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PRTC logoPureTech Health plc(PRTC)Earnings, Financials & Key Ratios

PRTC•NASDAQ
$17.01
$41M mkt cap·Price updated May 6, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryDrug Discovery and Antibody Platforms
AboutPureTech Health plc, a clinical-stage biotherapeutics company, discovers, develops, and commercializes medicines for inflammatory, fibrotic and immunological, intractable cancers, lymphatic and gastrointestinal, neurological and neuropsychological, and other diseases in the United States. The company offers KarXT targeting muscarinic acetylcholine receptors to treat schizophrenia and psychosis in Alzheimer's disease; a regenerative biology platform for androgenetic alopecia, epithelial ageing, and other medical conditions; an immunomodulation platform to treat chronic and acute inflammatory disorders; oral therapies based on defined consortia of bacteria is isolated from the human microbiome; and therapies to treat cognitive dysfunction associated with depression, multiple sclerosis, post COVID and ICU, and cancer related conditions. It also provides hematopoietic stem cell based therapies for patients with blood cancer; a voice-based technology platform to detect voice changes linked to health conditions; and a technology platform for the oral delivery of biologics, vaccines, and other drugs. In addition, the company is developing LYT-100 to treat lymphedema, and other lymphatic flow disorders; LYT-200, a IgG4 monoclonal antibody to target galectin-9; LYT-210 to treat solid tumors; Glyph, a synthetic lymphatic targeting chemistry platform; Orasome technology to enable the oral administration of macromolecule therapeutic payloads; meningeal lymphatics platform to treat Alzheimer's and Parkinson's diseases; and Alivio technology platform for inflammation-targeted disease immunomodulation. PureTech Health plc has collaboration and license agreements with Boehringer Ingelheim International GMBH; Eli Lilly and Company; Imbrium Therapeutics L.P.; and Shionogi & Co., Ltd. The company was incorporated in 2015 and is headquartered in Boston, Massachusetts.Show more
  • Revenue$5M-3.5%
  • EBITDA-$95M+28.2%
  • Net Income-$110M-305.1%
  • EPS (Diluted)-46.00-2400.0%
  • Gross Margin100%+284.1%
  • EBITDA Margin-2042.84%+25.6%
  • Operating Margin-2114.72%+25.0%
  • Net Margin-2355.42%-312.5%
  • ROE-30.76%-348.9%
  • ROIC-66.87%-44.8%
  • Debt/Equity0.06+17.9%
  • Interest Coverage-1.42-142.2%
Technical→

PRTC Key Insights

PureTech Health plc (PRTC) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Share count reduced 91.1% through buybacks
  • ✓Trading at only 0.1x book value

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Sales declining 11.0% over 5 years
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

PRTC Price & Volume

PureTech Health plc (PRTC) stock price & volume — 10-year historical chart

Loading chart...

PRTC Growth Metrics

PureTech Health plc (PRTC) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-8.83%
5 Years-10.99%
3 Years30.63%
TTM-53.72%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM52.07%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-1176.19%

Return on Capital

10 Years-44.32%
5 Years-22.86%
3 Years-21.6%
Last Year-18.77%

PRTC Recent Earnings

PureTech Health plc (PRTC) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (80%)●Beat Revenue 3/12 qtrs (30%)
Q2 2026Latest
Apr 29, 2026
EPS
$26.90
Est $1.94
-1286.6%
Revenue
$3M
Est $2M
+47.2%
Q3 2025
Aug 28, 2025
EPS
$1.86
Est $2.04
+8.9%
Revenue
$2M
Est $27M
-93.2%
Q2 2025
Apr 30, 2025
EPS
$0.35
Est $2.83
+112.5%
Revenue
$4M
Est $30M
-86.7%
Q3 2024
Aug 28, 2024
EPS
$0.15
Est $3.03
+94.9%
Revenue
$288,000
Est $8M
-96.2%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestApr 29, 2026
$26.90vs $1.94-1286.6%
$3Mvs $2M+47.2%
Q3 2025Aug 28, 2025
$1.86vs $2.04+8.9%
$2Mvs $27M-93.2%
Q2 2025Apr 30, 2025
$0.35vs $2.83+112.5%
$4Mvs $30M-86.7%
Q3 2024Aug 28, 2024
$0.15vs $3.03+94.9%
$288,000vs $8M-96.2%
Based on last 12 quarters of dataView full earnings history →

