| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| CORTCorcept Therapeutics Incorporated | 3.78B | 35.70 | 43.54 | 12.79% | 13.01% | 15.3% | 3.75% | 0.01 |
| BMRNBioMarin Pharmaceutical Inc. | 11.86B | 61.73 | 34.29 | 10.83% | 5.73% | 6.11% | 0.10 | |
| VRTXVertex Pharmaceuticals Incorporated | 126.19B | 496.83 | 32.43 | 8.9% | 31.35% | 21.22% | 2.53% | 0.20 |
| CPRXCatalyst Pharmaceuticals, Inc. | 2.83B | 23.08 | 13.74 | 19.78% | 36.39% | 22.46% | 7.38% | 0.00 |
| HRMYHarmony Biosciences Holdings, Inc. | 1.65B | 28.54 | 10.53 | 21.51% | 18.27% | 18.24% | 21.12% | 0.02 |
| PTCTPTC Therapeutics, Inc. | 5.45B | 68.19 | 8.76 | 114.51% | 42.25% | |||
| BCRXBioCryst Pharmaceuticals, Inc. | 1.86B | 8.75 | 7.23 | 94.1% | 30.16% | 18.63% | ||
| RAREUltragenyx Pharmaceutical Inc. | 2.26B | 23.39 | -3.72 | 29.01% | -91.95% | -35.88% | 0.15 |
Analyze head-to-head performance against top industry competitors across valuation, growth, and profitability metrics.
| Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 6M | 159.74M | 305.44M | 437.86M | 582.02M | 714.73M | 868.45M |
| Revenue Growth % | - | - | 2564.59% | 91.21% | 43.35% | 32.93% | 22.8% | 21.51% |
| Cost of Goods Sold | 184K | 1.58M | 27.74M | 55.52M | 83.48M | 121.24M | 156.81M | 198.34M |
| COGS % of Revenue | - | 26.31% | 17.36% | 18.18% | 19.07% | 20.83% | 21.94% | 22.84% |
| Gross Profit | -184K | 4.42M | 132M | 249.92M | 354.37M | 460.79M | 557.92M | 670.11M |
| Gross Margin % | - | 73.69% | 82.64% | 81.82% | 80.93% | 79.17% | 78.06% | 77.16% |
| Gross Profit Growth % | - | 2501.09% | 2887.87% | 89.33% | 41.79% | 30.03% | 21.08% | 20.11% |
| Operating Expenses | 41.44M | 150.32M | 115.02M | 162.39M | 234.19M | 268.76M | 367.09M | 461.64M |
| OpEx % of Revenue | - | 2507.46% | 72% | 53.17% | 53.49% | 46.18% | 51.36% | 53.16% |
| Selling, General & Admin | 29.07M | 80.73M | 95.57M | 132.03M | 163.3M | 192.69M | 221.27M | 272.05M |
| SG&A % of Revenue | - | 1346.57% | 59.83% | 43.23% | 37.3% | 33.11% | 30.96% | 31.33% |
| Research & Development | 12.37M | 69.59M | 19.45M | 30.37M | 70.89M | 76.06M | 145.82M | 189.59M |
| R&D % of Revenue | - | 1160.88% | 12.17% | 9.94% | 16.19% | 13.07% | 20.4% | 21.83% |
| Other Operating Expenses | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Operating Income | -41.44M | -145.9M | 16.99M | 87.53M | 120.19M | 192.03M | 190.83M | 208.47M |
| Operating Margin % | - | -2433.76% | 10.63% | 28.66% | 27.45% | 32.99% | 26.7% | 24% |
| Operating Income Growth % | - | -252.09% | 111.64% | 415.29% | 37.31% | 59.78% | -0.63% | 9.25% |
| EBITDA | -41.26M | -142.69M | 27.22M | 106.37M | 143.57M | 216.39M | 214.94M | 232.32M |
| EBITDA Margin % | - | -2380.22% | 17.04% | 34.82% | 32.79% | 37.18% | 30.07% | 26.75% |
| EBITDA Growth % | - | -245.88% | 119.08% | 290.73% | 34.98% | 50.72% | -0.67% | 8.08% |
| D&A (Non-Cash Add-back) | 184K | 3.21M | 10.24M | 18.84M | 23.39M | 24.36M | 24.11M | 23.85M |
| EBIT | -41.44M | -145.9M | -8.72M | 61.62M | 123.48M | 197.15M | 209.3M | 229.71M |
