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CLNN logoClene Inc.(CLNN)Earnings, Financials & Key Ratios

CLNN•NASDAQ
$7.16
$72M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutClene Inc., a clinical-stage pharmaceutical company, focuses on the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. Its lead drug is CNM-Au8, which is being studied in various clinical trials, including a Phase 2/3 registrational clinical trial for patients with amyotrophic lateral sclerosis (ALS); completed Phase 2 proof of concept clinical trial in patients with early symptomatic ALS; completed two open-label investigator blinded Phase 2 clinical trials on the brain's energy metabolites; ongoing Phase 2 clinical trial for the treatment of visual pathway deficits in chronic optic neuropathy for remyelination in stable relapsing Multiple Sclerosis; and a planned Phase 2 clinical trial for the treatment of patients with Parkinson's Diseases. The company's products also include CNM-AgZn17, a gel polymer suspension of silver and zinc ions that is being developed for the treatment of infectious diseases and to accelerate wound healing; CNM-ZnAg, a broad-spectrum antiviral and antibacterial agent to treat infection disease, such as COVID-19 and to provide immune support for symptom resolution; and CNM-PtAu7, a gold-platinum CSN therapeutic for oncology applications. It also markets and distributes dietary supplements comprising rMetx, an aqueous zinc-silver ion dietary supplement; and KHC46, an aqueous gold dietary supplement of very low-concentration Au nanoparticles. The company is headquartered in Salt Lake City, Utah.Show more
  • Revenue$200K-41.5%
  • EBITDA-$22M+31.4%
  • Net Income-$26M+33.6%
  • EPS (Diluted)-2.65+53.3%
  • Gross Margin78.5%-1.3%
  • EBITDA Margin-10794%-17.4%
  • Operating Margin-11541.5%-19.3%
  • Net Margin-13086.5%-13.6%
  • Interest Coverage-8.61+1.0%
Technical→

CLNN Key Insights

Clene Inc. (CLNN) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Negative free cash flow
  • ✗Shares diluted 41.8% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

CLNN Price & Volume

Clene Inc. (CLNN) stock price & volume — 10-year historical chart

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CLNN Growth Metrics

Clene Inc. (CLNN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-0.59%
3 Years-24.94%
TTM-41.52%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM33.57%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM55.62%

Return on Capital

10 Years-99.52%
5 Years-135.7%
3 Years-160.02%
Last Year-189.2%

CLNN Peer Comparison

Clene Inc. (CLNN) competitors in Neuroscience and Psychiatry Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.68B21.489.3811.87%36.49%41.9%0.04
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor7.61B337.95-25.07-100%-58.74%0.00
SAVA logoSAVACassava Sciences, Inc.Direct Competitor94.44M1.96-3.76-95.77%
ACIU logoACIUAC Immune S.A.Direct Competitor302.27M2.97-3.31-86.92%-19.69%-101.6%0.10
NRXP logoNRXPNRx Pharmaceuticals, Inc.Direct Competitor84.43M3.05-2.28-157.28%
BIIB logoBIIBBiogen Inc.Product Competitor28.15B190.6821.591.39%13.92%7.55%0.38
IONS logoIONSIonis Pharmaceuticals, Inc.Product Competitor12.7B76.85-32.2933.87%-30.87%-58.57%5.35
ARVN logoARVNArvinas, Inc.Product Competitor656.24M10.26-8.02-0.3%-30.77%-14.25%0.02

Compare CLNN vs Peers

Clene Inc. (CLNN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ACAD

Most directly comparable listed peer for CLNN.

Scale Benchmark

vs LLY

Larger-name benchmark to compare CLNN against a more recognizable public peer.

