No significant weaknesses identified
| Name | Market Cap | Current Price | P/E Ratio | Revenue Growth 1Y | Net Margin | ROE | FCF Yield | Debt/Equity |
|---|---|---|---|---|---|---|---|---|
| CORTCorcept Therapeutics Incorporated | 3.78B | 35.70 | 43.54 | 12.79% | 13.01% | 15.3% | 3.75% | 0.01 |
| BMRNBioMarin Pharmaceutical Inc. | 11.86B | 61.73 | 34.29 | 10.83% | 5.73% | 6.11% | 0.10 | |
| VRTXVertex Pharmaceuticals Incorporated | 126.19B | 496.83 | 32.43 | 8.9% | 31.35% | 21.22% | 2.53% | 0.20 |
| CPRXCatalyst Pharmaceuticals, Inc. | 2.83B | 23.08 | 13.74 | 19.78% | 36.39% | 22.46% | 7.38% | 0.00 |
| HRMYHarmony Biosciences Holdings, Inc. | 1.65B | 28.54 | 10.53 | 21.51% | 18.27% | 18.24% | 21.12% | 0.02 |
| PTCTPTC Therapeutics, Inc. | 5.45B | 68.19 | 8.76 | 114.51% | 42.25% | |||
| BCRXBioCryst Pharmaceuticals, Inc. | 1.86B | 8.75 | 7.23 | 94.1% | 30.16% | 18.63% | ||
| RAREUltragenyx Pharmaceutical Inc. | 2.26B | 23.39 | -3.72 | 29.01% | -91.95% | -35.88% | 0.15 |
Analyze head-to-head performance against top industry competitors across valuation, growth, and profitability metrics.
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Sales/Revenue | 0 | 0 | 500K | 102.31M | 119.07M | 140.83M | 214.2M | 398.2M | 491.73M | 588.99M |
| Revenue Growth % | - | - | - | 20361.2% | 16.39% | 18.27% | 52.1% | 85.9% | 23.49% | 19.78% |
| Cost of Goods Sold | 43.41K | 45.69K | 19.92M | 14.76M | 17.04M | 21.88M | 34.39M | 51.97M | 68.84M | 87.25M |
| COGS % of Revenue | - | - | 3983.84% | 14.43% | 14.31% | 15.54% | 16.06% | 13.05% | 14% | 14.81% |
| Gross Profit | -43.41K | -45.69K | -19.42M | 87.55M | 102.03M | 118.95M | 179.81M | 346.24M | 422.89M | 501.74M |
| Gross Margin % | - | - | -3883.84% | 85.57% | 85.69% | 84.46% | 83.94% | 86.95% | 86% | 85.19% |
| Gross Profit Growth % | -25.93% | -5.26% | -42403.02% | 550.83% | 16.55% | 16.58% | 51.17% | 92.56% | 22.14% | 18.64% |
| Operating Expenses | 19.28M | 18.68M | 35.8M | 55.72M | 60.73M | 66.56M | 77.97M | 259.43M | 227.76M | 243.96M |
| OpEx % of Revenue | - | - | 7159.03% | 54.47% | 51% | 47.26% | 36.4% | 65.15% | 46.32% | 41.42% |
| Selling, General & Admin | 7.91M | 7.3M | 15.88M | 36.88M | 44.23M | 49.63M | 57.09M | 133.71M | 177.74M | 193.75M |
| SG&A % of Revenue | - | - | 3175.19% | 36.05% | 37.15% | 35.24% | 26.65% | 33.58% | 36.15% | 32.9% |
| Research & Development | 11.37M | 11.38M | 19.92M | 18.84M | 16.5M | 16.94M | 19.79M | 93.15M | 12.65M | 12.71M |
| R&D % of Revenue | - | - | 3983.84% | 18.42% | 13.85% | 12.03% | 9.24% | 23.39% | 2.57% | 2.16% |
| Other Operating Expenses | 0 | 0 | 1.29M | 0 | 0 | 0 | 1.1M | 32.56M | 37.38M | 37.5M |
| Operating Income | -19.28M | -18.68M | -35.3M | 31.82M | 41.3M | 52.38M | 101.84M | 86.81M | 195.12M | 257.78M |
| Operating Margin % | - | - | -7059.03% | 31.11% | 34.69% | 37.2% | 47.54% | 21.8% | 39.68% | 43.77% |