| Net Interest Income | 0 | -6.07M | -28.22M | -23.97M | -15.67M | -9.03M | 1.05M | 7.28M |
| Interest Income | 0 | 0 | 0 | 224K | 3.13M | 14.73M | 18.54M | 21.92M |
| Interest Expense | 0 | 6.07M | 28.22M | 24.19M | 18.8M | 23.76M | 17.5M | 14.65M |
| Other Income/Expense | 1.54M | -6.07M | -53.93M | -50.1M | -15.5M | -18.63M | 978K | 6.59M |
| Pretax Income | -39.9M | -151.98M | -36.94M | 37.43M | 104.69M | 173.4M | 191.8M | 215.06M |
| Pretax Margin % | - | -2535.06% | -23.13% | 12.25% | 23.91% | 29.79% | 26.84% | 24.76% |
| Income Tax | 0 | 0 | 0 | 2.83M | -76.78M | 44.54M | 46.31M | 56.38M |
| Effective Tax Rate % | 100% | 100% | 100% | 92.44% | 173.35% | 74.31% | 75.85% | 73.79% |
| Net Income | -39.9M | -151.98M | -36.94M | 34.6M | 181.47M | 128.85M | 145.49M | 158.69M |
| Net Margin % | - | -2535.06% | -23.13% | 11.33% | 41.44% | 22.14% | 20.36% | 18.27% |
| Net Income Growth % | - | -280.91% | 75.69% | 193.65% | 424.52% | -28.99% | 12.91% | 9.07% |
| Net Income (Continuing) | -39.9M | -151.98M | -36.94M | 34.6M | 181.47M | 128.85M | 145.49M | 158.69M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -1.42 | -2.94 | -1.10 | 0.58 | 2.97 | 2.13 | 2.51 | 2.71 |
| EPS Growth % | - | -107.04% | 62.59% | 152.73% | 412.07% | -28.28% | 17.84% | 7.97% |
| EPS (Basic) | -1.42 | -2.94 | -1.12 | 0.60 | 3.07 | 2.17 | 2.56 | 2.76 |
| Diluted Shares Outstanding | 49.24M | 63.68M | 57.85M | 59.21M | 61.1M | 60.37M | 57.87M | 58.54M |
| Basic Shares Outstanding | 49.24M | 63.68M | 56.89M | 57.53M | 59.17M | 59.47M | 56.88M | 57.49M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - |
| Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 86.68M | 31.5M | 262.89M | 284.44M | 400.29M | 451.07M | 579.25M | 907.01M |
| Cash & Short-Term Investments | 83.52M | 24.46M | 228.63M | 234.31M | 323.12M | 353.46M | 467.19M | 752.5M |
| Cash Only | 83.52M | 24.46M | 228.63M | 234.31M | 243.78M | 311.66M | 453M | 752.5M |
| Short-Term Investments | 0 | 0 | 0 | 0 | 79.33M | 41.8M | 14.19M | 0 |
| Accounts Receivable | 0 | 4.25M | 22.18M | 34.84M | 54.74M | 74.14M | 83.03M | 96.79M |
| Days Sales Outstanding | - | 259.06 | 50.67 | 41.64 | 45.63 | 46.49 | 42.4 | 40.68 |
| Inventory | 0 | 1.09M | 3.82M | 4.43M | 4.3M | 5.36M | 7.2M | 5.36M |
| Days Inventory Outstanding | - | 251.82 | 50.31 | 29.14 | 18.79 | 16.15 | 16.75 | 9.86 |
| Other Current Assets | 2.46M | 261K | 1.3M | 3.22M | 8.79M | 5.54M | 8.12M | 52.37M |
| Total Non-Current Assets | 2.6M | 75.21M | 164.18M | 149M | 273.58M | 360.38M | 419.95M | 364.62M |
| Property, Plant & Equipment | 1.58M | 1.33M | 938K | 4.12M | 573K | 371K | 3.38M | 0 |
| Fixed Asset Turnover | - | 4.51x | 170.30x | 74.17x | 764.14x | 1568.79x | 211.52x | - |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 72.19M | 162.34M | 143.92M | 160.95M | 137.11M | 113.26M | 89.42M |
| Long-Term Investments | 500K | 0 | 0 | 0 | 22.57M | 72.17M | 108.87M | 107.13M |
| Other Non-Current Assets | 522K | 1.69M | 902K | 967K | 3.55M | 6.57M | 194.43M | 18.37M |
| Total Assets | 89.28M | 106.7M | 427.07M | 433.44M | 673.87M | 811.45M | 999.2M | 1.27B |
