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Exelixis, Inc. (EXEL) 10-Year Financial Performance & Capital Metrics

EXEL •
HealthcareBiotechnologyOncology Therapeutics Developers
AboutExelixis, Inc., an oncology-focused biotechnology company, focuses on the discovery, development, and commercialization of new medicines to treat cancers in the United States. The company's products include CABOMETYX tablets for the treatment of patients with advanced renal cell carcinoma who received prior anti-angiogenic therapy; and COMETRIQ capsules for the treatment of patients with progressive and metastatic medullary thyroid cancer. Its CABOMETYX and COMETRIQ are derived from cabozantinib, an inhibitor of multiple tyrosine kinases, including MET, AXL, RET, and VEGF receptors. The company also offers COTELLIC, an inhibitor of MEK as a combination regimen to treat advanced melanoma; and MINNEBRO, an oral non-steroidal selective blocker of the mineralocorticoid receptor for the treatment of hypertension in Japan. In addition, it is developing XL092, an oral tyrosine kinase inhibitor that targets VEGF receptors, MET, AXL, MER, and other kinases implicated in growth and spread of cancer; XB002, an antibody-drug conjugate composed of human mAb against tissue factor (TF) for the treatment of advanced solid tumors; XL102, an orally bioavailable cyclin-dependent kinase 7 (CDK7) inhibitor for the treatment of advanced or metastatic solid tumors; and XB002 for the treatment of non-hodgkin's lymphoma. Exelixis, Inc. has research collaborations and license agreements with Ipsen Pharma SAS; Takeda Pharmaceutical Company Ltd.; F. Hoffmann-La Roche Ltd.; Redwood Bioscience, Inc.; R.P. Scherer Technologies, LLC; Catalent Pharma Solutions, Inc.; NBE Therapeutics AG; Aurigene Discovery Technologies Limited; Iconic Therapeutics, Inc.; Invenra, Inc.; StemSynergy Therapeutics, Inc.; Genentech, Inc.; Bristol-Myers Squibb Company; and Daiichi Sankyo Company, Limited. The company was formerly known as Exelixis Pharmaceuticals, Inc. and changed its name to Exelixis, Inc. in February 2000. Exelixis, Inc. was incorporated in 1994 and is headquartered in Alameda, California.Show more
  • Revenue $2.32B +7.0%
  • EBITDA $872M +37.7%
  • Net Income $783M +50.1%
  • EPS (Diluted) 2.78 +58.0%
  • Gross Margin -
  • EBITDA Margin 37.59% +28.7%
  • Operating Margin 37.59% +34.8%
  • Net Margin 33.73% +40.3%
  • ROE 35.53% +53.6%
  • ROIC 32.15% +56.3%
  • Debt/Equity 0.08 -5.8%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓Excellent 3Y average ROE of 22.5%
  • ✓Strong 5Y profit CAGR of 47.6%
  • ✓Strong Piotroski F-Score: 7/9
  • ✓FCF machine: 38.1% free cash flow margin
  • ✓Strong 5Y sales CAGR of 18.6%

✗Weaknesses

No significant weaknesses identified

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y51.19%
5Y18.63%
3Y12.93%
TTM9.93%

Profit (Net Income) CAGR

10Y-
5Y47.58%
3Y62.53%
TTM45.18%

EPS CAGR

10Y-
5Y51.35%
3Y70.59%
TTM51.92%

ROCE

10Y Avg19.33%
5Y Avg17.37%
3Y Avg21.74%
Latest35.01%

Peer Comparison

Oncology Therapeutics Developers
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
EXELExelixis, Inc.11.81B44.0615.856.98%29.63%31.37%7.49%0.08
INCYIncyte Corporation20.1B101.2715.8021.22%25.03%24.9%6.74%0.01
GMABGenmab A/S18.13B29.4415.3630.67%46.8%114.25%6.6%0.03
SNDXSyndax Pharmaceuticals, Inc.1.89B21.71-5.82-279.31%-269.93%1.20
RCUSArcus Biosciences, Inc.2.55B20.37-6.19-4.26%-142.91%-55.94%0.16
RLAYRelay Therapeutics, Inc.1.78B10.26-6.3753.44%-18.01%-48.76%0.06
STROSutro Biopharma, Inc.1.74B20.47-6.92-59.64%-205.18%-234.19%4.57
OLMAOlema Pharmaceuticals, Inc.1.66B24.20-11-48.77%0.00

