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MRSN logoMersana Therapeutics, Inc.(MRSN)Earnings, Financials & Key Ratios

MRSN•NASDAQ
$29.08
$145M mkt cap·Price updated Apr 24, 2026
SectorHealthcareIndustryBiotechnologySub-IndustryOncology Therapeutics Developers
AboutMersana Therapeutics, Inc., a clinical stage biopharmaceutical company, develops antibody drug conjugates (ADC) for cancer patients with unmet need. It develops XMT-1592, a Dolasynthen ADC targeting NaPi2b-expressing tumor cells, which is in phase I clinical trial for the treatment of ovarian cancer and NSCLC adenocarcinoma. The company also develops XMT-1660, a B7-H4-targeted Dolasynthen ADC candidate; and XMT-2056, an immunosynthen development candidate. It has a strategic research and development partnerships with Merck KGaA and Asana BioSciences, LLC for the development of ADC product candidates utilizing Fleximer. The company was formerly known as Nanopharma Corp. and changed its name to Mersana Therapeutics, Inc. in November 2005. Mersana Therapeutics, Inc. was incorporated in 2001 and is headquartered in Cambridge, Massachusetts.Show more
  • Revenue$40M+9.9%
  • EBITDA-$72M+57.7%
  • Net Income-$69M+59.7%
  • EPS (Diluted)-14.12+61.8%
  • Gross Margin100%
  • EBITDA Margin-177.07%+61.5%
  • Operating Margin-181.09%+61.0%
  • Net Margin-170.86%+63.3%
  • ROE-505.14%-89.7%
  • Interest Coverage-18.93+54.9%
Technical→

MRSN Key Insights

Mersana Therapeutics, Inc. (MRSN) fundamental analysis — strengths, weaknesses & financial health based on data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 97 (top 3%)
  • ✓Trading near 52-week high

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

MRSN Price & Volume

Mersana Therapeutics, Inc. (MRSN) stock price & volume — 10-year historical chart

Loading chart...

MRSN Growth Metrics

Mersana Therapeutics, Inc. (MRSN) revenue, earnings & EPS growth — 3, 5 & 10-year CAGR

Revenue CAGR

10 Years-
5 Years-0.78%
3 Years880.21%
TTM-4.76%

Profit CAGR

10 Years-
5 Years-
3 Years-
TTM6.08%

EPS CAGR

10 Years-
5 Years-
3 Years-
TTM8.03%

Return on Capital

10 Years-113.61%
5 Years-84.96%
3 Years-81.95%
Last Year-59.96%

MRSN Recent Earnings

Mersana Therapeutics, Inc. (MRSN) EPS & revenue vs analyst estimates — last 4 quarters

Full history →
●Beat EPS 6/12 qtrs (50%)●Beat Revenue 5/12 qtrs (45%)
Q2 2026Latest
Mar 2, 2026
EPS
$2.75
Est $3.05
+10.0%
Revenue
—
Est $5M
Q4 2025
Nov 14, 2025
EPS
$1.51
Est $1.44
-4.9%
Revenue
$11M
Est $2M
+442.3%
Q3 2025
Aug 13, 2025
EPS
$4.08
Est $3.75
-8.8%
Revenue
$3M
Est $11M
-71.2%
Q2 2025
May 15, 2025
EPS
$4.75
Est $5.25
+9.5%
Revenue
$3M
Est $6M
-55.0%
QuarterDateEPS (Act vs Est)Revenue (Act vs Est)
Q2 2026LatestMar 2, 2026
$2.75vs $3.05+10.0%
—vs $5M
Q4 2025Nov 14, 2025
$1.51vs $1.44-4.9%
$11Mvs $2M+442.3%
Q3 2025Aug 13, 2025
$4.08vs $3.75-8.8%
$3Mvs $11M-71.2%
Q2 2025May 15, 2025
$4.75vs $5.25+9.5%
$3Mvs $6M-55.0%
Based on last 12 quarters of dataView full earnings history →