| Asset Turnover | - | 0.06x | 0.37x | 0.70x | 0.65x | 0.72x | 0.72x | 0.68x |
| Asset Growth % | - | 19.51% | 300.25% | 1.49% | 55.47% | 20.42% | 23.14% | 27.26% |
| Total Current Liabilities | 7.23M | 19.89M | 134.54M | 53.77M | 78.88M | 163.78M | 175.08M | 252.13M |
| Accounts Payable | 1.46M | 6.36M | 2.56M | 1M | 3.79M | 17.73M | 13.74M | 0 |
| Days Payables Outstanding | 2.9K | 1.47K | 33.63 | 6.58 | 16.55 | 53.38 | 31.99 | - |
| Short-Term Debt | 0 | 0 | 0 | 2M | 2M | 15M | 16.25M | 20M |
| Deferred Revenue (Current) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 313K | 753K | 100.31M | 1 | 1.62M | 107.3M | 4.35M | 232.13M |
| Current Ratio | 11.99x | 1.58x | 1.95x | 5.29x | 5.07x | 2.75x | 3.31x | 3.60x |
| Quick Ratio | 11.99x | 1.53x | 1.93x | 5.21x | 5.02x | 2.72x | 3.27x | 3.58x |
| Cash Conversion Cycle | - | -961.15 | 67.34 | 64.19 | 47.87 | 9.26 | 27.17 | - |
| Total Non-Current Liabilities | 523K | 98.4M | 195.35M | 193.16M | 192.15M | 180.68M | 164.96M | 149.28M |
| Long-Term Debt | 324.2M | 97.95M | 194.25M | 189.98M | 189.65M | 178.57M | 163.02M | 0 |
| Capital Lease Obligations | 0 | 0 | 0 | 2.4M | 0 | 0 | 822K | 0 |
| Deferred Tax Liabilities | -324.46M | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | -323.68M | 450K | 1.1M | 777K | 2.5M | 2.11M | 1.13M | 149.28M |
| Total Liabilities | 7.75M | 118.29M | 329.89M | 246.94M | 271.03M | 344.46M | 340.05M | 401.41M |
| Total Debt | 324.2M | 97.95M | 194.25M | 195.74M | 191.65M | 193.57M | 181.41M | 20M |
| Net Debt | 240.68M | 73.49M | -34.38M | -38.56M | -52.14M | -118.09M | -271.6M | -732.5M |
| Debt / Equity | 3.98x | - | 2.00x | 1.05x | 0.48x | 0.41x | 0.28x | 0.02x |
| Debt / EBITDA | - | - | 7.14x | 1.84x | 1.33x | 0.89x | 0.84x | 0.09x |
| Net Debt / EBITDA | - | - | -1.26x | -0.36x | -0.36x | -0.55x | -1.26x | -3.15x |
| Interest Coverage | - | -24.03x | 0.60x | 3.62x | 6.39x | 8.08x | 10.91x | 14.23x |
| Total Equity | 81.53M | -11.59M | 97.18M | 186.51M | 402.84M | 466.99M | 659.15M | 870.22M |
| Equity Growth % | - | -114.21% | 938.84% | 91.92% | 115.99% | 15.93% | 41.15% | 32.02% |
| Book Value per Share | 1.66 | -0.18 | 1.68 | 3.15 | 6.59 | 7.74 | 11.39 | 14.86 |
| Total Shareholders' Equity | 81.53M | -11.59M | 97.18M | 186.51M | 402.84M | 466.99M | 659.15M | 870.22M |
| Common Stock | 1K | 0 | 1K | 1K | 1K | 1K | 1K | 1K |
| Retained Earnings | -242.67M | -422.86M | -488.19M | -453.6M | -272.13M | -143.28M | 2.22M | 160.9M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -2K | 0 | 0 | 0 | -151K | 2K | 66K | 346K |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -38.8M | -75.44M | -2.98M | 98.56M | 144.47M | 219.39M | 219.82M | 348.2M |
| Operating CF Margin % | - | -1258.32% | -1.87% | 32.27% | 32.99% | 37.69% | 30.76% | 40.09% |
| Operating CF Growth % | - | -94.43% | 96.04% | 3401.74% | 46.58% | 51.86% | 0.2% | 58.4% |
| Net Income | -39.9M | -151.98M | -36.94M | 34.6M | 181.47M | 128.85M | 145.49M | 0 |
