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MRSNMersana Therapeutics, Inc.
$29.08$145M
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MRSN logoMersana Therapeutics, Inc.(MRSN)Earnings, Financials & Key Ratios

MRSN•NASDAQ
Price updated Apr 24, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutMersana Therapeutics, Inc., a clinical stage biopharmaceutical company, develops antibody drug conjugates (ADC) for cancer patients with unmet need. It develops XMT-1592, a Dolasynthen ADC targeting NaPi2b-expressing tumor cells, which is in phase I clinical trial for the treatment of ovarian cancer and NSCLC adenocarcinoma. The company also develops XMT-1660, a B7-H4-targeted Dolasynthen ADC candidate; and XMT-2056, an immunosynthen development candidate. It has a strategic research and development partnerships with Merck KGaA and Asana BioSciences, LLC for the development of ADC product candidates utilizing Fleximer. The company was formerly known as Nanopharma Corp. and changed its name to Mersana Therapeutics, Inc. in November 2005. Mersana Therapeutics, Inc. was incorporated in 2001 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue$40M+9.9%
  • EBITDA-$72M+57.7%
  • Net Income-$69M+59.7%
  • EPS (Diluted)-14.12+61.8%
  • Gross Margin100%
  • EBITDA Margin-177.07%+61.5%
  • Operating Margin-181.09%+61.0%
  • Net Margin-170.86%+63.3%
  • ROE-505.14%-89.7%

MRSN Key Insights

Mersana Therapeutics, Inc. (MRSN) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 97 (top 3%)
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

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MRSN Price & Volume

Mersana Therapeutics, Inc. (MRSN) stock price & volume — 10-year historical chart

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MRSN Growth Metrics

Mersana Therapeutics, Inc. (MRSN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-0.78%
3 Years880.21%
TTM-4.76%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM6.08%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM8.03%

Return on Capital

10 Years-113.61%
5 Years-84.96%
3 Years-81.95%
Last Year-59.96%

MRSN Recent Earnings

Mersana Therapeutics, Inc. (MRSN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 5/12 qtrs (45%)
Q2 2026Latest
Mar 2, 2026
Metric
Actual
Est
EPS
$2.75+10.0%
$3.05
Rev
—
$5M
Q4 2025
Nov 14, 2025
Metric
Actual
Est
EPS
$1.51-4.9%
$1.44
Rev
$11M+442.3%
$2M
Q3 2025
Aug 13, 2025
Metric
Actual
Est
EPS
$4.08-8.8%
$3.75
Rev
$3M-71.2%
$11M
Q2 2025
May 15, 2025
Metric
Actual
Est
EPS
$4.75+9.5%
$5.25
Rev
$3M-55.0%
$6M
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 2, 2026
$2.75vs $3.05+10.0%
—vs $5M
Q4 2025Nov 14, 2025
$1.51vs $1.44-4.9%
$11Mvs $2M+442.3%
Q3 2025Aug 13, 2025
$4.08vs $3.75-8.8%
$3Mvs $11M-71.2%
Q2 2025May 15, 2025
$4.75vs $5.25+9.5%
$3Mvs $6M-55.0%
Based on last 12 quarters of dataView full earnings history →

MRSN Peer Comparison

Mersana Therapeutics, Inc. (MRSN) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
Institutional Holdings
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.45B24.31-7.39-4.26%-156.36%-68.97%0.16
SNDX logoSNDXSyndax Pharmaceuticals, Inc.Direct Competitor1.68B19.00-5.786.28%-112.01%-256.66%5.36
AGEN logoAGENAgenus Inc.Direct Competitor124.93M3.00-882.3510.37%52.16%
TGTX logoTGTXTG Therapeutics, Inc.Direct Competitor8.15B53.2219.2187.32%65.95%87.36%0.40
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.19B60.98-6.27-43.89%-284.18%-87%1.66
ARVN logoARVNArvinas, Inc.Product Competitor494.88M7.67-5.99-0.3%-247.54%-44.39%0.02
BCAB logoBCABBioAtla, Inc.Product Competitor4.61M3.66-0.07-81.82%-25.31%
BYSI logoBYSIBeyondSpring Inc.Product Competitor66.2M1.61-8.05

Compare MRSN vs Peers

Mersana Therapeutics, Inc. (MRSN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RCUS

Most directly comparable listed peer for MRSN.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare MRSN against a more recognizable public peer.

