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Prothena Corporation plc (PRTA) 10-Year Financial Performance & Capital Metrics

PRTA • • Industrial / General
HealthcareBiotechnologyNeurology & CNS DisordersAlzheimer's & Neurodegenerative
AboutProthena Corporation plc, a late-stage clinical company, focuses on discovery and development of novel therapies for life-threatening diseases in the United States. The company is involved in developing Birtamimab, an investigational humanized antibody that is in Phase III clinical trial for the treatment of AL amyloidosis; Prasinezumab, a humanized monoclonal antibody, which is in Phase IIb clinical trial for the treatment of Parkinson's disease; PRX004 that completed Phase I clinical trial for the treatment of Transthyretin amyloidosis; and PRX005, which is in Phase I clinical trial for the treatment of Alzheimer's disease. Its discovery and preclinical programs include PRX012 for the treatment of Alzheimer's disease; and dual Aß-Tau vaccine for the treatment and prevention of Alzheimer's disease. Prothena Corporation plc has a license, development, and commercialization agreement with F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. to develop and commercialize antibodies that target alpha-synuclein; and a collaboration agreement with Bristol-Myers Squibb to develop antibodies. The company was founded in 2012 and is based in Dublin, Ireland.Show more
  • Revenue $135M +47.9%
  • EBITDA -$154M +19.2%
  • Net Income -$122M +16.8%
  • EPS (Diluted) -2.27 +17.8%
  • Gross Margin 100%
  • EBITDA Margin -113.7% +45.4%
  • Operating Margin -114.36% +45.3%
  • Net Margin -90.49% +43.8%
  • ROE -23.34% +6.1%
  • ROIC -439.41%
  • Debt/Equity 0.02 +5.6%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Company is almost debt free
  • ✓High quality earnings: Operating CF exceeds net income
  • ✓Strong 5Y sales CAGR of 178.0%
  • ✓Trading at only 1.0x book value

✗Weaknesses

  • ✗Weak Piotroski F-Score: 2/9
  • ✗Negative free cash flow
  • ✗Trading more than 30% below 52-week high
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y10.27%
5Y178%
3Y-12.33%
TTM-91.16%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM-112.74%

EPS CAGR

10Y-
5Y-
3Y-
TTM-110.48%

ROCE

10Y Avg-24.52%
5Y Avg-18.31%
3Y Avg-25.34%
Latest-27.16%

Peer Comparison

Alzheimer's & Neurodegenerative
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Profit & Loss