| Depreciation & Amortization | 184K | 3.8M | 10.24M | 21.08M | 25.05M | 24.36M | 24.11M | 0 |
| Stock-Based Compensation | 1.08M | 9.91M | 4.69M | 16.11M | 26.91M | 31.7M | 42.6M | 0 |
| Deferred Taxes | 0 | 0 | 25.75M | 0 | 0 | -13.42M | -29.3M | 0 |
| Other Non-Cash Items | 2.06M | 59.44M | 4.91M | 24.59M | -82.06M | 12.85M | 44.23M | 256.38M |
| Working Capital Changes | -164K | 3.39M | -11.63M | 2.19M | -6.89M | 35.03M | -7.32M | 91.82M |
| Change in Receivables | 0 | -4.25M | -17.92M | -12.67M | -19.9M | -19.4M | -8.89M | -13.75M |
| Change in Inventory | 0 | -1.09M | -2.73M | -609K | 135K | -1.07M | -1.83M | 1.84M |
| Change in Payables | -610K | 0 | -3.8M | 0 | 0 | 8.95M | -5.38M | 3.95M |
| Cash from Investing | -1.34M | -127.15M | -2M | -100.3M | -141.83M | -46.44M | -67.48M | -39.65M |
| Capital Expenditures | -1.34M | -149K | -2M | -298K | -172K | -312K | -1.15M | 0 |
| CapEx % of Revenue | - | 2.49% | 1.25% | 0.1% | 0.04% | 0.05% | 0.16% | 0.04% |
| Acquisitions | 0 | 0 | -2M | 0 | 0 | -36.97M | -33.07M | 0 |
| Investments | - | - | - | - | - | - | - | - |
| Other Investing | 0 | -127M | 2M | -100M | -141.66M | 0 | -26.5M | -39.65M |
| Cash from Financing | 21.61M | 143.77M | 209.16M | 7.42M | 6.84M | -105.55M | -11M | -9.05M |
| Debt Issued (Net) | 0 | 100M | 79.42M | -500K | -2M | -1.25M | -15M | -16.25M |
| Equity Issued (Net) | 1000K | 0 | -184K | 0 | 0 | -1000K | 1000K | 1000K |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -3.2M | 0 | -167K | 0 | 0 | -100M | 0 | 0 |
| Other Financing | -185K | 43.77M | 129.93M | 7.92M | 8.84M | -3.79M | -2.5M | -3M |
| Net Change in Cash | -18.53M | -58.82M | 204.17M | 5.68M | 9.47M | 67.4M | 141.34M | 299.5M |
| Free Cash Flow | -40.14M | -75.58M | -4.99M | 98.26M | 144.29M | 219.07M | 218.67M | 347.89M |
| FCF Margin % | - | -1260.8% | -3.12% | 32.17% | 32.95% | 37.64% | 30.59% | 40.06% |
| FCF Growth % | - | -88.3% | 93.4% | 2070.3% | 46.85% | 51.83% | -0.19% | 59.09% |
| FCF per Share | -0.82 | -1.19 | -0.09 | 1.66 | 2.36 | 3.63 | 3.78 | 5.94 |
| FCF Conversion (FCF/Net Income) | 0.97x | 0.50x | 0.08x | 2.85x | 0.80x | 1.70x | 1.51x | 2.19x |
| Interest Paid | 0 | 4.23M | 0 | 19.83M | 16.36M | 20.05M | 17.32M | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 48.23M | 79.64M | 0 |
| Metric | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -48.94% | -434.57% | -86.32% | 24.39% | 61.58% | 29.63% | 25.84% | 20.75% |
| Return on Invested Capital (ROIC) | - | -56.98% | 20.43% | 62.3% | 36.15% | 41.17% | 38.87% | 59.53% |
| Gross Margin | - | 73.69% | 82.64% | 81.82% | 80.93% | 79.17% | 78.06% | 77.16% |
| Net Margin | - | -2535.06% | -23.13% | 11.33% | 41.44% | 22.14% | 20.36% | 18.27% |
| Debt / Equity | 3.98x | - | 2.00x | 1.05x | 0.48x | 0.41x | 0.28x | 0.02x |
| Interest Coverage | - | -24.03x | 0.60x | 3.62x | 6.39x | 8.08x | 10.91x | 14.23x |
| FCF Conversion | 0.97x | 0.50x | 0.08x | 2.85x | 0.80x | 1.70x | 1.51x | 2.19x |
| Revenue Growth | - | - | 2564.59% | 91.21% | 43.35% | 32.93% | 22.8% | 21.51% |
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