Peer Set

Compare Top 5

vs RCUS, SNDX, AGEN, TGTX

MRSN Income Statement

Mersana Therapeutics, Inc. (MRSN) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue
25.17M17.55M10.59M42.12M828K43K26.58M36.85M40.5M33.18M
Revenue Growth %
142.99%-30.3%-39.62%297.61%-98.03%-94.81%61716.28%38.65%9.88%-4.76%
Cost of Goods Sold
32.01M928K59.91M067.04M0000287K
COGS % of Revenue
127.16%5.29%565.56%-8096.14%-----
Gross Profit
-6.84M▲ 0%
16.62M▲ 343.0%
-49.32M▼ 396.8%
42.12M▲ 185.4%
-66.21M▼ 257.2%
43K▲ 100.1%
26.58M▲ 61716.3%
36.85M▲ 38.7%
40.5M▲ 9.9%
32.89M▲ 0%
Gross Margin %
-27.16%94.71%-465.56%100%-7996.14%100%100%100%100%99.13%
Gross Profit Growth %
37.81%343.05%-396.81%185.41%-257.18%100.06%61716.28%38.65%9.88%-
Operating Expenses
38.99M57.16M76.25M72.32M88.94M168.9M230.35M207.81M113.83M100.27M
OpEx % of Revenue
154.91%325.8%719.74%171.69%10741.3%392793.02%866.59%563.86%281.09%-
Selling, General & Admin
6.98M10.46M16.33M17.28M21.9M36.89M56.96M59.54M40.81M31.53M
SG&A % of Revenue
27.75%59.63%154.18%41.03%2645.17%85786.05%214.3%161.56%100.78%-
Research & Development
32.01M46.7M59.91M55.04M67.04M132.01M173.38M148.27M73.02M69.03M
R&D % of Revenue
127.16%266.17%565.56%130.67%8096.14%307006.98%652.29%402.3%180.31%-
Other Operating Expenses
001.4M000000-287K
Operating Income
-13.82M▲ 0%
-39.62M▼ 186.6%
-65.66M▼ 65.7%
-30.2M▲ 54.0%
-155.15M▼ 413.7%
-168.86M▼ 8.8%
-203.77M▼ 20.7%
-170.96M▲ 16.1%
-73.34M▲ 57.1%
-67.38M▲ 0%
Operating Margin %
-54.91%-225.8%-619.74%-71.69%-18737.44%-392693.02%-766.59%-463.86%-181.09%-203.06%
Operating Income Growth %
15.42%-186.64%-65.72%54%-413.73%-8.84%-20.67%16.1%57.1%-
EBITDA
-13.17M-38.69M-64.4M-28.95M-154.14M-168M-202.84M-169.44M-71.71M-66.29M
EBITDA Margin %
-52.31%-220.51%-607.87%-68.74%-18615.46%-390704.65%-763.1%-459.75%-177.07%-199.79%