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+1.61M1.05M27.52M955K814K853K200.58M53.91M91.37M135.16M
Revenue Growth %-0.97%-0.34%25.08%-0.97%-0.15%0.05%234.14%-0.73%0.7%0.48%
Cost of Goods Sold+58.44M119.53M134.55M101.18M50.84M74.88M0000
COGS % of Revenue36.37%113.3%4.89%105.95%62.45%87.79%----
Gross Profit+-56.83M-118.48M-107.03M-100.23M-50.02M-74.03M200.58M53.91M91.37M135.16M
Gross Margin %-35.37%-112.3%-3.89%-104.95%-61.45%-86.79%1%1%1%1%
Gross Profit Growth %-5.58%-1.08%0.1%0.06%0.5%-0.48%3.71%-0.73%0.7%0.48%
Operating Expenses+81.54M160.59M182.77M143.66M35.67M38.7M128.6M185.46M282.41M289.72M
OpEx % of Revenue50.74%152.22%6.64%150.43%43.83%45.37%0.64%3.44%3.09%2.14%
Selling, General & Admin23.11M41.06M48.23M42.48M35.74M38.7M46.32M49.9M61.84M67.2M
SG&A % of Revenue14.38%38.92%1.75%44.48%43.9%45.37%0.23%0.93%0.68%0.5%
Research & Development58.44M119.53M134.55M101.18M50.84M75.09M82.28M135.56M220.57M222.52M
R&D % of Revenue36.37%113.3%4.89%105.95%62.45%88.03%0.41%2.51%2.41%1.65%
Other Operating Expenses26K571K-2.35M2.74M-50.9M-75.09M0000
Operating Income+-79.94M-159.53M-155.25M-158.85M-85.7M-112.73M71.97M-131.56M-191.04M-154.56M
Operating Margin %-49.74%-151.22%-5.64%-166.34%-105.28%-132.16%0.36%-2.44%-2.09%-1.14%
Operating Income Growth %-11.02%-1%0.03%-0.02%0.46%-0.32%1.64%-2.83%-0.45%0.19%
EBITDA+-79.13M-157.11M-152.19M-155.64M-84.13M-111.22M73.09M-130.81M-190.11M-153.67M
EBITDA Margin %-49.24%-148.92%-5.53%-162.97%-103.36%-130.39%0.36%-2.43%-2.08%-1.14%
EBITDA Growth %-12.4%-0.99%0.03%-0.02%0.46%-0.32%1.66%-2.79%-0.45%0.19%
D&A (Non-Cash Add-back)806K2.43M3.07M3.22M1.56M1.51M1.11M744K928K893K
EBIT-79.94M-158.96M-153.91M-152.42M-85.76M-112.73M71.97M-131.56M-191.04M-154.56M
Net Interest Income+196K556K-142K2.69M8.2M1.37M42K6.35M31.01M25.82M
Interest Income196K1.42M3.55M6.39M8.2M1.37M42K6.35M31.01M25.82M
Interest Expense0863K3.69M3.7M000000
Other Income/Expense26K571K-2.35M2.74M8.4M1.87M-54K5.95M30.56M25.63M
Pretax Income+-79.91M-158.96M-157.6M-156.12M-77.3M-110.86M71.92M-125.61M-160.48M-128.93M
Pretax Margin %-49.73%-150.68%-5.73%-163.47%-94.96%-129.97%0.36%-2.33%-1.76%-0.95%
Income Tax+701K1.14M-4.37M-470K379K283K4.95M-8.66M-13.45M-6.62M
Effective Tax Rate %1.01%1.01%0.97%1%1%1%0.93%0.93%0.92%0.95%
Net Income+-80.61M-160.11M-153.24M-155.65M-77.68M-111.14M66.97M-116.95M-147.03M-122.31M
Net Margin %-50.16%-151.76%-5.57%-162.98%-95.43%-130.3%0.33%-2.17%-1.61%-0.9%
Net Income Growth %-10.27%-0.99%0.04%-0.02%0.5%-0.43%1.6%-2.75%-0.26%0.17%
Net Income (Continuing)-80.61M-160.11M-153.24M-155.65M-77.68M-111.14M66.97M-116.95M-147.03M-122.31M
Discontinued Operations0000000000
Minority Interest0000000000
EPS (Diluted)+-2.66-4.66-4.07-3.93-1.95-2.781.38-2.47-2.76-2.27
EPS Growth %-8.17%-0.75%0.13%0.03%0.5%-0.43%1.5%-2.79%-0.12%0.18%
EPS (Basic)-2.66-4.66-4.07-3.93-1.95-2.781.51-2.47-2.76-2.27
Diluted Shares Outstanding30.33M34.35M37.65M39.56M39.88M39.91M48.46M47.37M53.22M53.77M
Basic Shares Outstanding30.33M34.35M37.65M39.56M39.88M39.91M44.23M47.37M53.22M53.77M
Dividend Payout Ratio----------