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Profit & Loss

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Jan 2025Jan 2026
Sales/Revenue+191.45M452.48M853.83M967.77M987.54M1.43B1.61B1.83B2.17B2.32B
Revenue Growth %415.05%136.34%88.7%13.35%2.04%45.31%12.27%13.6%18.49%6.98%
Cost of Goods Sold+6.55M15.07M26.35M33.1M36.27M52.87M57.91M72.55M76.22M0
COGS % of Revenue3.42%3.33%3.09%3.42%3.67%3.68%3.59%3.96%3.51%-
Gross Profit+184.9M437.41M827.48M934.68M951.27M1.38B1.55B1.76B2.09B0
Gross Margin %96.58%96.67%96.91%96.58%96.33%96.32%96.41%96.04%96.49%-
Gross Profit Growth %455.64%136.56%89.18%12.96%1.77%45.29%12.38%13.17%19.05%-100%
Operating Expenses+212.11M271.53M388.62M565.21M841.21M1.1B1.35B1.59B1.49B1.45B
OpEx % of Revenue110.79%60.01%45.52%58.4%85.18%76.34%83.9%86.7%68.61%62.41%
Selling, General & Admin116.14M159.33M206.37M228.24M293.36M401.71M459.86M542.71M492.13M518.73M
SG&A % of Revenue60.66%35.21%24.17%23.58%29.71%27.99%28.54%29.65%22.69%22.36%
Research & Development95.97M112.17M182.26M336.96M547.85M693.72M891.81M1.04B910.41M825M
R&D % of Revenue50.13%24.79%21.35%34.82%55.48%48.34%55.36%57.05%41.98%35.56%
Other Operating Expenses00397K680K912K-184K-197K085.33M104.21M
Operating Income+-28.12M165.91M438.86M369.47M110.06M286.67M201.48M170.88M604.62M872.19M
Operating Margin %-14.69%36.67%51.4%38.18%11.14%19.98%12.51%9.34%27.88%37.59%
Operating Income Growth %76.84%689.92%164.51%-15.81%-70.21%160.46%-29.71%-15.19%253.82%44.26%
EBITDA+-27.12M167.1M443.77M380.64M119.2M300.3M222.36M196.6M633.42M872.19M
EBITDA Margin %-14.17%36.93%51.97%39.33%12.07%20.93%13.8%10.74%29.21%37.59%
EBITDA Growth %77.4%716.09%165.58%-14.23%-68.68%151.92%-25.95%-11.58%222.18%37.7%
D&A (Non-Cash Add-back)1M1.19M4.92M11.17M9.14M13.63M20.88M25.72M28.8M0
EBIT-37.16M167.11M438.86M398.11M110.06M286.67M201.48M170.88M689.95M0
Net Interest Income+-30.48M-3.8M12.84M27.96M19.86M7.67M33.06M86.54M77.16M0
Interest Income2.58M4.88M12.84M27.96M19.86M7.67M33.06M86.54M77.16M69.21M
Interest Expense33.06M8.68M00000000
Other Income/Expense-42.1M-7.33M13.24M28.64M20.78M7.49M32.87M86.64M77.02M69.02M
Pretax Income+-70.22M158.58M452.09M398.11M130.84M294.15M234.35M257.52M681.64M941.21M
Pretax Margin %-36.68%35.05%52.95%41.14%13.25%20.5%14.55%14.07%31.43%40.57%
Income Tax+04.35M-237.98M77.1M19.06M63.09M52.07M49.76M160.37M158.64M
Effective Tax Rate %100%97.26%152.64%80.63%85.44%78.55%77.78%80.68%76.47%83.15%
Net Income+-70.22M154.23M690.07M321.01M111.78M231.06M182.28M207.76M521.27M782.57M
Net Margin %-36.68%34.09%80.82%33.17%11.32%16.1%11.31%11.35%24.04%33.73%
Net Income Growth %58.63%319.63%347.44%-53.48%-65.18%106.71%-21.11%13.98%150.89%50.13%
Net Income (Continuing)-70.22M154.23M690.07M321.01M111.78M231.06M182.28M207.76M521.27M0
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-0.280.492.211.020.350.720.560.651.762.78
EPS Growth %65.43%275%351.02%-53.85%-65.69%105.71%-22.22%16.07%170.77%57.95%
EPS (Basic)-0.280.522.321.060.360.730.570.651.802.88
Diluted Shares Outstanding250.53M312M312.8M315.01M318M322.36M324.56M321.46M296.13M281.86M
Basic Shares Outstanding250.53M293.59M297.89M302.58M308.27M314.88M321.53M318.15M290.03M271.57M
Dividend Payout Ratio----------