MRSN Peer Comparison

Mersana Therapeutics, Inc. (MRSN) competitors in Oncology Therapeutics Developers — business model, growth, and fundamentals comparison

Select Columns
Stock Universe
Valuation
Growth
Profitability
Financial Health
Dividends & Buybacks
Price Performance
Technical
Fundamentals ($)
Sector-Specific
CompanyMarket CapStock PriceP/E Ratio (TTM)Revenue Growth 1YNet MarginReturn on Equity (ROE)FCF YieldDebt / Equity
RCUS logoRCUSArcus Biosciences, Inc.Direct Competitor2.62B26.00-7.90-4.26%-156.36%-68.97%0.16
SNDX logoSNDXSyndax Pharmaceuticals, Inc.Direct Competitor1.82B20.65-6.286.28%-112.01%-256.66%5.36
AGEN logoAGENAgenus Inc.Direct Competitor137.4M3.89-1144.1210.37%0.1%
TGTX logoTGTXTG Therapeutics, Inc.Direct Competitor6.7B41.9715.1587.32%65.95%87.36%0.40
NKTR logoNKTRNektar TherapeuticsDirect Competitor1.67B85.09-8.75-43.89%-192.87%-356.81%0.95
ARVN logoARVNArvinas, Inc.Product Competitor656.24M10.26-8.02-0.3%-30.77%-14.25%0.02
BCAB logoBCABBioAtla, Inc.Product Competitor5.29M4.50-0.09-81.82%-29.8%
BYSI logoBYSIBeyondSpring Inc.Product Competitor65.73M1.63-5.82

Compare MRSN vs Peers

Mersana Therapeutics, Inc. (MRSN) vs competitors — business, growth, and fundamentals comparison against the closest industry rivals.

Closest Rival

vs RCUS

Most directly comparable listed peer for MRSN.

Scale Benchmark

vs ABBV

Larger-name benchmark to compare MRSN against a more recognizable public peer.

Peer Set

Compare Top 5

vs RCUS, SNDX, AGEN, TGTX

MRSN Income Statement

Mersana Therapeutics, Inc. (MRSN) annual income statement — 10-year revenue, gross profit & net income history