Peer Set

Compare Top 5

vs ACAD, PRAX, SAVA, ACIU

CLNN Income Statement

Clene Inc. (CLNN) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue00206K723K473K654K342K200K
Revenue Growth %---250.97%-34.58%38.27%-47.71%-41.52%
Cost of Goods Sold0900K65K289K26K121K70K43K
COGS % of Revenue--31.55%39.97%5.5%18.5%20.47%21.5%
Gross Profit
0▲ 0%
-900K▲ 0%
141K▲ 115.7%
434K▲ 207.8%
447K▲ 3.0%
533K▲ 19.2%
272K▼ 49.0%
157K▼ 42.3%
Gross Margin %--68.45%60.03%94.5%81.5%79.53%78.5%
Gross Profit Growth %--115.67%207.8%3%19.24%-48.97%-42.28%
Operating Expenses323.94K15.43M20.36M50.41M48.86M41.07M33.37M23.24M
OpEx % of Revenue--9881.07%6972.61%10328.96%6280.28%9755.85%11620%
Selling, General & Admin323.94K6.67M3.26M18.81M16.16M14.42M13.31M9.23M
SG&A % of Revenue--1583.5%2602.07%3417.12%2204.59%3890.94%4614.5%
Research & Development6.64M8.76M15.2M28.42M31.92M26.66M20.06M14.01M
R&D % of Revenue--7380.58%3930.29%6748.41%4075.69%5864.91%7005.5%
Other Operating Expenses001.89M3.18M773K000
Operating Income
-323.94K▲ 0%
-16.33M▼ 4941.7%
-20.21M▼ 23.8%
-49.98M▼ 147.2%
-48.41M▲ 3.1%
-40.54M▲ 16.3%
-33.09M▲ 18.4%
-23.08M▲ 30.2%
Operating Margin %---9812.62%-6912.59%-10234.46%-6198.78%-9676.32%-11541.5%
Operating Income Growth %--4941.67%-23.77%-147.24%3.14%16.26%18.37%30.25%
EBITDA348.06K-15.43M-19.25M-49.02M-47.39M-38.84M-31.45M-21.59M
EBITDA Margin %---9345.15%-6780.5%-10019.03%-5938.07%-9195.32%-10794%
EBITDA Growth %--4533.72%-24.75%-154.65%3.33%18.05%19.02%31.35%
D&A (Non-Cash Add-back)672K900K963K955K1.02M1.71M1.65M1.5M
EBIT19.43K-16.07M-17.92M-9.3M-26.62M-44.95M-35.34M-23.08M
Net Interest Income343.37K-88K-950K-870K-3.3M-3.17M-3.2M-2.46M
Interest Income343.37K00001.39M865K223K
Interest Expense088K950K870K3.3M4.56M4.06M2.68M
Other Income/Expense343.37K177K1.34M39.81M18.49M-8.96M-6.31M-3.09M
Pretax Income
19.43K▲ 0%
-16.16M▼ 83248.9%
-18.87M▼ 16.8%
-10.17M▲ 46.1%
-29.92M▼ 194.2%
-49.5M▼ 65.5%
-39.4M▲ 20.4%
-26.17M▲ 33.6%
Pretax Margin %---9160.68%-1406.36%-6325.16%-7569.42%-11520.47%-13086.5%
Income Tax00406K-428K0000
Effective Tax Rate %0%0%-2.15%4.21%0%0%0%0%
Net Income
-277.31K▲ 0%
-16.16M▼ 5725.6%
-19.28M▼ 19.3%
-9.74M▲ 49.5%
-29.92M▼ 207.2%
-49.5M▼ 65.5%
-39.4M▲ 20.4%
-26.17M▲ 33.6%
Net Margin %---9357.77%-1347.16%-6325.16%-7569.42%-11520.47%-13086.5%
Net Income Growth %--5725.59%-19.33%49.47%-207.17%-65.47%20.41%33.57%
Net Income (Continuing)19.43K-16.16M-19.28M-9.74M-29.92M-49.5M-39.4M-26.17M
Discontinued Operations00000000
Minority Interest00000000
EPS (Diluted)
-0.09▲ 0%
-4.69▼ 5175.6%
-5.51▼ 17.5%
-3.16▲ 42.6%
-4.69▼ 48.4%
-9.43▼ 101.1%
-5.67▲ 39.9%
-2.65▲ 53.3%
EPS Growth %--5175.59%-17.48%42.65%-48.42%-101.07%39.87%53.26%
EPS (Basic)-0.09-4.69-5.51-3.16-4.69-9.43-5.67-2.65
Diluted Shares Outstanding3.12M3.47M3.5M3.08M3.26M5.25M6.95M9.86M
Basic Shares Outstanding3.12M3.47M3.5M3.08M3.26M5.25M6.95M9.86M
Dividend Payout Ratio--------