PRTC Peer Comparison

PureTech Health plc (PRTC) competitors in Drug Discovery and Antibody Platforms — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ROIV logoROIVRoivant Sciences Ltd.Direct Competitor20.91B28.82-120.08-11.19%-60.8%-16.27%0.02
ATAI logoATAIAtai Beckley N.VDirect Competitor1B4.17-4.48-1.91%-51.09%-96.43%0.21
CMPS logoCMPSCOMPASS Pathways plcDirect Competitor937.8M9.76-3.17-335.93%
RXRX logoRXRXRecursion Pharmaceuticals, Inc.Direct Competitor1.53B3.43-2.3826.92%-8.44%-54.32%0.07
ABSI logoABSIAbsci CorporationDirect Competitor924.91M5.95-7.08-38.24%-41.14%-59.68%0.03
ACAD logoACADACADIA Pharmaceuticals Inc.Product Competitor3.68B21.489.3811.87%36.49%41.9%0.04
INVA logoINVAInnoviva, Inc.Product Competitor1.91B22.526.8218.52%118.91%46.47%0.23
PRTA logoPRTAProthena Corporation plcProduct Competitor601.85M11.18-2.47-92.84%-25.21%-73%0.05

Compare PRTC vs Peers

PureTech Health plc (PRTC) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ROIV

Most directly comparable listed peer for PRTC.

Scale Benchmark

vs JNJ

Larger-name benchmark to compare PRTC against a more recognizable public peer.