10Y historyFree accessUpdated daily
Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Sales/Revenue25.17M17.55M10.59M42.12M828K43K26.58M36.85M40.5M33.18M
Revenue Growth %142.99%-30.3%-39.62%297.61%-98.03%-94.81%61716.28%38.65%9.88%-4.76%
Cost of Goods Sold32.01M928K59.91M067.04M0000287K
COGS % of Revenue127.16%5.29%565.56%-8096.14%-----
Gross Profit
-6.84M▲ 0%
16.62M▲ 343.0%
-49.32M▼ 396.8%
42.12M▲ 185.4%
-66.21M▼ 257.2%
43K▲ 100.1%
26.58M▲ 61716.3%
36.85M▲ 38.7%
40.5M▲ 9.9%
32.89M▲ 0%
Gross Margin %-27.16%94.71%-465.56%100%-7996.14%100%100%100%100%99.13%
Gross Profit Growth %37.81%343.05%-396.81%185.41%-257.18%100.06%61716.28%38.65%9.88%-
Operating Expenses38.99M57.16M76.25M72.32M88.94M168.9M230.35M207.81M113.83M100.27M
OpEx % of Revenue154.91%325.8%719.74%171.69%10741.3%392793.02%866.59%563.86%281.09%-
Selling, General & Admin6.98M10.46M16.33M17.28M21.9M36.89M56.96M59.54M40.81M31.53M
SG&A % of Revenue27.75%59.63%154.18%41.03%2645.17%85786.05%214.3%161.56%100.78%-
Research & Development32.01M46.7M59.91M55.04M67.04M132.01M173.38M148.27M73.02M69.03M
R&D % of Revenue127.16%266.17%565.56%130.67%8096.14%307006.98%652.29%402.3%180.31%-
Other Operating Expenses001.4M000000-287K
Operating Income
-13.82M▲ 0%
-39.62M▼ 186.6%
-65.66M▼ 65.7%
-30.2M▲ 54.0%
-155.15M▼ 413.7%
-168.86M▼ 8.8%
-203.77M▼ 20.7%
-170.96M▲ 16.1%
-73.34M▲ 57.1%
-67.38M▲ 0%
Operating Margin %-54.91%-225.8%-619.74%-71.69%-18737.44%-392693.02%-766.59%-463.86%-181.09%-203.06%
Operating Income Growth %15.42%-186.64%-65.72%54%-413.73%-8.84%-20.67%16.1%57.1%-
EBITDA-13.17M-38.69M-64.4M-28.95M-154.14M-168M-202.84M-169.44M-71.71M-66.29M
EBITDA Margin %-52.31%-220.51%-607.87%-68.74%-18615.46%-390704.65%-763.1%-459.75%-177.07%-199.79%
EBITDA Growth %17.94%-193.86%-66.45%55.04%-432.33%-9%-20.74%16.47%57.68%14.77%
D&A (Non-Cash Add-back)655K928K1.26M1.25M1.01M855K927K1.52M1.63M1.09M
EBIT-13.82M-38.71M-64.26M-27.97M-88.11M-168.79M-200.88M-167.6M-64.9M-67.33M
Net Interest Income121K910K1.4M1.99M65K-1.2M-445K8M4.56M1.43M
Interest Income121K910K1.4M2.23M424K65K2.88M12.07M8.44M4.17M
Interest Expense000234K359K1.27M3.33M4.07M3.87M2.75M
Other Income/Expense121K910K1.4M1.99M67.1M-1.2M-445K-713K4.56M-2.71M
Pretax Income
-13.7M▲ 0%
-38.71M▼ 182.5%
-64.26M▼ 66.0%
-28.21M▲ 56.1%
-88.05M▼ 212.1%
-170.06M▼ 93.2%
-204.21M▼ 20.1%
-171.67M▲ 15.9%
-68.77M▲ 59.9%
-70.08M▲ 0%
Pretax Margin %-54.43%-220.62%-606.54%-66.97%-10633.45%-395488.37%-768.26%-465.8%-169.82%-211.21%
Income Tax00000000418K0
Effective Tax Rate %0%0%0%0%0%0%0%0%-0.61%0%
Net Income
-13.7M▲ 0%
-38.71M▼ 182.5%
-64.26M▼ 66.0%
-28.21M▲ 56.1%
-88.05M▼ 212.1%
-170.06M▼ 93.2%
-204.21M▼ 20.1%
-171.67M▲ 15.9%
-69.19M▲ 59.7%
-70.08M▲ 0%
Net Margin %-54.43%-220.62%-606.54%-66.97%-10633.45%-395488.37%-768.26%-465.8%-170.86%-211.21%
Net Income Growth %16.61%-182.53%-66.01%56.1%-212.13%-93.15%-20.08%15.94%59.69%6.08%
Net Income (Continuing)-13.7M-38.71M-64.26M-28.21M-88.05M-170.06M-204.21M-171.67M-69.19M-70.08M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)
-19.58▲ 0%
-42.95▼ 119.4%
-69.75▼ 62.4%
-16.21▲ 76.8%
-35.80▼ 120.9%
-60.24▼ 68.3%
-54.51▲ 9.5%
-36.96▲ 32.2%
-14.12▲ 61.8%
-14.05▲ 0%
EPS Growth %16.61%-119.36%-62.4%76.76%-120.85%-68.27%9.51%32.2%61.8%8.03%
EPS (Basic)-19.58-43.00-69.75-16.25-35.80-60.24-54.51-36.96-14.12-
Diluted Shares Outstanding699.73K901.17K921.29K1.74M2.46M2.82M3.75M4.64M4.9M4.99M
Basic Shares Outstanding699.73K900.14K921.29K1.74M2.46M2.82M3.75M4.64M4.9M4.99M
Dividend Payout Ratio----------