EBITDA Growth %
17.94%-193.86%-66.45%55.04%-432.33%-9%-20.74%16.47%57.68%14.77%
D&A (Non-Cash Add-back)
655K928K1.26M1.25M1.01M855K927K1.52M1.63M1.09M
EBIT
-13.82M-38.71M-64.26M-27.97M-88.11M-168.79M-200.88M-167.6M-64.9M-67.33M
Net Interest Income
121K910K1.4M1.99M65K-1.2M-445K8M4.56M1.43M
Interest Income
121K910K1.4M2.23M424K65K2.88M12.07M8.44M4.17M
Interest Expense
000234K359K1.27M3.33M4.07M3.87M2.75M
Other Income/Expense
121K910K1.4M1.99M67.1M-1.2M-445K-713K4.56M-2.71M
Pretax Income
-13.7M▲ 0%
-38.71M▼ 182.5%
-64.26M▼ 66.0%
-28.21M▲ 56.1%
-88.05M▼ 212.1%
-170.06M▼ 93.2%
-204.21M▼ 20.1%
-171.67M▲ 15.9%
-68.77M▲ 59.9%
-70.08M▲ 0%
Pretax Margin %
-54.43%-220.62%-606.54%-66.97%-10633.45%-395488.37%-768.26%-465.8%-169.82%-211.21%
Income Tax
00000000418K0
Effective Tax Rate %
0%0%0%0%0%0%0%0%-0.61%0%
Net Income
-13.7M▲ 0%
-38.71M▼ 182.5%
-64.26M▼ 66.0%
-28.21M▲ 56.1%
-88.05M▼ 212.1%
-170.06M▼ 93.2%
-204.21M▼ 20.1%
-171.67M▲ 15.9%
-69.19M▲ 59.7%
-70.08M▲ 0%
Net Margin %
-54.43%-220.62%-606.54%-66.97%-10633.45%-395488.37%-768.26%-465.8%-170.86%-211.21%
Net Income Growth %
16.61%-182.53%-66.01%56.1%-212.13%-93.15%-20.08%15.94%59.69%6.08%
Net Income (Continuing)
-13.7M-38.71M-64.26M-28.21M-88.05M-170.06M-204.21M-171.67M-69.19M-70.08M
Discontinued Operations
0000000000
Minority Interest
0000000000
EPS (Diluted)
-19.58▲ 0%
-42.95▼ 119.4%
-69.75▼ 62.4%
-16.21▲ 76.8%
-35.80▼ 120.9%
-60.24▼ 68.3%
-54.51▲ 9.5%
-36.96▲ 32.2%
-14.12▲ 61.8%
-14.05▲ 0%
EPS Growth %
16.61%-119.36%-62.4%76.76%-120.85%-68.27%9.51%32.2%61.8%8.03%
EPS (Basic)
-19.58-43.00-69.75-16.25-35.80-60.24-54.51-36.96-14.12-
Diluted Shares Outstanding
699.73K901.17K921.29K1.74M2.46M2.82M3.75M4.64M4.9M4.99M
Basic Shares Outstanding
699.73K900.14K921.29K1.74M2.46M2.82M3.75M4.64M4.9M4.99M
Dividend Payout Ratio
----------

