 0% | -45.94M▼ 92.2% | 53.34M▲ 216.1% | -61.22M▼ 214.8% | -68.32M▼ 11.6% | -74.81M▼ 9.5% | -61.21M▲ 18.2% | 65.27M▲ 206.6% | -67.01M▼ 202.7% |
| FCF Margin % | -117.98% | -638.53% | 48.29% | -396.75% | - | -1901.07% | -413.55% | 238.99% | -1875.39% |
| FCF Growth % | -265.1% | -92.23% | 216.11% | -214.79% | -11.6% | -9.49% | 18.18% | 206.63% | -202.67% |
| FCF per Share | -0.42 | -0.74 | 0.75 | -0.85 | -0.91 | -0.90 | -0.72 | 0.65 | -0.67 |
| FCF Conversion (FCF/Net Income) | 0.84x | 0.87x | 1.22x | 0.96x | 0.90x | 1.04x | 1.11x | -1.29x | 0.94x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
AC Immune S.A. (ACIU) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -6.65% | -20.38% | -34.61% | 20.19% | -25.38% | -32.63% | -35.29% | -32.91% | -37.31% | -89.62% |
| Return on Invested Capital (ROIC) | - | - | -511.32% | 64.58% | -66.31% | -56.58% | -36.28% | -35.61% | -47.03% | -99.25% |
| Gross Margin | -11.03% | -61.26% | -515.47% | 54.34% | -285.5% | - | 100% | -268.93% | -129.12% | 100% |
| Net Margin | -30.57% | -130.39% | -708.24% | 41.14% | -401.28% | - | -1798.04% | -366.41% | -186.44% | -1971.65% |
| Debt / Equity | - | 0.00x | 0.00x | 0.01x | 0.01x | 0.01x | 0.02x | 0.02x | 0.05x | 0.10x |
| Interest Coverage | -27.69x | -178.67x | -151.55x | 23.12x | -332.93x | -124.63x | -198.27x | -307.09x | -381.80x | -367.83x |
| FCF Conversion | 0.80x | 0.84x | 0.87x | 1.22x | 0.96x | 0.90x | 1.04x | 1.11x | -1.29x | 0.94x |
| Revenue Growth | -40.61% | -12.75% | -64.48% | 1435.39% | -86.03% | -100% | - | 276.14% | 84.51% | -86.92% |
AC Immune S.A. (ACIU) stock FAQ — growth, dividends, profitability & financials explained
AC Immune S.A. (ACIU) reported $3.6M in revenue for fiscal year 2025. This represents a 59% decrease from $8.6M in 2013.
AC Immune S.A. (ACIU) saw revenue decline by 86.9% over the past year.
AC Immune S.A. (ACIU) reported a net loss of $70.3M for fiscal year 2025.
AC Immune S.A. (ACIU) has a return on equity (ROE) of -89.6%. Negative ROE indicates the company is unprofitable.
AC Immune S.A. (ACIU) had negative free cash flow of $70.1M in fiscal year 2025, likely due to heavy capital investments.
AC Immune S.A. (ACIU) financial analysis — history, returns, DCA and operating performance tools
Historical returns with dividends reinvested
Dollar cost averaging vs lump sum
Yield, growth, payout safety & DRIP
EPS trends, net income & profitability
Long-term charts & historical price data
Sales growth patterns & revenue breakdown
30 years of market, efficiency and balance-sheet ratios
DCF intrinsic value, peer multiples & estimates