Balance Sheet

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+377.4M391.36M426.33M431.39M378.38M299.28M584.81M719.1M639.28M485.41M
Cash & Short-Term Investments370.59M386.92M417.62M427.66M375.72M295.38M579.09M710.41M618.83M471.39M
Cash Only370.59M386.92M417.62M427.66M375.72M295.38M579.09M710.41M618.83M471.39M
Short-Term Investments0000000000
Accounts Receivable509K178K240K2K68K15K13K62K5.16M0
Days Sales Outstanding115.6161.583.180.7630.496.420.020.4220.61-
Inventory-509K-178K-240K0000000
Days Inventory Outstanding----------
Other Current Assets000001.35M766K1.71M3.49M1.17M
Total Non-Current Assets+7.83M68.61M70M67.41M40.89M33.69M24.56M38.94M57.1M61.7M
Property, Plant & Equipment3.86M56.45M54.99M52.84M27.15M20.36M14.13M8.01M16M13.79M
Fixed Asset Turnover0.42x0.02x0.50x0.02x0.03x0.04x14.19x6.73x5.71x9.80x
Goodwill0000000000
Intangible Assets0000000000
Long-Term Investments04.06M4.06M4.06M00000860K
Other Non-Current Assets1.12M6.25M6.9M4.87M3.79M1.69M3.35M12.72M7.21M3.81M
Total Assets+385.24M459.98M496.33M498.8M419.27M332.98M609.37M758.03M696.38M547.11M
Asset Turnover0.00x0.00x0.06x0.00x0.00x0.00x0.33x0.07x0.13x0.25x
Asset Growth %0.27%0.19%0.08%0%-0.16%-0.21%0.83%0.24%-0.08%-0.21%
Total Current Liabilities+22.22M41.08M37.37M14.93M17.71M25.85M33.45M50.15M56.89M48.5M
Accounts Payable4.52M13.07M13.63M1.47M1.24M4.12M3.69M9.27M25.39M7.77M
Days Payables Outstanding28.2239.9136.985.38.9220.07----
Short-Term Debt0000000000
Deferred Revenue (Current)284K363K-857K1000K001000K1000K01000K
Other Current Liabilities804K1.87M1.72M837K322K516K405K503K2.13M29.27M
Current Ratio16.99x9.53x11.41x28.90x21.36x11.58x17.48x14.34x11.24x10.01x
Quick Ratio17.01x9.53x11.41x28.90x21.36x11.58x17.48x14.34x11.24x10.01x
Cash Conversion Cycle----------
Total Non-Current Liabilities+2.35M53.5M51.77M160.87M128.63M123.12M109.87M85.85M78.13M11.68M
Long-Term Debt0000000000
Capital Lease Obligations051.32M51.52M49.9M17.84M12.33M6.39M010.72M8.23M
Deferred Tax Liabilities0-2.08M-254K-49.9M000000
Other Non-Current Liabilities2.35M2.18M254K110.97M553K553K553K553K00
Total Liabilities24.57M94.57M89.14M175.8M146.35M148.97M143.32M135.99M135.02M60.18M
Total Debt+051.32M52.25M51.55M22.94M17.84M12.33M6.47M11.84M10.84M
Net Debt-370.59M-335.6M-365.37M-376.11M-352.78M-277.54M-566.77M-703.93M-607M-460.55M
Debt / Equity-0.14x0.13x0.16x0.08x0.10x0.03x0.01x0.02x0.02x
Debt / EBITDA------0.17x---
Net Debt / EBITDA-------7.75x---
Interest Coverage--184.86x-42.10x-42.97x------
Total Equity+360.67M365.4M407.19M323M272.92M184.01M466.04M622.04M561.37M486.93M
Equity Growth %0.24%0.01%0.11%-0.21%-0.16%-0.33%1.53%0.33%-0.1%-0.13%
Book Value per Share11.8910.6410.818.166.844.619.6213.1310.559.06
Total Shareholders' Equity360.67M365.4M407.19M323M272.92M184.01M466.04M622.04M561.37M486.93M
Common Stock317K348K385K399K399K399K466K521K537K538K
Retained Earnings-129.1M-289.21M-442.35M-598M-671.88M-783.03M-716.05M-833M-980.03M-1.1B
Treasury Stock0000000000
Accumulated OCI-5.34M-7.67M-7.74M-10.5M000000
Minority Interest0000000000