MRSN Balance Sheet

Mersana Therapeutics, Inc. (MRSN) balance sheet — assets, liabilities & shareholders' equity

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Total Current Assets102.17M117.54M70.13M101.33M258.58M188.9M319.22M214.06M136.9M59.99M
Cash & Short-Term Investments100.3M114.73M70.13M99.79M255.09M177.95M280.71M209.08M134.62M56.39M
Cash Only100.3M26.59M59.63M62.35M255.09M177.95M128.88M174.56M107.75M56.39M
Short-Term Investments088.14M10.5M37.44M00151.83M34.52M26.87M0
Accounts Receivable1.05M784K459K00030M00168K
Days Sales Outstanding15.2416.3115.81---411.95--1.19
Inventory00-4.17M0000000
Days Inventory Outstanding----------
Other Current Assets02.02M3.71M1.54M010.95M8.51M4.97M2.28M3.43M
Total Non-Current Assets2.91M13.17M8.37M6.21M14.82M17.21M15.12M12M7.76M2.7M
Property, Plant & Equipment2.48M2.32M2.69M4.76M12.67M14.86M14.46M11.53M6.78M2.2M
Fixed Asset Turnover10.14x7.57x3.93x8.85x0.07x0.00x1.84x3.20x5.97x7.16x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments321K10.48M371K321K321478K000657K
Other Non-Current Assets110K371K5.31M1.13M2.15M1.88M661K478K978K1.98M
Total Assets
105.09M▲ 0%
130.72M▲ 24.4%
78.5M▼ 39.9%
107.54M▲ 37.0%
273.4M▲ 154.2%
206.11M▼ 24.6%
334.34M▲ 62.2%
226.06M▼ 32.4%
144.66M▼ 36.0%
62.69M▲ 0%
Asset Turnover0.24x0.13x0.13x0.39x0.00x0.00x0.08x0.16x0.28x0.33x
Asset Growth %629.31%24.39%-39.94%36.99%154.23%-24.61%62.21%-32.39%-36.01%-195.12%
Total Current Liabilities28.39M31.88M69.42M24.07M30M47.52M91.53M63.64M62.46M43.27M
Accounts Payable2.07M3.07M10.73M7.3M8.34M12.32M13.95M7.32M4.33M2.39M
Days Payables Outstanding23.581.21K65.35-45.41----4.46K
Short-Term Debt000667K93K002.08M12.5M2.29M
Deferred Revenue (Current)22.73M21.64M46.2M4.82M3.99M3.94M30.61M28.15M22.17M89.84M
Other Current Liabilities1.31M4.13M9.46M5.04M10.83M21.64M990K13.88M12.26M14.81M
Current Ratio3.60x3.69x1.01x4.21x8.62x3.97x3.49x3.36x2.19x2.19x
Quick Ratio3.60x3.69x1.07x4.21x8.62x3.97x3.49x3.36x2.19x2.19x
Cash Conversion Cycle----------4.46K
Total Non-Current Liabilities132.32M28.84M282K5.15M15.31M36.85M150.75M125.52M91.71M78.95M
Long-Term Debt0004.2M4.98M24.63M24.93M23.15M10.95M0
Capital Lease Obligations000677K10.16M11.25M8.57M5.2M1.29M1.55M
Deferred Tax Liabilities0000000000
Other Non-Current Liabilities94.75M67K282K275K174K974K203K1K8K78.96M
Total Liabilities160.71M60.72M69.71M29.22M45.31M84.37M242.28M189.16M154.17M122.22M
Total Debt0007.76M16.66M38.18M36.3M33.83M28.6M2.29M
Net Debt-100.3M-26.59M-59.63M-54.59M-238.43M-139.77M-92.58M-140.73M-79.15M-54.1M
Debt / Equity---0.10x0.07x0.31x0.39x0.92x--0.04x
Debt / EBITDA----------0.03x
Net Debt / EBITDA---------0.82x
Interest Coverage----129.06x-432.16x-133.27x-61.23x-41.97x-18.93x-24.52x
Total Equity
-55.62M▲ 0%
69.99M▲ 225.8%
8.79M▼ 87.4%
78.32M▲ 790.5%
228.09M▲ 191.2%
121.74M▼ 46.6%
92.06M▼ 24.4%
36.9M▼ 59.9%
-9.51M▼ 125.8%
-59.54M▲ 0%
Equity Growth %-30.28%225.85%-87.43%790.48%191.23%-46.63%-24.38%-59.91%-125.77%-6842.33%
Book Value per Share-79.4977.679.5545.0292.7443.1224.577.95-1.94-11.94
Total Shareholders' Equity-55.62M69.99M8.79M78.32M228.09M121.74M92.06M36.9M-9.51M-59.54M
Common Stock1K3K3K5K7K7K11K12K12K0
Retained Earnings-59.17M-97.88M-164.17M-192.37M-280.42M-450.48M-654.69M-826.36M-895.55M-951.52M
Treasury Stock0000000000
Accumulated OCI-4.21M-149K-8K25K00-152K11K10K0
Minority Interest0000000000

