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GLUE logoMonte Rosa Therapeutics, Inc.(GLUE)Earnings, Financials & Key Ratios

GLUE•NASDAQ
Price updated Jun 11, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutMonte Rosa Therapeutics, Inc., a biopharmaceutical company, engages in the development of novel small molecule precision medicines that employ the body's natural mechanisms to selectively degrade therapeutically relevant proteins. It develops an oral molecular glue degrader for GSPT1, a translational termination factor and degron-containing protein for the treatment of Myc-driven cancers. The company also develops CDK2 to treat ovarian, uterine, and breast cancers; NEK7 for the treatment of inflammatory diseases, such as Crohn's disease, neurodegenerative disease, diabetes, and liver disease; VAV1, a target protein for autoimmune diseases; and BCL11A, a therapeutically-relevant protein in hemoglobinopathies. Monte Rosa Therapeutics, Inc. was incorporated in 2019 and is headquartered in Boston, Massachusetts.Show more
  • Revenue$124M+63.5%
  • EBITDA-$46M+37.2%
  • Net Income-$39M+46.9%
  • EPS (Diluted)-0.46+53.1%
  • Gross Margin93.24%+4.5%
  • EBITDA Margin-37.08%+61.6%
  • Operating Margin-43.83%+59.1%
  • Net Margin-31.23%+67.5%
  • ROE-16.94%+53.1%
  • ROIC-44.25%+49.6%
  • Debt/Equity0.17-12.2%

GLUE Key Insights

Monte Rosa Therapeutics, Inc. (GLUE) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

No significant strengths identified

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Shares diluted 12.4% in last year
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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GLUE Price & Volume

Monte Rosa Therapeutics, Inc. (GLUE) stock price & volume — 10-year historical chart

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GLUE Growth Metrics

Monte Rosa Therapeutics, Inc. (GLUE) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-
3 Years-
TTM-73.07%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM-2213.02%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM-2757.14%

Return on Capital

10 Years-70.74%
5 Years-33.89%
3 Years-32.1%
Last Year-16.27%

GLUE Recent Earnings

Monte Rosa Therapeutics, Inc. (GLUE) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 8/12 qtrs (67%)●Beat Revenue 5/12 qtrs (56%)
Q2 2026Latest
May 7, 2026
EPS
$0.45
Est $0.28
-60.7%
Revenue
$4M
Est $11M
-61.7%
Q2 2026
Mar 17, 2026
EPS
$0.54
Est $0.35
-53.6%
Revenue
$3M
Est $16M
-82.0%
Q4 2025
Nov 6, 2025
EPS
$0.33
Est $0.37
+9.9%
Revenue
$13M
Est $16M
-17.7%
Q3 2025
Aug 7, 2025
EPS
$0.15
Est $0.38
+60.2%
Revenue
$23M
Est $8M
+198.4%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMay 7, 2026
$0.45vs $0.28-60.7%
$4Mvs $11M-61.7%
Q2 2026Mar 17, 2026
$0.54vs $0.35-53.6%
$3Mvs $16M-82.0%
Q4 2025Nov 6, 2025
$0.33vs $0.37+9.9%
$13Mvs $16M-17.7%
Q3 2025Aug 7, 2025
$0.15vs $0.38+60.2%
$23Mvs $8M+198.4%
Based on last 12 quarters of dataView full earnings history →

GLUE Peer Comparison

Monte Rosa Therapeutics, Inc. (GLUE) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
ARVN logoARVNArvinas, Inc.Direct Competitor457.46M7.09-5.54-0.3%-247.54%-44.39%0.02
KYMR logoKYMRKymera Therapeutics, Inc.Direct Competitor6.77B82.96-22.48-16.72%-6.12%-25.02%0.05
PRAX logoPRAXPraxis Precision Medicines, Inc.Direct Competitor7.16B247.98-18.40-100%-43.02%0.00
VRTX logoVRTXVertex Pharmaceuticals IncorporatedProduct Competitor113.2B445.0429.059.57%35.4%23.93%0.21
BEAM logoBEAMBeam Therapeutics Inc.Product Competitor3.02B29.41-36.31120.01%-49.17%-5.89%0.24
IMVT logoIMVTImmunovant, Inc.Product Competitor6.75B32.88-11.87-68.16%0.00
PTGX logoPTGXProtagonist Therapeutics, Inc.Product Competitor7.06B109.79-53.56-89.41%-6.48%-17.76%0.02
CRL logoCRLCharles River Laboratories International, Inc.Supply Chain9.06B188.06-64.63-0.85%-4.59%-5.66%0.95

Compare GLUE vs Peers

Monte Rosa Therapeutics, Inc. (GLUE) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs ARVN

Most directly comparable listed peer for GLUE.

