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Zentalis Pharmaceuticals, Inc. (ZNTL) 10-Year Financial Performance & Capital Metrics

ZNTL • • Industrial / General
HealthcareBiotechnologyOncology TherapeuticsSolid Tumor Oncology
AboutZentalis Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, focuses on discovering and developing small molecule therapeutics for the treatment of various cancers. Its lead product candidate includes the ZN-c3, an inhibitor of WEE1, a protein tyrosine kinase, which is in Phase 2 clinical trial for the treatment of advanced solid tumors; Phase 1/2 clinical trial for the treatment of advanced solid tumors as a monotherapy and in an ongoing Phase 1b clinical trial in combination with chemotherapy in patients with platinum resistant ovarian cancer; and Phase 2 monotherapy trial for a tumor agnostic, predictive biomarker. The company's other lead product candidate includes ZN-c5, an oral selective estrogen receptor degrader that is in a Phase 1/2 clinical trial for the treatment of advanced estrogen receptor-positive, human epidermal growth factor receptor 2-negative, or advanced or metastatic breast cancer. In addition, it is involved in developing ZN-d5, a selective inhibitor of B-cell lymphoma 2 that is in a Phase 1 clinical trial for the treatment of non-Hodgkin's lymphoma and acute myelogenous leukemia; and ZN-e4, an irreversible inhibitor of mutant epidermal growth factor receptor, which is in Phase 1/2 clinical trial for the treatment of advanced non-small cell lung cancer. Further, the company is developing BCL-xL heterobifunctional degraders based on E3 ligases not expressed in platelets, allowing for the avoidance of dose-limiting thrombocytopenia associated with BCL-xL inhibitors. Zentalis Pharmaceuticals, Inc. has licensing agreements and strategic collaborations with Recurium IP Holdings, LLC; Mayo Foundation for Medical Education and Research; SciClone Pharmaceuticals International (Cayman) Development Ltd.; Pfizer, Inc.; Eli Lilly and Company; GlaxoSmithKline, and Zentera Therapeutics (Cayman), Ltd. The company was incorporated in 2014 and is based in New York, New York.Show more
  • Revenue $67M
  • EBITDA -$190M +36.3%
  • Net Income -$166M +43.2%
  • EPS (Diluted) -2.33 +47.9%
  • Gross Margin 100%
  • EBITDA Margin -281.65%
  • Operating Margin -283.57%
  • Net Margin -245.96%
  • ROE -42.82% +36.1%
  • ROIC -35.8% +28.8%
  • Debt/Equity 0.13 +20.9%
  • Interest Coverage -
Technical Analysis

Key Insights

Based on financial data analysis

✓Strengths

  • ✓Momentum leader: RS Rating 96 (top 4%)
  • ✓Trading at only 0.7x book value

✗Weaknesses

  • ✗Negative free cash flow
  • ✗Low asset turnover indicates capital-intensive operations

* These insights are generated automatically based on available financial data. Please conduct your own research before making investment decisions.

Price & Volume

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Growth Metrics

Revenue CAGR

10Y-
5Y-
3Y-
TTM-33.76%

Profit (Net Income) CAGR

10Y-
5Y-
3Y-
TTM16.72%

EPS CAGR

10Y-
5Y-
3Y-
TTM17.46%

ROCE

10Y Avg-60.45%
5Y Avg-53.63%
3Y Avg-51.21%
Latest-43.94%

Peer Comparison

Solid Tumor Oncology
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Sector-Specific
NameMarket CapCurrent PriceP/E RatioRevenue Growth 1YNet MarginROEFCF YieldDebt/Equity
TLXTelix Pharmaceuticals Limited2.49B7.4353.0755.85%3.98%15.63%0.36%1.02
EXELExelixis, Inc.12.18B45.4425.8218.49%29.63%31.37%5.2%0.09
BBOTBridgeBio Oncology Therapeutics Inc.919.87M11.5025-25.73%
INBXInhibrx Biosciences, Inc.1.04B71.800.62-88.89%-110.78%-421.09%0.06
NUVBNuvation Bio Inc.2.1B6.14-2.91-8.13%-66.74%0.02
RLAYRelay Therapeutics, Inc.1.32B7.63-3.23-60.83%-26.71%-48.97%0.06
ORICORIC Pharmaceuticals, Inc.1.12B11.52-6.30-33.24%0.01
ZLABZai Lab Limited2.09B18.82-7.2449.59%-46.83%-27.21%0.18

