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ALEC logoAlector, Inc.(ALEC)Earnings, Financials & Key Ratios

ALEC•NASDAQ
Price updated Jun 19, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryNeuroscience and Psychiatry Therapies
AboutAlector, Inc., a clinical stage biopharmaceutical company, develops therapies for the treatment of neurodegeneration diseases. Its products include AL001, a humanized recombinant monoclonal antibody, which is in Phase III clinical trial for the treatment of frontotemporal dementia, Alzheimer's, Parkinson's, and amyotrophic lateral sclerosis diseases; and AL101 that is in Phase I clinical trial for the treatment of neurodegenerative diseases, including Alzheimer's and Parkinson's diseases. The company also offers AL002, a product candidate that is in Phase II clinical trial for the treatment of Alzheimer's disease; and AL003, which is in Phase I clinical trial for the treatment of Alzheimer's disease. In addition, its products in development stage include AL044 that targets MS4A4A, a risk gene for Alzheimer's disease. Alector, Inc. has a collaboration agreement with Adimab, LLC for the research and development of antibodies; and a strategic collaboration agreement with GlaxoSmithKline plc for the development and commercialization of monoclonal antibodies, such as AL001 and AL101 to treat neurodegenerative diseases. The company was founded in 2013 and is headquartered in South San Francisco, California.Show more
  • Revenue$21M-79.1%
  • EBITDA-$136M
  • Net Income-$143M-20.1%
  • EPS (Diluted)-1.39-13.0%
  • Gross Margin54.09%-45.9%
  • EBITDA Margin-646.93%-377.8%
  • Operating Margin-692.83%-380.5%
  • Net Margin-679.16%-473.7%
  • ROE-181.56%-99.0%

ALEC Key Insights

Alector, Inc. (ALEC) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓High quality earnings: Operating CF exceeds net income

✗Weaknesses

  • ✗Weak Piotroski F-Score: 1/9
  • ✗Negative free cash flow
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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ALEC Price & Volume

Alector, Inc. (ALEC) stock price & volume — 10-year historical chart

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ALEC Growth Metrics

Alector, Inc. (ALEC) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-0.05%
3 Years-46%
TTM-79.15%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-1.58%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM6.38%

Return on Capital

10 Years-30.34%
5 Years-28.38%
3 Years-38.32%
Last Year-51.43%

ALEC Recent Earnings

Alector, Inc. (ALEC) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 12/12 qtrs (100%)●Beat Revenue 8/12 qtrs (67%)
Q2 2026Latest
May 7, 2026
Metric
Actual
Est
EPS
$0.21+40.0%
$0.35
Rev
$1M-89.2%
$10M
Q1 2026
Feb 25, 2026
Metric
Actual
Est
EPS
$0.34+12.8%
$0.39
Rev
$6M+218.6%
$2M
Q4 2025
Nov 6, 2025
Metric
Actual
Est
EPS
$0.34+19.0%
$0.42
Rev
$3M+82.8%
$2M
Q3 2025
Aug 7, 2025
Metric
Actual
Est
EPS
$0.30+33.3%
$0.45
Rev
$8M+180.7%
$3M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.21vs $0.35+40.0%
$1Mvs $10M-89.2%
Q1 2026Feb 25, 2026
$0.34vs $0.39+12.8%
$6Mvs $2M+218.6%
Q4 2025Nov 6, 2025
$0.34vs $0.42+19.0%
$3Mvs $2M+82.8%
Q3 2025Aug 7, 2025
$0.30vs $0.45+33.3%
$8Mvs $3M+180.7%
Based on last 12 quarters of dataView full earnings history →

ALEC Peer Comparison

Alector, Inc. (ALEC) competitors in Neuroscience and Psychiatry Therapies — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
PRTA logoPRTAProthena Corporation plcDirect Competitor467.51M8.93-1.97-92.84%-260.92%-49.88%0.05
ACAD logoACADACADIA Pharmaceuticals Inc.Direct Competitor3.7B21.629.4411.87%34.3%35.65%0.04
SAVA logoSAVACassava Sciences, Inc.Direct Competitor63.77M1.32-2.54-95.77%
AVXL logoAVXLAnavex Life Sciences Corp.Direct Competitor252.99M2.73-5.06-38.76%
INMB logoINMBINmune Bio, Inc.Direct Competitor38.55M1.45-0.78257.14%-170.86%0.04
BIIB logoBIIBBiogen Inc.Product Competitor29.02B196.5822.261.39%13.92%7.55%0.38
IONS logoIONSIonis Pharmaceuticals, Inc.Product Competitor12.25B74.12-31.1433.87%-30.87%-58.57%5.35
ARVN logoARVNArvinas, Inc.Product Competitor494.88M7.67-5.99-0.3%-247.54%-44.39%0.02

Compare ALEC vs Peers

Alector, Inc. (ALEC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs PRTA

Most directly comparable listed peer for ALEC.

