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Alto Neuroscience, Inc. (ANRO) 10-Year Financial Performance & Capital Metrics

ANRO • • Industrial / General
HealthcareBiotechnologyNeurology & CNS DisordersPsychiatric & CNS Disorders
AboutAlto Neuroscience, Inc. operates as a clinical-stage biopharmaceutical company that engages in the psychiatry drug development business. The company develops ALTO-100 for the treatment of patients with major depressive disorder (MDD) and post-traumatic stress disorder; ALTO-300, a small molecule melatonergic agonist and serotonergic antagonist with antidepressant properties to treat patients with MDD; and ALTO-101, a novel small molecule phosphodiesterase 4 inhibitor for the treatment of cognitive impairment associated with schizophrenia. It also develops ALTO-203, a novel small-molecule histamine H3 receptor inverse agonist to treat patients with MDD and higher levels of anhedonia, and ALTO-202, an investigational orally bioavailable antagonist of the GluN2B subunit of the NMDA receptor for the treatment of MDD. In addition, the company develops novel pharmacodynamically synergistic combinations and an AI-enabled biomarker platform that combine sources of information on patients brain activity and behavior to identify patients to respond to novel product candidates. Alto Neuroscience, Inc. was incorporated in 2019 and is based in Los Altos, California.Show more
  • Revenue $0
  • EBITDA -$74M -98.8%
  • Net Income -$61M -69.2%
  • EPS (Diluted) -2.50 -85.2%
  • Gross Margin -
  • EBITDA Margin -
  • Operating Margin -
  • Net Margin -
  • ROE -153.99%
  • ROIC -
  • Debt/Equity 0.11
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 98 (top 2%)
  • ✓Share count reduced 8.5% through buybacks

✗Weaknesses

  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-8.37%

EPS CAGR

10Y-
5Y-
3Y-
TTM-7.51%

ROCE

10Y Avg-60.13%
5Y Avg-60.13%
3Y Avg-65.28%
Latest-55.21%

Peer Comparison

Psychiatric & CNS Disorders
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TTM Growth
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Technical
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HRMYHarmony Biosciences Holdings, Inc.2.1B36.4114.5122.8%22.48%22.23%10.43%0.28
ALKSAlkermes plc5.15B31.2214.39-6.36%22.27%19.55%7.87%0.05
PRTCPureTech Health plc463.31M19.179.5944.98%-495.91%-8.53%0.05
LBRXLB Pharmaceuticals Inc Common Stock540.89M21.38-1.20
NMRANeumora Therapeutics, Inc. Common Stock361.97M2.13-1.39-178.79%0.01

Profit & Loss

Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+210K000
Revenue Growth %--1%--
Cost of Goods Sold+145K342K0502K
COGS % of Revenue0.69%---
Gross Profit+65K-342K0-502K
Gross Margin %0.31%---
Gross Profit Growth %--6.26%1%-
Operating Expenses+12.12M28.85M37.81M68.11M
OpEx % of Revenue57.72%---
Selling, General & Admin3.75M5.16M7.52M21.61M
SG&A % of Revenue17.86%---
Research & Development8.37M23.69M30.29M47M
R&D % of Revenue39.86%---
Other Operating Expenses000-502K
Operating Income+-12.06M-29.19M-37.81M-68.61M
Operating Margin %-57.41%---
Operating Income Growth %--1.42%-0.3%-0.81%
EBITDA+-11.91M-28.85M-37.44M-74.41M
EBITDA Margin %-56.72%---
EBITDA Growth %--1.42%-0.3%-0.99%
D&A (Non-Cash Add-back)145K342K373K-5.8M
EBIT-9.19M-27.71M-34.94M-62.81M
Net Interest Income+2K114K979K10.23M
Interest Income2K114K2.35M8.85M
Interest Expense001.37M-1.38M
Other Income/Expense2.87M1.48M1.5M7.18M
Pretax Income+-9.19M-27.71M-36.3M-61.43M
Pretax Margin %-43.75%---
Income Tax+0000
Effective Tax Rate %1%1%1%1%
Net Income+-9.19M-27.71M-36.3M-61.43M
Net Margin %-43.75%---
Net Income Growth %--2.02%-0.31%-0.69%
Net Income (Continuing)-9.19M-27.71M-36.3M-61.43M
Discontinued Operations0000
Minority Interest0000
EPS (Diluted)+-0.36-1.08-1.35-2.50
EPS Growth %--2%-0.25%-0.85%
EPS (Basic)-0.36-1.08-1.35-2.50
Diluted Shares Outstanding25.57M25.57M26.88M24.6M
Basic Shares Outstanding25.57M25.57M26.88M24.6M
Dividend Payout Ratio----