MRSN Cash Flow Statement

Mersana Therapeutics, Inc. (MRSN) cash flow — operating, investing & free cash flow history

Line itemDec'16Dec'17Dec'18Dec'19Dec'20Dec'21Dec'22Dec'23Dec'24TTM
Cash from Operations31.59M-42.68M-55.22M-67.74M-74.7M-139.99M-49.36M-168.88M-82.34M-82.34M
Operating CF Margin %125.49%-243.25%-521.2%-160.82%-9021.26%-325553.49%-185.71%-458.23%-203.32%-
Operating CF Growth %427.81%-235.11%-29.38%-22.69%-10.26%-87.41%64.74%-242.12%51.24%109.34%
Net Income-13.7M-38.71M-64.26M-28.21M-88.05M-170.06M-204.21M-171.67M-69.19M-70.08M
Depreciation & Amortization655K928K1.26M1.25M1.01M855K927K1.52M1.63M1.09M
Stock-Based Compensation668K1.42M3.88M4.87M7.17M18.41M21.52M21.14M16.46M9.26M
Deferred Taxes-102K-134K-386K-222K000000
Other Non-Cash Items102K-159K110K103K62K723K-699K-1.1M-496K3.83M
Working Capital Changes43.97M-6.03M4.18M-45.53M5.11M10.09M133.1M-18.76M-30.74M-18.47M
Change in Receivables-411K267K325K459K00-30M30M01.1M
Change in Inventory1.42M2.42M2.61M-1.5M000000
Change in Payables-325K1.33M7.38M-3.11M942K483K947K-6.08M-2.86M360K
Cash from Investing-1.08M-99.62M87.19M-27.29M37.03M-648K-152.72M119.88M11.44M77.77M
Capital Expenditures-1.08M-1.14M-1.37M-605K-473K-648K-2.2M-2.17M-132K0
CapEx % of Revenue4.31%6.51%12.93%1.44%57.13%1506.98%8.27%5.88%0.33%-
Acquisitions00026.69M00150.52M00395K
Investments----------
Other Investing0-98.48M88.56M-26.69M00-150.52M00372K
Cash from Financing58.26M68.6M1.06M97.7M230.41M63.65M153.02M94.67M4.09M-25.87M
Debt Issued (Net)0004.88M-313K18.34M-272K-262K-2.23M-26.13M
Equity Issued (Net)1000K1000K01000K1000K1000K1000K1000K1000K257K
Dividends Paid0000000000
Share Repurchases00146K0000000
Other Financing105K452K1.06M664K3.7M2.22M2.4M1.4M542K0
Net Change in Cash
88.76M▲ 0%
-73.71M▼ 183.0%
33.04M▲ 144.8%
2.67M▼ 91.9%
192.74M▲ 7127.0%
-76.99M▼ 139.9%
-49.06M▲ 36.3%
45.68M▲ 193.1%
-66.81M▼ 246.3%
-22.48M▲ 0%
Free Cash Flow
30.5M▲ 0%
-43.82M▼ 243.7%
-56.59M▼ 29.1%
-68.35M▼ 20.8%
-75.17M▼ 10.0%
-140.64M▼ 87.1%
-51.56M▲ 63.3%
-171.05M▼ 231.7%
-82.47M▲ 51.8%
-74.37M▲ 0%
FCF Margin %121.19%-249.77%-534.13%-162.26%-9078.38%-327060.47%-193.97%-464.12%-203.65%-224.14%
FCF Growth %397.45%-243.66%-29.13%-20.79%-9.98%-87.09%63.34%-231.75%51.78%22.18%
FCF per Share43.59-48.63-61.42-39.29-30.56-49.81-13.76-36.83-16.83-16.83
FCF Conversion (FCF/Net Income)-2.31x1.10x0.86x2.40x0.85x0.82x0.24x0.98x1.19x1.06x
Interest Paid0000234K0003.47M1.02M
Taxes Paid00000000418K0