CLNN Balance Sheet

Clene Inc. (CLNN) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets790.48K9.48M62.99M54.58M29.2M38.85M16.16M8.98M
Cash & Short-Term Investments743.78K8.79M59.27M50.29M23.32M35M12.15M5.19M
Cash Only743.78K8.79M59.27M50.29M18.33M28.82M12.15M5.19M
Short-Term Investments00004.98M6.18M00
Accounts Receivable002.17M1.61M2.97M1.34M391K0
Days Sales Outstanding--3.84K814.312.29K746.74417.3-
Inventory028K191K41K43K37K68K37K
Days Inventory Outstanding-11.361.07K51.78603.65111.61354.57314.07
Other Current Assets0248K112K2.45M2.87M2.48M137K3.75M
Total Non-Current Assets46.37M5.4M5.25M8.48M15.3M13.49M11.18M9.15M
Property, Plant & Equipment4.47M5.4M5.25M8.42M15.24M13.43M11.12M9.1M
Fixed Asset Turnover--0.04x0.09x0.03x0.05x0.03x0.02x
Goodwill00000000
Intangible Assets00000000
Long-Term Investments46.37M0058K58K058K58K
Other Non-Current Assets-4.47M000058K00
Total Assets
47.16M▲ 0%
14.88M▼ 68.5%
68.24M▲ 358.7%
63.06M▼ 7.6%
44.49M▼ 29.4%
52.34M▲ 17.6%
27.34M▼ 47.8%
18.13M▼ 33.7%
Asset Turnover--0.00x0.01x0.01x0.01x0.01x0.01x
Asset Growth %--68.45%358.71%-7.59%-29.45%17.64%-47.77%-33.68%
Total Current Liabilities222.24K4.31M11.67M6.03M13.86M25.33M10.29M10.78M
Accounts Payable0889K1.12M1.92M3.01M1.5M1.24M892K
Days Payables Outstanding-360.546.31K2.43K42.31K4.54K6.47K7.57K
Short-Term Debt3M416K006.42M19.5M359K4.88M
Deferred Revenue (Current)-4.1M80K413K0002.67M0
Other Current Liabilities68K2.11M7.15M520K02.12M05M
Current Ratio3.56x2.20x5.40x9.06x2.11x1.53x1.57x0.83x
Quick Ratio3.56x2.19x5.38x9.05x2.10x1.53x1.56x0.83x
Cash Conversion Cycle---1.4K-1.56K-39.42K-3.68K-5.69K-
Total Non-Current Liabilities41.94M5.68M56.23M44.44M27.4M13.62M25.9M24.95M
Long-Term Debt0640K1.95M19.08M19.25M7.15M15.43M13.54M
Capital Lease Obligations224K1.82M1.99M4.47M5.59M4.9M4.13M3.25M
Deferred Tax Liabilities-224K0260K00000
Other Non-Current Liabilities39.87M1.37M52.03M20.89M2.56M1.57M6.34M8.16M
Total Liabilities42.16M9.99M67.9M50.47M41.26M38.95M36.19M35.72M
Total Debt3.22M2.88M4.32M24.04M31.82M32.16M20.84M21.67M
Net Debt2.48M-5.91M-54.95M-26.25M13.49M3.34M8.69M16.48M
Debt / Equity0.64x0.59x12.68x1.91x9.83x2.40x--
Debt / EBITDA9.26x-------
Net Debt / EBITDA7.13x-------
Interest Coverage--182.58x-18.86x-10.69x-8.08x-9.86x-8.69x-8.61x
Total Equity
5M▲ 0%
4.89M▼ 2.3%
341K▼ 93.0%
12.6M▲ 3594.1%
3.24M▼ 74.3%
13.39M▲ 313.7%
-8.86M▼ 166.1%
-17.59M▼ 98.6%
Equity Growth %--2.26%-93.02%3594.13%-74.3%313.65%-166.15%-98.62%
Book Value per Share1.601.410.104.090.992.55-1.27-1.78
Total Shareholders' Equity5M4.89M341K12.6M3.24M13.39M-8.86M-17.59M
Common Stock1992K6K6K7K13K1K1K
Retained Earnings17.04K-69.57M-153.56M-163.3M-193.22M-242.72M-282.12M-308.3M
Treasury Stock-1.33M0000000
Accumulated OCI27.18K41K325K233K203K199K71K172K
Minority Interest00000000