Peer Set

Compare Top 5

vs ROIV, ATAI, CMPS, RXRX

PRTC Income Statement

PureTech Health plc (PRTC) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Sales/Revenue650K16.37M8.69M8.34M9.98M2.09M3.33M4.83M4.66M
Revenue Growth %-85.33%2418.62%-46.93%-3.99%19.64%-79.06%59.33%44.98%-3.5%
Cost of Goods Sold71.03M77.4M85.85M0110.47M152.43M4.93M00
COGS % of Revenue10928.46%472.8%988.12%-1107.03%7293.44%148.14%--
Gross Profit
-70.39M▲ 0%
-61.03M▲ 13.3%
-77.16M▼ 26.4%
8.34M▲ 110.8%
-100.49M▼ 1304.8%
-136.81M▼ 36.1%
-1.6M▲ 98.8%
1.26M▲ 178.4%
4.66M▲ 270.6%
Gross Margin %-10828.46%-372.8%-888.12%100%-1007.03%-6546.17%-48.14%26.04%100%
Gross Profit Growth %-2560.15%13.29%-26.43%110.81%-1304.8%-36.15%98.83%178.42%270.64%
Operating Expenses116.07M120.39M144.09M127.87M160.26M60.99M54.55M140.41M103.18M
OpEx % of Revenue17856.92%735.39%1658.46%1533.05%1605.99%2918.28%1638.26%2908.24%2214.72%
Selling, General & Admin46.28M24.43M34.89M26.5M30.76M35.67M48.36M27.49M20.65M
SG&A % of Revenue7120.46%149.2%401.59%317.67%308.26%1706.65%1452.31%569.41%443.29%
Research & Development71.67M57.29M65.17M61.19M81.52M116.11M96.23M54.28M45.74M
R&D % of Revenue11026.46%349.97%750.07%733.56%816.93%5555.65%2889.94%1124.28%981.82%
Other Operating Expenses14K-278K44.03M40.19M47.98M-90.79M-90.04M58.64M36.79M
Operating Income
-115.42M▲ 0%
-104.02M▲ 9.9%
-135.4M▼ 30.2%
-119.53M▲ 11.7%
-150.28M▼ 25.7%
-197.81M▼ 31.6%
-146.2M▲ 26.1%
-136.09M▲ 6.9%
-98.53M▲ 27.6%
Operating Margin %-17756.92%-635.39%-1558.46%-1433.05%-1505.98%-9464.45%-4390.36%-2818.87%-2114.72%
Operating Income Growth %-56.12%9.88%-30.17%11.72%-25.73%-31.62%26.09%6.91%27.61%
EBITDA-113.32M-101.24M-128.73M-112.88M-143.04M-188.91M-141.27M-132.52M-95.18M
EBITDA Margin %-17434%-618.42%-1481.74%-1353.27%-1433.45%-9038.95%-4242.22%-2744.9%-2042.84%
EBITDA Growth %-56.61%10.66%-27.16%12.32%-26.73%-32.07%25.22%6.19%28.18%
D&A (Non-Cash Add-back)2.1M2.78M6.67M6.66M7.24M8.89M4.93M3.57M3.35M
EBIT-70.01M-68.05M481.12M56.03M19.46M-197.81M-16.56M33.81M-65.15M
Net Interest Income-8.46M-11.45M260K-1.76M-4.5M1.85M2.52M12.63M-32.73M
Interest Income1.75M3.36M4.36M1.18M214K5.8M16.01M22.67M13.05M
Interest Expense10.21M14.81M4.1M2.95M4.71M3.95M13.49M10.04M45.78M
Other Income/Expense44.71M35.58M613.87M138.5M91.33M105.02M110.1M159.87M-12.4M
Pretax Income
-70.71M▲ 0%
-68.44M▲ 3.2%
478.47M▲ 799.1%
18.97M▼ 96.0%
-58.95M▼ 410.8%
-92.78M▼ 57.4%
-36.1M▲ 61.1%
23.77M▲ 165.9%
-110.93M▼ 566.6%
Pretax Margin %-10878.62%-418.04%5507.3%227.42%-590.77%-4439.38%-1084.17%492.42%-2380.92%
Income Tax-14K2.22M112.41M14.4M3.76M-55.72M30.52M-4.01M-842K
Effective Tax Rate %0.02%-3.25%23.49%75.92%-6.37%60.05%-84.55%-16.86%0.76%
Net Income
30.87M▲ 0%
-43.65M▼ 241.4%
421.14M▲ 1064.7%
5.99M▼ 98.6%
-60.56M▼ 1111.8%
-50.35M▲ 16.8%
-65.7M▼ 30.5%
53.51M▲ 181.4%
-109.74M▼ 305.1%
Net Margin %4749.08%-266.65%4847.42%71.75%-606.85%-2409.33%-1972.88%1108.33%-2355.42%
Net Income Growth %163.27%-241.42%1064.73%-98.58%-1111.83%16.85%-30.47%181.45%-305.08%
Net Income (Continuing)-57.49M-70.66M335.27M4.57M-62.71M-37.06M-66.63M27.78M-110.08M
Discontinued Operations000000000
Minority Interest-150.31M-108.53M-17.64M-16.21M-9.37M5.37M-5.83M-6.77M-6.4M
EPS (Diluted)
1.10▲ 0%
-1.60▼ 245.5%
14.40▲ 1000.0%
0.20▼ 98.6%
-2.10▼ 1150.0%
-1.80▲ 14.3%
-2.40▼ 33.3%
2.00▲ 183.3%
-46.00▼ 2400.0%
EPS Growth %152.38%-245.45%1000%-98.61%-1150%14.29%-33.33%183.33%-2400%
EPS (Basic)1.10-1.6014.900.20-2.10-1.80-2.402.00-46.00
Diluted Shares Outstanding23.89M27.38M29.18M29.29M28.66M28.48M27.63M26.97M2.41M
Basic Shares Outstanding24.07M27.28M29.25M29.93M28.66M27.97M27.63M26.97M2.41M
Dividend Payout Ratio0.29%-0.03%------