Profit & Loss

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Sales/Revenue+14K0000067.42M
Revenue Growth %--1%-----
Cost of Goods Sold+0000000
COGS % of Revenue-------
Gross Profit+14K0000067.42M
Gross Margin %1%-----1%
Gross Profit Growth %--1%-----
Operating Expenses+23.8M46.84M118.79M216.54M227.29M299.51M258.62M
OpEx % of Revenue1699.79%-----3.84%
Selling, General & Admin4.88M8.46M33.89M40.94M54.55M59.4M87.11M
SG&A % of Revenue348.29%-----1.29%
Research & Development18.92M38.39M84.9M175.6M172.73M235.16M167.77M
R&D % of Revenue1351.5%-----2.49%
Other Operating Expenses000004.95M3.74M
Operating Income+-23.78M-46.84M-118.79M-216.54M-227.29M-299.51M-191.19M
Operating Margin %-1698.79%------2.84%
Operating Income Growth %--0.97%-1.54%-0.82%-0.05%-0.32%0.36%
EBITDA+-23.73M-46.73M-118.63M-216M-225.86M-298.12M-189.91M
EBITDA Margin %-1695.11%------2.82%
EBITDA Growth %--0.97%-1.54%-0.82%-0.05%-0.32%0.36%
D&A (Non-Cash Add-back)51.49K111K160K544K1.43M1.39M1.29M
EBIT-23.78M-46.84M-118.79M-207.74M-227.29M-248.99M-187.46M
Net Interest Income+355K498K00-2.57M00
Interest Income355K498K002.26K00
Interest Expense00002.58M00
Other Income/Expense355K482K683K50.15M-10.29M6.6M25.5M
Pretax Income+-23.43M-46.36M-118.1M-166.39M-237.58M-292.91M-165.69M
Pretax Margin %-1673.43%------2.46%
Income Tax+4K15K444K-297K-469K-601K177K
Effective Tax Rate %0.9%0.98%1%0.95%1%1%1%
Net Income+-21.07M-45.66M-117.84M-158.72M-236.81M-292.19M-165.84M
Net Margin %-1504.79%------2.46%
Net Income Growth %--1.17%-1.58%-0.35%-0.49%-0.23%0.43%
Net Income (Continuing)-23.43M-46.38M-118.55M-166.09M-237.11M-292.31M-165.87M
Discontinued Operations0000000
Minority Interest7.54M6.82M24.8M528K221K107K0
EPS (Diluted)+-1.17-1.29-2.87-3.72-4.48-4.47-2.33
EPS Growth %--0.1%-1.22%-0.3%-0.2%0%0.48%
EPS (Basic)-1.17-1.29-2.87-3.72-4.48-4.47-2.33
Diluted Shares Outstanding18.06M35.88M41.04M42.69M52.86M65.41M71.08M
Basic Shares Outstanding18.06M35.88M41.04M42.69M52.86M65.41M71.08M
Dividend Payout Ratio-------

Balance Sheet

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Total Current Assets+26.68M68.89M345.1M350.77M451.93M496.72M386.07M
Cash & Short-Term Investments25.15M67.25M338.5M340.13M437.37M482.92M371.08M
Cash Only25.15M67.25M54.95M59.96M43.07M28.04M33.9M
Short-Term Investments00283.55M280.17M394.3M454.88M337.18M
Accounts Receivable917K140K02.63M005M
Days Sales Outstanding23.91K-----27.07
Inventory0000000
Days Inventory Outstanding-------
Other Current Assets00417K014.56M13.8M0
Total Non-Current Assets+14.32M19.34M20.45M121.25M101.52M65.31M44.27M
Property, Plant & Equipment260K2.84M3.62M52.84M50.08M41.73M37.23M
Fixed Asset Turnover0.05x-----1.81x
Goodwill3.74M3.74M3.74M3.74M3.74M3.74M0
Intangible Assets8.8M8.8M8.8M0000
Long-Term Investments-46.26K243K040.12M23.84M2.68M0
Other Non-Current Assets1.52M2.97M4.3M7.04M9.72M6.82M7.04M
Total Assets+41M88.23M365.56M472.02M553.46M562.03M430.34M
Asset Turnover0.00x-----0.16x
Asset Growth %-1.15%3.14%0.29%0.17%0.02%-0.23%
Total Current Liabilities+6.21M14.9M28.6M43.94M56.65M69.37M52.73M
Accounts Payable3.43M4.29M8.66M11.59M11.25M14.93M7.44M
Days Payables Outstanding-------
Short-Term Debt0781K01.45M2.16M2.62M0
Deferred Revenue (Current)223.42K0000281K0
Other Current Liabilities223K6.85M410K20.68M43.24M-2.9M0
Current Ratio4.30x4.62x12.07x7.98x7.98x7.16x7.32x
Quick Ratio4.30x4.62x12.07x7.98x7.98x7.16x7.32x
Cash Conversion Cycle-------
Total Non-Current Liabilities+2.48M4.91M3.58M63.6M62.79M55.27M40.43M
Long-Term Debt0000000
Capital Lease Obligations01.7M1.1M44.46M45.17M43.15M39.58M
Deferred Tax Liabilities2.46M3.21M019.14M15M10.34M0
Other Non-Current Liabilities21K5K2.48M02.62M1.78M849K
Total Liabilities8.69M19.81M32.18M107.54M119.43M124.64M93.15M
Total Debt+02.48M2M45.91M47.33M45.77M42.65M
Net Debt-25.15M-64.77M-52.95M-14.04M4.26M17.73M8.75M
Debt / Equity-0.04x0.01x0.13x0.11x0.10x0.13x
Debt / EBITDA-------
Net Debt / EBITDA-------
Interest Coverage-----88.27x--
Total Equity+32.31M68.42M333.38M364.48M434.02M437.39M337.19M
Equity Growth %-1.12%3.87%0.09%0.19%0.01%-0.23%
Book Value per Share1.791.918.128.548.216.694.74
Total Shareholders' Equity24.77M61.6M308.58M363.95M433.8M437.28M337.19M
Common Stock2.27M2.89M41K45K59K70K71K
Retained Earnings-37.33M-82.99M-200.83M-359.56M-596.37M-888.56M-1.05B
Treasury Stock0000000
Accumulated OCI-56K036K-125K-1.35M2.19M558K
Minority Interest7.54M6.82M24.8M528K221K107K0