| Operating Income Growth % | 5.48% | 3.11% | -88.95% | 190.16% | 29.79% | 26.83% | 94.4% | -14.75% | 124.77% | 32.11% |
| EBITDA | -19.24M | -18.63M | -35.26M | 31.88M | 41.4M | 52.58M | 103.08M | 119.69M | 232.9M | 295.28M |
| EBITDA Margin % | - | - | -7051.44% | 31.16% | 34.76% | 37.33% | 48.12% | 30.06% | 47.36% | 50.13% |
| EBITDA Growth % | 5.53% | 3.13% | -89.21% | 190.42% | 29.85% | 27.01% | 96.05% | 16.12% | 94.58% | 26.78% |
| D&A (Non-Cash Add-back) | 43.41K | 45.69K | 37.98K | 55K | 92K | 192K | 1.24M | 32.88M | 37.77M | 37.5M |
| EBIT | -18.07M | -18.41M | -35.3M | 31.82M | 41.3M | 52.38M | 101.84M | 86.81M | 195.12M | 257.78M |
| Net Interest Income | 0 | 0 | 1.29M | 1.59M | 0 | 0 | 0 | 0 | 16.06M | 0 |
| Interest Income | 321.61K | 454.16K | 1.29M | 1.59M | 0 | 0 | 0 | 0 | 16.06M | 0 |
| Interest Expense | 321.61K | 454.16K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Income/Expense | 1.21M | 267.26K | 1.29M | 1.59M | 587K | 282K | 2.88M | 7.7M | 21.14M | 25.74M |
| Pretax Income | -18.07M | -18.41M | -34M | 33.41M | 41.89M | 52.67M | 104.72M | 94.51M | 216.26M | 283.51M |
| Pretax Margin % | - | - | -6800.7% | 32.66% | 35.18% | 37.4% | 48.89% | 23.73% | 43.98% | 48.14% |
| Income Tax | 0 | 141.22K | 0 | 1.53M | -33.09M | 13.19M | 21.64M | 23.1M | 52.37M | 69.19M |
| Effective Tax Rate % | 100% | 100% | 100% | 95.41% | 179% | 74.97% | 79.34% | 75.56% | 75.78% | 75.6% |
| Net Income | -18.07M | -18.41M | -34M | 31.88M | 74.98M | 39.48M | 83.08M | 71.41M | 163.89M | 214.33M |
| Net Margin % | - | - | -6800.7% | 31.16% | 62.97% | 28.03% | 38.79% | 17.93% | 33.33% | 36.39% |
| Net Income Growth % | 10.68% | -1.88% | -84.68% | 193.74% | 135.24% | -47.35% | 110.42% | -14.05% | 129.5% | 30.78% |
| Net Income (Continuing) | -18.07M | -18.41M | -34M | 31.88M | 74.98M | 39.48M | 83.08M | 71.41M | 163.89M | 214.33M |
| Discontinued Operations | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| EPS (Diluted) | -0.22 | -0.21 | -0.33 | 0.30 | 0.71 | 0.37 | 0.75 | 0.63 | 1.31 | 1.68 |
| EPS Growth % | 12% | 4.55% | -57.14% | 190.91% | 136.67% | -47.89% | 102.7% | -16% | 107.94% | 28.24% |
| EPS (Basic) | -0.22 | -0.21 | -0.33 | 0.31 | 0.72 | 0.38 | 0.80 | 0.67 | 1.38 | 1.75 |
| Diluted Shares Outstanding | 82.88M | 85.8M | 102.63M | 106.02M | 106.24M | 107.8M | 111.38M | 113.75M | 124.94M | 127.26M |
| Basic Shares Outstanding | 82.88M | 85.8M | 102.63M | 102.94M | 103.51M | 103.38M | 103.37M | 106.28M | 118.46M | 122.29M |
| Dividend Payout Ratio | - | - | - | - | - | - | - | - | - | - |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Total Current Assets | 41.45M | 85.19M | 55.19M | 111.36M | 159.24M | 210.11M | 320.81M | 219.33M | 623.61M | 894.03M |
| Cash & Short-Term Investments | 40.41M | 84.01M | 53.48M | 94.52M | 140.28M | 191.27M | 298.39M | 137.64M | 517.55M | 709.17M |
| Cash Only | 13.89M | 57.5M | 16.56M | 89.51M | 130.24M | 171.44M | 298.39M | 137.64M | 517.55M | 709.17M |