PRTC Balance Sheet

PureTech Health plc (PRTC) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Total Current Assets198.11M259.79M168.84M414.35M501.81M386.19M347.2M386.26M305.02M
Cash & Short-Term Investments189.67M250.88M162.45M403.88M465.71M350.1M327.14M367.31M278.89M
Cash Only72.65M117.05M132.36M403.88M465.71M149.87M191.08M280.64M254.07M
Short-Term Investments117.03M133.83M30.09M00200.23M136.06M86.67M24.83M
Accounts Receivable1.8M1.33M2.33M2.94M3.59M22.36M2.38M12.9M8.13M
Days Sales Outstanding1.01K29.6197.76128.61131.273.9K260.43975.48636.93
Inventory-2.72M-1.33M0028M0000
Days Inventory Outstanding----92.51----
Other Current Assets927K2.2M2.12M2.12M-6.24M2.12M13.37M1.64M11.42M
Total Non-Current Assets141.74M181.98M772.33M575.64M444.2M316.45M346.77M216.38M229.69M
Property, Plant & Equipment6.86M8.32M43.84M42.87M43.94M37.24M19.36M15.13M11.5M
Fixed Asset Turnover0.09x1.97x0.20x0.19x0.23x0.06x0.17x0.32x0.41x
Goodwill00000000601K
Intangible Assets3.31M3.08M625K899K987K831K906K601K0
Long-Term Investments14.33M35.93M695.46M531.86M398.46M60.81M325.63M200.17M217.43M
Other Non-Current Assets117.1M134.2M32.27M531.87M399.27M278.38M879K476K166K
Total Assets
339.85M▲ 0%
441.76M▲ 30.0%
941.18M▲ 113.1%
989.99M▲ 5.2%
946.01M▼ 4.4%
702.65M▼ 25.7%
693.97M▼ 1.2%
602.63M▼ 13.2%
534.71M▼ 11.3%
Asset Turnover0.00x0.04x0.01x0.01x0.01x0.00x0.00x0.01x0.01x
Asset Growth %13.76%29.99%113.05%5.19%-4.44%-25.72%-1.23%-13.16%-11.27%
Total Current Liabilities273.86M265.76M139.2M180.92M226.13M96.89M51.37M41.39M46.31M
Accounts Payable3.39M4.64M11.1M8.87M11.35M26.5M14.64M5.52M3.07M
Days Payables Outstanding17.4421.947.19-37.4863.461.08K--
Short-Term Debt7.46M12.01M1.46M26.45M5.5M7.5M3.7M4.11M8.67M
Deferred Revenue (Current)129.01M30.8M22.21M141.61M31.32M2.19M-29.47M00
Other Current Liabilities121.04M207.08M92.45M-529K152.01M29.4M29.64M27.18M31.54M
Current Ratio0.72x0.98x1.21x2.29x2.22x3.99x6.76x9.33x6.59x
Quick Ratio0.73x0.98x1.21x2.29x2.10x3.99x6.76x9.33x6.59x
Cash Conversion Cycle----186.3----
Total Non-Current Liabilities1.99M9.03M151.58M155.53M135.72M58.17M184.37M153.31M182.73M
Long-Term Debt0357K014.82M14.26M10.24M000
Capital Lease Obligations410K357K34.91M32.09M29.04M24.16M18.25M14.67M11.09M
Deferred Tax Liabilities4.4M6.43M115.44M108.63M89.77M19.64M52.46M00
Other Non-Current Liabilities1.42M876K0-1K2.66M4.13M113.66M138.64M171.64M
Total Liabilities275.85M274.79M290.78M336.45M361.86M155.06M235.74M194.7M229.03M
Total Debt7.46M12.37M39.3M76.62M52.75M46.87M25.34M22.36M19.76M
Net Debt-65.19M-104.68M-93.06M-327.26M-413.68M-102.99M-165.74M-258.28M-234.31M
Debt / Equity0.12x0.07x0.06x0.12x0.09x0.09x0.06x0.05x0.06x
Debt / EBITDA---------
Net Debt / EBITDA---------
Interest Coverage-6.85x-4.60x117.29x19.02x4.13x-50.04x-1.23x3.37x-1.42x
Total Equity
64M▲ 0%
166.97M▲ 160.9%
650.4M▲ 289.5%
653.54M▲ 0.5%
584.15M▼ 10.6%
547.59M▼ 6.3%
458.23M▼ 16.3%
407.93M▼ 11.0%
305.68M▼ 25.1%
Equity Growth %-30.75%160.91%289.53%0.48%-10.62%-6.26%-16.32%-10.98%-25.07%
Book Value per Share2.686.1022.2922.3220.3819.2316.5815.13126.95
Total Shareholders' Equity214.3M275.51M668.04M669.75M593.51M542.22M464.07M414.71M312.07M
Common Stock4.68M5.38M5.41M5.42M5.44M5.46M5.46M4.86M4.86M
Retained Earnings-127.87M-167.69M254.44M260.43M199.87M149.52M83.82M32.49M61.27M
Treasury Stock00000-26.49M-44.63M-46.86M-41.15M
Accumulated OCI-3.88M-6.07M-18.28M-23.58M-39.61M-14.39M129.15M133.96M182K
Minority Interest-150.31M-108.53M-17.64M-16.21M-9.37M5.37M-5.83M-6.77M-6.4M