MRSN Balance Sheet

Mersana Therapeutics, Inc. (MRSN) balance sheet — assets, liabilities & shareholders' equity

MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets
102.17M117.54M70.13M101.33M258.58M188.9M319.22M214.06M136.9M59.99M
Cash & Short-Term Investments
100.3M114.73M70.13M99.79M255.09M177.95M280.71M209.08M134.62M56.39M
Cash Only
100.3M26.59M59.63M62.35M255.09M177.95M128.88M174.56M107.75M56.39M
Short-Term Investments
088.14M10.5M37.44M00151.83M34.52M26.87M0
Accounts Receivable
1.05M784K459K00030M00168K
Days Sales Outstanding
15.2416.3115.81---411.95--1.19
Inventory
00-4.17M0000000
Days Inventory Outstanding
----------
Other Current Assets
02.02M3.71M1.54M010.95M8.51M4.97M2.28M3.43M
Total Non-Current Assets
2.91M13.17M8.37M6.21M14.82M17.21M15.12M12M7.76M2.7M
Property, Plant & Equipment
2.48M2.32M2.69M4.76M12.67M14.86M14.46M11.53M6.78M2.2M
Fixed Asset Turnover
10.14x7.57x3.93x8.85x0.07x0.00x1.84x3.20x5.97x7.16x
Goodwill
0000000000
Intangible Assets
0000000000
Long-Term Investments
321K10.48M371K321K321478K000657K
Other Non-Current Assets
110K371K5.31M1.13M2.15M1.88M661K478K978K500K
Total Assets
105.09M▲ 0%
130.72M▲ 24.4%
78.5M▼ 39.9%
107.54M▲ 37.0%
273.4M▲ 154.2%
206.11M▼ 24.6%
334.34M▲ 62.2%
226.06M▼ 32.4%
144.66M▼ 36.0%
62.69M▲ 0%
Asset Turnover
0.24x0.13x0.13x0.39x0.00x0.00x0.08x0.16x0.28x0.33x
Asset Growth %
629.31%24.39%-39.94%36.99%154.23%-24.61%62.21%-32.39%-36.01%-195.12%
Total Current Liabilities
28.39M31.88M69.42M24.07M30M47.52M91.53M63.64M62.46M43.27M
Accounts Payable
2.07M3.07M10.73M7.3M8.34M12.32M13.95M7.32M4.33M2.39M
Days Payables Outstanding
23.581.21K65.35-45.41----4.46K
Short-Term Debt
000667K93K002.08M12.5M2.29M
Deferred Revenue (Current)
22.73M21.64M46.2M4.82M3.99M3.94M30.61M28.15M22.17M89.84M
Other Current Liabilities
1.31M4.13M9.46M5.04M10.83M21.64M990K13.88M12.26M14.81M
Current Ratio
3.60x3.69x1.01x4.21x8.62x3.97x3.49x3.36x2.19x1.39x
Quick Ratio
3.60x3.69x1.07x4.21x8.62x3.97x3.49x3.36x2.19x1.39x
Cash Conversion Cycle
----------4.46K
Total Non-Current Liabilities
132.32M28.84M282K5.15M15.31M36.85M150.75M125.52M91.71M78.95M
Long-Term Debt
0004.2M4.98M24.63M24.93M23.15M10.95M0
Capital Lease Obligations
000677K10.16M11.25M8.57M5.2M1.29M1.55M
Deferred Tax Liabilities
0000000000
Other Non-Current Liabilities
94.75M67K282K275K174K974K203K1K8K78.95M
Total Liabilities
160.71M60.72M69.71M29.22M45.31M84.37M242.28M189.16M154.17M122.22M
Total Debt
0007.76M16.66M38.18M36.3M33.83M28.6M2.29M
Net Debt
-100.3M-26.59M-59.63M-54.59M-238.43M-139.77M-92.58M-140.73M-79.15M-54.1M
Debt / Equity
---0.10x0.07x0.31x0.39x0.92x--0.04x
Debt / EBITDA
----------0.03x
Net Debt / EBITDA
---------0.82x
Interest Coverage
----129.06x-432.16x-133.27x-61.23x-41.97x-18.93x-24.52x
Total Equity
-55.62M▲ 0%
69.99M▲ 225.8%
8.79M▼ 87.4%
78.32M▲ 790.5%
228.09M▲ 191.2%
121.74M▼ 46.6%
92.06M▼ 24.4%
36.9M▼ 59.9%
-9.51M▼ 125.8%
-59.54M▲ 0%
Equity Growth %
-30.28%225.85%-87.43%790.48%191.23%-46.63%-24.38%-59.91%-125.77%-6842.33%
Book Value per Share
-79.4977.679.5545.0292.7443.1224.577.95-1.94-11.94
Total Shareholders' Equity
-55.62M69.99M8.79M78.32M228.09M121.74M92.06M36.9M-9.51M-59.54M
Common Stock
1K3K3K5K7K7K11K12K12K0
Retained Earnings
-59.17M-97.88M-164.17M-192.37M-280.42M-450.48M-654.69M-826.36M-895.55M-951.52M
Treasury Stock
0000000000
Accumulated OCI
-4.21M-149K-8K25K00-152K11K10K0
Minority Interest
0000000000

MRSN Cash Flow Statement

Mersana Therapeutics, Inc. (MRSN) cash flow — operating, investing & free cash flow history

MetricDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations
31.59M-42.68M-55.22M-67.74M-74.7M-139.99M-49.36M-168.88M-82.34M-74.37M
Operating CF Margin %
125.49%-243.25%-521.2%-160.82%-9021.26%-325553.49%-185.71%-458.23%-203.32%-
Operating CF Growth %
427.81%-235.11%-29.38%-22.69%-10.26%-87.41%64.74%-242.12%51.24%109.34%
Net Income
-13.7M-38.71M-64.26M-28.21M-88.05M-170.06M-204.21M-171.67M-69.19M-70.08M
Depreciation & Amortization
655K928K1.26M1.25M1.01M855K927K1.52M1.63M1.09M
Stock-Based Compensation
668K1.42M3.88M4.87M7.17M18.41M21.52M21.14M16.46M9.26M
Deferred Taxes
-102K-134K-386K-222K000000
Other Non-Cash Items
102K-159K110K103K62K723K-699K-1.1M-496K3.83M
Working Capital Changes
43.97M-6.03M4.18M-45.53M5.11M10.09M133.1M-18.76M-30.74M-18.47M
Change in Receivables
-411K267K325K459K00-30M30M01.1M
Change in Inventory
1.42M2.42M2.61M-1.5M000000
Change in Payables
-325K1.33M7.38M-3.11M942K483K947K-6.08M-2.86M360K
Cash from Investing
-1.08M-99.62M87.19M-27.29M37.03M-648K-152.72M119.88M11.44M77.77M
Capital Expenditures
-1.08M-1.14M-1.37M-605K-473K-648K-2.2M-2.17M-132K0
CapEx % of Revenue
4.31%6.51%12.93%1.44%57.13%1506.98%8.27%5.88%0.33%0%
Acquisitions
00026.69M00150.52M00395K
Investments
----------
Other Investing
0-98.48M88.56M-26.69M00-150.52M00372K
Cash from Financing
58.26M68.6M1.06M97.7M230.41M63.65M153.02M94.67M4.09M-25.87M
Debt Issued (Net)
0004.88M-313K18.34M-272K-262K-2.23M-26.13M
Equity Issued (Net)
1000K1000K01000K1000K1000K1000K1000K1000K257K
Dividends Paid
0000000000
Share Repurchases
00146K0000000
Other Financing
105K452K1.06M664K3.7M2.22M2.4M1.4M542K0
Net Change in Cash
88.76M▲ 0%
-73.71M▼ 183.0%
33.04M▲ 144.8%
2.67M▼ 91.9%
192.74M▲ 7127.0%
-76.99M▼ 139.9%
-49.06M▲ 36.3%
45.68M▲ 193.1%
-66.81M▼ 246.3%
-22.48M▲ 0%
Free Cash Flow
30.5M▲ 0%
-43.82M▼ 243.7%
-56.59M▼ 29.1%
-68.35M▼ 20.8%
-75.17M▼ 10.0%
-140.64M▼ 87.1%
-51.56M▲ 63.3%
-171.05M▼ 231.7%
-82.47M▲ 51.8%
-74.37M▲ 0%
FCF Margin %
121.19%-249.77%-534.13%-162.26%-9078.38%-327060.47%-193.97%-464.12%-203.65%-224.14%
FCF Growth %
397.45%-243.66%-29.13%-20.79%-9.98%-87.09%63.34%-231.75%51.78%22.18%
FCF per Share
43.59-48.63-61.42-39.29-30.56-49.81-13.76-36.83-16.83-14.91
FCF Conversion (FCF/Net Income)
-2.31x1.10x0.86x2.40x0.85x0.82x0.24x0.98x1.19x1.06x
Interest Paid
0000234K0003.47M1.02M
Taxes Paid
00000000418K0

MRSN Key Ratios

Mersana Therapeutics, Inc. (MRSN) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)
--538.53%-163.11%-64.76%-57.47%-97.22%-191.03%-266.24%-505.14%183.15%
Return on Invested Capital (ROIC)
-----1738.14%----48.09%
Gross Margin
-27.16%94.71%-465.56%100%-7996.14%100%100%100%100%99.13%
Net Margin
-54.43%-220.62%-606.54%-66.97%-10633.45%-395488.37%-768.26%-465.8%-170.86%-211.21%
Debt / Equity
---0.10x0.07x0.31x0.39x0.92x--0.04x
Interest Coverage
----129.06x-432.16x-133.27x-61.23x-41.97x-18.93x-24.52x
FCF Conversion
-2.31x1.10x0.86x2.40x0.85x0.82x0.24x0.98x1.19x1.06x
Revenue Growth
142.99%-30.3%-39.62%297.61%-98.03%-94.81%61716.28%38.65%9.88%-4.76%
Related:MRSN Dividend History·MRSN Revenue History·MRSN Price History·MRSN P/E History·MRSN Financial Ratios·MRSN Institutional Holders

MRSN SEC Filings & Documents

Mersana Therapeutics, Inc. (MRSN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jan 6, 2026·SEC

Material company update

Nov 14, 2025·SEC

Material company update

Nov 13, 2025·SEC

10-K Annual Reports

2
FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 14, 2025·SEC

FY 2025

Aug 13, 2025·SEC

FY 2025

May 15, 2025·SEC

MRSN Frequently Asked Questions

Mersana Therapeutics, Inc. (MRSN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Mersana Therapeutics, Inc. (MRSN) reported $33.2M in revenue for fiscal year 2024. This represents a 220% increase from $10.4M in 2015.

Mersana Therapeutics, Inc. (MRSN) grew revenue by 9.9% over the past year. This is steady growth.

Mersana Therapeutics, Inc. (MRSN) reported a net loss of $70.1M for fiscal year 2024.

Dividend & Returns

Mersana Therapeutics, Inc. (MRSN) has a return on equity (ROE) of -505.1%. Negative ROE indicates the company is unprofitable.

Mersana Therapeutics, Inc. (MRSN) had negative free cash flow of $74.4M in fiscal year 2024, likely due to heavy capital investments.

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