Scale Benchmark

vs VRTX

Larger-name benchmark to compare GLUE against a more recognizable public peer.

Peer Set

Compare Top 5

vs ARVN, KYMR, PRAX, VRTX

GLUE Income Statement

Monte Rosa Therapeutics, Inc. (GLUE) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Sales/Revenue
0000075.62M123.67M42.95M
Revenue Growth %
------63.54%-73.07%
Cost of Goods Sold
72K537K006.22M8.12M8.36M2.03M
COGS % of Revenue
-----10.74%6.76%-
Gross Profit
-72K▲ 0%
-537K▼ 645.8%
0▲ 100.0%
0▲ 0%
-6.22M▲ 0%
67.5M▲ 1184.9%
115.32M▲ 70.8%
40.92M▲ 0%
Gross Margin %
-----89.26%93.24%95.28%
Gross Profit Growth %
--645.83%100%--1184.88%70.84%-
Operating Expenses
7.99M27.47M72.88M112.38M137.09M148.61M169.52M189.2M
OpEx % of Revenue
-----196.52%137.08%-
Selling, General & Admin
644K4M15.73M27.32M32.04M35.17M36.38M37.85M
SG&A % of Revenue
-----46.51%29.42%-
Research & Development
7.35M23.47M57.16M85.06M105.05M121.56M141.5M153.38M
R&D % of Revenue
-----160.75%114.42%-
Other Operating Expenses
00000-8.12M-8.36M-1000K
Operating Income
-7.99M▲ 0%
-28.01M▼ 250.4%
-72.88M▼ 160.2%
-112.38M▼ 54.2%
-143.31M▼ 27.5%
-81.11M▲ 43.4%
-54.21M▲ 33.2%
-148.28M▲ 0%
Operating Margin %
------107.26%-43.83%-345.21%
Operating Income Growth %
--250.39%-160.2%-54.2%-27.52%43.4%33.17%-
EBITDA
-7.92M-27.47M-70.75M-108.64M-137.09M-72.99M-45.85M-139.94M
EBITDA Margin %
------96.52%-37.08%-325.8%
EBITDA Growth %
--246.79%-157.53%-53.55%-26.19%46.76%37.18%-2378.06%
D&A (Non-Cash Add-back)
72K537K2.13M3.75M6.22M8.12M8.36M8.34M
EBIT
-7.74M-28.01M-72.88M-112.38M-143.31M-81.11M-54.21M-148.28M
Net Interest Income
-9889K46K09.33M10.57M12.94M15.09M
Interest Income
129K46K3.76M9.33M10.57M12.94M15.09M
Interest Expense
1K003.76M0000
Other Income/Expense
254K-7.87M-1.08M3.88M8.3M10.98M14.48M16.4M
Pretax Income
-7.74M▲ 0%
-35.88M▼ 363.6%
-73.96M▼ 106.1%
-108.5M▼ 46.7%
-135.01M▼ 24.4%
-70.13M▲ 48.1%
-39.72M▲ 43.4%
-131.88M▲ 0%
Pretax Margin %
------92.74%-32.12%-307.04%
Income Tax
0000338K2.57M-1.1M-1.87M
Effective Tax Rate %
0%0%0%0%-0.25%-3.66%2.76%1.42%
Net Income
-8.02M▲ 0%
-35.88M▼ 347.5%
-73.96M▼ 106.1%
-108.5M▼ 46.7%
-135.35M▼ 24.7%
-72.7M▲ 46.3%
-38.63M▲ 46.9%
-130.01M▲ 0%
Net Margin %
------96.14%-31.23%-302.69%
Net Income Growth %
--347.54%-106.13%-46.71%-24.75%46.29%46.87%-2213.02%
Net Income (Continuing)
-7.74M-35.88M-73.96M-108.5M-135.35M-72.7M-38.63M-130.01M
Discontinued Operations
00000000
Minority Interest
00000000
EPS (Diluted)
-0.18▲ 0%
-0.82▼ 355.6%
-1.59▼ 93.9%
-2.30▼ 44.7%
-2.63▼ 14.3%
-0.98▲ 62.7%
-0.46▲ 53.1%
-1.98▲ 0%
EPS Growth %
--355.56%-93.9%-44.65%-14.35%62.74%53.06%-2757.14%
EPS (Basic)
-0.18-0.82-1.59-2.30-2.63-0.98-0.46-
Diluted Shares Outstanding
44M44M46.54M47.23M51.4M73.91M83.07M65.54M
Basic Shares Outstanding
44M44M46.54M47.23M51.4M73.91M83.07M65.54M
Dividend Payout Ratio
--------

GLUE Balance Sheet

Monte Rosa Therapeutics, Inc. (GLUE) balance sheet — assets, liabilities & shareholders' equity