PRTC Cash Flow Statement

PureTech Health plc (PRTC) cash flow — operating, investing & free cash flow history

Line itemDec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25
Cash from Operations-88.69M-72.8M-98.16M-131.83M-158.27M-178.79M-105.92M-134.37M-85.33M
Operating CF Margin %-13644.31%-444.66%-1129.79%-1580.47%-1586.07%-8554.64%-3180.69%-2783.12%-1831.51%
Operating CF Growth %-52.82%17.92%-34.84%-34.3%-20.06%-12.96%40.76%-26.86%36.5%
Net Income-70.7M-70.66M366.06M4.57M-62.71M-37.06M-65.7M27.78M-110M
Depreciation & Amortization2.1M2.78M6.67M6.64M7.29M8.89M4.93M3.57M3.36M
Stock-Based Compensation11.85M12.64M14.47M10.72M13.95M14.7M4.42M22.85M0
Deferred Taxes-116.81M-19.42M-546.61M-151.35M-112.61M-70.12M00-2.74M
Other Non-Cash Items81.9M-8.1M46.23M6.11M-5.05M-111.12M-67.09M-178.34M27.18M
Working Capital Changes2.97M9.96M15.03M-8.53M861K15.92M17.52M-10.24M-3.13M
Change in Receivables-1.67M467K747K-529K-617K-7.73M9.75M629K-236.55K
Change in Inventory0000-103K0000
Change in Payables5.24M5.09M11.17M605K8.34M22.03M3.84M-9.7M-1.03M
Cash from Investing83.68M-39.65M63.66M364.48M197.38M-107.22M68.99M240.89M63.44M
Capital Expenditures-2.17M-4.49M-12.54M-5.42M-5.66M-2.18M-245K-11K-6.01K
CapEx % of Revenue334%27.43%144.31%65.03%56.73%104.11%7.36%0.23%0.13%
Acquisitions-16.34M-13.39M-16.04M-10M321K-20.44M-13.78M-105.97M269.63K
Investments---------
Other Investing-16.34M125K191K350K-14.91M416K865K255K49.11K
Cash from Financing14.7M156.89M49.91M38.87M22.73M-29.83M78.14M-16.96M-6.34M
Debt Issued (Net)2.45M5.96M1.43M39.79M2.21M393K-3.34M-3.39M0
Equity Issued (Net)12.33M-35K50.27M1.99M-13.33M-26.15M-18.5M-106.66M-1.95M
Dividends Paid-91K-8K-112K000000
Share Repurchases-66K-35K-1.28M00-26.49M-19.65M-107.56M-2.06M
Other Financing0150.96M-1.68M-2.91M33.84M-4.07M99.98M93.1M-4.39M
Net Change in Cash
9.69M▲ 0%
44.4M▲ 358.2%
15.31M▼ 65.5%
271.52M▲ 1673.6%
61.83M▼ 77.2%
-315.84M▼ 610.8%
41.22M▲ 113.0%
89.56M▲ 117.3%
-28.22M▼ 131.5%
Free Cash Flow
-90.86M▲ 0%
-77.29M▲ 14.9%
-110.69M▼ 43.2%
-137.25M▼ 24.0%
-163.94M▼ 19.4%
-180.97M▼ 10.4%
-106.16M▲ 41.3%
-134.38M▼ 26.6%
-85.34M▲ 36.5%
FCF Margin %-13978.31%-472.09%-1274.1%-1645.5%-1642.8%-8658.76%-3188.05%-2783.35%-1831.64%
FCF Growth %-47.24%14.94%-43.23%-23.99%-19.44%-10.39%41.34%-26.58%36.5%
FCF per Share-3.80-2.82-3.79-4.69-5.72-6.36-3.84-4.98-35.44
FCF Conversion (FCF/Net Income)-2.87x1.67x-0.23x-22.03x2.61x3.55x1.61x-2.51x0.78x
Interest Paid000000000
Taxes Paid000000000