| Short-Term Investments | 26.51M | 26.52M | 36.92M | 5.01M | 10.04M | 19.82M | 0 | 0 | 0 | 0 |
| Accounts Receivable | 0 | 0 | 0 | 10.54M | 5.99M | 6.72M | 10.79M | 53.51M | 65.49M | 126.48M |
| Days Sales Outstanding | - | - | - | 37.59 | 18.35 | 17.43 | 18.39 | 49.05 | 48.61 | 78.38 |
| Inventory | 0 | 0 | 56.01K | 1.96M | 4.65M | 7.87M | 6.8M | 15.64M | 19.54M | 37.17M |
| Days Inventory Outstanding | - | - | 1.03 | 48.39 | 99.63 | 131.26 | 72.22 | 109.88 | 103.6 | 155.47 |
| Other Current Assets | 36.44K | 58.28K | 272.17K | 516.66K | 883K | 327K | 0 | 489K | 1.03M | 21.22M |
| Total Non-Current Assets | 253.09K | 200.27K | 5.26M | 1.01M | 33.11M | 27.68M | 54.82M | 250.78M | 227.8M | 209.95M |
| Property, Plant & Equipment | 244.2K | 191.38K | 245.43K | 1M | 130K | 3.98M | 3.62M | 3.7M | 3.58M | 2.97M |
| Fixed Asset Turnover | - | - | 2.04x | 101.93x | 915.95x | 35.42x | 59.22x | 107.54x | 137.20x | 198.18x |
| Goodwill | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Intangible Assets | 0 | 0 | 0 | 0 | 0 | 0 | 32.47M | 194.05M | 156.67M | 131.67M |
| Long-Term Investments | 0 | 0 | 5.01M | 0 | 0 | 0 | 0 | 16.49M | 21.56M | 22.54M |
| Other Non-Current Assets | 8.89K | 8.89K | 8.89K | 8.89K | 9K | 9K | 0 | 0 | 0 | 0 |
| Total Assets | 41.71M | 85.39M | 60.45M | 112.38M | 192.35M | 237.79M | 375.63M | 470.11M | 851.41M | 1.1B |
| Asset Turnover | - | - | 0.01x | 0.91x | 0.62x | 0.59x | 0.57x | 0.85x | 0.58x | 0.53x |
| Asset Growth % | -30.61% | 104.73% | -29.21% | 85.9% | 71.17% | 23.62% | 57.97% | 25.15% | 81.11% | 29.66% |
| Total Current Liabilities | 2.09M | 4.27M | 9.51M | 24.1M | 22.76M | 27.06M | 57.59M | 76.06M | 120.68M | 147.15M |
| Accounts Payable | 933.18K | 1.95M | 2.34M | 4.12M | 4.26M | 2.77M | 3.98M | 14.79M | 16.59M | 11.2M |
| Days Payables Outstanding | 7.85K | 15.54K | 42.83 | 101.83 | 91.17 | 46.17 | 42.19 | 103.92 | 87.97 | 46.86 |
| Short-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Deferred Revenue (Current) | 18.09K | 24.01K | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Current Liabilities | 897.12K | 1.5M | 2.04M | 3.24M | 4.1M | 4.28M | 5.37M | 51.29M | 11.16M | 135.95M |
| Current Ratio | 19.79x | 19.97x | 5.80x | 4.62x | 7.00x | 7.76x | 5.57x | 2.88x | 5.17x | 6.08x |
| Quick Ratio | 19.79x | 19.97x | 5.80x | 4.54x | 6.79x | 7.47x | 5.45x | 2.68x | 5.01x | 5.82x |
| Cash Conversion Cycle | - | - | - | -15.84 | 26.81 | 102.52 | 48.42 | 55.01 | 64.24 | 186.99 |
| Total Non-Current Liabilities | 303.39K | 157.46K | 154.8K | 647.53K | 0 | 3.89M | 17.62M | 6.17M | 3.1M | 2.56M |
| Long-Term Debt | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.35M |
| Capital Lease Obligations | 0 | 0 | 0 | 647.53K | 0 | 3.89M | 3.56M | 3.19M | 2.79M | 0 |
| Deferred Tax Liabilities | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Other Non-Current Liabilities | 303.39K | 157.46K | 154.8K | 0 | 0 | 0 | 14.06M | 2.98M | 315K | 209K |