Scale Benchmark

vs LLY

Larger-name benchmark to compare ALEC against a more recognizable public peer.

Peer Set

Compare Top 5

vs PRTA, ACAD, SAVA, AVXL

ALEC Income Statement

Alector, Inc. (ALEC) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
3.73M27.68M21.22M21.1M207.09M133.62M97.06M100.56M21.05M18.42M
Revenue Growth %
797.84%641.02%-23.33%-0.57%881.54%-35.48%-27.36%3.6%-79.07%-79.15%
Cost of Goods Sold
29.91M73.03M100.53M156.87M189.41M08.85M09.66M2.08M
COGS % of Revenue
800.83%263.87%473.76%743.53%91.46%-9.12%-45.91%-
Gross Profit
-26.18M▲ 0%
-45.35M▼ 73.3%
-79.31M▼ 74.9%
-135.77M▼ 71.2%
17.68M▲ 113.0%
133.62M▲ 655.8%
88.21M▼ 34.0%
100.56M▲ 14.0%
11.38M▼ 88.7%
16.33M▲ 0%
Gross Margin %
-700.83%-163.87%-373.76%-643.53%8.54%100%90.88%100%54.09%88.68%
Gross Profit Growth %
-97.44%-73.27%-74.87%-71.19%113.02%655.84%-33.98%13.99%-88.68%-
Operating Expenses
36.41M84.97M35.09M59.4M55.04M271.45M239.95M245.56M157.19M152.86M
OpEx % of Revenue
974.94%306.99%165.39%281.56%26.58%203.16%247.22%244.19%746.93%-
Selling, General & Admin
6.5M11.93M33.94M59.4M55.04M61.03M56.69M59.62M53.99M47.37M
SG&A % of Revenue
174.11%43.12%159.94%281.56%26.58%45.68%58.4%59.28%256.53%-
Research & Development
29.91M73.03M100.53M156.87M189.41M210.42M192.12M185.94M123.06M108.58M
R&D % of Revenue
800.83%263.87%473.76%743.53%91.46%157.48%197.93%184.91%584.77%-
Other Operating Expenses
199K5.04M-99.37M-156.87M-189.41M0-8.85M0-19.86M-2M
Operating Income
-32.68M▲ 0%
-57.29M▼ 75.3%
-114.4M▼ 99.7%
-195.17M▼ 70.6%
-37.36M▲ 80.9%
-137.83M▼ 268.9%
-151.74M▼ 10.1%
-145M▲ 4.4%
-145.81M▼ 0.6%
-136.53M▲ 0%
Operating Margin %
-874.94%-206.99%-539.16%-925.08%-18.04%-103.16%-156.33%-144.19%-692.83%-741.33%
Operating Income Growth %
-115.96%-75.31%-99.7%-70.6%80.86%-268.93%-10.09%4.44%-0.56%-
EBITDA
-32M-56.27M-110.63M-187.91M-29.05M-129.36M-142.89M-136.16M-136.15M-127.73M