Cash Flow

Dec 2018Dec 2019Dec 2020Dec 2021Dec 2022Dec 2023Dec 2024
Cash from Operations+-24.25M-39.14M-86.83M-154.09M-163.75M-207.82M-170.86M
Operating CF Margin %-1732.21%------2.53%
Operating CF Growth %--0.61%-1.22%-0.77%-0.06%-0.27%0.18%
Net Income-23.43M-46.38M-118.55M-166.09M-237.11M-292.19M-165.87M
Depreciation & Amortization51K111K160K544K1.43M1.39M1.29M
Stock-Based Compensation308K617K23.15M35.74M46.84M54.82M67.27M
Deferred Taxes2.37M017K-2.51M-769K-853K0
Other Non-Cash Items-2.37M0556K-38.38M12.61M23.15M-57.01M
Working Capital Changes-1.18M6.51M7.84M16.61M13.25M5.86M-16.54M
Change in Receivables-254K777K-277K413K00-5M
Change in Inventory-1.86M0-5.52M0000
Change in Payables977K7.12M14.31M13.96M15.53M10.92M-18.02M
Cash from Investing+-227K-352K-284.83M-18.11M-114.18M-44.46M176.56M
Capital Expenditures-227K-352K-758K-6.11M-2.55M-583K-221K
CapEx % of Revenue16.21%-----0%
Acquisitions-------
Investments-------
Other Investing00-18.42M0-111.63K00
Cash from Financing+9.47M81.83M360.44M178.52M261.04M237.3M108K
Debt Issued (Net)-------
Equity Issued (Net)-------
Dividends Paid0000000
Share Repurchases-------
Other Financing0-46K18.42M-1.15M00-241K
Net Change in Cash-------
Free Cash Flow+-24.48M-39.49M-87.58M-160.2M-166.3M-208.41M-171.08M
FCF Margin %-1748.43%------2.54%
FCF Growth %--0.61%-1.22%-0.83%-0.04%-0.25%0.18%
FCF per Share-1.36-1.10-2.13-3.75-3.15-3.19-2.41
FCF Conversion (FCF/Net Income)1.15x0.86x0.74x0.97x0.69x0.71x1.03x
Interest Paid0000000
Taxes Paid4K15K18K20K12K140K359K

Key Ratios

Metric2018201920202021202220232024
Return on Equity (ROE)-65.21%-90.67%-58.66%-45.49%-59.31%-67.06%-42.82%
Return on Invested Capital (ROIC)-249.4%-650.44%-62.72%-51.49%-43.23%-50.29%-35.8%
Gross Margin100%-----100%
Net Margin-150478.57%------245.96%
Debt / Equity-0.04x0.01x0.13x0.11x0.10x0.13x
Interest Coverage-----88.27x--
FCF Conversion1.15x0.86x0.74x0.97x0.69x0.71x1.03x
Revenue Growth--100%-----

Revenue by Segment

2024
Reportable67.42M
Reportable Growth-

Frequently Asked Questions

Growth & Financials

Zentalis Pharmaceuticals, Inc. (ZNTL) reported $26.9M in revenue for fiscal year 2024. This represents a 191793% increase from $0.0M in 2018.

Zentalis Pharmaceuticals, Inc. (ZNTL) grew revenue by 0.0% over the past year. Growth has been modest.

Zentalis Pharmaceuticals, Inc. (ZNTL) reported a net loss of $149.3M for fiscal year 2024.

Dividend & Returns

Zentalis Pharmaceuticals, Inc. (ZNTL) has a return on equity (ROE) of -42.8%. Negative ROE indicates the company is unprofitable.

Zentalis Pharmaceuticals, Inc. (ZNTL) had negative free cash flow of $134.0M in fiscal year 2024, likely due to heavy capital investments.

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