| Total Liabilities | 2.4M | 4.42M | 9.67M | 24.75M | 22.76M | 30.96M | 75.21M | 82.23M | 123.78M | 149.71M |
| Total Debt | 0 | 0 | 0 | 948.05K | 29K | 4.2M | 3.89M | 3.56M | 3.19M | 2.35M |
| Net Debt | -13.89M | -57.5M | -16.56M | -88.56M | -130.21M | -167.24M | -294.5M | -134.08M | -514.37M | -706.82M |
| Debt / Equity | - | - | - | 0.01x | 0.00x | 0.02x | 0.01x | 0.01x | 0.00x | 0.00x |
| Debt / EBITDA | - | - | - | 0.03x | 0.00x | 0.08x | 0.04x | 0.03x | 0.01x | 0.01x |
| Net Debt / EBITDA | - | - | - | -2.78x | -3.15x | -3.18x | -2.86x | -1.12x | -2.21x | -2.39x |
| Interest Coverage | -59.95x | -41.13x | - | - | - | - | - | - | - | - |
| Total Equity | 39.31M | 80.96M | 50.78M | 87.63M | 169.6M | 206.83M | 300.42M | 387.88M | 727.63M | 954.27M |
| Equity Growth % | -29.14% | 105.97% | -37.28% | 72.55% | 93.54% | 21.95% | 45.25% | 29.11% | 87.59% | 31.15% |
| Book Value per Share | 0.47 | 0.94 | 0.49 | 0.83 | 1.60 | 1.92 | 2.70 | 3.41 | 5.82 | 7.50 |
| Total Shareholders' Equity | 39.31M | 80.96M | 50.78M | 87.63M | 169.6M | 206.83M | 300.42M | 387.88M | 727.63M | 954.27M |
| Common Stock | 82.97K | 102.55K | 102.74K | 103.4K | 104K | 103K | 105K | 107K | 121K | 123K |
| Retained Earnings | -108.15M | -126.56M | -160.56M | -128.69M | -53.7M | -26.31M | 49.86M | 121.27M | 285.16M | 474.19M |
| Treasury Stock | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Accumulated OCI | -113.48K | -159.17K | -20.25K | 9.51K | 31K | -148K | 24K | 14K | 64K | 0 |
| Minority Interest | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Dec 2016 | Dec 2017 | Dec 2018 | Dec 2019 | Dec 2020 | Dec 2021 | Dec 2022 | Dec 2023 | Dec 2024 | Dec 2025 | |
|---|---|---|---|---|---|---|---|---|---|---|
| Cash from Operations | -17.96M | -13.74M | -25.7M | 34.61M | 45.03M | 60.37M | 116.05M | 143.6M | 239.81M | 208.67M |
| Operating CF Margin % | - | - | -5140.88% | 33.83% | 37.82% | 42.87% | 54.18% | 36.06% | 48.77% | 35.43% |
| Operating CF Growth % | 0.29% | 23.5% | -87.04% | 234.65% | 30.12% | 34.06% | 92.22% | 23.74% | 67% | -12.98% |
| Net Income | -18.07M | -18.41M | -34M | 31.88M | 74.98M | 39.48M | 83.08M | 71.41M | 163.89M | 214.33M |
| Depreciation & Amortization | 43.41K | 45.69K | 37.98K | 297.73K | 885.32K | 192K | 1.24M | 32.88M | 37.77M | 37.87M |
| Stock-Based Compensation | 1.84M | 2.41M | 3.55M | 0 | 0 | 6.07M | 7.91M | 14.25M | 22.25M | 24.78M |
| Deferred Taxes | 0 | 0 | 0 | 0 | -32.97M | 9.32M | 4.94M | -17.82M | -9.39M | -6.85M |
| Other Non-Cash Items | -886.14K | 186.9K | 3.68M | 3.53M | 6.25M | 287K | 5.16M | 80.2M | -5.63M | -61.46M |
| Working Capital Changes | -884.4K | 2.03M | 4.71M | -1.1M | -4.11M | 5.02M | 13.73M | -37.32M | 30.91M | 0 |
| Change in Receivables | 0 | 0 | 0 | -10.54M | 4.55M | -632K | -3.82M | -43.08M | -11.96M | -61M |
| Change in Inventory | 0 | 0 | -56.01K | -1.9M | -2.69M | -3.22M | 1.06M | -4.74M | -3.9M | 464K |