EBITDA Margin %
-856.73%-203.31%-521.37%-890.65%-14.03%-96.82%-147.22%-135.4%-646.93%-693.54%
EBITDA Growth %
-114.31%-75.85%-96.61%-69.86%84.54%-345.38%-10.46%4.71%0.01%7.16%
D&A (Non-Cash Add-back)
680K1.02M3.77M7.26M8.31M8.47M8.85M8.84M9.66M8.8M
EBIT
-32.68M-57.29M-113.25M-195.17M-37.36M-137.83M-151.74M-145M-142.76M-133.59M
Net Interest Income
0000000000
Interest Income
0000000000
Interest Expense
0000000000
Other Income/Expense
199K5.04M9.02M4.95M1.03M7.78M26.56M26.08M3.05M11.31M
Pretax Income
-32.48M▲ 0%
-52.25M▼ 60.9%
-105.39M▼ 101.7%
-190.23M▼ 80.5%
-36.33M▲ 80.9%
-130.06M▼ 258.0%
-125.18M▲ 3.7%
-118.92M▲ 5.0%
-142.76M▼ 20.0%
-125.22M▲ 0%
Pretax Margin %
-869.61%-188.78%-496.65%-901.64%-17.54%-97.33%-128.97%-118.26%-678.36%-679.92%
Income Tax
000003.25M5.21M128K168K168K
Effective Tax Rate %
0%0%0%0%0%-2.5%-4.16%-0.11%-0.12%-0.13%
Net Income
-32.48M▲ 0%
-52.25M▼ 60.9%
-105.39M▼ 101.7%
-190.23M▼ 80.5%
-36.33M▲ 80.9%
-133.31M▼ 267.0%
-130.39M▲ 2.2%
-119.05M▲ 8.7%
-142.93M▼ 20.1%
-125.39M▲ 0%
Net Margin %
-869.61%-188.78%-496.65%-901.64%-17.54%-99.77%-134.34%-118.39%-679.16%-680.83%
Net Income Growth %
-114.96%-60.86%-101.7%-80.51%80.9%-266.95%2.19%8.7%-20.06%-1.58%
Net Income (Continuing)
-32.48M-52.25M-105.39M-190.23M-36.33M-133.31M-130.39M-119.05M-142.93M-125.39M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-0.63▲ 0%
-0.76▼ 20.6%
-1.62▼ 113.2%
-2.45▼ 51.2%
-0.45▲ 81.6%
-1.62▼ 260.0%
-1.56▲ 3.7%
-1.23▲ 21.2%
-1.39▼ 13.0%
-1.13▲ 0%
EPS Growth %
64.61%-20.63%-113.16%-51.23%81.63%-260%3.7%21.15%-13.01%6.38%
EPS (Basic)
-0.63-0.76-1.62-2.45-0.45-1.62-1.56-1.23-1.39-
Diluted Shares Outstanding
51.22M68.37M61.73M77.76M80.42M82.47M83.73M96.59M103M110.59M
Basic Shares Outstanding
51.22M68.37M61.73M77.76M80.42M82.47M83.73M96.59M103M110.59M
Dividend Payout Ratio
----------