Balance Sheet

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Jan 2025Jan 2026
Total Current Assets+470.8M484.87M897.02M1.01B1.45B1.83B1.62B1.32B1.47B1.44B
Cash & Short-Term Investments419.8M387.77M693.33M852.24M1.21B1.47B1.31B995.3M1.11B1.06B
Cash Only151.69M183.16M314.77M266.5M319.22M647.17M501.19M262.99M217.37M482.49M
Short-Term Investments268.12M204.61M378.56M585.74M887.32M819.9M807.27M732.31M893.9M576.6M
Accounts Receivable40.44M81.19M162.77M119.07M160.88M282.65M214.78M237.41M265.44M286.92M
Days Sales Outstanding77.1165.569.5844.9159.4671.948.6647.3544.6745.14
Inventory3.34M6.66M9.84M12.89M20.97M27.49M33.3M17.32M22.39M21.69M
Days Inventory Outstanding185.95161.28136.29142.11211.05189.79209.8887.16107.22-
Other Current Assets0504K000062.21M67.93M68.48M75.6M
Total Non-Current Assets+126.74M170.42M525.27M874.48M691.94M781.49M1.45B1.62B1.48B1.4B
Property, Plant & Equipment2.07M25.74M56.76M90.73M67.38M104.03M345.44M470.85M359.11M441.26M
Fixed Asset Turnover92.45x17.58x15.04x10.67x14.66x13.79x4.66x3.89x6.04x5.26x
Goodwill63.68M63.68M63.68M63.68M63.68M63.68M63.68M63.68M63.68M63.68M
Intangible Assets0000000000
Long-Term Investments55.6M64.25M157.19M536.38M332.31M371.11M756.73M728.72M637.29M0
Other Non-Current Assets5.38M16.74M3.52M11.31M71.85M131M55.77M00603.6M
Total Assets+597.54M655.29M1.42B1.89B2.14B2.62B3.07B2.94B2.95B2.84B
Asset Turnover0.32x0.69x0.60x0.51x0.46x0.55x0.52x0.62x0.74x0.82x
Asset Growth %79.8%9.67%117.05%32.58%13.35%22.41%17.4%-4.2%0.18%-3.5%
Total Current Liabilities+270.59M115.17M105.47M142.75M204.66M337.59M324.36M394.28M403.77M405.64M
Accounts Payable6.57M9.57M10.9M11.58M23.63M24.26M32.67M33.77M38.19M29.62M
Days Payables Outstanding365.72231.97151.01127.72237.81167.46205.9169.89182.9-
Short-Term Debt189.12M000000000
Deferred Revenue (Current)19.66M31.98M15.9M6.6M1.79M7.81M7.49M000
Other Current Liabilities33.1M52.54M3.19M15.13M42.66M45.55M71.44M82.12M267.22M405.64M
Current Ratio1.74x4.21x8.50x7.08x7.06x5.43x4.99x3.34x3.63x3.56x
Quick Ratio1.73x4.15x8.41x6.99x6.96x5.35x4.89x3.30x3.58x3.50x
Cash Conversion Cycle-102.67-5.254.8659.332.794.2352.64-35.39-31.01-
Total Non-Current Liabilities+237.63M255.16M29.36M56.95M53.56M68.03M258.7M284.17M299.72M277.46M
Long-Term Debt000000000173.04M
Capital Lease Obligations014.53M12.18M48.01M49.09M51.27M190.17M189.94M190.82M0
Deferred Tax Liabilities0-14.53M00000000
Other Non-Current Liabilities541K16.64M1.29M2.35M721K8.02M61.95M94.22M108.89M104.42M
Total Liabilities508.22M370.33M134.83M199.7M258.22M405.62M583.06M678.45M703.49M683.1M
Total Debt+189.12M14.53M14.92M50.74M49.09M51.27M190.17M189.94M190.82M173.04M
Net Debt37.44M-168.63M-299.86M-215.76M-270.13M-595.9M-311.02M-73.05M-26.55M-309.45M
Debt / Equity2.12x0.05x0.01x0.03x0.03x0.02x0.08x0.08x0.09x0.08x
Debt / EBITDA-0.09x0.03x0.13x0.41x0.17x0.86x0.97x0.30x0.20x
Net Debt / EBITDA--1.01x-0.68x-0.57x-2.27x-1.98x-1.40x-0.37x-0.04x-0.35x
Interest Coverage-0.85x19.12x--------
Total Equity+89.32M284.96M1.29B1.69B1.88B2.21B2.49B2.26B2.24B2.16B
Equity Growth %185.63%219.04%351.8%30.95%11.46%17.64%12.57%-9.02%-0.87%-3.69%
Book Value per Share0.360.914.125.355.916.867.677.047.587.67
Total Shareholders' Equity89.32M284.96M1.29B1.69B1.88B2.21B2.49B2.26B2.24B2.16B
Common Stock290K296K300K305K312K319K324K303K282K262K
Retained Earnings-1.98B-1.83B-880.36M-559.35M-447.57M-216.51M-34.23M-173.35M-98.65M-76.83M
Treasury Stock0000000000
Accumulated OCI-416K-347K-701K3.07M4.48M-758K-14.52M-3.75M-1.35M3.48M
Minority Interest0000000000