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Total Current Assets
9.76M43.59M348.67M275.89M236.21M377.44M393.19M677.55M
Cash & Short-Term Investments
6M41.7M346.07M262.83M232.41M372.15M377.1M666.22M
Cash Only
6M41.7M346.07M54.91M128.1M224.25M129.88M159.86M
Short-Term Investments
000207.91M104.31M147.9M247.22M506.36M
Accounts Receivable
0007.66M505K173K4.6M4.61M
Days Sales Outstanding
-----0.8313.5835.15
Inventory
00000000
Days Inventory Outstanding
--------
Other Current Assets
3.25M100K05.4M3.29M5.12M11.48M6.72M
Total Non-Current Assets
1.33M5.79M17.66M66.5M67.54M61.29M55.47M58.88M
Property, Plant & Equipment
1.33M4.62M12.32M61.91M62.61M56.31M50.37M53.1M
Fixed Asset Turnover
-----1.34x2.46x0.81x
Goodwill
00000000
Intangible Assets
00000000
Long-Term Investments
01.16M5.34M00004.95M
Other Non-Current Assets
0004.6M4.93M4.98M5.1M5.78M
Total Assets
11.09M▲ 0%
49.38M▲ 345.1%
366.33M▲ 641.9%
342.39M▼ 6.5%
303.75M▼ 11.3%
438.73M▲ 44.4%
448.66M▲ 2.3%
736.43M▲ 0%
Asset Turnover
-----0.17x0.28x0.09x
Asset Growth %
-345.09%641.89%-6.54%-11.28%44.44%2.26%139.99%
Total Current Liabilities
4.29M29.27M16.64M25.57M46.59M156.95M64.21M71.04M
Accounts Payable
3.19M7.07M6.56M7.86M11.15M17.21M3.55M7.9M
Days Payables Outstanding
16.2K4.8K--654.21773.73155.071.42K
Short-Term Debt
750K000004.4M4.48M
Deferred Revenue (Current)
000017.68M117.23M29.57M105.83M
Other Current Liabilities
021.08M840K10.64M9.26M11.57M26.69M25.59M
Current Ratio
2.27x1.49x20.96x10.79x5.07x2.40x6.12x9.54x
Quick Ratio
2.27x1.49x20.96x10.79x5.07x2.40x6.12x9.54x
Cash Conversion Cycle
--------1.38K
Total Non-Current Liabilities
18.95M68.83M2.18M45.41M77.91M58.85M151.39M143.48M
Long-Term Debt
067.76M000034.79M34.58M
Capital Lease Obligations
00043.87M42.88M39M037.04M
Deferred Tax Liabilities
00000000
Other Non-Current Liabilities
18.95M02.18M1.53M2.71M3.7M5.26M108.89M
Total Liabilities
23.24M98.11M18.81M70.98M124.5M215.8M215.6M214.51M
Total Debt
750K67.76M047M46.04M42.72M39.19M39.06M
Net Debt
-5.25M26.07M-346.07M-7.91M-82.06M-181.54M-90.69M-120.8M
Debt / Equity
---0.17x0.26x0.19x0.17x0.07x
Debt / EBITDA
--------0.28x
Net Debt / EBITDA
-------0.86x
Interest Coverage
-7739.00x---29.86x----
Total Equity
-12.15M▲ 0%
-48.73M▼ 301.1%
347.51M▲ 813.2%
271.41M▼ 21.9%
179.25M▼ 34.0%
222.94M▲ 24.4%
233.06M▲ 4.5%
521.92M▲ 0%
Equity Growth %
--301.12%813.17%-21.9%-33.96%24.37%4.54%133.19%
Book Value per Share
-0.28-1.117.475.753.493.022.817.96
Total Shareholders' Equity
-12.15M-48.73M347.51M271.41M179.25M222.94M233.06M521.92M
Common Stock
50K1K5K5K5K6K7K8K
Retained Earnings
-12.2M-48.08M-122.03M-230.54M-365.89M-438.59M-477.21M-521.72M
Treasury Stock
00000000
Accumulated OCI
0-1.06M-2.02M-1.75M-2.72M-3.36M-3.83M-4.75M
Minority Interest
00000000

GLUE Cash Flow Statement

Monte Rosa Therapeutics, Inc. (GLUE) cash flow — operating, investing & free cash flow history