ALEC Balance Sheet

Alector, Inc. (ALEC) balance sheet — assets, liabilities & shareholders' equity

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
232.97M293.18M357.44M421.51M749.71M726.43M565.81M424.82M266.45M215.08M
Cash & Short-Term Investments
32.45M290.41M353.07M413.31M735.25M712.85M548.86M413.4M256.02M206.51M
Cash Only
32.45M65.47M89.64M49.97M329.15M154.32M74.56M33.02M65.8M76.96M
Short-Term Investments
0224.94M263.43M363.34M406.1M558.53M474.31M380.38M190.22M129.55M
Accounts Receivable
200.24M0007.39M2.59M0000
Days Sales Outstanding
19.57K---13.037.07----
Inventory
0000000000
Days Inventory Outstanding
----------
Other Current Assets
02.77M000016.95M11.42M10.43M8.57M
Total Non-Current Assets
3.09M15.18M64.48M66.74M64.94M61.21M56.02M43.49M26.79M24.83M
Property, Plant & Equipment
2.83M10.94M62.33M62.65M57.9M53.33M47.06M37.1M24.55M22.62M
Fixed Asset Turnover
1.32x2.53x0.34x0.34x3.58x2.51x2.06x2.71x0.86x0.69x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
01.47M00000001.85M
Other Non-Current Assets
252K2.77M2.15M4.09M7.05M7.88M8.96M6.39M2.23M2.21M
Total Assets
236.06M▲ 0%
308.36M▲ 30.6%
421.91M▲ 36.8%
488.25M▲ 15.7%
814.66M▲ 66.9%
787.65M▼ 3.3%
621.83M▼ 21.1%
468.3M▼ 24.7%
293.24M▼ 37.4%
239.92M▲ 0%
Asset Turnover
0.02x0.09x0.05x0.04x0.25x0.17x0.16x0.21x0.07x0.06x
Asset Growth %
336.25%30.63%36.83%15.72%66.85%-3.32%-21.05%-24.69%-37.38%-151.2%
Total Current Liabilities
27.4M13.04M61.97M68.09M139.56M93.81M177.95M125.06M69.5M40.97M
Accounts Payable
1.14M126K278K3M4.75M4.19M3.77M2.21M1.69M1.42M
Days Payables Outstanding
13.910.631.016.999.15-155.73-63.89441.71
Short-Term Debt
000000009.42M10.62M
Deferred Revenue (Current)
18.98M34.91M30.16M23.89M90.8M48.23M82.97M23.66M6.68M26.81M
Other Current Liabilities
5.6M9.56M5.73M7.29M11.66M12.76M54.74M54.55M51.71M22.2M
Current Ratio
8.50x22.48x5.77x6.19x5.37x7.74x3.18x3.40x3.83x5.25x
Quick Ratio
8.50x22.48x5.77x6.19x5.37x7.74x3.18x3.40x3.83x5.25x
Cash Conversion Cycle
----------
Total Non-Current Liabilities
260.69M392.71M165.2M152.63M374.38M479.4M309.72M216.44M193.09M188.57M
Long-Term Debt
00000009.39M26.81M23.93M
Capital Lease Obligations
0041.47M43.74M39.81M35.27M30.46M24.38M040.33M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
77.54M7.57M493K472K158K759K68.42M10.51M166.27M1.77M
Total Liabilities
288.09M405.76M227.17M220.72M513.93M573.21M487.67M341.5M262.59M229.53M
Total Debt
0048.04M51.26M47.6M43.33M38.92M42.52M36.23M34.55M
Net Debt
-32.45M-65.47M-41.6M1.29M-281.55M-111M-35.64M9.5M-29.57M-42.41M
Debt / Equity
--0.25x0.19x0.16x0.20x0.29x0.34x1.18x3.33x
Debt / EBITDA
----------0.27x
Net Debt / EBITDA
---------0.33x
Interest Coverage
----------
Total Equity
-52.03M▲ 0%
-97.4M▼ 87.2%
194.74M▲ 299.9%
267.53M▲ 37.4%
300.72M▲ 12.4%
214.44M▼ 28.7%
134.16M▼ 37.4%
126.8M▼ 5.5%
30.65M▼ 75.8%
10.38M▲ 0%
Equity Growth %
-108.91%-87.19%299.95%37.38%12.41%-28.69%-37.44%-5.48%-75.83%-269.06%
Book Value per Share
-1.02-1.423.153.443.742.601.601.310.300.09
Total Shareholders' Equity
-52.03M-97.4M194.74M267.53M300.72M214.44M134.16M126.8M30.65M10.38M
Common Stock
1K1K7K8K8K8K8K9K11K11K
Retained Earnings
-62.19M-114.44M-219.82M-410.05M-446.38M-579.69M-710.08M-829.13M-972.06M-994.99M
Treasury Stock
0193.44M00000000
Accumulated OCI
-980K-42K142K614K-943K-4.58M184K261K166K-104K
Minority Interest
0000000000