Cash Flow

Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Jan 2025Jan 2026
Cash from Operations+206.3M165.61M415.72M526.96M208.98M400.8M362.61M333.32M699.97M884.27M
Operating CF Margin %107.75%36.6%48.69%54.45%21.16%27.93%22.51%18.21%32.28%38.11%
Operating CF Growth %245.7%-19.72%151.02%26.76%-60.34%91.79%-9.53%-8.08%110%26.33%
Net Income-70.22M154.23M690.07M321.01M111.78M231.06M182.28M207.76M521.27M782.57M
Depreciation & Amortization1M1.19M7.77M8.35M9.14M13.63M20.88M25.72M28.8M29.05M
Stock-Based Compensation22.91M23.94M44.32M56.6M105.07M119.82M107.57M106.34M93.84M112.98M
Deferred Taxes11.41M3.26M-244.11M71M15.27M46.53M-60.36M-133.21M-59.46M126.24M
Other Non-Cash Items13.93M-10.05M-2.57M2.91M7.87M28.77M125.04M140.68M128.98M-166.58M
Working Capital Changes227.27M-6.95M-79.76M67.08M-40.14M-39.01M-12.8M-13.97M-13.45M0
Change in Receivables-37M-40.84M-85.47M43.72M-42.47M-122.32M66.85M-22.62M-27.95M-21.4M
Change in Inventory-722K-3.32M-3.18M-5.73M-21.9M-13.21M-11.68M-12.98M5.45M12.22M
Change in Payables164K3.01M856K39.69M50.51M55.09M23.36M53.25M-21.89M-50.15M
Cash from Investing+-216.05M35.8M-297.85M-587.25M-131.22M-42.88M-524.41M-26.95M-116.78M350.44M
Capital Expenditures-1.7M-21.14M-33.3M-12.83M-30.34M-54.23M-27.71M-40.47M-28.43M0
CapEx % of Revenue0.89%4.67%3.9%1.33%3.07%3.78%1.72%2.21%1.31%-
Acquisitions2.49M164K308K0000000
Investments----------
Other Investing-1.4M-1M308K00-10M-110.75M-122.5M-37.75M-61.75M
Cash from Financing+19.8M-169.93M9.69M12.55M-25.13M-14.8M586K-546.05M-628.81M-969.59M
Debt Issued (Net)-7.71M-185.79M-13K0000000
Equity Issued (Net)0000000-1000K-1000K0
Dividends Paid0000000000
Share Repurchases-4.11M-6.56M-7.57M0000-550.38M-652.03M-947.51M
Other Financing23.41M15.86M9.7M12.55M-25.13M-14.8M586K4.33M23.23M-969.59M
Net Change in Cash10.05M31.48M127.56M-47.74M52.63M343.12M-161.21M-239.68M-45.62M265.11M
Free Cash Flow+204.59M144.47M382.42M514.12M178.64M336.58M224.16M170.35M633.79M884.27M
FCF Margin %106.86%31.93%44.79%53.12%18.09%23.46%13.91%9.31%29.22%38.11%
FCF Growth %244.05%-29.39%164.71%34.44%-65.25%88.42%-33.4%-24%272.04%39.52%
FCF per Share0.820.461.221.630.561.040.690.532.143.14
FCF Conversion (FCF/Net Income)-2.94x1.07x0.60x1.64x1.87x1.73x1.99x1.60x1.34x1.13x
Interest Paid21.04M20.46M00000000
Taxes Paid190K538K10.68M7.87M4.12M12.96M127.87M185.66M170.48M0

Key Ratios

Metric2016201720182019202020212022202320242025
Return on Equity (ROE)-78.62%82.41%87.77%21.59%6.27%11.3%7.76%8.74%23.13%35.53%
Return on Invested Capital (ROIC)-16.09%102.38%59.63%22.55%5.36%13.34%7.97%5.87%20.57%32.15%
Gross Margin96.58%96.67%96.91%96.58%96.33%96.32%96.41%96.04%96.49%-
Net Margin-36.68%34.09%80.82%33.17%11.32%16.1%11.31%11.35%24.04%33.73%
Debt / Equity2.12x0.05x0.01x0.03x0.03x0.02x0.08x0.08x0.09x0.08x
Interest Coverage-0.85x19.12x--------
FCF Conversion-2.94x1.07x0.60x1.64x1.87x1.73x1.99x1.60x1.34x1.13x
Revenue Growth415.05%136.34%88.7%13.35%2.04%45.31%12.27%13.6%18.49%6.98%

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