PRTC Key Ratios

PureTech Health plc (PRTC) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-38.05%39.47%-37.8%103.05%0.92%-9.79%-8.9%-13.06%12.36%-30.76%
Return on Invested Capital (ROIC)-156.94%-491.73%-255.4%-32.78%-20.29%-45.31%-48.18%-29.75%-46.17%-66.87%
Gross Margin64.57%-10828.46%-372.8%-888.12%100%-1007.03%-6546.17%-48.14%26.04%100%
Net Margin-1101.15%4749.08%-266.65%4847.42%71.75%-606.85%-2409.33%-1972.88%1108.33%-2355.42%
Debt / Equity0.08x0.12x0.07x0.06x0.12x0.09x0.09x0.06x0.05x0.06x
Interest Coverage-11.22x-6.85x-4.60x117.29x19.02x4.13x-50.04x-1.23x3.37x-1.42x
FCF Conversion1.19x-2.87x1.67x-0.23x-22.03x2.61x3.55x1.61x-2.51x0.78x
Revenue Growth-62.26%-85.33%2418.62%-46.93%-3.99%19.64%-79.06%59.33%44.98%-3.5%

PRTC Frequently Asked Questions

PureTech Health plc (PRTC) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

PureTech Health plc (PRTC) reported $9.0M in revenue for fiscal year 2025. This represents a 13% increase from $7.9M in 2012.

PureTech Health plc (PRTC) saw revenue decline by 3.5% over the past year.

PureTech Health plc (PRTC) reported a net loss of $56.0M for fiscal year 2025.

Dividend & Returns

PureTech Health plc (PRTC) has a return on equity (ROE) of -30.8%. Negative ROE indicates the company is unprofitable.

PureTech Health plc (PRTC) had negative free cash flow of $218.8M in fiscal year 2025, likely due to heavy capital investments.

Explore More PRTC

PureTech Health plc (PRTC) financial analysis — history, returns, DCA and operating performance tools

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Financial Ratios

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Valuation

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