CLNN Cash Flow Statement

Clene Inc. (CLNN) cash flow — operating, investing & free cash flow history

Line itemDec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-205.37K-13.2M-18.93M-34.62M-39.01M-30.17M-21.33M-18.55M
Operating CF Margin %---9188.84%-4788.94%-8247.57%-4613.3%-6235.67%-9273%
Operating CF Growth %--6325.9%-43.43%-82.92%-12.67%22.66%29.32%13.04%
Net Income-277.31K-16.16M-19.28M-9.74M-29.92M-49.5M-39.4M-26.17M
Depreciation & Amortization672K848K963K955K1.02M1.71M1.65M1.5M
Stock-Based Compensation269K399K761K12.38M8.51M9.12M7.95M6.38M
Deferred Taxes00000000
Other Non-Cash Items-46.6K554K1.97M-39.23M-17.09M8.7M5.26M3.1M
Working Capital Changes118.54K1.16M-3.35M1M-1.54M-191K3.21M-3.35M
Change in Receivables00-21K-28K-140K46K79K64K
Change in Inventory0-28K-163K150K-2K6K-31K31K
Change in Payables0-76K-312K1.27M285K-1.51M-264K-348K
Cash from Investing-46M-294K-387K-1.33M-10.16M-1.5M6.32M-39K
Capital Expenditures-752K-294K-387K-1.33M-5.18M-330K-15K-39K
CapEx % of Revenue--187.86%184.23%1094.93%50.46%4.39%19.5%
Acquisitions00000000
Investments--------
Other Investing00000000
Cash from Financing46.95M5.5M69.53M27.11M17.25M42.16M-1.53M11.52M
Debt Issued (Net)3.88M-3.18M5.93M19.84M5.56M269K-10.9M-384K
Equity Issued (Net)08.07M35.05M9.25M11.46M42.09M9.24M10.4M
Dividends Paid00000000
Share Repurchases00000000
Other Financing15.9M610K28.55M-1.98M229K-200K124K1.5M
Net Change in Cash
787.78K▲ 0%
-7.99M▼ 1114.1%
50.49M▲ 732.0%
-8.93M▼ 117.7%
-31.96M▼ 257.9%
10.49M▲ 132.8%
-16.67M▼ 258.9%
-6.97M▲ 58.2%
Free Cash Flow
-957.37K▲ 0%
-13.49M▼ 1309.2%
-19.32M▼ 43.2%
-35.96M▼ 86.1%
-44.19M▼ 22.9%
-30.5M▲ 31.0%
-21.34M▲ 30.0%
-18.59M▲ 12.9%
FCF Margin %---9376.7%-4973.17%-9342.49%-4663.76%-6240.06%-9292.5%
FCF Growth %--1309.17%-43.18%-86.15%-22.9%30.98%30.03%12.91%
FCF per Share-0.31-3.89-5.52-11.68-13.55-5.81-3.07-1.89
FCF Conversion (FCF/Net Income)0.74x0.82x0.98x3.55x1.30x0.61x0.54x0.71x
Interest Paid048K39K1.09M2.32M3.06M2.61M0
Taxes Paid00000000

CLNN Key Ratios

Clene Inc. (CLNN) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric20182019202020212022202320242025
Return on Equity (ROE)-5.55%-326.79%-737.45%-150.56%-377.9%-595.47%-1738.36%-
Return on Invested Capital (ROIC)--379.33%---2357.58%-181.74%-299.74%-
Gross Margin--68.45%60.03%94.5%81.5%79.53%78.5%
Net Margin---9357.77%-1347.16%-6325.16%-7569.42%-11520.47%-13086.5%
Debt / Equity0.64x0.59x12.68x1.91x9.83x2.40x--
Interest Coverage--182.58x-18.86x-10.69x-8.08x-9.86x-8.69x-8.61x
FCF Conversion0.74x0.82x0.98x3.55x1.30x0.61x0.54x0.71x
Revenue Growth---250.97%-34.58%38.27%-47.71%-41.52%

CLNN SEC Filings & Documents

Clene Inc. (CLNN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 5, 2026·SEC

Material company update

May 4, 2026·SEC

Material company update

Mar 17, 2026·SEC

10-K Annual Reports

2
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 24, 2025·SEC

10-Q Quarterly Reports

4
FY 2025

Nov 13, 2025·SEC

FY 2025

Aug 14, 2025·SEC

FY 2025

May 7, 2025·SEC

CLNN Frequently Asked Questions

Clene Inc. (CLNN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Clene Inc. (CLNN) reported $0.2M in revenue for fiscal year 2025.

Clene Inc. (CLNN) saw revenue decline by 41.5% over the past year.

Clene Inc. (CLNN) reported a net loss of $26.2M for fiscal year 2025.

Dividend & Returns

Clene Inc. (CLNN) had negative free cash flow of $18.6M in fiscal year 2025, likely due to heavy capital investments.

Explore More CLNN

Clene Inc. (CLNN) financial analysis — history, returns, DCA and operating performance tools

Total Return Calculator

Historical returns with dividends reinvested

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DCA Calculator

Dollar cost averaging vs lump sum

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Dividend History

Yield, growth, payout safety & DRIP

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Earnings History

EPS trends, net income & profitability

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Price History

Long-term charts & historical price data

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Revenue History

Sales growth patterns & revenue breakdown

→

Financial Ratios

30 years of market, efficiency and balance-sheet ratios

→

Valuation

DCF intrinsic value, peer multiples & estimates

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