ALEC Cash Flow Statement

Alector, Inc. (ALEC) cash flow — operating, investing & free cash flow history

MetricDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-17.77M127.46M-99.31M-166.73M298.55M-20.33M-184.16M-229.91M-184.03M-173.06M
Operating CF Margin %
-475.8%460.54%-468.01%-790.28%144.17%-15.21%-189.74%-228.63%-874.46%-
Operating CF Growth %
-36.77%817.26%-177.91%-67.9%279.06%-106.81%-805.91%-24.84%19.95%100.1%
Net Income
-32.48M-52.25M-105.39M-190.23M-36.33M-133.31M-130.39M-119.05M-142.93M-125.39M
Depreciation & Amortization
680K1.02M5.57M7.26M8.31M8.47M8.85M8.84M-861K8.78M
Stock-Based Compensation
5.35M6.92M16.28M30.52M40.78M46.15M42.8M39.46M26.66M21.21M
Deferred Taxes
0000000000
Other Non-Cash Items
6.78M-2.59M-3.5M929K2.1M-1.16M-15.27M-12.17M7.16M-879K
Working Capital Changes
8.68M174.36M-12.27M-15.22M283.68M59.53M-90.15M-146.99M-74.06M-76.79M
Change in Receivables
-20K238K00-7.39M4.8M2.59M000
Change in Inventory
6.58M2.45M00000000
Change in Payables
-41K-809K152K2.41M1.92M-572K-377K-1.44M-524K-903K
Cash from Investing
-801K-224.12M-48.87M-105.05M-49.66M-159.01M101.92M107.13M196.6M191.81M
Capital Expenditures
-801K-1.88M-15.27M-5.03M-3.25M-4.12M-2.38M-1.25M-41K-139K
CapEx % of Revenue
21.45%6.81%71.94%23.85%1.57%3.08%2.45%1.25%0.19%0.75%
Acquisitions
000100.02M000000
Investments
----------
Other Investing
0-222.24M0-100.02M000000
Cash from Financing
-15K131.15M172.35M232.11M30.3M4.51M2.55M81.54M20.21M20.24M
Debt Issued (Net)
00000009.39M00
Equity Issued (Net)
00172.35M224.6M04.51M2.55M71.11M20M20.02M
Dividends Paid
0000000000
Share Repurchases
-15K-1.9M00000000
Other Financing
-15K131.15M07.51M30.3M001.04M217K217K
Net Change in Cash
-18.59M▲ 0%
34.49M▲ 285.6%
24.17M▼ 29.9%
-39.67M▼ 264.1%
279.18M▲ 803.7%
-174.83M▼ 162.6%
-79.69M▲ 54.4%
-41.23M▲ 48.3%
32.78M▲ 179.5%
38.99M▲ 0%
Free Cash Flow
-18.57M▲ 0%
125.58M▲ 776.2%
-114.57M▼ 191.2%
-171.77M▼ 49.9%
295.3M▲ 271.9%
-24.45M▼ 108.3%
-186.54M▼ 663.1%
-231.16M▼ 23.9%
-184.07M▲ 20.4%
-173.2M▲ 0%
FCF Margin %
-497.24%453.73%-539.95%-814.13%142.6%-18.3%-192.19%-229.88%-874.66%-940.44%
FCF Growth %
-21.84%776.18%-191.24%-49.92%271.92%-108.28%-663.08%-23.92%20.37%24.72%
FCF per Share
-0.361.84-1.86-2.213.67-0.30-2.23-2.39-1.79-1.57
FCF Conversion (FCF/Net Income)
0.55x-2.44x0.94x0.88x-8.22x0.15x1.41x1.93x1.29x1.38x
Interest Paid
0000000004K
Taxes Paid
0000000000

ALEC Key Ratios

Alector, Inc. (ALEC) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201720182019202020212022202320242025TTM
Return on Equity (ROE)
---216.52%-82.3%-12.79%-51.75%-74.81%-91.24%-181.56%-295.17%
Return on Invested Capital (ROIC)
----69.38%-19.46%-168.61%-112.7%-92.62%-159.2%-758.24%
Gross Margin
-700.83%-163.87%-373.76%-643.53%8.54%100%90.88%100%54.09%88.68%
Net Margin
-869.61%-188.78%-496.65%-901.64%-17.54%-99.77%-134.34%-118.39%-679.16%-680.83%
Debt / Equity
--0.25x0.19x0.16x0.20x0.29x0.34x1.18x3.33x
FCF Conversion
0.55x-2.44x0.94x0.88x-8.22x0.15x1.41x1.93x1.29x1.38x
Revenue Growth
797.84%641.02%-23.33%-0.57%881.54%-35.48%-27.36%3.6%-79.07%-79.15%
Related:ALEC Dividend History·ALEC Revenue History·ALEC Price History·ALEC P/E History·ALEC Financial Ratios·ALEC Institutional Holders

ALEC SEC Filings & Documents

Alector, Inc. (ALEC) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

May 7, 2026·SEC

Material company update

Feb 25, 2026·SEC

10-K Annual Reports

4
FY 2026

Feb 25, 2026·SEC

FY 2025

Feb 26, 2025·SEC

FY 2024

Feb 27, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

ALEC Frequently Asked Questions

Alector, Inc. (ALEC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Alector, Inc. (ALEC) reported $18.4M in revenue for fiscal year 2025. This represents a 4327% increase from $0.4M in 2016.

Alector, Inc. (ALEC) saw revenue decline by 79.1% over the past year.

Alector, Inc. (ALEC) reported a net loss of $125.4M for fiscal year 2025.

Dividend & Returns

Alector, Inc. (ALEC) has a return on equity (ROE) of -181.6%. Negative ROE indicates the company is unprofitable.

Alector, Inc. (ALEC) had negative free cash flow of $173.2M in fiscal year 2025, likely due to heavy capital investments.

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