Cash Flow

Dec 2015Dec 2016Dec 2017Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-62.45M-117.27M-131.18M-28.28M-52.97M-80.36M92.61M-108.82M-133.91M-150.05M
Operating CF Margin %-38.86%-111.16%-4.77%-29.61%-65.07%-94.21%0.46%-2.02%-1.47%-1.11%
Operating CF Growth %-90.44%-0.88%-0.12%0.78%-0.87%-0.52%2.15%-2.18%-0.23%-0.12%
Net Income-80.61M-160.11M-153.24M-155.65M-77.68M-111.14M66.97M-116.95M-147.03M-122.31M
Depreciation & Amortization806K2.43M3.07M3.22M6.82M1.51M1.11M744K928K893K
Stock-Based Compensation10.41M24.93M26.76M27.01M23.59M22.01M24.66M31.32M40.91M45.96M
Deferred Taxes-963K-3.25M-2.2M-1.59M-1.25M-1.69M4.57M-11.13M-15.69M-9.35M
Other Non-Cash Items-3.57M-156K1.59M4.28M05.46M5.69M6M7.5M2.69M
Working Capital Changes11.47M18.89M-7.16M94.45M-4.45M3.48M-10.4M-18.8M-20.53M-67.94M
Change in Receivables1.25M331K-62K238K053K15K0-5.16M5.16M
Change in Inventory-356.12M-346.92M-396.2M9.6M0000-8.9M0
Change in Payables11.16M15.19M147K-25.63M-78K7.73M-492K11.87M22.86M-18.3M
Cash from Investing+-1.38M-16.64M-3.52M-1.73M-547K-196K-575K-464K-2.77M-298K
Capital Expenditures-1.38M-16.64M-3.63M-1.77M-555K-196K-575K-464K-2.81M-298K
CapEx % of Revenue0.86%15.78%0.13%1.85%0.68%0.23%0%0.01%0.03%0%
Acquisitions----------
Investments----------
Other Investing00105K39K8K00037K0
Cash from Financing+140.84M154.31M165.4M40.04M228K215K190.33M241.46M45.1M1.55M
Debt Issued (Net)----------
Equity Issued (Net)----------
Dividends Paid0000000000
Share Repurchases----------
Other Financing9.5M25.7M17.84M4.69M228K215K15.54M17.84M21.52M1.91M
Net Change in Cash----------
Free Cash Flow+-63.84M-133.91M-134.81M-30.04M-53.52M-80.56M92.03M-109.28M-136.72M-150.35M
FCF Margin %-39.72%-126.93%-4.9%-31.46%-65.75%-94.44%0.46%-2.03%-1.5%-1.11%
FCF Growth %-51.8%-1.1%-0.01%0.78%-0.78%-0.51%2.14%-2.19%-0.25%-0.1%
FCF per Share-2.11-3.90-3.58-0.76-1.34-2.021.90-2.31-2.57-2.80
FCF Conversion (FCF/Net Income)0.77x0.73x0.86x0.18x0.68x0.72x1.38x0.93x0.91x1.23x
Interest Paid0000000000
Taxes Paid442K575K294K01.58M1.37M580K2.66M1.55M3.17M

Key Ratios

Metric2015201620172018201920202021202220232024
Return on Equity (ROE)-24.78%-44.1%-39.67%-42.63%-26.07%-48.65%20.61%-21.5%-24.85%-23.34%
Return on Invested Capital (ROIC)--1203.55%-325.18%-------439.41%
Gross Margin-3536.53%-11230.24%-388.92%-10495.08%-6145.21%-8678.9%100%100%100%100%
Net Margin-5016.3%-15176.11%-556.84%-16297.91%-9542.63%-13029.78%33.39%-216.95%-160.92%-90.49%
Debt / Equity-0.14x0.13x0.16x0.08x0.10x0.03x0.01x0.02x0.02x
Interest Coverage--184.86x-42.10x-42.97x------
FCF Conversion0.77x0.73x0.86x0.18x0.68x0.72x1.38x0.93x0.91x1.23x
Revenue Growth-96.84%-34.35%2508.44%-96.53%-14.76%4.79%23414.3%-73.13%69.5%47.92%

Revenue by Segment

20202021202220232024
Collaboration564K139.83M13.86M91.32M135.11M
Collaboration Growth-24693.09%-90.09%559.11%47.95%
License289K--50K50K
License Growth----0.00%
US Rights and Global Rights--85.3M--
US Rights and Global Rights Growth-----
Collaboration Program, US Rights-24.9M13.9M--
Collaboration Program, US Rights Growth---44.18%--

Frequently Asked Questions

Growth & Financials

Prothena Corporation plc (PRTA) reported $11.8M in revenue for fiscal year 2024. This represents a 2225% increase from $0.5M in 2011.

Prothena Corporation plc (PRTA) grew revenue by 47.9% over the past year. This is strong growth.

Prothena Corporation plc (PRTA) reported a net loss of $280.5M for fiscal year 2024.

Dividend & Returns

Prothena Corporation plc (PRTA) has a return on equity (ROE) of -23.3%. Negative ROE indicates the company is unprofitable.

Prothena Corporation plc (PRTA) had negative free cash flow of $188.2M in fiscal year 2024, likely due to heavy capital investments.

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