MetricDec'19Dec'20Dec'21Dec'22Dec'23Dec'24Dec'25TTM
Cash from Operations
-6.17M-23.05M-59.36M-92.47M-43.8M42M-22.8M-14.68M
Operating CF Margin %
-----55.53%-18.43%-
Operating CF Growth %
--273.45%-157.51%-55.76%52.63%195.88%-154.29%437.82%
Net Income
-7.74M-35.88M-73.96M-108.5M-135.35M-72.7M-38.63M-130.01M
Depreciation & Amortization
72K537K2.13M3.75M6.22M8.12M8.36M8.97M
Stock-Based Compensation
0354K5.2M11.66M16.67M18.13M18.86M13.57M
Deferred Taxes
0017K00000
Other Non-Cash Items
-276K7.68M960K2.76M-3.81M-2.95M-2.2M122.31M
Working Capital Changes
1.77M4.25M6.29M-2.13M72.47M91.4M-9.19M-29.51M
Change in Receivables
000-1871.9M332K-7M-970K
Change in Inventory
0001870000
Change in Payables
2.86M3.44M-706K-744K5.76M6.25M-13.71M-7.34M
Cash from Investing
-1.39M-3.39M-9.65M-219.22M88.8M-44.45M-101.83M-262.6M
Capital Expenditures
-1.39M-3.39M-9.73M-12.91M-19.04M-3.99M-4.7M-4.98M
CapEx % of Revenue
-----5.27%3.8%11.6%
Acquisitions
0079K109K62K000
Investments
--------
Other Investing
000000038.79M
Cash from Financing
15M60.06M377.56M20.47M27.49M98.89M30.35M358.67M
Debt Issued (Net)
750K0000000
Equity Issued (Net)
14.25M60.06M380.75M20.05M27.49M303K30.35M358.32M
Dividends Paid
00000000
Share Repurchases
00000-641K00
Other Financing
00-3.19M411K098.59M0348K
Net Change in Cash
7.44M▲ 0%
32.45M▲ 336.1%
308.55M▲ 850.7%
-291.22M▼ 194.4%
72.49M▲ 124.9%
96.44M▲ 33.0%
-94.28M▼ 197.8%
81.4M▲ 0%
Free Cash Flow
-7.56M▲ 0%
-26.44M▼ 249.9%
-69.09M▼ 161.3%
-105.38M▼ 52.5%
-62.84M▲ 40.4%
38.01M▲ 160.5%
-27.5M▼ 172.3%
-19.66M▲ 0%
FCF Margin %
-----50.26%-22.23%-45.76%
FCF Growth %
--249.85%-161.31%-52.51%40.36%160.48%-172.35%-164.49%
FCF per Share
-0.17-0.60-1.48-2.23-1.220.51-0.33-0.30
FCF Conversion (FCF/Net Income)
0.77x0.64x0.80x0.85x0.32x-0.58x0.59x0.15x
Interest Paid
00000000
Taxes Paid
00000000

GLUE Key Ratios

Monte Rosa Therapeutics, Inc. (GLUE) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric202020212022202320242025TTM
Return on Equity (ROE)--49.51%-35.06%-60.07%-36.15%-16.94%-40.99%
Return on Invested Capital (ROIC)---63.63%-59.6%-87.79%-44.25%-51.67%
Gross Margin----89.26%93.24%95.28%
Net Margin-----96.14%-31.23%-302.69%
Debt / Equity--0.17x0.26x0.19x0.17x0.07x
Interest Coverage---29.86x----
FCF Conversion0.64x0.80x0.85x0.32x-0.58x0.59x0.15x
Revenue Growth-----63.54%-73.07%
Related:GLUE Dividend History·GLUE Revenue History·GLUE Price History·GLUE P/E History·GLUE Financial Ratios·GLUE Institutional Holders

GLUE SEC Filings & Documents

Monte Rosa Therapeutics, Inc. (GLUE) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

May 7, 2026·SEC

Material company update

Mar 17, 2026·SEC

Material company update

Feb 10, 2026·SEC

10-K Annual Reports

3
FY 2026

Mar 17, 2026·SEC

FY 2025

Mar 20, 2025·SEC

FY 2024

Mar 14, 2024·SEC

10-Q Quarterly Reports

6
FY 2026

May 7, 2026·SEC

FY 2025

Nov 6, 2025·SEC

FY 2025

Aug 7, 2025·SEC

GLUE Frequently Asked Questions

Monte Rosa Therapeutics, Inc. (GLUE) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Monte Rosa Therapeutics, Inc. (GLUE) reported $43.0M in revenue for fiscal year 2025.

Monte Rosa Therapeutics, Inc. (GLUE) grew revenue by 63.5% over the past year. This is strong growth.

Monte Rosa Therapeutics, Inc. (GLUE) reported a net loss of $130.0M for fiscal year 2025.

Dividend & Returns

Monte Rosa Therapeutics, Inc. (GLUE) has a return on equity (ROE) of -16.9%. Negative ROE indicates the company is unprofitable.

Monte Rosa Therapeutics, Inc. (GLUE) had negative free cash flow of $19.7M in fiscal year 2025, likely due to heavy capital investments.

What if you invested $1,000 in GLUE back in 2019?

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