MRSN Key Ratios

Mersana Therapeutics, Inc. (MRSN) financial ratios — P/E, ROE, debt and 30+ core market and balance-sheet ratios

Metric201620172018201920202021202220232024TTM
Return on Equity (ROE)--538.53%-163.11%-64.76%-57.47%-97.22%-191.03%-266.24%-505.14%183.15%
Return on Invested Capital (ROIC)-----1738.14%----48.09%
Gross Margin-27.16%94.71%-465.56%100%-7996.14%100%100%100%100%99.13%
Net Margin-54.43%-220.62%-606.54%-66.97%-10633.45%-395488.37%-768.26%-465.8%-170.86%-211.21%
Debt / Equity---0.10x0.07x0.31x0.39x0.92x--0.04x
Interest Coverage----129.06x-432.16x-133.27x-61.23x-41.97x-18.93x-24.52x
FCF Conversion-2.31x1.10x0.86x2.40x0.85x0.82x0.24x0.98x1.19x1.06x
Revenue Growth142.99%-30.3%-39.62%297.61%-98.03%-94.81%61716.28%38.65%9.88%-4.76%

MRSN SEC Filings & Documents

Mersana Therapeutics, Inc. (MRSN) SEC filings — annual & quarterly reports (10-K, 10-Q)

8-K Announcements

6
Material company update

Jan 6, 2026·SEC

Material company update

Nov 14, 2025·SEC

Material company update

Nov 13, 2025·SEC

10-K Annual Reports

2
FY 2025

Mar 3, 2025·SEC

FY 2024

Feb 28, 2024·SEC

10-Q Quarterly Reports

6
FY 2025

Nov 14, 2025·SEC

FY 2025

Aug 13, 2025·SEC

FY 2025

May 15, 2025·SEC

MRSN Frequently Asked Questions

Mersana Therapeutics, Inc. (MRSN) stock FAQ — growth, dividends, profitability & financials explained

Growth & Financials

Mersana Therapeutics, Inc. (MRSN) reported $33.2M in revenue for fiscal year 2024. This represents a 220% increase from $10.4M in 2015.

Mersana Therapeutics, Inc. (MRSN) grew revenue by 9.9% over the past year. This is steady growth.

Mersana Therapeutics, Inc. (MRSN) reported a net loss of $70.1M for fiscal year 2024.

Dividend & Returns

Mersana Therapeutics, Inc. (MRSN) has a return on equity (ROE) of -505.1%. Negative ROE indicates the company is unprofitable.

Mersana Therapeutics, Inc. (MRSN) had negative free cash flow of $74.4M in fiscal year 2024, likely due to heavy capital investments.

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