| Change in Payables | -860.95K | 1.01M | 391.79K | 1.78M | 138.57K | -1.49M | 1.21M | 10.82M | 1.8M | -5.39M |
| Cash from Investing | 3.55M | -3.96K | -15.53M | 37.22M | -5.01M | -11.02M | 9.21M | -293.5M | -556K | -58K |
| Capital Expenditures | -96.06K | 0 | -92.02K | -19.37K | -11.4K | -1.02M | -29K | -231K | -556K | -58K |
| CapEx % of Revenue | - | - | 18.4% | 0.02% | 0.01% | 0.73% | 0.01% | 0.06% | 0.11% | 0.01% |
| Acquisitions | 23.46K | 0 | 0 | 0 | 0 | 0 | 10M | 0 | 0 | 0 |
| Investments | - | - | - | - | - | - | - | - | - | - |
| Other Investing | -23.46K | -3.96K | -14.99M | 0 | 0 | 0 | -10M | -279.81M | 0 | 0 |
| Cash from Financing | 68.99K | 57.35M | 293.12K | 1.12M | 701.93K | -8.14M | 1.69M | -10.86M | 140.66M | -16.99M |
| Debt Issued (Net) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Equity Issued (Net) | 0 | 1000K | 0 | 1000K | 758.13K | -1000K | -1000K | 0 | 1000K | 0 |
| Dividends Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Share Repurchases | -11.27K | 0 | -4.45K | 0 | 0 | -12.09M | -6.91M | 0 | -296K | -25.3M |
| Other Financing | 68.99K | 3.58M | 293.12K | 0 | -56.2K | 3.95M | 8.6M | -10.86M | -39K | -16.99M |
| Net Change in Cash | -14.34M | 43.6M | -40.94M | 72.95M | 40.73M | 41.21M | 126.95M | -160.76M | 379.92M | 191.62M |
| Free Cash Flow | -18.06M | -13.74M | -25.8M | 34.59M | 45.02M | 59.35M | 116.02M | 61.86M | 239.25M | 208.61M |
| FCF Margin % | - | - | -5159.28% | 33.81% | 37.81% | 42.14% | 54.16% | 15.53% | 48.65% | 35.42% |
| FCF Growth % | -0.12% | 23.9% | -87.71% | 234.1% | 30.16% | 31.82% | 95.48% | -46.68% | 286.79% | -12.81% |
| FCF per Share | -0.22 | -0.16 | -0.25 | 0.33 | 0.42 | 0.55 | 1.04 | 0.54 | 1.91 | 1.64 |
| FCF Conversion (FCF/Net Income) | 0.99x | 0.75x | 0.76x | 1.09x | 0.60x | 1.53x | 1.40x | 2.01x | 1.46x | 0.97x |
| Interest Paid | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 705K | 1.4M | 0 |
| Taxes Paid | 0 | 0 | 0 | 0 | 0 | 3M | 7.67M | 50.46M | 68.45M | 0 |
| Metric | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2023 | 2024 | 2025 |
|---|---|---|---|---|---|---|---|---|---|---|
| Return on Equity (ROE) | -38.13% | -30.62% | -51.62% | 46.06% | 58.3% | 20.98% | 32.76% | 20.75% | 29.38% | 25.49% |
| Return on Invested Capital (ROIC) | -54.92% | -57.32% | -91.77% | 143.39% | 161.1% | 99.49% | 335.67% | 50.14% | 62.66% | 83.93% |
| Gross Margin | - | - | -3883.84% | 85.57% | 85.69% | 84.46% | 83.94% | 86.95% | 86% | 85.19% |
| Net Margin | - | - | -6800.7% | 31.16% | 62.97% | 28.03% | 38.79% | 17.93% | 33.33% | 36.39% |
| Debt / Equity | - | - | - | 0.01x | 0.00x | 0.02x | 0.01x | 0.01x | 0.00x | 0.00x |
| Interest Coverage | -59.95x | -41.13x | - | - | - | - | - | - | - | - |
| FCF Conversion | 0.99x | 0.75x | 0.76x | 1.09x | 0.60x | 1.53x | 1.40x | 2.01x | 1.46x | 0.97x |
| Revenue Growth | - | - | - | 20361.2% | 16.39% | 18.27% | 52.1% | 85.9% | 23.49% | 19.78% |
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