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MIST logoMilestone Pharmaceuticals Inc. (MIST) Earnings History

Annual and quarterly earnings data from 2017 to 2025

TTM Net Income
-$79M
Net Loss
TTM EPS
$-0.95
Diluted
YoY EPS Growth
-11.9%
Declining
Net Margin
N/A
Profitability
Operating Margin-4019.4%
Gross MarginN/A
ROEN/A
ROAN/A
Highest Annual Net Income$0 (2025)
Highest Quarterly EPS$0.43 (Q4 2022)
Consecutive Profitable Years0 years
Q4 2025
Net Income-$34M
EPS$-0.15
QoQ Growth-182.9%Declining

Loading earnings history...

MIST EPS Growth (CAGR)

Compound annual growth rate of diluted earnings per share

1-Year
N/A
N/M
3-Year
N/A
N/M
5-Year
N/A
N/M
10-Year
N/A
N/M

CAGR (Compound Annual Growth Rate) shows the annualized growth rate of EPS over the specified period. A higher CAGR indicates stronger earnings momentum.

MIST Profitability Analysis

Margin trends over time

View revenue breakdown →
YearGross MarginOperating MarginNet Margin
20250.0%-4019.4%0.0%
2024---
2023100.0%-6109.8%-5968.5%
2022100.0%-1192.8%-1167.8%
2021100.0%-287.2%-285.7%
Gross Margin = Gross Profit ÷ Revenue
Operating Margin = Operating Income ÷ Revenue
Net Margin = Net Income ÷ Revenue

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Milestone Pharmaceuticals Inc. (MIST) Earnings Overview

As of May 8, 2026, Milestone Pharmaceuticals Inc. (MIST) reported trailing twelve-month net income of -$79M, reflecting -11.9% year-over-year growth. The company earned $-0.95 per diluted share over the past four quarters.

Looking at the long-term picture, MIST's historical earnings data spans multiple years. The company achieved its highest annual net income of $0 in fiscal 2025, representing a new all-time high.

Milestone Pharmaceuticals Inc. is currently reporting a net loss, though operating performance should be evaluated in the context of growth investments and industry dynamics View revenue history →

Compared to peers including ACAD ($376M net income, 36.5% margin), PRAX (-$327M net income), XENE (-$383M net income, -4612.1% margin), MIST has comparable earnings metrics. Compare MIST vs ACAD →

MIST Earnings vs Peers

Earnings metrics vs comparable public companies

CompanyTTM Net IncomeTTM EPSNet MarginROEYoY GrowthCompare
MIST logoMISTCurrent
-$79M$-0.95---11.9%—
ACAD logoACAD
$376M$2.1836.5%39.9%+68.4%
PRAX logoPRAX
-$327M$-11.31--45.8%-32.0%
XENE logoXENE
-$383M$-4.39-4612.1%-51.8%-44.9%
INVA logoINVA
$504M$5.9463.8%29.1%+816.7%
IDYA logoIDYA
-$140M$-1.58-52.0%-10.9%+61.9%
Best in group
Lowest in group

MIST Historical Earnings Data (2017–2025)

9 years
Fiscal Year Net Income YoY % Operating Income EPS (Diluted) Net Margin Op. Margin
2025$0+100.0%-$62M$-0.750.0%-4019.4%
2024-$42M+30.4%-$42M$-0.67--
2023-$60M-2.2%-$61M$-1.39-5968.5%-6109.8%
2022-$58M-36.3%-$60M$-1.35-1167.8%-1192.8%
2021-$43M+14.2%-$43M$-1.02-285.7%-287.2%
2020-$50M+9.5%-$51M$-1.70--
2019-$55M-138.2%-$58M$-3.50--
2018-$23M-186.7%-$24M$-0.98--
2017-$8M--$8M$-0.34--

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Compare MIST vs DBVT

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MIST — Frequently Asked Questions

Quick answers to the most common questions about buying MIST stock.

Is MIST growing earnings?

MIST EPS fell to $-0.95, with earnings declining -11.9%. This contrasts with the 5-year CAGR of N/A. TTM net income dropped to $-79M.

What are MIST's profit margins?

Milestone Pharmaceuticals Inc. net margin is N/A, with operating margin at -4019.4%. Below-average margins reflect competitive or cost pressures.

How consistent are MIST's earnings?

MIST earnings data spans 2017-2025. The declining earnings trend is -11.9% YoY. Historical data enables comparison across business cycles.

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MIST Earnings Over Time (2017–2025)

Net income and EPS trends