Balance Sheet

Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+27.68M49.22M85.39M169.34M
Cash & Short-Term Investments25.7M48.34M82.55M168.23M
Cash Only25.7M48.34M82.55M168.23M
Short-Term Investments0000
Accounts Receivable1.74M546K8K0
Days Sales Outstanding3.03K---
Inventory0000
Days Inventory Outstanding----
Other Current Assets002.31M30K
Total Non-Current Assets+1.11M1.63M1.24M8.21M
Property, Plant & Equipment1.06M1.58M1.11M7.7M
Fixed Asset Turnover0.20x---
Goodwill0000
Intangible Assets0000
Long-Term Investments000500K
Other Non-Current Assets50K55K131K4K
Total Assets+28.79M50.85M86.63M177.54M
Asset Turnover0.01x---
Asset Growth %-0.77%0.7%1.05%
Total Current Liabilities+1.81M5.56M5.61M10.01M
Accounts Payable600K1.61M1.07M1.58M
Days Payables Outstanding1.51K1.71K-1.15K
Short-Term Debt0283K00
Deferred Revenue (Current)0000
Other Current Liabilities1.19M3.54M00
Current Ratio15.30x8.85x15.22x16.92x
Quick Ratio15.30x8.85x15.22x16.92x
Cash Conversion Cycle----
Total Non-Current Liabilities+39.46M83.7M152.69M16.07M
Long-Term Debt38.16M81.7M9.86M11.56M
Capital Lease Obligations0123K04.52M
Deferred Tax Liabilities0000
Other Non-Current Liabilities1.3M1.88M142.83M0
Total Liabilities41.27M89.26M158.3M26.08M
Total Debt+38.16M82.11M9.99M16.94M
Net Debt12.46M33.76M-72.56M-151.28M
Debt / Equity---0.11x
Debt / EBITDA----
Net Debt / EBITDA----
Interest Coverage---27.60x-
Total Equity+-12.48M-38.41M-71.67M151.46M
Equity Growth %--2.08%-0.87%3.11%
Book Value per Share-0.49-1.50-2.676.16
Total Shareholders' Equity-12.48M-38.41M-71.67M151.46M
Common Stock1K1K03K
Retained Earnings-12.95M-40.66M-76.97M-138.4M
Treasury Stock0000
Accumulated OCI-22K-46K-79K-101K
Minority Interest0000

Cash Flow

Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-9.26M-20.39M-33.45M-47.42M
Operating CF Margin %-44.1%---
Operating CF Growth %--1.2%-0.64%-0.42%
Net Income-9.19M-27.71M-36.3M-61.43M
Depreciation & Amortization145K342K373K502K
Stock-Based Compensation227K1.76M2.89M7.63M
Deferred Taxes0000
Other Non-Cash Items125K632K291K1.81M
Working Capital Changes-572K4.58M-698K4.06M
Change in Receivables-1.28M1.16M325K0
Change in Inventory0000
Change in Payables458K1.01M-632K516K
Cash from Investing+-680K-732K-470K-2.08M
Capital Expenditures-680K-732K-470K-2.08M
CapEx % of Revenue3.24%---
Acquisitions----
Investments----
Other Investing0000
Cash from Financing+31.69M43.79M68.13M135.69M
Debt Issued (Net)----
Equity Issued (Net)----
Dividends Paid0000
Share Repurchases----
Other Financing-205K-341K-1.87M-3.14M
Net Change in Cash----
Free Cash Flow+-9.94M-21.13M-33.92M-49.5M
FCF Margin %-47.34%---
FCF Growth %--1.12%-0.61%-0.46%
FCF per Share-0.39-0.83-1.26-2.01
FCF Conversion (FCF/Net Income)1.01x0.74x0.92x0.77x
Interest Paid00912K0
Taxes Paid0000

Key Ratios

Metric2021202220232024
Return on Equity (ROE)----153.99%
Gross Margin30.95%---
Net Margin-4374.76%---
Debt / Equity---0.11x
Interest Coverage---27.60x-
FCF Conversion1.01x0.74x0.92x0.77x
Revenue Growth--100%--

Frequently Asked Questions

Growth & Financials

Alto Neuroscience, Inc. (ANRO) grew revenue by 0.0% over the past year. Growth has been modest.

Alto Neuroscience, Inc. (ANRO) reported a net loss of $62.3M for fiscal year 2024.

Dividend & Returns

Alto Neuroscience, Inc. (ANRO) has a return on equity (ROE) of -154.0%. Negative ROE indicates the company is unprofitable.

Alto Neuroscience, Inc. (ANRO) had negative free cash flow of $53.8M in fiscal year 2024, likely due to heavy capital investments.

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